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At least 1,621 records · Page 90Linked to original sources
PubMed1991

Health care workers with AIDS. National surveillance update.

OBJECTIVES: To characterize health care workers with the acquired immunodeficiency syndrome (AIDS) in the United States and to evaluate the role of occupational transmission of the human immunodeficiency virus (HIV). DATA SOURCE: National AIDS surveillance data. METHODS: Health care workers with AIDS are reported to the Centers for Disease Control by state and local health departments. Health care workers who do not report a nonoccupational risk for HIV infection are termed undetermined risk cases and are investigated by health departments using a standard protocol. RESULTS: Through June 30, 1990, there were 5425 cases of AIDS in health care workers reported in the United States. Three of these workers developed AIDS following well-documented occupational exposure to HIV-infected blood. Of the 539 health care workers initially reported without a nonoccupational risk, follow-up investigations were completed for 303. Nonoccupational risk factors were established for 237 (78.2%) of the 303 investigated health care workers; 66 workers (21.8%) remained in the undetermined category. Follow-up information was incomplete for 236 health care workers who also remained in the undetermined category, resulting in 5120 health care workers (94.4%) with AIDS with nonoccupational risks for HIV infection. Overall, health care workers were more likely than non-health care workers with AIDS to have an undetermined risk for HIV infection (5.6% vs 2.8%; P less than .001). While many of the 66 investigated health care workers had jobs involving contact with patients and/or potential contact with blood, none reported percutaneous, mucous membrane, or cutaneous exposures to blood or body fluids known to be infected with HIV. CONCLUSION: Surveillance data suggest that most health care workers with AIDS acquired their HIV infection through a nonoccupational route.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[The HIV epidemiology in province of Modena: use of two different sources of data].

OBJECTIVE: to analyse demographic characteristics and risk factors of people living with HIV and to compare data from the surveillance system for new HIV diagnoses with those from the National AIDS Registry (RAIDS). DESIGN: comparison of two surveillance systems. SETTING: province of Modena. PARTICIPANTS: cases reported to the RAIDS and to the HIV surveillance system, from 1985 to 2004 regarding residents in the province of Modena. MAIN OUTCOMES: number of cases and incidence, by exposure categories, age, and gender. RESULTS: from 1985 to 2004, 615AIDS cases and 1731 new HIV diagnoses were reported among residence in the province of Modena. The incidence of AIDS progressively decreased after 1995, whereas incidence of new HIV diagnoses remained stable since 1994 with annual rates up to three-fold higher than those reported for the AIDS cases. Individuals with a new HIV diagnosis were younger (<30 years of age), with a higher proportion of females and heterosexuals compared to AIDS cases. The most represented age group among AIDS cases was 30-49 years whereas it was <30 years for newly diagnosed HIV cases. The proportion of intravenous drug users decreased over time both among new AIDS cases and new HIV diagnoses, whereas the proportion of cases attributed to sexual transmission increased. The proportion of foreigners among newly diagnosed HIV cases was twice as high as among AIDS cases. CONCLUSIONS: this study shows that, especially after the introduction of highly active antiretroviral therapies, information on AIDS cases has become less representative of the trends to HIV epidemic. Therefore, AIDS surveillance systems should be combined with local surveillance systems on new HIV diagnoses.

Acquired Immunodeficiency Syndrome↗
PubMed1991

Performance/outcome measures for area health board diabetes services.

OBJECT: to examine the validity of performance indicators nominated by the Department of Health for area health board diabetes services for 1990-91. METHODS: by examination of admission/discharge data for the Otago region for the years 1985-9, together with a survey of randomly chosen clinical notes to quantify errors in the admission/discharge database. RESULTS: of the proposed indicators, there is marked variation in statistical significance, primarily as a consequence of the often small number of numerator events and denominator populations involved. Further the rates and statistical significance vary markedly depending on the interpretation of the numerator events to be included. Diabetes as the principal diagnosis was correctly recorded in 100% of notes examined. Of these the clinical diagnosis was incorrectly described in the discharge summary in 2% of cases. In 46% of cases where diabetes should have been recorded as a subsidiary diagnosis, it was not. CONCLUSIONS: the potential exists for significant misinterpretation of these indicators with the proposed data sources. Using routinely collected data there are potentially more robust indicators applicable for use at an area health board level. Much work needs to be done if these indicators are to truly reflect all facets of the performance of a diabetes service.

Diabetes Mellitus↗
PubMed1990

Occupational cancer in Denmark. Cancer incidence in the 1970 census population.

Data sources and creation of data files. The cohort of persons who were 20-64 years of age at the time of the 1970 census has been followed for cancer incidence for a ten-year period. The study was made by linkage of individual records from the 1970 census, the Central Population Register, death certificates, and cancer registrations. Data were included on individual characteristics recorded in the census on prevalent cancer cases at the time of the census and on deaths, emigrations, and incident cancer cases during the ten-year follow-up period. The study includes a total of 2.8 million persons, of whom 2.0 million were economically active at the time of the 1970 census. A total of 115,000 incident cancer cases were registered during the follow-up period, and 77,000 of these occurred in persons who were economically active in 1970. The classifications used in the census included 218 codes for occupation and 245 codes for industry. The Cancer Registry data included 639 codes for diagnosis. Cancer incidence by social groups in Denmark. The cancer incidence was tabulated across 32 socioeconomic groups for 43 cancer sites among the men and 45 cancer sites among the women. The study showed an almost twofold difference in the overall cancer incidence between the socioeconomic groups of the men. Self-employed farmers were at low risk (RR 0.68), and unskilled workers in shipping/fishing were at high risk (RR 1.28) when the cancer incidence among all economically active men was used for the comparison. The social pattern in cancer incidence correlated well with the pattern for cancer mortality among men. As a rough estimate, the cumulative incidence for all cancer among persons under 75 years of age could be reduced by 32% if all Danish men had the cancer incidence of farmers. There was a fivefold or larger difference between the socioeconomic groups in the incidence for nine cancer sites. These nine cancer sites together represented 7% of the cumulative incidence for all cancer. Estimated in a similar way, the cumulative incidence could be reduced by 44% if all Danish men had the site-specific cancer incidence of the respective low-risk groups. The overall cancer incidence among the women varied from a relative risk of 0.71 for unskilled workers in agriculture to a relative risk of 1.18 for self-employed women in other industries I (dentists, lawyers, etc) when the cancer incidence among all economically active women was used for the comparison.(ABSTRACT TRUNCATED AT 400 WORDS)

Adult↗
PubMed1984

Independent living outcomes in spinal cord injury: multivariate analyses.

This paper presents results of a study designed to isolate those medical, personal, and environmental factors that best predict a spinal cord injured (SCI) person's ability to live independently following discharge from medical rehabilitation. A formal research model is used to identify the most promising dependent and independent variables. The principal data source is an extensive data file of 111 persons with SCI who were discharged from 10 medical rehabilitation centers across the nation. The two main independent living (IL) outcome variables are (1) a person's ability to live in a less restrictive environment, and (2) a person's ability to live productively--not only in terms of gainful employment but also in terms of other contributions to community and family life. Using multiple regression analysis, the paper reports that approximately 63% of the variance in IL outcome can be explained. The most important predictors of IL outcome are marital status, education, transportation barriers, economic disincentives, and the severity of a person's disability as measured by the Barthel index. All predictors are statistically significant. The paper concludes with implications for medical rehabilitation practice and disability policy.

Activities of Daily Living↗
PubMed1995

Impact of varying panel membership on ratings of appropriateness in consensus panels: a comparison of a multi- and single disciplinary panel.

OBJECTIVE: The objective of the study was to examine the appropriateness ratings for the use of spinal manipulation for low back pain of a multidisciplinary panel of medical and chiropractic physicians, and those of a panel composed only of chiropractic physicians. DATA SOURCES: The study analyzed data from two consensus panels conducted at RAND in 1990 and 1991. STUDY DESIGN: The study design followed that of the traditional RAND consensus panels. Nine individuals comprised each panel, and each panelist was asked to rate, on a nine-point scale, the indications for spinal manipulation twice, the first time alone and the second time jointly with the panel. DATA COLLECTION: The ratings of the panelists from both groups, for both round one and round two, were collated and compared. PRINCIPAL FINDINGS: While both panels were more likely to rate the indications as inappropriate than appropriate, the single disciplinary panel was more likely to rate an indication as appropriate than the multidisciplinary panel. CONCLUSION: The composition of a panel clearly influences the ratings and those who use a given procedure in practice, in this case manipulation, are more likely to rate it as appropriate than those who do not use the procedure.

Chiropractic↗
PubMed1995

Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure. Collaborative Group on ACE Inhibitor Trials.

OBJECTIVE: To evaluate the effect of angiotensin-converting enzyme (ACE) inhibitors on mortality and morbidity in patients with symptomatic congestive heart failure. DATA SOURCE AND STUDY SELECTION: Data were obtained for all completed, published or unpublished, randomized, placebo-controlled trials of ACE inhibitors that were at least 8 weeks in duration and had determined total mortality by intention to treat, regardless of sample size. Trials were identified based on literature review and correspondence with investigators and pharmaceutical firms. DATA EXTRACTION: Using standard tables, data were extracted by one author and confirmed where necessary by the other author or the principal investigator of the trial. Unpublished data were obtained by direct correspondence with the principal investigator of each study or pharmaceutical firm. DATA SYNTHESIS: The data for each outcome were combined using the Yusuf-Peto adaptation of the Mantel-Haenszel method. Overall, there was a statistically significant reduction in total mortality (odds ratio [OR], 0.77; 95% confidence interval [CI], 0.67 to 0.88; P < .001) and in the combined endpoint of mortality or hospitalization for congestive heart failure (OR, 0.65; 95% CI, 0.57 to 0.74; P < .001). Similar benefits were observed with several different ACE inhibitors, although the data were largely based on enalapril maleate, captopril, ramipril, quinapril hydrochloride, and lisinopril. Reductions for total mortality and the combined endpoint were similar for various subgroups examined (age, sex, etiology, and New York Heart Association class). However, patients with the lowest ejection fraction appeared to have the greatest benefit. The greatest effect was seen during the first 3 months, but additional benefit was observed during further treatment. The reduction in mortality was primarily due to fewer deaths from progressive heart failure (OR, 0.69; 95% CI, 0.58 to 0.83); point estimates for effects on sudden or presumed arrhythmic deaths (OR, 0.91; 95% CI, 0.73 to 1.12) and fatal myocardial infarction (OR, 0.82; 95% CI, 0.60 to 1.11) were less than 1 but were not significant. CONCLUSIONS: Total mortality and hospitalization for congestive heart failure are significantly reduced by ACE inhibitors with consistent effects in a broad range of patients.

Aged↗
PubMed1976

Comparative costs to the Medicare program of seven prepaid group practices and controls.

This research was conducted in order to compare costs to the Medicare program for providing health care service to old people enrolled in two forms of health delivery organization: open market and prepaid group practice (pgp). Two data sources were employed: cost data provided by the Social Security Administration for seven prepaid group practices in five SMSAs and northern California and interviews conducted with administrators of the prepaid groups to determine: organizational sponsorship, incentive structure, pattern of selectivity of patients, and resource availability. Major findings are: (1) Enrollees in prepaid groups incur higher physician costs. This includes services provided by practitioners in and outside the plans. (2) Overall, prepaid groups demonstrate savings to the Medicare program in provider-initiated services- in hospital care and extended care facility services, but not in home health care. (3) Reduced spending in the hospital component does not imply reduction in the extended care facility or home service. (4) Outpatient costs in the hospital are generally higher in the open market modes, probably because this mode of care is viewed as an alternative to physician visits. (5) The greatest cost savings to the Medicare program are demonstrated by groups which are relatively small, yet hospital-based.

Aged↗
PubMed1995

Estimating annual charges for ambulatory care from limited utilization data.

OBJECTIVE: This study explores the types of utilization information needed to produce a reasonable estimate of annual charges for ambulatory care that could be used in the absence of charge or cost data as an aggregate utilization measure. DATA SOURCE: Charge and utilization data from the RAND Health Insurance Experiment were used. STUDY DESIGN: Services provided to enrollees in the Health Insurance Experiment at each of the six sites for a one-year period were grouped into categories according to California Relative Value Studies (CRVS) codes. Using annual charges as the dependent variable, we evaluated linear regression models for their predictive accuracy, as indicated by adjusted R2-values. Categories of services were combined on the basis of clinical meaningfulness (e.g., all provider visits into one group), and predictive accuracy of models with these groupings of services examined. We examined model validity by applying the derived models to each of the 30 remaining site-years of data from the Health Insurance Experiment. PRINCIPAL FINDINGS: We were able to explain 84 percent of the variance in charges with a model containing counts of provider visits exclusive of mental health visits, mental health provider visits, days drugs were prescribed, days radiologic procedures were performed, procedural visits subdivided according to whether they were performed by a surgical or medical provider, days laboratory and/or pathology tests were performed, days a grouping of miscellaneous tests were performed, and days supplies were purchased. When applied to the validation data, this model predicted a mean of 77 percent of the variance and mean charges 102 +/- 9 percent of actual mean charges. A model with only the first four of the listed categories explained 77 percent of the variance in charges. CONCLUSIONS: Models using only counts of several broad categories of services perform rather well in predicting annual charges for ambulatory care.

Ambulatory Care↗
PubMed1994

Renaissance of tuberculosis in the 1990s: lessons for the nephrologist.

OBJECTIVE: To call attention to the worldwide increase in tuberculosis and to review the disease in peritoneal dialysis patients. DATA SOURCES: Recent epidemiological publications. DATA EXTRACTION: Epidemiological data summarized in tables and diagnostic and therapeutic recommendations reviewed. CONCLUSIONS: Tuberculosis is on the rise worldwide. Multiple drug-resistant strains are emerging, causing therapeutic problems. The role of atypical mycobacterial infections in continuous ambulatory peritoneal dialysis (CAPD) is reviewed. Early diagnosis of cases and thorough chemotherapy are advocated.

Humans↗
PubMed1994

Net economic costs of dementia in Canada.

OBJECTIVE: To estimate the net economic costs of dementia in Canada in 1991 by comparing costs related to elderly patients with dementia with those related to elderly people without dementia. DESIGN: Cost-of-illness study. DATA SOURCES: Most of the data analysed in this study were from the Canadian Study of Health and Aging (CSHA), in which 10,263 Canadians aged 65 years and over were randomly selected, surveyed and, when appropriate, given clinical examinations. Data on patients with dementia and on people without cognitive impairment (control subjects) were used for this analysis. Data on activities of daily living (ADLs) were taken from a separate study under the CSHA, in which the principal caregivers of the subjects in the prevalence study were interviewed. SETTING: Community and institutional settings in Canada, excluding those in the territories. PATIENTS: All patients with dementia 65 years and older as determined from the CSHA. Patients with dementia under 65 were also considered. OUTCOME MEASURES: Costs of paid and unpaid services in the community, care in long-term care institutions, drugs, hospitalization, diagnosis and research. RESULTS: The total annual net cost of dementia was estimated to be over $3.9 billion. Costs associated with elderly patients in the community were estimated to be $1.25 billion ($615 million for paid services, $636 million for unpaid services), whereas costs for patients in long-term care institutions were $2.18 billion. Costs were about $74 million for drugs, hospitalization and diagnosis, $10 million for research and $389 million related to patients under age 65. CONCLUSION: The annual net economic cost of dementia in Canada is at least $3.9 billion. The most significant component of the total cost was for care in long-term care institutions and for assistance with ADLs by professionals, family and friends in the community. The economic burden of dementia is significant not only for patients, their families and friends, but also for society.

Aged↗