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[The efficacy of personal prevention measures in controlling the exposure to metals of welders].

Biological monitoring of welders employed in a power plant showed urinary nickel levels largely exceeding the reference values (Ni-U welders mean = 43.2, S.D. = 22.1 micrograms/24 h; Ni-U reference values mean = 2.7, S.D. = 1.4 micrograms/24 h). Subsequently urinary excretion levels of other metals (Cr, Zn, Fe, Mn, Cu, Al, Pb) were measured for a more complete assessment of occupational exposure of these subjects; only aluminum and lead were found to slightly exceed the reference values and correlate with urinary nickel levels. As a consequence of these results, some adjustments in personal prevention measures were introduced at the workplace; the subsequent biological monitoring checks showed a progressive reduction in urinary nickel excretion levels over time in all welders.

Adult↗

Searching for preventive measures of cardiovascular events in aged Japanese taxi drivers--the daily rhythm of cardiovascular risk factors during a night duty day.

Previous studies have shown that Japanese taxi drivers are exposed to more risk factors and have a higher mortality rate due to cardiovascular disease than other occupational groups. We investigated the effect of night taxi driving with a view to preventing acute events of cardiovascular disease among aged taxi drivers. Twenty-nine taxi drivers (41-67 years old) were examined for urine normetanephrine/creatinine, von Willebrand factor, anti-thrombin III, t-plasminogen activator-plasminogen activator inhibitor 1-complex, hematocrit, blood glucose and blood pressure in the morning and at midnight during a duty day and in the following morning. At the same time, the blood pressure and blood glucose of 46 taxi drivers (43-67 years old) in the morning after a night duty with little sleep and in the morning after daytime work and subsequent night sleep were compared. The results obtained indicate that the aggravation of sympathetic nervous system functions with disturbed circadian rhythms, increased blood coagulation and blood concentration, endothelial injury and the elevation of blood glucose at midnight or the next morning were induced by their night work. These conditions are supposed to favour acute vascular events in aged taxi drivers. Preventive measures considered include social support for anticoagulant food and water intake, short exercise and walking as well as taking a rest and a nap during night work.

Adult↗

Widia tool grinding: the importance of primary prevention measures in reducing occupational exposure to cobalt.

An occupational health and industrial hygiene survey was carried out in Widia tool grinding industries in the area covered by Local Health Unit No. 60--Vimercate (Northern Italy). The principal objectives of the study were to assess occupational cobalt exposure, identify the measures required to improve the 'risk' situations, and implement specific health protocols. The results identified a variable level of occupational hazard in the tool grinding sector. An important factor in the containment of occupational exposure was, along with correct practical procedures, the existence of adequate primary prevention measures (aspiration systems over the machines). In the plants where good industrial hygiene conditions prevailed, environmental cobalt concentrations were below the TLV, whereas the levels recorded in plants with inadequate equipment were as much as 10 times the TLV. Similarly, urinary cobalt for the workers in these same plants was as much as 13 times higher than the reference population value. However, this was recorded in plants with good industrial hygiene conditions. After technical improvements, the results of biological monitoring showed an overall reduction in exposure indicator values.

Air Pollutants, Occupational↗

[Is Swiss national accident data useful for epidemiological studies if the latter is intended for validating preventive measures?].

In the general frame of an inquiry concerning the development of occupational health in Switzerland and its forthcoming place inside the Swiss health system, data on accidents were communicated to us by the Swiss National Accident Insurance Fund. In this paper, the question is raised whether those data may be effectively submitted to the epidemiological analysis in order to quantify the accident risk and to validate preventive measures. Results will be presented in a subsequent article.

Accidents, Occupational↗

From the discovery of risk factors for coronary artery disease to the application of preventive measures.

Hyperlipidemia and high blood pressure have clearly evolved as major risk factors for cardiovascular diseases. High fat intake, obesity, and cigarette smoking have been shown to be root causes of such risk. Ecologic correlations and case-control studies have provided evidence that hyperlipidemia and obesity certainly have their beginnings during childhood, and that the onset of cigarette smoking at a young age escalates the risk for coronary artery disease. Thus, preventive measures will have the greatest impact when applied at an early age. In fact, several fine comprehensive school health education programs (eg, Health Ahead/Heart Smart, Know Your Body) have demonstrated that behavior can be changed and that the risk factors for heart disease can be reduced. Such programs are most cost effective when they are multifactorial in nature and address health promotion on a broad scale. Therefore, comprehensive school health education programs should be a component of national health-care reform. The investment in early health education will pay off by deterring chronic diseases in adulthood and will thus contribute to a healthier nation.

Coronary Disease↗

[Urinary schistosomiasis: description of a case. Clinico-therapeutic considerations and preventive measures].

In Italy, imported cases of urinary schistosomiasis may be frequently undiagnosed, because the symptoms are mild and the number of schistosome eggs in urine is low. The Authors report one case of S. haematobium infection in whom the diagnosis was suspected on the basis of the anamnestic and clinical data and confirmed by the presence of typical eggs in urine and histologically in biopsies taken at cystoscopy. Moreover preventive measures are suggested for the individuals who go to those Countries where schistosomiasis is endemic.

Adult↗

[Preventive measures in bronchial provocation tests].

The author's own experiences together with the data from the literature are presented for application the bronchial provocation tests in the hospital and in out-patient's department for pulmonary disease. Contraindications and side effects in testing the nonspecific provocative agents are presented (metacholine, histamine, carbachol), in specific provocative agents as well as in exercise testing. These tests are relatively harmless if the preventive measures are taken into account.

Bronchial Provocation Tests↗

Health hazards and preventive measures of farm women. Emerging issues.

Currently, an increasing number of farms are family owned and women are directly involved in the farming operations as an independent manager or partner. Women play an important role in farm management by marketing farm products, purchasing materials, and financial planning. Because of this involvement, women can be exposed to potential health hazards that can result in chronic illness, debilitation, or death. This study explored and described health hazards affecting farm women in southeast Louisiana, preventive measures used by farm women, and their consistency in using protective equipment with varying levels of time commitment toward farm operations. This cross sectional study included women older than 18 whose family participated in farming operations. A stratified, random sample design with parishes comprising the strata and simple random selection without replacement within each stratum was used to select family addresses. A total of 519 women who met the criteria completed a structured 30 minute telephone interview conducted using The Louisiana Farm Health and Injury Survey instrument. Information elicited included farm work characteristics, prevention practices, and demographics. Results showed that women working 1 to 20 hours per week were less likely to wear personal protective equipment (PPE) than women working more than 20 hours per week. This included wearing seat belts on tractors; using hearing, eye, or breathing protection; and wearing gloves or boots. No differences were found between groups for use of skin protection, hair holders, or helmets on all terrain vehicles (ATVs). The researchers concluded that if nursing interventions such as teaching and counseling related to prevention methods could be provided, the incidence of acute and chronic illnesses and traumatic injury would decline.

Adult↗

Genital herpes and pregnancy--preventive measures.

Genital herpes is particularly dangerous during pregnancy because of the risk of neonatal infection. This is discussed in four situations of genital herpes associated with pregnancy. Choosing the most appropriate method of delivery, i.e. carrying the least risk of transmission from mother to baby, is based on our knowledge of the natural history of genital herpes infection, the risk to the newborn (estimated from epidemiological studies), and, lastly, the possible preventive measures available.

Cesarean Section↗

[Sports and maxillofacial injuries: etiological and clinical aspects apropos of 46 cases. Preventive measures].

Maxillofacial injuries due to sporting activities represent approximately 10% of all cases of injury admitted to the University Hospital Center, Lyon, France, and more than half of these occur in football or rugby players. The causes of these accidents (blows against another player, the ground, the field equipment or the game accessories) are discussed. Lesions are generally simple in young, fit adults and results of surgical treatment satisfactory, apart from the rare cases of facial disruption. Preventive measures include examination for aptitude for sporting activities, adequate referring of games and the wearing of helmets, masks and inter-maxillary protective bars.

Adult↗

[Mechanism and prevention measures of gene silencing].

With the widely application of transgene technology in the fields of high-level biologies, more and more attention was payed to gene silence. Gene silence can take place at the phase of transcription and post-transcription. With the results of methylation, repeated copies and homologous sequence of inner genes, trans-gene are silenced. There are many kinds of mechanisms of gene silencing and here, the mechanisms explaining the gene silence and some prevention measures were summarized in this paper.

DNA Methylation↗

Outbreak of neonatal Klebsiella septicaemia at the University College Hospital, Ibadan, Nigeria. Appraisal of predisposing factors and preventive measures.

The report concerns an outbreak of neonatal Klebsiella septicaemia at the University College Hospital, Ibadan, Nigeria, between October and November 1991. Mortality, 35.7%, was higher in the preterm babies than in the term babies (p < 0.05). The important predisposing factors to infection identified were birth asphyxia, necessitating active resuscitation, prematurity, prolonged rupture of the membranes and maternal intrapartum pyrexia. The Klebsiella species isolated from the babies and the hospital environment during the outbreak were of the multiple drug resistant type. Preventive measures and the need for a continual bacteriological surveillance are highlighted.

Bacteremia↗

Health problems due to long working hours in Japan: working hours, workers' compensation (Karoshi), and preventive measures.

Late in the 1970s, serious social concern over health problems due to long working hours has arisen in Japan. This report briefly summarizes the Japanese circumstances about long working hours and what the Government has achieved so far. The national statistics show that more than 6 million people worked for 60 h or more per week during years 2000 and 2004. Approximately three hundred cases of brain and heart diseases were recognized as labour accidents resulting from overwork (Karoshi) by the Ministry of Health, Labour and Welfare (MHLW) between 2002 and 2005. Consequently, the MHLW has been working to establish a more appropriate compensation system for Karoshi, as well as preventive measures for overwork related health problems. In 2001, the MHLW set the standards for clearly recognizing Karoshi in association with the amount of overtime working hours. These standards were based on the results of a literature review and medical examinations indicating a relationship between overwork and brain and heart diseases. In 2002, the MHLW launched the program for the prevention of health impairment due to overwork, and in 2005 the health guidance through an interview by a doctor for overworked workers has been enacted as law. Long working hours are controversial issues because of conflicts between health, safety, work-life balance, and productivity. It is obvious that we need to continue research regarding the impact on worker health and the management of long working hours.

Accidents, Occupational↗

The epidemiological evidence concerning intake of mutagenic activity from the fried surface and the risk of cancer cannot justify preventive measures.

In the fried meat surface layer (the meat crust) mutagenic heterocyclic amines are formed during cooking. A human cancer risk is conceivable after intake of such mutagenic activity. We investigated the current literature mentioning fried foods, and six studies of colorectal cancer, three of stomach cancer and one each of cancer of the breast, lower urinary tract and pancreas are included. None of the reports tried to assess directly the intake of mutagenic activity from the fried surface. One indirect measure of mutagenic activity is to look at the browning of the meat surface; two investigations are available for this variable. The content of mutagenic activity in the surface may vary with the 'doneness' of meat and two studies consider this variable. Another indirect measure is to compare results from meat irrespective of cooking methods (ie, comparing meat not fried with fried meat or fried foods). There are several validity problems in the reviewed studies. Major potential sources of bias include, quite apart from misclassification of mutagenic activity, possible confounding factors from meat per se and fat. The epidemiological evidence in the field is sparse and cannot justify preventive measures.

Colonic Neoplasms↗

Preventive measures for microflora and mycotoxin production in foodstuffs.

The conservation of foodstuffs by chemical or physical methods is now practiced on a wide scale. Certain procedures (drying, use of pesticides) are well proved and are used on an industrial scale, although in certain situations they are not without risk to human health. New techniques (controlled atmospheres, irradiation, fumigation) are in use and will undoubtedly see further development for conservation of seeds and cereals in both industrialized and non-industrialized countries. In the latter case, the use of cost-effective fumigants may be of particular value. Preventive measures for the control of molds in foodstuffs are discussed in this report.

Food Contamination↗

[Improving the sanitary and epidemiologic surveillance system is a necessary condition for enhancing the efficiency of preventive measures against parasitic diseases].

The paper presents a pattern of the improved sanitary and epidemiological surveillance system against parasitic diseases in Russia at the present stage. A great deal of species of causative agents of parasitic diseases, a great variety of ways and factors of their transmission show that there is a need for its further optimization by taking into account local, natural, climatic and social conditions of the population's life and activities and paying a particular attention to the system's key point, namely to the evaluation of the risk of infection, which is the basis of planning preventive measures against parasitic diseases.

Environmental Monitoring↗

[Lumbar syndrome as an occupational disease and preventive measures].

A medical expert opinion concerning lumbar syndrome as an occupational disease should only be made if the condition of adequate job-related stress exists. There are no difficulties to diagnose the chronic lumbar syndrome. However, the assessment of the connection in cause may be difficult because of the lack of strong distinctive criterias between job-related degenerative signs and those due to fate. Guidelines for decision-making are demonstrated. The degree of disability due to occupational disease considers the part of the labour market which is closed to the insured person out of functional aspects and preventive reasons. In order to avoid job-related lumbar syndromes, preventive measures at the working place should be the common aim of all involved disciplines in collaboration with the technical service.

Expert Testimony↗

[Scalds in children caused by water from toppled electrical kettles. Mechanisms, costs and preventive measures].

Since 1988 a new type of burns in children has been recorded at the Burns Centre at Hvidovre Hospital in Copenhagen, being scalds caused by water from toppled electrical kettles (el-kettles). The children with el-kettle scalds were younger and their injuries more severe than those of children whose scalds had other causes. During the six year period 1988 to 1993, a total of 29 children (0-3 years) have been admitted with scalds caused by el-kettles, 15 children alone in 1993. The costs for treatment have been more than 3 million Danish kroner, 1.8 million DKK alone in 1993. From 1993 preventive measures were taken to reduce the number of this type of scalds. Since the number of households with el-kettles in Denmark is on the increase, an increasing number of toddlers with severe scalds could be anticipated. However, a fall in the number of children admitted was registered in 1994 (four children) and 1995 (six children).

Accidents, Home↗