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Psychometric validity and clinical usefulness of the Vineland Adaptive Behavior Scales and the AAMD Adaptive Behavior Scale for an autistic sample.

Two prominent assessment measures of adaptive behavior were compared and evaluated in terms of their psychometric properties and their clinical usefulness for autistic children and adolescents. The AAMD Adaptive Behavior Scale-School Edition (Lambert & Windmiller, 1981) and the Vineland Adapative Behavior Scales (Sparrow, Balla, & Cicchetti, 1984) were compared in 15 autistic persons aged 8 to 18. Correlations between the two instruments revealed good concurrent validity. The psychometric properties of the tests were similar to those found in samples of mentally retarded persons. The use of adaptive behavior measures for autistic children and adolescents is encouraged. Clinical advantages and disadvantages of the two tests are discussed.

Activities of Daily Living↗

The Vineland Adaptive Behavior Scale in a sample of normal French Children: a research note.

The Vineland Adaptive Behavior scale (survey form) was used in a sample of 151 normal children under age 18. Standardized mean scores of French children were comparable to those of the American normative sample. From the age of 6 onwards, French children scored consistently lower in the Daily Living Skills domain though the magnitude of this difference remained moderate. While the overall findings support the cross-cultural stability of the psychometric properties of this instrument, attention is drawn to potential problems in the use of the Vineland scales, with special reference to autistic samples.

Activities of Daily Living↗

Polychlorinated biphenyls in mother milk and adapted cow's milk.

In the present study, 50 samples of mother milk and 20 samples of adapted cow's milk produced for bottle feeding supplied from the lactarium of the Pediatric Hospital were examined for presence of 6 indicator congeners of polychlorinated biphenyls (IUPAC No. 28, 52, 101, 138, 153, and 180). Congeners No. 138, 153, and 180 were predominant in all samples, the highest mean as well as the maximum level was found for No. 138 for both type of samples. The average daily intake based on the sum of indicator congeners was found to be 2.56 micrograms. (kgb.w..day)-1 for mother milk, and 0.85 microgram.(kgb.w..day)-1 for adapted cow's milk.

Adult↗

Processing of ND NMR spectra sampled in polar coordinates: a simple Fourier transform instead of a reconstruction.

In order to reduce the acquisition time of multidimensional NMR spectra of biological macromolecules, projected spectra (or in other words, spectra sampled in polar coordinates) can be used. Their standard processing involves a regular FFT of the projections followed by a reconstruction, i.e. a non-linear process. In this communication, we show that a 2D discrete Fourier transform can be implemented in polar coordinates to obtain directly a frequency domain spectrum. Aliasing due to local violations of the Nyquist sampling theorem gives rise to base line ridges but the peak line-shapes are not distorted as in most reconstruction methods. The sampling scheme is not linear and the data points in the time domain should thus be weighted accordingly in the polar FT; however, artifacts can be reduced by additional data weighting of the undersampled regions. This processing does not require any parameter tuning and is straightforward to use. The algorithm written for polar sampling can be adapted to any sampling scheme and will permit to investigate better compromises in terms of experimental time and lack of artifacts.

Algorithms↗

Disability parameters, chronic strain, and adaptation of physically handicapped children and their mothers.

Investigated the contribution of disability parameters and chronic disability-related strain to the adaptation of 50 congenitally physically handicapped 6- to 11-year-old children and their mothers. Multiple dimensions of adaptation, disability status, and chronic disability-related strain were assessed with a variety of procedures. The mothers reported their children and themselves to display significantly worse adaptation than expected for a general sample. The adaptation of these children and their mothers, however, was not significantly related to the children's disability status nor the chronic strain thereto related. An exception was that the children's social functioning could be significantly explained by both of these factors. The inability to explain most dimensions of adaptation in the children and their mothers as it relates to the conceptual model guiding this research is discussed.

Adaptation, Psychological↗

Sharpen&Bend: recovering curved sharp edges in triangle meshes produced by feature-insensitive sampling.

Various acquisition, analysis, visualization, and compression approaches sample surfaces of 3D shapes in a uniform fashion without any attempt to align the samples with sharp edges or to adapt the sampling density to the surface curvature. Consequently, triangle meshes that interpolate these samples usually chamfer sharp features and exhibit a relatively large error in their vicinity. We present two new filters that improve the quality of these resampled models. EdgeSharpener restores the sharp edges by splitting the chamfer edges and forcing the new vertices to lie on intersections of planes extending the smooth surfaces incident upon these chamfers. Bender refines the resulting triangle mesh using an interpolating subdivision scheme that preserves the sharpness of the recovered sharp edges while bending their polyline approximations into smooth curves. A combined Sharpen&Bend postprocessing significantly reduces the error produced by feature-insensitive sampling processes. For example, we have observed that the mean-squared distortion introduced by the SwingWrapper remeshing-based compressor can often be reduced by 80 percent executing EdgeSharpener alone after decompression. For models with curved regions, this error may be further reduced by an additional 60 percent if we follow the EdgeSharpening phase by Bender.

Algorithms↗

Analysis of rabbit doe longevity using a semiparametric log-Normal animal frailty model with time-dependent covariates.

Data on doe longevity in a rabbit population were analysed using a semiparametric log-Normal animal frailty model. Longevity was defined as the time from the first positive pregnancy test to death or culling due to pathological problems. Does culled for other reasons had right censored records of longevity. The model included time dependent covariates associated with year by season, the interaction between physiological state and the number of young born alive, and between order of positive pregnancy test and physiological state. The model also included an additive genetic effect and a residual in log frailty. Properties of marginal posterior distributions of specific parameters were inferred from a full Bayesian analysis using Gibbs sampling. All of the fully conditional posterior distributions defining a Gibbs sampler were easy to sample from, either directly or using adaptive rejection sampling. The marginal posterior mean estimates of the additive genetic variance and of the residual variance in log frailty were 0.247 and 0.690.

Animals↗

The Scottish First Episode Schizophrenia Study V. One-year follow-up. The Scottish Schizophrenia Research Group.

Of 49 schizophrenic patients followed up 12 months after their first admission to hospital, only about 45% had experienced no relapse and had no schizophrenic symptoms; a poorer outcome was more often found in Feighner positive than Feighner negative schizophrenic patients. The patients' overall level of unemployment had more than doubled to 51%. In patients whose acute episodes responded to treatment, pimozide taken once weekly as maintenance therapy was as effective as intramuscular flupenthixol decanoate, but tardive dyskinesia appeared in two patients receiving weekly pimozide; the repeat psychometric assessment at 12 months found modest improvements, i.e. no evidence of intellectual decline, in Matrices, Block Design, and Digit Copying tests. Forty per cent of relatives still showed significant psychological distress, which correlated with patients' schizophrenic symptoms, and the relatives' social functioning remained poorer than that of a normal community sample.

Adaptation, Psychological↗

A new generation of serum anti-HIV antibody immunocapture assay for saliva testing.

BACKGROUND: Epidemiological studies need easier tools to evaluate HIV prevalence, particularly in high-risk groups under difficult field conditions. Testing saliva antibody with accurate immunoassay could serve as an alternative to serum testing. OBJECTIVES: To evaluate performances on saliva of a novel commercially available assay for anti-HIV antibody. STUDY DESIGN: Samples of saliva from 530 patients were tested for the presence of HIV antibodies with a third generation commercially available serum-screening kit and the use of a sample diluent adapted to saliva. RESULTS: Compared with serum sampling the sensitivity and specificity of oral sampling were respectively, 100 and 99.8%. CONCLUSION: The ICE HIV-1.0.2 assay used on saliva could be an efficient and non-invasive epidemiological tool for HIV testing.

Adult↗

Further psychometric evaluation and revision of the Mayo-Portland Adaptability Inventory in a national sample.

OBJECTIVES: To evaluate the internal consistency of the Mayo-Portland Adaptability Inventory (MPAI), further refine the instrument, and provide reference data based on a large, geographically diverse sample of persons with acquired brain injury (ABI). SUBJECTS: 386 persons, most with moderate to severe ABI. SETTINGS: Outpatient, community-based, and residential rehabilitation facilities for persons with ABI located in the United States: West, Midwest, and Southeast. METHODS: Rasch, item cluster, principal components, and traditional psychometric analyses for internal consistency of MPAI data and subscales. RESULTS: With rescoring of rating scales for 4 items, a 29-item version of the MPAI showed satisfactory internal consistency by Rasch (Person Reliability=.88; Item Reliability=.99) and traditional psychometric indicators (Cronbach's alpha=.89). Three rationally derived subscales for Ability, Activity, and Participation demonstrated psychometric properties that were equivalent to subscales derived empirically through item cluster and factor analyses. For the 3 subscales, Person Reliability ranged from.78 to.79; Item Reliability, from.98 to.99; and Cronbach's alpha, from.76 to.83. Subscales correlated moderately (Pearson r =.49-.65) with each other and strongly with the overall scale (Pearson r=.82-.86). CONCLUSIONS: Outcome after ABI is represented by the unitary dimension described by the MPAI. MPAI subscales further define regions of this dimension that may be useful for evaluation of clinical cases and program evaluation.

Adaptation, Psychological↗

The many adaptations of bone.

Studies concerned with the "adaptations" in bones usually deal with modelling taking place during the individual's lifetime. However, many adaptations are produced over evolutionary time. This survey samples some adaptations of bone that may occur over both length scales, and tries to show whether short- or long-term adaptation is important. (a) Woven and lamellar bone. Woven bone is less mechanically competent than lamellar bone but is frequently found in bones that grow quickly. (b) Stress concentrations in bone. Bone is full of cavities that potentially may act as stress concentrators. Usually these cavities are oriented to minimise their stress-concentrating effect. Furthermore, the "flow" of lamellae round the cavities will still further reduce their stress-concentrating effect, but the elastic anisotropy of bone will, contrarily, tend to enhance it in normal loading situations. (c) Stiffness versus toughness. The mineral content of bone is the main determinant of differences in mechanical properties. Different bones have different mineral contents that optimise the mix of stiffness and toughness needed. (d) Synergy of whole bone architecture and material properties. As bone material properties change during growth the architecture of the whole bone is modified concurrently, to produce an optimum mechanical behaviour of the whole bone. (e) Secondary remodelling. The formation of secondary osteones in general weakens bone. Various suggestions that have been put forward to account for secondary remodelling: enabling mineral homeostasis; removing dead bone; changing the grain of the bone; taking out microcracks. (f) The hollowness of bones. It is shown how the degree of hollowness is adapted to the life of the animal.

Adaptation, Physiological↗

Parental perceptions of infant vulnerability in a preterm sample: prediction from maternal adaptation to parenthood during the neonatal period.

The present longitudinal study of African-American mothers of preterm infants tested the hypothesis that the quality of maternal adaptation to parenthood before infant discharge from the hospital is predictive of maternal perceptions of infant vulnerability later in the infant's first year. As hypothesized, perceptions of infant vulnerability at 3 to 4 months of infant corrected age were predicted by two theoretically relevant measures of maternal adaptation in the neonatal period: mothers' perceptions of their neonates as lethargic and unresponsive to mothers' bids and by low maternal self-efficacy beliefs about feeding the infant. Neonatally obtained maternal self-inefficacy beliefs about their ability to feed the infant in particular proved to be quite robust in predicting mothers' later perceptions of infant vulnerability. Findings collectively suggest that careful attention to the manner in which mothers of preterm infants adapt to parenthood, even before infant hospital discharge, can help clinicians identify mothers at particularly high risk of developing perceptions of infant vulnerability later in the infant's first year. Implications for intervention are discussed.

Adaptation, Psychological↗

Wang-Landau sampling with self-adaptive range.

We report a self-adapting version of the Wang-Landau algorithm that is ideally suited for application to systems with a complicated structure of the density of states. Applications include determination of two-dimensional densities of states and high-precision numerical integration of sharply peaked functions on multidimensional integration domains.

Journal Article↗

The adaptation of an experimental sampling procedure for application in naturalistic psychiatric nursing research settings.

External constraints on random sampling remains a constant challenge to nurse researchers seeking control over patient recruitment when investigating the outcome of nursing treatments. Traditional non-random sampling strategies employed in naturalistic clinical settings are prone to extraneous variables that frequently compromise the internal validity of the research design and confidence in the results. This paper explores the value of the Buglass scale and minimization in the context of a quasi-experimental research study to examine the management of deliberate self-harm by community psychiatric nurses. Discussion centres on their scope for control of extraneous variables without sacrificing the naturalistic setting within which community psychiatric nurses operate. A worked example illustrates the sampling procedure for minimizing differences between subjects assigned to a treatment and comparison group.

Adolescent↗

Neurobehavioral factors associated with referral for learning problems in a community sample: evidence for an adaptational model for learning disorders.

We evaluated community general education (CGE; n = 178), community special education (CSE; n = 30) and hospital-referred (HR, n = 145) children (ages 7-6 to 11-11) prospectively over a 2-year period. During this period, 17 CGE children were referred for evaluation (community referred; CR). Prior to referral, CR children performed more poorly than community-nonreferred (CNR) children on cognitive ability, academic achievement, attention problems, and information processing. CR group performance was equivalent to that of CSE and HR groups, but HR children showed poorer academic achievement. Referred children performed more poorly on all measures than nonreferred, whether they met formal diagnostic criteria for a learning disorder or not. Learning disorders may be better conceptualized as a context-dependent problem of functional adaptation than as a disability analogous to physical disabilities, raising questions about the validity of using psychometric test scores as the criterion for identification.

Achievement↗

Declarative memory retention and emotional stimuli. A study of an Italian sample.

Psychological and pharmacological studies in humans suggest that emotional arousal enhances long-term memory. In this paper we used, in an Italian sample, an adaptation of a paradigm previously utilized in American samples to study the relationship between emotion and long-term memory. Seventy-two healthy adults from different educational backgrounds were randomly assigned either to a neutral group or to an emotional arousal group and then told a short story, presented audio-visually. In both groups, the slides shown and the slide sequence were the same, and the images were accompanied by a narrative. The two versions of the story differed primarily in their emotional content. Shortly after viewing the slide presentation, the participants were asked to rate the emotionality of the narrative, and ten days later were submitted to a retention test. The emotionally-arousing version of the story was rated as more emotional than the neutral one. Compared with the members of the neutral group, the subjects in the arousal group recalled a significantly higher number of elements from the story. There was no overall difference between the two groups in performance on the recognition memory test. These results confirm that the emotional content of stimuli enhances long-term declarative memory of those stimuli, and indicate the possible usefulness of applying the paradigm utilized in this study to different clinical samples from various cultural backgrounds.

Adolescent↗