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At least 163 records · Page 9Linked to original sources

Vaginourethroplasty for treatment of urethral obstruction in the bitch.

Vaginourethroplasty was performed in six bitches with infiltrative, obstructive urethral disease. The initial clinical signs included dysuria, hematuria, pollakiuria, and stranguria. Diagnosis was based on the clinical signs, plain radiography and contrast vagino-urethrogram examination, and urethral biopsy. Five dogs were diagnosed as having urethral neoplasia; the sixth dog had granulomatous urethritis. In all six dogs, up to 50% of the urethra and the urethral tubercle were resected to ensure adequate surgical margins. One dog was euthanatized 4 months after surgery for recurrence of a transitional cell carcinoma at the surgical site. Long-term resolution of the problem (minimum of 12 months) was achieved in the other five dogs. The frequency of serious complications, including urinary incontinence and ascending lower urinary tract infections, was low.

Animals↗

Two chondrosarcomas in the urethra of a German shepherd dog.

An eight-year-old, male castrated German shepherd dog was presented with signs consistent with urinary obstruction. Cystoscopy and contrast radiography showed two distinct urethral masses. Penile amputation and perineal urethrostomy were performed to alleviate the clinical signs. Histopathology of the masses revealed two low-grade chondrosarcomas. At the time of writing, 18 months after surgery, the dog remained disease free.

Animals↗

Upper tract transitional cell carcinoma following cystectomy for bladder cancer.

PURPOSE: We assessed the incidence of upper urinary tract tumors (UUTTs) after cystectomy for invasive or superficial transitional cell carcinoma (TCC) of the bladder. The risk factors, patients' characteristics and evolution of those who developed UUTTs are analyzed. MATERIALS AND METHODS: From August 1980 to February 1994, 568 radical cystectomies were performed for TCC of the bladder: in 469 instances (82.5%) due to invasive tumor (T2-T4), and in 99 cases (17.5%) for superficial tumor (Ta, T1, Tis). All patients were followed for at least 5 years or until death. A retrospective study of patients who developed UUTTs has been performed. A revision of bladder tumor and UUTT characteristics, and the intervals between both is also evaluated. RESULTS: 26 patients (4.5%) developed UUTTs: 11 of the 99 patients cystectomized for superficial TCCs (11.1%); 6 of the 392 patients with primary invasive TCC (1.5%), and 9 of the 77 (11.6%) patients with invasive tumors and a prior history of superficial TCC. The interval to the development of UUTT was higher after cystectomy for superficial tumor. TCCs of the bladder that subsequently developed UUTTs were high grade in 84%, multifocal in 80%, or had carcinoma in situ in 65%, tumor in the prostatic urethra in 52%, and involvement of the distal ureter in 57%. Twenty-two UUTTs (84%) were located in the calyces or the renal pelvis, 3 were bilateral (11.5%), 14 multiple (58%) and 4 superficial (16%). With a median follow-up time of 18 (range 3-103) months, 14 patients (53.8%) died of tumor, 2 were alive with disease, 2 were lost for follow-up, and 8 (30%) were alive and free of disease. CONCLUSIONS: We found that patients cystectomized for superficial or invasive TCC with a prior history of superficial TCC have a higher incidence of UUTTs. These cases require follow-up with annual urography or loopography.

Aged↗

Transitional cell carcinoma of the fossa navicularis in a man with preexisting adenocarcinoma of the prostate.

In this report we present a patient with a history of prostatic adenocarcinoma who was found to have a low-grade/low-stage transitional cell carcinoma of the fossa navicularis. The patient underwent transurethral resection and at approximately 2 years of follow-up he has no evidence of tumor recurrence. Very limited follow-up data exist on which to base management decisions, and this report lends support to the use of transurethral resection alone as a means to treat low-grade/low-stage lesions.

Adenocarcinoma↗

Signet-ring cell carcinoma of the bladder and the prostate. Report of 4 cases.

During a 9-year period in our clinic 4 patients were seen with signet-ring cell carcinoma. 2 patients had primary signet-ring cell carcinoma of the bladder, 1 of the prostate. In the 4th case the tumor was located near the penoscrotal angle of the urethra. These cases are reviewed and their main characteristics, mentioned in the literature, are discussed briefly.

Adenocarcinoma, Mucinous↗

Urethral narrowing due to ectopic prostatic tissue in the bulbar urethra.

Ectopic prostatic tissue in the bulbar urethra is a rare disorder. A case of urethral narrowing due to such tissue is presented. The tissue specimen from the urethral narrowing was positively stained immunohistochemically by the prostatic specific antigen. Urethrocystographic findings are also discussed.

Choristoma↗

Urethral tuberculosis.

Tuberculous affection of the urethra is very rare. Herein we report 2 cases of urethral tuberculosis. One in a young married female who had isolated urethral involvement presenting as urethral caruncle and the second in a young male with urethral stricture complicated by fistulae and abscess in association with renal tuberculosis. The relevant literature is briefly reviewed.

Adult↗

Squamous cell carcinoma of perineal urethrostomy.

Urethral malignancies are rare while only few cases of urethral carcinoma following urethroplasty have been reported in the literature. We present a case of squamous cell carcinoma at perineal urethrostomy.

Carcinoma, Squamous Cell↗

Early 'invasive' malignant melanoma of the glans penis and the male urethra. Report of a case and review of the literature.

A 40-year-old male with early 'invasive' malignant melanoma of the glans penis and meatus urethrae externus is presented. Early stages of primary melanoma of the glans penis and the male urethra are distinctly rare and are often clinically indistinguishable from penile lentigo, melanosis and melanocytic nevus on the genitalia. In order to avoid large and useless surgery on such a delicate location we propose a punch biopsy with subsequent histological examination prior to definitive surgical procedure. Whereas malignant melanoma of the penis with a thick Breslow index is treated with extended surgical management, only local excision of the tumor without groin dissection was performed in our patient.

Adult↗

An unusual cause of urethral stricture: urethral lymphangioma.

We report an unusual case of urethral narrowing which is caused by lymphangioma. The natural history of lymphangioma of the urethra is described. To our knowledge, lymphangioma of the urethra as a cause of urethral stricture has not been reported to date. Although lymphangioma of the urethra is a benign disease, it must be included among the causes of urethral stricture.

Adult↗

Management of intrameatal warts in men.

The case notes of 1080 men with genital warts were analysed retrospectively over a 30-month period. One hundred and forty patients were identified with intrameatal warts and an audit of their treatment is discussed. When electrocautery and cryotherapy were compared the former produced a more rapid resolution of the lesions. Cystourethroscopy was performed on 16 patients with intrameatal warts. No patient had involvement beyond the distal 3 cm of the urethra. Data on concurrent sexually transmitted diseases, population characteristics and pattern of referral are presented and compared to previously reported studies.

Adolescent↗