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Quantitative examination of taste deficiency due to radiation therapy.

A study was carried out with a Rion TR-03 type electro-gustometer for subjective and quantitative expression of the degree of taste deficiency due to radiation therapy and the effects of treatment. The changes of the electro-gustometric threshold due to irradiation were examined in patients who were divided into three groups: those receiving irradiation of the whole oral cavity, those receiving irradiation of the posterior tongue and the soft palate and those receiving irradiation of the gustatory nervous system. In the group receiving irradiation of the whole oral cavity, the threshold showed a tendency to increase when receiving 10 Gy/5 days, and the threshold became unmeasurable when more than 40 Gy/26 days was given. In the group receiving irradiation of the posterior tongue and the soft palate, almost no change of the threshold in the anterior was observed in spite of increasing irradiation doses. In the group receiving irradiation of the gustatory nervous system, the threshold in the intact hemicephalus did not changed even after irradiation, but a change was found on the pathological side. Based on these results, the authors originated a complication scoring system and a treatment scoring system both of which are divided into five stages. An electro-gustometric examination is used in order to provide effective treatment with a preserving function something which has been strongly desired for radiation therapy of cancer.

Brain Neoplasms

[Methodological critical studies of taste using chemical stimuli].

Two methods of the chemical examination of taste were compared in view of its practicability. The "Three-Choice-Technique" is most profitable for the clinical use. It is carried out easily and quickly, and the results permit a sufficient and exact estimation of the taste sensitivity. The "Assorting-Technique" seems to be less useful. It provides lower thresholds, but the expense is higher. The Three-Choice-Technique, the special concentration sequences and the ascertained normal threshold for the four basic taste qualities enable a better registration of taste disturbances, at which side differences are of no consequence.

Adolescent

Taste thresholds of individuals with diabetes mellitus and of control subjects.

This study was designed to determine whether any difference in taste acuity exists between individuals with a diagnosis of Type I diabetes mellitus and control subjects. Detection and recognition thresholds were evaluated for sodium chloride, sucrose, citric acid, and quinine sulfate. The results indicate that diabetes or age can decrease an individual's ability to detect and recognize sweet, salty, and bitter solutions. Decreased taste acuity in individuals with diabetes may be an important factor in the perception of food.

Adolescent

[Taste changes in patients with AL amyloidosis. Preliminary studies].

Taste acuity in 20 subjects affected by AL amyloidosis without oral complications was investigated by threshold determination. Sixteen cases did not recognize one or more fundamental tastes. Sour was the most frequently lost taste, as it was not recognized by 10 out of 20 cases. So, sensorial neuropathy, altering taste generation and/or transmission, seems frequently associated to AL amyloidosis. Further researches will show if taste losses realize typical symptomatic features in this disease.

Adult

Distribution of taste thresholds for phenylthiocarbamide among different age groups in Turkey.

The relation between age and taste threshold in populations living both in Istanbul and Resadiye, a town located in eastern part of Turkey, was investigated. In Turkey the nontaster/taster ratio has been found lower than in the other countries of Europe and Asia (3 ,4 ,8 ,9). With aging the taste sensitivity of tasters does diminish. However, the differences in the taste threshold levels of nontasters, in different age groups, have been found as being statistically not significant.

Adolescent

Medical management of taste and smell disorders.

Chemosensory dysfunction is most often secondary to one of only a few causes: nasal/sinus disease, viral infection, toxic chemical exposure, head trauma, as well as medication-related and idiopathic conditions. Medication-related disorders are corrected by discontinuance of the causative medicine. Our experiences have also shown that only dysfunctions of smell caused by disorders of the nose and/or sinuses are amendable to therapy.

Adrenal Cortex Hormones