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At least 163 records · Page 9Linked to original sources
PubMed2002

The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel.

Mechanosensory transduction in touch receptor neurons is believed to be mediated by DEG/ENaC (degenerin/epithelial Na+ channel) proteins in nematodes and mammals. In the nematode Caenorhabditis elegans, gain-of-function mutations in the degenerin genes mec-4 and mec-10 (denoted mec-4(d) and mec-10(d), respectively) cause degeneration of the touch cells. This phenotype is completely suppressed by mutation in a third gene, mec-6 (refs 3, 4), that is needed for touch sensitivity. This last gene is also required for the function of other degenerins. Here we show that mec-6 encodes a single-pass membrane-spanning protein with limited similarity to paraoxonases, which are implicated in human coronary heart disease. This gene is expressed in muscle cells and in many neurons, including the six touch receptor neurons. MEC-6 increases amiloride-sensitive Na+ currents produced by MEC-4(d)/MEC-10(d) by approximately 30-fold, and functions synergistically with MEC-2 (a stomatin-like protein that regulates MEC-4(d)/MEC-10(d) channel activity) to increase the currents by 200-fold. MEC-6 physically interacts with all three channel proteins. In vivo, MEC-6 co-localizes with MEC-4, and is required for punctate MEC-4 expression along touch-neuron processes. We propose that MEC-6 is a part of the degenerin channel complex that may mediate mechanotransduction in touch cells.

Animals↗
PubMed2003

The nature of touch therapy related to Ki: practitioners' perspective.

Touch therapy related to Ki, a type of healing touch, has been regarded as one of the distinct therapeutic modalities in traditional oriental medicine. The present study attempted to develop a substantive theory about helping patients using touch therapy related to Ki, by exploring the views of practitioners who are using this therapeutic modality within the context of the Korean society. A grounded theory approach was applied during the collection and analyses of data. The core category, main categories and trajectory of helping patients during the use of touch therapy related to Ki was delineated. Helping patients while using touch therapy related to Ki was found to be a dynamic process with each participant actively engaged in increasing the activating, potential power of the human being. These findings have value in understanding the embedded meaning of the healing process through touch therapy within the context of Ki.

Adult↗
PubMed1998

Age, relationship, and touch initiation.

Gender asymmetry in touch in U.S. populations is related to the age of the participants in some studies and to the relationships between the participants in others. In the present study, researchers observed dyads in public settings in the United States frequented by couples and recorded the occurrence of touch, the touch initiator, and the body areas touched. The researchers then approached the couples and asked them to complete questionnaires indicating their ages, their relationship, and their level of agreement on major issues. Age and relationship were predictive of the gender of touch initiators. Although levels of agreement were less predictive of touch initiation, the women indicated higher levels of agreement than the men did. The results were generally consistent with a model of sex differences in reproductive strategies.

Adolescent↗
PubMed1999

The effect of waitresses' touch on alcohol consumption in dyads.

A total of 96 men and 48 women participated in a study on the effect of touch in the natural setting of public taverns in the United States. Participants in the same-gender (men-men) or mixed-gender dyads were either touched or not touched by waitress confederates. Regardless of dyad type, participants who were touched consumed more alcohol than participants who were not touched. Men in the mixed-gender dyads consumed more alcohol when the women was touched. Same-gender (men-men) dyads aggregately consumed more alcohol than mixed-gender dyads. The results are interpreted in terms of the environmental cues and the dynamics of the group.

Adult↗
PubMed1995

Transcending the latex barrier: the therapeutics of comfort touch in patients with acquired immunodeficiency syndrome.

Comfort touch has a positive impact on patient outcomes. When using Latex gloves, nurses often overlook the importance of skin-to-skin contact in effective comfort touch. Comfort touch is especially essential in vulnerable populations that are already experiencing several physical and emotional losses. Nurses' attitudes and fears may be a contributing factor to comfort touch not always being provided in caring for patients with acquired immunodeficiency syndrome (AIDS). The article discusses the therapeutics of comfort touch and explores the issues surrounding the absence of comfort touch in nursing interactions in patients with AIDS. Suggestions are made for nursing practice, education, and research.

Attitude of Health Personnel↗
PubMed1980

Heart rate response to touch.

The effect of tactile stimulation on heart rate (HR) in humans was investigated under three conditions: 1) Experimenter outside of room in which subject is sitting; 2) experimenter in the room with the subject; 3) experimenter in the room while touching the subject's right wrist. Nonsignificant increases in HR were observed when the experimenter entered the room (X = 0.64 beats per minute (bpm)). Conversely, large decreases occurred when the experimenter placed his hand on the subject's wrist (X = 9.16 bpm, p is less than 0.05). To determine if tactile stimulation alone accounts for these differences three comparisons were made in a second experiment: 1) Experimenter out of test room, subject touches own wrist; 2) experimenter in room standing near subject; 3) experimenter touching subject's wrist. Subjects showed slightly elevated HR during the self-touch condition (X = 1.26 bpm, not significant). Although no change was noted with the experimenter standing beside the subject, there were decreases, as in Experiment I, when the experimenter touched the subject's wrist (X = 1.75 bpm, p is less than 0.05). These results suggest that the observed decreases in HR were contingent upon another person's touch. While self-tactile stimulation produced a slight increase in HR, tactile stimulation by another caused bradycardia.

Adult↗
PubMed2001

Inhibition of touch cell fate by egl-44 and egl-46 in C. elegans.

In wild-type Caenorhabditis elegans, six cells develop as receptors for gentle touch. In egl-44 and egl-46 mutants, two other neurons, the FLP cells, express touch receptor-like features. egl-44 and egl-46 also affect the differentiation of other neurons including the HSN neurons, two cells needed for egg laying. egl-44 encodes a member of the transcription enhancer factor family. The product of the egl-46 gene, two Drosophila proteins, and two proteins in human and mice define a new family of zinc finger proteins. Both egl-44 and egl-46 are expressed in FLP and HSN neurons (and other cells); expression of egl-46 is dependent on egl-44 in the FLP cells but not in the HSN cells. Wild-type touch cells express egl-46 but not egl-44. Moreover, ectopic expression of egl-44 in the touch cells prevents touch cell differentiation in an egl-46-dependent manner. The sequences of these genes and their nuclear location as seen with GFP fusions indicate that they repress transcription of touch cell characteristics in the FLP cells.

Alleles↗
PubMed1994

Care of the critically ill patient: the impact of stress on the use of touch in intensive therapy units.

The literature suggests that stress is a major factor for nurses personally 'disengaging' from patients who are critically ill. This research aimed to investigate if nurses in a general intensive therapy unit (ITU) disengage from their patients by using touches that are mainly task orientated, rather than caring/social touches. This study sought to establish whether there was a relationship between categories of touch deployed by nurses and the individual characteristics of the nurses. The patient's prognosis (as perceived by the nurse) was also explored in relation to the touch types used. The nurses were observed and the observations were categorized with the use of an adapted taxonomy (Estabrooks 1989). This study also sought to identify potential stressors for nurses in ITU through a semi-structured interview. The analysis of the observational data indicated that there was no significant relationship between touch type and a patient's prognosis. However, there was a significant relationship between caring/social touch and a nurse's length of service (rs = -0.54, P < 0.01). The interview data discovered that the stressors were related to the organizational pressures of the environment in which care was delivered, rather than the involvement of caring for critically ill patients. This apparent contradiction of the literature contributes a further dimension in considering the impact of management changes and organizational structures upon nurses' stress, which has further implications for the delivery of care in ITUs.

Adult↗
PubMed2000

Evidence-based practice and reviews of therapeutic touch.

PURPOSE: To present principles for accurately representing research for evidence-based practice and health care policies, and to evaluate how original research results indicated adherence to those principles in literature reviews of therapeutic touch. ORGANIZING CONSTRUCTS: Critical thinking and scientific integrity. SOURCES: Reviews of therapeutic touch literature published in nursing journals between 1994 and 1998 and the research studies cited in those reviews. METHODS: Statements made in reviews about the efficacy of therapeutic touch were compared with the results and conclusions of the research cited. General conclusions reported in reviews were evaluated against a broad range of therapeutic touch (TT) research studies, including many not cited in reviews. How accurately reviewers represented the research studies was evaluated by comparing reviewers' conclusions with those of the researchers. Findings were organized into principles to guide evidence-based reviews. FINDINGS: Literature reviews about therapeutic touch often cited only research with favorable findings. When citing studies with contradictory findings, only the favorable findings were usually mentioned. In many reviews, research cited as indicating the efficacy of therapeutic touch indicated it was ineffective. Every review examined had at least one significant mistake concerning how research studies were represented. CONCLUSIONS: Accurate presentation of original research results is needed to make evidence-based decisions and to ensure that limited healthcare resources are used effectively and safely. Evidence-based principles should be followed in reviewing therapies and practices, including alternative therapies.

Evidence-Based Medicine↗
PubMed2005

Touch and temporal behavior of grand piano actions.

This study investigated the temporal behavior of grand piano actions from different manufacturers under different touch conditions and dynamic levels. An experimental setup consisting of accelerometers and a calibrated microphone was used to capture key and hammer movements, as well as the sound signal. Five selected keys were played by pianists with two types of touch ("pressed touch" versus "struck touch") over the entire dynamic range. Discrete measurements were extracted from the accelerometer data for each of the over 2300 recorded tones (e.g., finger-key, hammer-string, and key bottom contact times, maximum hammer velocity). Travel times of the hammer (from finger-key to hammer-string) as a function of maximum hammer velocity varied clearly between the two types of touch, but only slightly between pianos. A travel time approximation used in earlier work [Goebl W., (2001). J. Acoust. Soc. Am. 110, 563-572] derived from a computer-controlled piano was verified. Constant temporal behavior over type of touch and low compression properties of the parts of the action (reflected in key bottom contact times) were hypothesized to be indicators for instrumental quality.

Equipment Design↗
PubMed2002

Cross-modal interactions between audition, touch, and vision in endogenous spatial attention: ERP evidence on preparatory states and sensory modulations.

Recent behavioral and event-related brain potential (ERP) studies have revealed cross-modal interactions in endogenous spatial attention between vision and audition, plus vision and touch. The present ERP study investigated whether these interactions reflect supramodal attentional control mechanisms, and whether similar cross-modal interactions also exist between audition and touch. Participants directed attention to the side indicated by a cue to detect infrequent auditory or tactile targets at the cued side. The relevant modality (audition or touch) was blocked. Attentional control processes were reflected in systematic ERP modulations elicited during cued shifts of attention. An anterior negativity contralateral to the cued side was followed by a contralateral positivity at posterior sites. These effects were similar whether the cue signaled which side was relevant for audition or for touch. They also resembled previously observed ERP modulations for shifts of visual attention, thus implicating supramodal mechanisms in the control of spatial attention. Following each cue, single auditory, tactile, or visual stimuli were presented at the cued or uncued side. Although stimuli in task-irrelevant modalities could be completely ignored, visual and auditory ERPs were nevertheless affected by spatial attention when touch was relevant, revealing cross-modal interactions. When audition was relevant, visual ERPs, but not tactile ERPs, were affected by spatial attention, indicating that touch can be decoupled from cross-modal attention when task-irrelevant.

Adult↗
PubMed1993

Therapeutic touch and postoperative pain: a Rogerian research study.

This article details Meehan's research study concerning the conceptualization of therapeutic touch within Rogers' science of unitary human beings and an investigation of the effects of therapeutic touch on pain experience in postoperative patients. Using a single trial, single-blind, three-group design, 108 postoperative patients were randomly assigned to receive one of the following: therapeutic touch, a placebo control intervention which mimicked therapeutic touch, or the standard intervention of a narcotic analgesic. Using a visual analogue scale, pain was measured before and one hour following intervention. The hypothesis, that therapeutic touch would significantly decrease postoperative pain compared to the placebo control intervention, was not supported. Secondary analyses suggest that therapeutic touch may decrease patients' need for analgesic medication. Implications for further research and practice are suggested.

Adult↗
PubMed2001

The use of human touch to improve the well-being of older adults. A holistic nursing intervention.

Touch and massage are viable nursing modalities that are both underutilized and understudied. This underuse of touch is especially noted in settings aimed at improving the well-being of older adults. A number of studies suggest that the appropriate use of touch by nurses has the potential to significantly improve the health status of older adults. In particular, touch can be useful with cognitively impaired, institutionalized, or hospitalized older adults. Likewise, touch can be useful for improving comfort and communication among terminally ill older adults and their loved ones. This article synthesizes some of the available literature on the subject while suggesting avenues for nursing practice and education aimed at using touch as a viable and cost-effective holistic gerontological nursing intervention.

Aged↗
PubMed2007

Repeated questions, deception, and children's true and false reports of body touch.

Four- to 7-year-olds' ability to answer repeated questions about body touch either honestly or dishonestly was examined. Children experienced a play event, during which one third of the children were touched innocuously. Two weeks later, they returned for a memory interview. Some children who had not been touched were instructed to lie during the interview and say that they had been touched. Children so instructed were consistent in maintaining the lie but performed poorly when answering repeated questions unrelated to the lie. Children who were not touched and told the truth were accurate when answering repeated questions. Of note, children who had been touched and told the truth were the most inconsistent. Results call into question the common assumption that consistency is a useful indicator of veracity in children's eyewitness accounts.

Child↗
PubMed2004

Ethical considerations in the use of nonerotic touch in psychotherapy with children.

Although touch frequently occurs in psychotherapy with children, there is little written on the ethical considerations of therapeutic touch. Because physical contact does occur, therapists must consider if, how, and when it is used, for both their clients' safety and their own. In this review, I further develop the issues suggested by Aquino and Lee (2000) in the use of nurturing touch in therapy by considering many types of touch that occur in psychotherapy with children; the possible positive role of touch; clients' perception of touch in therapy; considerations related to the therapist, the child's safety, and any history of abuse in the child's and family's background; and other practical considerations. I list guidelines.

Child↗
PubMed1978

Sex differences in the perception of touching.

Sex differences in the perception of touching were investigated by having 25 male and 25 female college students rate how likeable a touch would be under different conditions. The women produced a more favorable affect than the men when they touched, and women were perceived as liking to be touched more than men. Perception of touching in general was correlated positively with Self-esteem for men, negatively with Machiavellianism for women, and positively with Trust for women. Results were discussed in terms of traditional sex-typing of touching behavior.

Affect↗
PubMed1982

Differential reaction to touch by men and women.

An experimenter placed biofeedback electrodes on seven different locations of each subject's body. The electrodes were held in place by the experimenter for 2 min. (at each location) after which the subject rated his or her degree of comfort-relaxation. A three-factor design was employed in which the variables were touch type (hand top, forearm top and bottom, upperarm top and bottom, shoulder, back), sex of subject, and sex of experimenter. It was assumed that males would react more adversely to same-sex touch than would females when the type of touch was typical of female-female interactions (hand or arm touch) but not when the touch was typical of male-male interactions (shoulder or back touch). Results were consistent with expectations.

Adult↗
PubMed2002

Role of sex in externally motivated self-touching gestures.

Self-touching gestures can be externally induced by the verbal presentation of anxiety-inducing stimuli and the active discussion of a passage. The frequency of these self-touching gestures appears to be affected by the individual interacting with the topic, the type of discourse (listening or discussing), the type of stimulus (canaries or leeches), and the interaction between the types of discourse and stimulus. This study assessed these variables as well as the sex of the participant and the order of presentation of stimulus type, neither of which were statistically significant. Participants were read two passages, one about a topic (leeches) expected to produce anxiety and the other about a topic (canaries) not expected to do so, and asked to answer questions about the passages. The number of self-touches was counted by an observer in another room. Each participant had both types of discourse (listening and discussing) and both types of stimulus (canaries and leeches). There was no significant difference between the number of self-touches by participants with either the male or female reader. Discussion as a method of discourse was associated with a significantly greater number of self-touches than listening. The interaction between discourse type and stimulus type was also significant. The combination of the anxiety-producing stimulus and the active discourse (discussion) produced the highest average number of self-touches.

Adolescent↗