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At least 163 records · Page 9Linked to original sources

Optimal one-dimensional apodizations and shaped pupils for planet finding coronagraphy.

The realization that direct imaging of extrasolar planets could be technologically feasible within the next decade or so has inspired a great deal of recent research into high-contrast imaging. We have contributed several design ideas, all of which can be described as shaped pupil coronagraphs. We offer a complete and unified survey of one-dimensional shaped pupil designs, some of which have been published in our previous papers. We also introduce a promising new design, which we call bar-code masks. With these masks we can achieve the required contrast with a fairly large discovery zone and throughput, but most importantly they are perhaps the easiest to manufacture and might therefore stand up best to refined analyses.

Journal Article↗

Coil planet centrifugal and capillary tube centrifugal analysis of factors regulating erythrocyte osmotic fragility and deformability.

Hydrated and dehydrated red cell samples were prepared from normal human red cells using the antibiotic nystatin. Furthermore, a series of red cell samples exposed to elevated temperature (20-50 degrees C, 10 min) were prepared. The osmotic fragility and deformability of these red cells were then measured, using the coil planet centrifuge system and the capillary tube centrifugal technique, respectively. The osmotic fragility of nystatin-treated red cells decreased and the deformability increased as dehydration of red cells progressed and alternatively, hydrated cells showed increased osmotic fragility and reduced deformability. Red cells exposed to elevated temperatures up to 49 degrees C for 10 min had no changes in mean corpuscular volume or in red cell shape. Above 47 degrees C, however, spectrin extractability progressively decreased and osmotic fragility and deformability decreased. Results suggest that the osmotic fragility snd deformability of red cells are interrelated, and are controlled by the geometry of the cell, including the ratio of cell surface area to cell volume and the viscoelastic properties of the membrane.

Centrifugation↗

PLANET: a phage library analysis expert tool.

In recent years random peptide libraries displayed on filamentous phage have been widely used and new ideas and techniques are continuously developing in the field (1-5). Notwithstanding this growing interest in the technique and in its promising results, and the enormous increase in usage and scope, very little effort has been devoted to the implementation of software able to handle and analyze the growing number of phage library-derived sequences. In our laboratory, phage libraries are extensively used and peptide sequences are continuously produced, so that the need arose of creating a database (6) to collect all the experimental results in a format compatible with GCG sequence analysis packages (7). We present here the description of an XWindow-based software package named PLANET (Phage Library ANalysis Expert Tool) devoted to the maintenance and statistical analysis of the database.

Bacteriophages↗

[Osmotic fragility test of erythrocytes with a coil planet centrifuge].

The measurement of osmotic fragility of erythrocytes has been applied to the diagnosis of hemolytic diseases, studies of membrane permeability and alternations leading to destruction of erythrocytes. Almost 30 years have gone by since the coil planet centrifuge system was devised for measuring the osmotic fragility of erythrocytes. Many excellent studies by means of this centrifuge system have been published. Prominent investigations are reviewed as follows: in relation to the osmotic fragility, various liver diseases, angina pectoris, trapping the aged erythrocytes, tumor, lactic acid, unsaturated fatty acids, free cholesterol, exercise and lead exposure level were examined.

Angina Pectoris↗

Laboratory experiments in the study of the chemistry of the outer planets.

The investigation of chemical evolution of bodies in our solar system has, in the past, included observations, theoretical modeling, and laboratory simulations. Of these programs, the last one has been the most criticized due to the inherent difficulties in accurately recreating alien environments in the laboratory. Processes such as wall reactions and changes in chemistry due to difficulties in achieving realistic conditions of temperature, pressure, composition, and energy flux may yield results which are not truly representative of the systems being modeled. However, many laboratory studies have been done which have yielded data useful in planetary science. Gross simulations of atmospheric chemistry have placed constraints on the nature of complex molecules expected in planetary atmospheres. More precise studies of specific chemical processes have provided information about the sources and properties of product gases and aerosols. Determinations of basic properties such as spectral features and reaction rate constants yield data useful in the interpretation of observations and in computational modeling. Alone, and in conjunction with modeling, laboratory experiments will continue to be used to further our understanding of the outer solar system, and some experiments that need to be done are listed.

Aerosols↗