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[Results of surgical management of lunate malacia. A retrospective clinical study].

We investigated the results of 53 patients in a retrospective study after surgical treatment for Kienböck's disease. Surgery included shortening of the radius (35 cases), cancellous bone graft (four cases), pisiform transposition (two cases), Swanson prostheses (two cases), tendon interposition arthroplasty (one case), STT-arthrodesis (six cases), denervation of the wrist (one case), and wrist arthrodesis (two cases). The average follow-up was 43 months (minimum 12, maximum 84 months). Criteria for rating the results were subjective satisfaction and pain profile. Objective criteria were X-ray findings and range of motion of the hand and wrist. We paid particular attention to the economic consequences for the patients. Based on our own results and the results in the literature, we recommend bone-grafting in the early Decoulx stages I and II. In stages II and III, we recommend in cases of ulna-minus variance the shortening of the radius in combination with a bone grafting; in case of an ulna-zero variance, we have the possibility of a radius wedge osteotomy or a pisiform transposition. Stage III, especially IIIb according to Lichtman, is suitable for STT-arthrodesis. In stage IV, we recommend total wrist arthrodesis, the denervation of the wrist can be combined with all the other methods or as a salvage procedure prior to wrist arthrodesis.

Adolescent↗

Bi- and three-dimensional CT study of carpal bone motion occurring in lateral deviation.

A computed tomography (CT) study of the right wrists of 15 volunteers and of 5 anatomical preparations in neutral position, radial (15 degrees) and ulnar (30 degrees) deviation enables to tackle the qualitative analysis of carpal bone motion. The CT Scans were analyzed and reconstructed in three dimensions by means of the Philips CAMRA S100 computer program. The results show that the capitate, the metacarpals II and III and, to a lesser extent, the trapezium and the trapezoid are poorly mobile. Our study points to the role of the flexor and extensor carpi ulnaris muscles in the stability of the internal carpus, confirming that the pisiform is a sesamoid bone in the flexor carpi ulnaris tendon. A model of longitudinal functional structure of the carpus during lateral deviation, intermediate between those of Navarro and Taleisnik, is proposed.

Adult↗

Homeotic transformations and limb defects in Hox A11 mutant mice.

Hox A11 is one of the expanded set of vertebrate homeo box (Hox) genes with similarities to the Drosophila homeotic gene, Abdominal-B (Abd-B). These Abd-B-type Hox genes have been shown to be expressed in the most caudal regions of the developing vertebrate embryo and in overlapping domains within the developing limbs, suggesting that these genes play important roles in pattern formation in both appendicular and axial regions of the body. In this report whole-mount in situ hybridization in mouse embryos gave a precise description of Hox A11 gene expression in the developing limbs and in the axial domain of the developing body. In addition, we generated a targeted mutation in Hox A11 and characterized the resulting phenotype to begin to dissect developmental functions of the Abd-B subfamily of Hox genes. Hox A11 mutant mice exhibited double homeotic transformations, with the thirteenth thoracic segment posteriorized to form an additional first lumbar vertebra and with the sacral region anteriorized, generating yet another lumbar segment. Furthermore, skeletal malformations were observed in both forelimbs and hindlimbs. In mutant forelimbs, the ulna and radius were misshapen, the pisiform and triangular carpal bones were fused, and abnormal sesamoid bone development occurred. In mutant hindlimbs the tibia and fibula were joined incorrectly and malformed at their distal ends. Also, an enlarged sesamoid developed ventral to the tibiale bone. Both heterozygous and homozygous mice displayed mutant phenotypes adding an additional level of complexity to the Hox code hypothesis.

Animals↗

Pisiform and hamate coalition: case report and review of literature.

Pisiform and hamate coalition is a rare anomaly of the carpal bones; a symptomatic case is an especially rare condition. We report a case of symptomatic pisiform and hamate coalition in a 15-year-old Japanese male. The literature of pisiform and hamate coalition is reviewed.

Accidental Falls↗

Technical note: bone SPECT of the wrist.

A technique for single photon emission computed tomography (SPECT) during bone scintigraphy of the wrist is described. The technique has been developed as a means to improve localization of abnormalities observed on 99Tcm-MDP planar bone scintigraphy. A wrist phantom and 15 wrists in 13 symptomatic patients were examined. Good spatial detail was achieved, with the pisiform readily identifiable as a separate bone in six wrists. In seven cases the tomograms permitted better localization of planar image abnormalities and in four cases additional lesions were visible which were missed on planar scintigraphy. This technique can be applied to all patients with suspected carpal injury and allows better anatomical localization and greater sensitivity than planar scintigraphy alone.

Adolescent↗

The carpal bones in congenital hand anomalies: a radiographic study in patients older than ten years.

Abnormalities of the carpal bones in 192 anomalous hands of 154 patients older than 10 years were examined. Judging from the time of appearance of the pisiform, there was no delay of carpal bone maturation in these anomalies. There were differences between the carpal bones of three distinct groups: which included central polydactyly, syndactyly, and typical cleft hand; the group which included radial and ulnar deficiency, and the group which included symbrachydactyly and transverse defect. This suggests that there were differences between these groups in the timing and degree of injury to the limb bud or the hand plate in the course of development. It is thought that the first group originates from maldistribution of mesenchymal tissue of the limb bud (or of the apical ectodermal ridge), the second group from defects of that tissue, and the last group from defects of the mesenchymal tissue of the hand plate.

Adolescent↗

Vascularized os pisiform for reinforcement of the lunate in Kienböck's Disease: an average of 12 years of follow-up study.

PURPOSE: Little is known about the long-term results of vascularized bone transplantation for Kienböck's disease. This retrospective study investigated the long-term results of vascularized pisiform transfer. METHODS: We reviewed 23 patients to analyze results after vascularized pisiform transposition to a cored-out lunate for Lichtman stages II and III. Patients with ulnar-minus variance received additional radial shortening. RESULTS: Pain improved in 20 of 23 patients. Range of motion increased significantly relative to preoperative values but was only 80% that of opposite side. Grip power was 84% of the contralateral hand. At follow-up evaluation the mean Disabilities of the Arm, Shoulder, and Hand questionnaire score was 15.3 +/- 17.9 and the mean Cooney score was 82.4 +/- 10.0. Radiologically, out of 20 patients with preoperative x-rays Lichtman stage was unchanged in 11, improved in 3, and progressed in 6 patients. No patient showed radiologic signs of arthritis before surgery. At follow-up evaluation osteoarthritis was found in 7 of 22 patients. The majority of degenerative changes were of low grade and were seen at the radiocarpal joint. CONCLUSIONS: The results show high patient satisfaction and good function after vascularized bone transplantation for Kienböck's disease. In the long term vascularized pisiform transfer prevented lunate collapse in 16 of 22 patients.

Adolescent↗

The vascularity of the wrist. Identification of arterial patterns at risk.

The intraosseous and extraosseous vascularity of carpal bones was studied in 75 cadaver limbs. Vascular patterns were correlated with the clinical incidence of avascular necrosis, and at-risk patterns of vascularity were identified. The carpal bones were found to fall into three groups. Group 1, which consisted of the scaphoid, the capitate, and eight percent of the lunates, had either vessels entering only one surface or large areas of bone that were dependent on a single vessel. This group was the most vulnerable to posttraumatic avascular necrosis. The bones of Group 2, the hamate and the trapezoid, were characterized by the absence of internal anastomoses. Although these bones are theoretically at risk, they do not undergo avascular necrosis. Group 3 bones, which included the trapezium, the triquetrum, the pisiform, and 92% of the lunates, had rich internal anastomoses and were at least risk of undergoing avascular necrosis. Examination of the arterial anatomy of bones that undergo avascular necrosis in other regions of the body led to a classification based on the types of vascular interruptions that place particular bones at risk. In some, i.e., the scaphoid and the capitate, a pure intraosseous disruption resulted in avascular necrosis; in others, i.e., the femoral head and a small percentage of lunates, an extraosseous disruption was sufficient to produce avascular necrosis. A third class, which included the talus and the majority of lunates, had an adequate intraosseous blood supply and good extraosseous vascularity. This pattern required severe extraosseous or a combination of intraosseous and extraosseous injury to lead to avascular necrosis.

Arteries↗

High-resolution bone scintigraphy of the adult wrist.

Bony anatomic landmarks of the wrist (e.g., pisiform, hook of hamate, radioulnar joint, and styloid processes of the radius and ulna) were routinely identified in 28 adult patients examined for wrist pain. With the wrists prone and immobilized, bone scintigrams were obtained for 500,000 counts with an asymmetric (133 to 161 keV) Tc-99m energy window and either a converging (best choice) or straight-bore, high-resolution collimator. High-resolution scintigraphy precisely localized degenerative joint disease (nine patients), scaphoid fractures (five), pisiform fracture (one), lunate avascular necrosis (one), radioulnar arthritis (one), septic or inflammatory arthritis (six), ulnocarpal impingement (two), and reflex sympathetic dystrophy syndrome (two). Images obtained palm down with the wrist in ulnar deviation helped identify increased uptake within the scaphoid. Fracture and significant bone or joint disease were excluded in one patient.

Adult↗

The functional morphology of the cercopithecoid wrist and inferior radioulnar joints, and their bearing on some problems in the evolution of the Hominoidea.

The cercopithecoid wrist joint differs from the wrist joints of hominoids in several ways. The distal ulna, the distal radius, the pisiform, the triquetrum, the hamate, and the base of the fifth metacarpal are on the one hand remarkably alike among cercopithecoid genera, and on the other remarkably distinct from homologous bones in the Hominoidea. Functionally, the triquetrum and the pisiform, in conjuction with the ulnar styloid process, check the proximal carpal row during ulnar deviation, and are possibly important in stabilizing the wrist during dorsiflexion as well. The head of the ulna almost certainly betokens a range of radioulnar supination in cercopithecoids that is substantially less than is to be found in any of the hominoid genera. The articulation between the hamate bone and the base of the fifth metacarpal allows for considerable dorsiflexion in the Cercopithecoidea; this potential was not evidenct in any of the hominoids examined. Behaviorally, the cercopithecoid wrist can most profitably be viewed as an adaptation for a quadrupedal life style involving dorsiflexion of the wrist and palmigrade/digitigrade substrate contact. The hominoid wrist joint is not adapted for such a behavioral potential.

Animals↗

Recognition and treatment of uncommon carpal fractures.

Fractures of the trapezial ridge, hamate hook, and pisiform are often due to isolated, direct injury, but other carpal bone fractures are seldom isolated injuries. Midcarpal fractures should stimulate a search for associated perilunate injury; distal carpal row fractures suggest carpometacarpal fracture--dislocations or subluxations. Crush injury with fracture of the hamate, triquetrum, or trapezium may indicate an axial subluxation of the ulnar or radial carpus. Bone scans can be useful as a screening tool. Diagnosis will often require special radiographic techniques such as tomography. Carpal bone fractures are usually intra-articular, and treatment should be aimed at restoring joint congruity. Small extra-articular fractures and injuries to the pisiform can be successfully treated with excision.

Carpal Bones↗

Anatomic study of the pisotriquetral joint: ligament anatomy and cartilagenous change.

Eighty embalmed cadaver wrists (40 right and 40 left, 55 male and 25 female, aged 36 to 93 years [average age, 72.5 years]) were dissected to assess the anatomy of the pisotriquetral joint and the location of degenerative changes. The patterns of degenerative changes were classified into five types: type 1, central (8.8%); type 2, peripheral (38.8%); type 3, fan-shaped (13.8%); type 4, mixed (combination of > or =1 of types 1, 2, and/or 3; 10.0%); and type 5, total (12.5%). There was no cartilagenous change in 16.2% of the pisoform and 13.7% of the triquetrum. Degenerative changes (exposed subchondral bone and chondromalacia) on the articular surface of the pisiform were present in 83.3% of the wrists and on the triquetrum in 86.3% of the wrists. Degenerative changes were most commonly of the type 2 pattern (peripheral), with change located most commonly in the distal, distal-radial, and radial aspects of the pisiform and triquetrum. The ligamentous anatomy was categorized into 3 different types: type A, pisohamate and pisometacarpal ligaments inserted on the palmar distal aspect of the pisiform (52.5%); type B, pisohamate ligament inserted on the radial side of the pisiform and pisometacarpal ligament inserted on the palmar side of the pisiform (41.3%); and type C, type B anatomy with an additional ligamentous slip between the pisometacarpal ligament and the distal aspect of the hook of the hamate (6.2%).

Adult↗

Early abnormalities of pisiform and triquetrum in rheumatoid arthritis.

Erosions on the triquetrum and pisiform are frequent in early rheumatoid arthritis and occur characteristically at 3 sites. (a) A shallow erosion on the proximal medial triquetral "bare" area is related to synovial proliferation at the margin of the radiocarpal cavity, although compressive forces from an adjacent long ulnar styloid may be contributory; (b) an erosive abnormality on the distal medial triquetrum is related to synovial proliferation along the margin of the midcarpal joint; and (c) ring-like erosions on apposing surfaces of the triquetrum and pisiform are produced by pannus within the pisiform-triquetral compartment.

Arthritis, Rheumatoid↗