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At least 163 records · Page 9Linked to original sources
PubMed1995

Low spinal and pelvic bone mineral density among individuals with Down syndrome.

The bone mineral density of 15 adults with Down syndrome was compared to 25 control subjects without Down syndrome. Bone mineral density was measured by dual x-ray absorptiometry with a Lunar DPX scanner. Arm, leg, pelvic, and spine bone mineral density was tested. Analysis of covariance was conducted for each variable; Down syndrome was the independent variable, and the covariates were height, lean body mass, fat mass, age, and gender. No significant group differences were found for arm or leg bone mineral density. Individuals with Down syndrome had significantly lower pelvic and spinal bone mineral density. Before adjustment for covariates, percentage difference between group means for spine was 14.5% and for pelvis, 11.6%. Adjusted percentage was 11.1% and 13.9%, respectively. Suggestions for further research were made.

Adult↗
PubMed1998

[Radiation-induced osteonecrosis of the pelvic bones vs. bone metastases--a difficult differential diagnosis].

BACKGROUND: Since the introduction of megavoltage radiation therapy radiation osteitis has become a rare event and may be easily mistaken for bone metastases. A case of radiation osteitis is reported and diagnostic features are discussed. CASE REPORT: A 70 year-old female patient underwent rectum resection for rectum cancer and was given standard adjuvant therapy consisting of irradiation of the tumor site and lymph nodes in the pelvis with 18 MeV photons, boxfield technique up to 50.4 Gy and chemotherapy with 5-FU. Eight months later she complained of severe lower back pain. Plain radiographs and CT revealed osteolytic lesions in the ileosacral joints and os sacrum which appeared as circumscript areas of signal loss in MRI (T1-weighted sequence). A soft tissue mass was not detected. CT-guided biopsy excluded bone metastases. CONCLUSION: Characteristic features of radiation osteitis are spongiosa destructions initially in weight-bearing bones within the radiation field, namely the ileosacral joints, and the lack of pathologic soft tissue mass. False treatment, i.e. radiation for bone metastases, should be avoidable.

Aged↗