SEARCH · Search PubMed

Results for “MYOSITIS OSSIFICANS”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

SourceResearch connectionFrom yearThrough year

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 163 records · Page 9Linked to original sources

PubMed2001

Myositis ossificans traumatica of the temporal muscle: a case report.

Myositis ossificans traumatica (MOT) is a pathological condition characterized by extraskeletal formation of bony tissue, induced by violent or repeated trauma. Reports of this pathology occurring in the region of the head and neck are rare, and even more so in the muscles of mastication. We present the case of patient with MOT of the temporal muscle, the etiology of which seems to be related to traumatic manipulations during dental treatment. A review of the literature is presented and the surgical approach, which resolved this case is discussed.

Female↗

PubMed1982

Peripartum pseudomalignant myositis ossificans of the finger.

Two cases of pseudomalignant peripartum myositis ossificans of the finger are reported. The benign diagnosis is confirmed by the histologically characteristic zone phenomenon, consisting of a transition from an inner zone of proliferating spindle cells to a middle zone of well-oriented osteoid and finally to an outer zone of mature bone. In Case No. 1, because of the question of malignancy, a ray amputation was performed. In Case No. 2, the patient was observed during the peripartum period to show diminution in the size of the tumor. The lesion was eventually treated by local excision.

Adult↗

PubMed1996

[Dichloromethylenbiphosphonic acid in the therapy of myositis ossificans progressive (MOP)].

The authors report 3 cases of myositis ossificans progressiva (MOP) treated with i.v. dichloromethylenbiphosphonic acid. Two of these patients presented a severe development of the disease so that they could not walk anymore. After a few months of treatment with dichloromethylenbiphosphonic acid (300 mg/die for 10 continual days every month) sufficient recovery in motor capacity was achieved that walking was possible again. The favourable effect of therapy has been shown only by clinical features because there is no biological marker to monitor in the follow-up. During the treatment no side effect or modification of the markers of liver and kidney activity was observed.

Adolescent↗

PubMed1986

Myositis ossificans following porous-ingrowth TK replacement.

Clinically significant myositis ossificans of the distal thigh following virginal porous-ingrowth total knee arthroplasty has not been previously reported. Associated and potentially contributing factors in this particular case were (1) the patient's preoperative hypertrophic gonarthrosis, (2) our difficulty in regulating her postoperative sodium warfarin (Coumadin) dosages, (3) the postoperative knee manipulation, and (4) possibly, the additional surgical exposure of this patient's distal femur required to use the femur-based alignment instrumentation. Postoperative heterotopic ossification developing in the vicinity of a porous-ingrowth total knee prosthesis can have clinical significance. Treatment of this problem by a means that does not interfere with early bone ingrowth into the implant is a practical concern that warrants investigation.

Aged↗

PubMed2002

Traumatic myositis ossificans (ossifying pseudotumor) of temporal muscle.

The purpose of this paper is to present the clinical, radiographic, and histological aspects of a case of traumatic myositis ossificans of the temporal muscle. This is a rare, benign ossifying pseudotumor of skeletal muscles. It had developed 3 weeks after trauma to the left temple in a 33-year-old man. Differential diagnostic aspects of traumatic myositis ossificans confirming its benign character are discussed.

Adult↗

PubMed1980

Pseudomalignant myositis ossificans: heterotopic new-bone formation without a history of trauma.

Circumscribed heterotopic new-bone formation without a history of trauma is termed pseudomalignant myositis ossificans due to the diagnostic confusion of this benign lesion with malignant lesions. In 20 per cent of the published cases in which there were diagnostic problems, the patient underwent a radical procedure. Roentgenographically, pseudomalignant myositis ossificans is a circumscribed, radiopaque lesion with a central lucent zone that is separated from the underlying cortex by a radiolucent line. Histologically, a characteristic zoning pattern of peripheral maturation is present, the central proliferating zone usually causing the diagnostic problems. The ultrastructure of the lesion shows a regular mineralization front but an abnormal collagen periodicity of 300 angstroms. Excision is indicated for diagnosis and for relief of mechanical block or pain.

Adolescent↗

PubMed1977

[Difficulties in the differential diagnosis of a non-traumatic, active myositis ossificans during pregnancy (author's transl)].

A 28 year old patient complained of sensory disturbances and pain in the right upper arm during pregnancy. During the 32nd week of her pregnancy, a large painful mass developed in the flexor muscles which, radiographically, showed some calcification. A diagnosis of a parosseous sarcoma was made; biopsy, however, indicated a diagnosis of non-traumatic myositis ossificans. Since the histological appearances of active myositis may be vary difficult to distinguish from a juxtacortical sarcoma, a right brachial angiogram and scintiscan were obtained. The angiographic and scintigraphic findings were erroneously considered to suggest malignancy. Following delivery, the tumour was removed. Futher histology confirmed the diagnosis of localised, non-traumatic myositis ossificans. The value of radiology, biopsy, angiography and scintigraphy are discussed with reference to our experience.

Adult↗

PubMed2006

Pseudomalignant myositis ossificans mimicking osteosarcoma: a case report.

An ossifying soft-tissue lesion is potentially malignant. The possibility of malignancy increases in the absence of significant trauma. Pseudomalignant myositis ossificans can be easily confused with malignant lesions. A 22-year-old man presented with an ossifying mass in the adductor compartment of the thigh. The mass was excised and histopathologically reported as a soft-tissue osteosarcoma, but was later confirmed as pseudomalignant myositis ossificans by a pathologist specialising in oncology. Careful consideration and correlation of clinical, radiological, and histopathological findings is required to ensure the correct diagnosis is made and both initial and ongoing management is appropriate.

Adult↗

PubMedDate not supplied

[Myositis ossificans following extensive burns].

A report on a case of myositis ossificans following 50-60% burns (second to third-degree) on the trunk and extremities with periarticular localization of the ossification at the hip and knee joints. In terms of its extent and localization the ossification is primarily similar to post-paraplegic ossification of soft tissues.

Burns↗

PubMed1996

Fibrodysplasia (myositis) ossificans progressiva: clinicopathological features and natural history.

Patients with fibrodysplasia (myositis) ossificans progressiva (FOP) (n = 28) were studied for up to 24 years. All had characteristic short big toes potentially recognizable at birth; there were radiographic changes in the toes, thumbs, cervical spine and metaphyses of the long bones, including exostoses. Ossification in the large skeletal muscles began from birth to 16 years (mean age 4.6 years) initially in 25 patients in the neck and upper spinal muscles, and later around the hips, major joints and jaw. The rate and extent of disability was unrelated to the time of onset. There was no evidence that any form of treatment produced consistent benefit. Despite the unique combination of skeletal abnormalities and ectopic ossification, the first diagnosis in patients with FOP was often wrong and usually delayed after ectopic ossification began (mean 2.7 years, range 0-14). Except where presentation was unusual, such as progressive stiffness, this delay was mainly due to failure to recognize the significance of the abnormal toes. The most frequent erroneous histological diagnoses were soft tissue sarcoma or fibromatosis. This series emphasizes the usually incorrect initial diagnosis, the misinterpretation of the histology, the unpredictable prognosis and the failure of current treatment. Despite its extreme rarity, there is a need for wider knowledge of this condition both to avoid clinical errors and to stimulate research.

Abnormalities, Multiple↗

PubMed1998

Fibrodysplasia (myositis) ossificans progressiva. Clinical lessons from a rare disease.

Fibrodysplasia (myositis) ossificans progressiva is a rare dominantly inherited disorder, in which defects in skeletal patterning particularly affecting the big toes, are associated with progressive endochondral ossification of the large striated muscles in a specific order leading to prolonged disability. A recent series of 28 patients studied for as many as 24 years exemplifies the presentation and course of this disease. Painful swelling of muscles (myositis) leading to ossification began at a mean age of 4.6 years (range, 0-16 years) initially in the neck and upper spine (in 25 subjects) and later around the hips, other major joints, and jaw. The rate and extent of disability was unrelated to the time of onset. No form of treatment produced consistent benefit. Despite the unique clinical features, the initial diagnosis of fibrodysplasia ossificans progressiva was often wrong and usually considerably delayed. Mistaken histologic diagnoses such as soft tissue sarcoma or fibromatosis could lead to inappropriate treatment.

Adolescent↗

PubMed1954