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Patients with localized pancreatic adenocarcinoma in central Mississippi: a retrospective analysis of survival.

Factors influencing the survival of central Mississippi patients with adenocarcinoma of the pancreas were analyzed by a retrospective analysis of the two largest tumor registries in the state. The authors report that this Mississippi data agree with very recent reports describing significant benefit from chemoradiotherapy in localized disease, and suggests a less fatalistic attitude of the medical community towards localized pancreatic carcinoma is appropriate.

Adenocarcinoma↗

Infant hearing screening in Mississippi.

Four national professional associations through their representatives on the Joint Committee on Infant Hearing have endorsed the importance of early identification of hearing impaired children. In this article the author reports on the past seven years of the Infant Hearing Screening Program at the University of Mississippi Medical Center. He notes that efforts are currently underway to extend the IHS Program to other hospitals in Mississippi in cooperation with the Lions Club. At the present time 22 hospitals have been equipped to screen hearing in infants.

Female↗

Organochlorine pesticide residues in human milk samples from women living in Northwest and Northeast Mississippi, 1973-75.

Organochlorine pesticide analyses were performed on human milk samples obtained from 34 women living in the Mississippi Delta, a high pesticide usage area, and from six women living in Starkville, Mississippi, a low pesticide usage area. Nine women collected samples before and after their babies had nursed so that fat levels and sigma DDT levels could be compared on whole milk and milk fat bases. sigma DDT values were independent of collection time if calculated on a milk fat basis, but not if calculated on a whole milk basis. Thus, the most consistent indicator of DDT residues were values calculated on a milk fat basis. Residue levels for p,p'-DDE, p,p'-DDT, and sigma DDT were significantly different (P less than 0.01) in samples from the two areas. Residues of o,p'-DDT, beta-BHC, and oxychlordane in milk samples from women living in the high pesticide usage area also were significantly different (P less than 0.05). A mean value of 19.17 ppm sigma DDT, found in the milk fat of samples from the high pesticide usage area, is the highest ever reported. Samples from the low pesticide usage area contained a mean level of 2.36 ppm sigma DDT.

Adult↗

Self-treatment with herbal and other plant-derived remedies--rural Mississippi, 1993.

Herbal and other plant-derived remedies have been estimated by the World Health Organization (WHO) to be the most frequently used therapies worldwide. Therapeutic agents derived from plants include pure chemical entities available as prescription drugs (e.g., digitoxin, morphine, and taxol), standardized extracts, herbal teas, and food plants; plant-derived remedies can contain chemicals with potent pharmacologic and toxicologic properties. Although precise levels of use of these remedies in the United States are unknown, in 1991, herbal products accounted for sales of approximately $1 billion. Previous reports about herbal remedies in the rural South have described the use and biologic activities of locally gathered plant species and details of preparation and dosage, but have not determined the prevalence of use of plant-derived remedies in the study population and the prevalence of use of specific remedies. To assess the prevalence of use of plant-derived remedies (excluding prescription drugs) and the prevalence of use of specific remedies in rural central Mississippi, The University of Mississippi conducted a survey during March-June 1993. This report describes two case reports of use of these remedies and summarizes the findings of the survey.

Adult↗

Gallbladder surgery for Medicare patients in Mississippi.

Mississippi Foundation for Medical Care (MFMC) conducted a review of gallbladder surgery performed on Mississippi Medicare Patients using hospital claims files and limited record review for verification of claims file data. Significant error rates in the surgeon identification number were found in the claims files. It should also be noted that the current ICD-9-CM coding system does not allow for identification of laparoscopic cholecystectomies converted to open procedures. Past studies have attempted to use claims data alone for these types of analyses. These findings demonstrate the importance of using caution by those attempting to use claims data (without verification) to define patterns of hospital utilization, clinical outcomes and/or physician profiling. Claims data must be tested for validity for reliable pattern analysis. In addition, considerable variation was found among providers in elements such as conversion rates, complication and readmission rates. A few surgeons showed patterns for critical variables that were quite different from the universe. There was however, no statistically significant differences associated between volume of cases performed and outcomes. Time frame comparisons over several years show significant (> 80%) increase in gallbladder surgery since the introduction of the laparoscopic procedure.

Cholecystectomy↗

Mississippi: who's staffing our emergency departments?

Emergency services in Mississippi have come under scrutiny over the past few years. As part of a summer research project, we surveyed all 88 Mississippi emergency departments available to the public to determine physician staffing characteristics. At four times during one week (10 a.m. and 10 p.m. on a Tuesday and a Saturday), we determined whether a physician was present, their specialty, board certification/resident status, and whether they were from the community. Our paper presents and discusses the findings.

Emergency Service, Hospital↗

The University of Mississippi Medical Center's Antenatal Diagnostic Unit: on the cutting edge of tomorrow.

Prenatal diagnosis is a rapidly expanding field in the specialty of obstetrics. Modern providers of perinatal care must understand the fundamentals of inherited disease and keep abreast of advances in antenatal diagnosis. Pivotal in providing appropriate evaluation in this area is a referral center that is capable of affording the necessary evaluation, documentation and consultation. Although pregnancy termination is an option for some couples, many will use the information provided to prepare emotionally and financially for the birth of a child with special problems and needs. Some diagnoses will change obstetric management during the remainder of pregnancy or will lead to a recommendation for delivery at a tertiary medical facility. Other women with medical conditions warrant preconception counseling regarding pregnancy management and likelihood of a successful outcome. Patients with genetic disorders within their families may desire carrier detection through DNA analysis. Finally, women on medications at or near the time of conception frequently have concerns regarding potential teratogenesis. The ADU represents a commitment by both the Department of Obstetrics and Gynecology and the University of Mississippi Medical Center to furnish these services to providers and patients of the State of Mississippi.

Academic Medical Centers↗

Multistate outbreak of viral gastroenteritis related to consumption of oysters--Louisiana, Maryland, Mississippi and North Carolina, 1993.

On November 17, 1993, the state health departments of Louisiana, Maryland, and Mississippi notified CDC of several outbreaks of gastroenteritis occurring in their states since November 12. Preliminary epidemiologic investigations identified consumption of oysters as the primary risk factor for illness. On November 16, the Louisiana Department of Health and Hospitals (LDHH) had identified the Grand Pass and Cabbage Reef harvesting areas off the Louisiana coast as the source of oysters associated with outbreaks in Louisiana and Mississippi. Tagged oysters associated with outbreaks in Maryland were traced to the same oyster beds. The oysters harvested from these areas had been distributed throughout the United States. On November 18 and 19, the LDHH and CDC notified state epidemiologists of the potential for oyster-associated illness; outbreaks of oyster-associated gastroenteritis subsequently were identified in Florida and North Carolina. Collaborative investigations by state health officials, the Food and Drug Administration (FDA), and CDC were initiated to determine the magnitude and characteristics of the multistate outbreak, identify the etiologic agent, and trace the oysters. This report summarizes the preliminary findings of the ongoing investigation.

Acute Disease↗

The effects of malpractice on Mississippi physicians.

Medical malpractice and its effects on physicians in Mississippi is reviewed to assess its effects upon decisions in practice, patient care, and the physical and emotional toll on physicians. Through a random survey of 500 physicians in Mississippi across all areas of medicine it was determined that 47.3% of the respondents had been involved in malpractice litigation, a higher percentage than the United States average in 1989. The predominant emotional response to litigation was anger. Most physicians did not seek outside help as an aid in coping.

Adaptation, Psychological↗

Medical computing in Mississippi.

As our society enters the information age, physicians are finding an ever growing role for computers in the practice of medicine. Computers are used for education, research, medical record keeping, communications and as a powerful reference resource. They have even served as electronic consultants to assist in diagnosis and medical decision making. Mississippians have been pioneers in the use of computers in research and education and have taken a very progressive view of the future of medical computing in our state. Resources such as the Mississippi Health Sciences Information Network have served to connect rural health practitioners to academic centers and other informational resources and improve the quality of patient care throughout the state. Internet users will find that there are many Mississippi medical institutions that have home pages on the world wide web that also connects us to the global medical community. Computers are rapidly becoming one of the most important new tools in the black bag of the modern physician.

Computer Communication Networks↗

Infection control knowledge, practice, and attitudes of Mississippi dental hygienists.

PURPOSE: The purpose of this study was to assess Mississippi dental hygienists' knowledge and use of infection control techniques, attitudes pertaining to universal precautions and the risk of clinician/patient cross-infection, and attitudes toward treatment of patients with infectious diseases. METHODS: A 41-item questionnaire was mailed to all 508 licensed dental hygienists in Mississippi. Inactive, retired, and out-of-state hygienists (n = 59) were deleted from this study. The data were tested for significant associations using Chi-square. RESULTS: After adjusting for the 59 unusable returns, the response rate for analysis was 58% (n = 297). Dental hygienists reported using infection control techniques including sterilization or disposal of common items such as prophylaxis angles, suction tips, and air/water syringe tips. Although 98% of the respondents believed that barrier techniques were effective, some believed patients infected with HIV/AIDS (43%), hepatitis B (31%), or tuberculosis (40%) are best treated in public clinics rather than in private settings and that these clients pose a threat to dental hygiene practitioners. Further, a majority of the respondents believed that all oral healthcare workers and patients should be tested for HIV/AIDS. CONCLUSIONS: The incongruity between perceived knowledge, reported practice, and attitudes suggests the need for continuing education courses designed to allow dental hygienists to explore the affective domain regarding the care of patients with infectious diseases. In addition, courses on working with patients with HIV/AIDS should be offered in smaller cities for greater accessibility.

Adult↗

Endemic blastomycosis in Mississippi: epidemiological and clinical studies.

In order to clarify the epidemiology and clinical spectrum of endemic blastomycosis, we reviewed the charts of 326 culture and/or histologically proven cases of blastomycosis in Mississippi from 1979 to 1988. Cases were dispersed throughout the state, but counties in central and south-central Mississippi reported 63% of all blastomycosis cases. The average annual incidence rate was 1.3 cases per 100,000 population. The majority of cases were in men (male to female ratio 1.7:1), and most patients were aged in their third through seventh decades (82%). Outdoor occupations were noted for only 28.9% of cases. Cases occurred throughout the year with no significant seasonal peak. Although 55% saw a physician within 7 days of onset of illness, 29% presented after 1 month. Despite early presentation, diagnosis was often delayed for more than 1 month (43.3%). Single organs were involved in 82.8% of cases. For all cases, organ systems involved included lungs (91.4%), skin (18.1%), bone (4.3%), genitourinary system (1.8%), and central nervous system (1.2%). The presence of skin or bone disease was associated with multiorgan involvement. Thirty-three patients died (11.5%), 6 of whom received no therapy. Patients who died were significantly older than those who survived. A successful outcome without relapse was noted in 86.5% of amphotericin B-treated patients and in 81.7% of ketoconazole-treated patients. The relapse rate for ketoconazole-treated patients was higher than for amphotericin B-treated patients (14% and 3.9% respectively).

Adolescent↗

Outpatient diabetes management of Medicare beneficiaries in four Mississippi fee-for-service primary care clinics.

BACKGROUND: As part of a quality improvement initiative aimed at increasing physician compliance with standards of care for diabetes patients, diabetes practice patterns among Medicare beneficiaries in four primary care clinics were examined in Mississippi. METHODS: Retrospective chart reviews of Medicare beneficiaries with a diagnosis of diabetes were conducted to examine physician compliance with recommended diabetes monitoring services. RESULTS: Fifty-three percent of all beneficiaries did not have a recorded A1c test while 54 percent did not have a recorded foot exam. The percentage without foot exams decreased with quarterly visits. Seventy-two percent and 68 percent of patients had testing for lipids and proteinuria, respectively, although variability in types of testing performed was seen. Seventy-six percent of beneficiaries did not have a referral for a dilated eye exam. CONCLUSIONS: The study has uncovered, within several primary care sites in Mississippi, variable documentation of compliance with many clinically relevant recommendations relating to the care of elderly patients with diabetes. These items can be targeted for improvement as part of a statewide quality improvement initiative for Medicare beneficiaries.

Aged↗

A longitudinal evaluation of the Mississippi Scale for Combat-Related PTSD in detecting war-related stress symptomatology.

The long-term psychological effects of war-related stress were assessed 3 years after the Persian Gulf War with the Mississippi Scale for Desert Storm War Zone Personnel (M-PTSD-DS), developed from the Mississippi Scale for Combat-Related PTSD (M-PTSD: Keane, Caddell, Taylor, 1988). The M-PTSD-DS scores of 30 Marine reservists were compared with the number of DSM-III-R PTSD criteria each met at two points in time, initially at 3 months after the Gulf War and again 3 years later. Findings support the construct validity (sensitivity) of this scale in the immediate and longitudinal measurement of relatively nonpathological degrees of war-related stress in reservists not involved in direct fighting. Initial level of PTSD symptomatology upon returning from a war zone was predictive of M-PTSD-DS scores 3 years later. This scale was effective in detecting varying degrees of war-related stress in this self-selected group of reservists and warrants further study.

Adult↗

Use of the Mississippi scale for combat-related PTSD in detecting war-related, non-combat stress symptomatology.

This study investigated the effectiveness of the Mississippi Scale for Desert Storm War Zone Personnel (M-PTSD-DS), developed from the Mississippi Scale for Combat Related PTSD (M-PTSD; Keane, Caddell, & Taylor, 1988), in the measurement of varying degrees of war-related post-traumatic stress (PTS) symptomatology of non-combat Persian Gulf War veterans. Thirty Marines were administered the M-PTSD-DS after 3 months of active duty in Operation Desert Storm. The M-PTSD-DS scores of the Marines were related significantly to the number of PTS symptoms reported by the Marines. This scale appears to be quite effective in detecting varying degrees of war-related stress in non-combatants.

Adult↗

Natural and anthropogenic processes that concentrate Mn in rural and urban environments of the lower Mississippi River delta.

This study evaluated natural processes and projected methylcyclopentadienyl manganese tricarbonyl fuel additives as sources of Mn accumulation in the environment. Data sets include fresh alluvium and sediments from the lower Mississippi River Delta and a soil metal survey of metropolitan New Orleans. The (1) railroad Mn, (2) industrial Mn, and (3) dynamic aquifer-stream transfer of Mn hypotheses were tested with the Mississippi River Delta data. Friction between Mn-rich steel wheels and rails contributes Mn (P = 0.017) to the environment, supporting (1). Sediment loads of Mn were similar (P = 0.77) upstream and downstream from the Louisiana industrial corridor, not supporting (2). The median Mn on the alluvium surface (59 mg/kg), in the aquifer (159 mg/kg), and in the riverbank aquifer discharge zone (513 mg/kg) support (3) as a mechanism for Mn enrichment of clay. The New Orleans soil metal survey data set shows a rural to urban increase of fourfold for Mn and three orders of magnitude for Pb. At 1999 U.S. highway fuel use, 8.3 mg of Mn per L would yield 5000 metric tons of Mn annually. If 13% of Mn were emitted, 650 tons of Mn would become aerosols annually, while 87% or 4350 tons would remain in engines. The 1999 toxic release inventory for Mn shows 370 tons as total emissions compared to the potential of 390 and 260 tons from vehicles, respectively, in urban and rural areas. A precautionary lesson from the use of Pb as a fuel additive is that the use of Mn as a fuel additive would be associated with an increased risk for neonates exceeding the estimated total tolerable daily intake of 2.1-16.5 micrograms Mn (especially in urban inner city environments) because neonates lack fully functional hepatic clearance for Mn.

Fresh Water↗

A short form of the Mississippi Scale for measuring change in combat-related PTSD.

In large-scale surveys or program evaluations, investigators most often wish to assess multiple domains of functioning, while at the same time minimizing the overall length of the data collection protocols. In addition, studies of treatment interventions require instruments which offer the greatest opportunity of detecting change in the variables of interest. Toward these ends, we present an 11-item version of the Mississippi Scale for Combat-Related PTSD. The sample was composed of 436 war zone veterans who received specialized outpatient treatment for PTSD, and who were followed up in 4-month intervals for 1 year. Items were identified for inclusion in a short scale on half of the sample. The scale was then cross-validated on the other half. This short form of the Mississippi Scale has good internal consistency, good correspondence with the full scale, significant sensitivity to change in symptom severity, and significant relationships between change and clinicians' ratings of improvement after 1 year, number of treatment sessions received and number of months in treatment.

Adult↗

The potential for faking on the Mississippi Scale for Combat-Related PTSD.

The Mississippi Scale for Combat-Related PTSD is widely used in the assessment of post-traumatic stress disorder (PTSD). The high face-validity of the scale may make it vulnerable to faking, however. The present study found that the scores of individuals instructed to respond "as if" they had PTSD did not differ from the scores of veterans with PTSD. Furthermore, although veterans who were diagnosed as having PTSD were found to have significantly higher Mississippi Scale scores than those who did not meet diagnostic criteria for PTSD, the mean score for all groups (veteran and non-veteran) exceeded the originally recommended diagnostic cut-off score of 107. A cutoff score of 121 was found to best differentiate veterans with PTSD from veterans who did not meet diagnostic criteria for the diagnosis, with high sensitivity but relatively low specificity.

Combat Disorders↗