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At least 163 records · Page 9Linked to original sources
PubMed1990

[Improvement of the transthoracic method of puncture sanitation in complex treatment of lung abscess].

A method of transthoracic puncture sanitation treatment of the cavity of a lung abscess with the use of a needle of an original design and the proteolytic enzyme karipazyme (0.5% solution) is suggested. Fifty-two patients with abscess of the lung (main group) were treated by this method, 46 (88.4 +/- 4.4%) were cured, in 5 (9.6 +/- 4.1%) transformation to a chronic abscess occurred, one patient (1.9 +/- 1.7%) died. Transthoracic puncture with a commonly used needle and administration of antibiotics into the cavity of the abscess were performed in 57 patients (control group). Thirty-eight patients (66.7 +/- 9%; p less than 0.05) recovered, chronic abscess formed in 14 patients (27.6 +/- 5.9; p less than 0.05), 5 patients (8.7 +/- 3.7%) died. The duration of treatment of patients in the main group was reduced by 16.1 days. The method of skin coloured liquid-crystal thermography was employed in 28 patients to determine the optimal point for puncturing the abscess, as the result of which complications were avoided and the number of failures in puncture of the lung destruction cavity reduced by half.

Anti-Bacterial Agents↗
PubMed1975

Treatment of aspiration pneumonia and primary lung abscess. Penicillin G vs clindamycin.

Aspiration pneumonitis and lung abscess generally involve anaerobic bacteria, which normally colonize the upper respiratory passages. The therapeutic response of these infections to parenteral penicillin G (49 patients) and parenteral clindamycin (35 patients) was compared to determine relative efficacy. No difference was discerned between these two agents in terms of time required for defervescence, roentgenographic clearing, and ultimate outcome. Seven patients with infections including Bacteroides fragilis were treated with penicillin G, and all responded well. These data indicate that penicillin G is the preferred agent for pulmonary infections involving anaerobic bacteria. Clindamycin is a suitable alternative for patients in whom penicillin G is contraindicated.

Anaerobiosis↗
PubMed1996

Lung abscess in patients with AIDS.

We identified 31 patients with human immunodeficiency virus (HIV) infection and lung abscess. All patients had advanced HIV disease, and the mean CD4 cell count was 17/mm3 (range, 2-50/mm3). Twenty-two patients (71%) had previous opportunistic infections, and 24 (77%) had previous pulmonary infections. Symptoms at the time of presentation included fever (90% of patients), cough (87%), dyspnea (35%), pleuritic chest pain (26%), and hemoptysis (10%). The microbiological etiology was established for 28 patients, and the pathogens recovered were bacteria (65%), Pneumocystis carinii (6%), fungi (3%), and mixed microorganisms (16%). The pathogens included Pseudomonas aeruginosa (11), Streptococcus pneumoniae (6), P. carinii (5), Klebsiella pneumoniae (5), Staphylococcus aureus (4), Aspergillus species (3), viridans streptococcus (2), Haemophilus influenzae (1), Streptococcus milleri (1), Proteus mirabilis (1), and Cryptococcus neoformans (1). Mycobacterium tuberculosis was not isolated; two patients for whom a microbiological etiology was not established responded to antituberculous therapy. Patients were treated for 2-12 weeks; 25% of the patients received > 4 weeks of therapy. The outcome was poor: 36% of the patients had recurrences, and 19% died. In patients with AIDS, lung abscess is associated with advanced HIV infection, is due to a broad spectrum of pathogens, responds poorly to antibiotics, and has a poor prognosis.

AIDS-Related Opportunistic Infections↗
PubMed1980

Corticosteroids and malnutrition. Aspergillus lung abscess in an asthmatic child.

An adolescent developed invasive pulmonary aspergillosis in the limited form of a lung abscess. She had a weak immunologic response to the infection. Her depressed immunity was the result of prolonged corticosteroid therapy, compounded by malnutrition. In spite of this and other complications of corticosteroids, she made a full recovery from the fungal infection following treatment with amphotericin B and surgical excision of the lung abscess.

Adolescent↗
PubMed2001

[Local use of recombinant interleukin-1 beta in the complex treatment of patients with acute lung abscess].

An analysis of results of examination and treatment of 59 patients with a prolonged duration of acute abscesses of the lungs has shown the influence of immune disorders on the dynamics of the development and outcome of pyo-destructive disease in the lung. The indications to local immunosubstituting therapy were determined. A new original method of administration and a scheme of prescription of the medicine Betaleukin are proposed. Clinical efficiency of the method proposed is shown. The local immunocorrection used in the complex treatment of patients with acute abscesses of the lungs allows to get recovery of 89% of the patients.

Acute Disease↗
PubMed1998

[Lung abscess resulting from esophageal carcinoma successfully treated with intraesophageal covered self-expandable metallic stent].

An 82-year-old man was admitted to our hospital with high fever and back pain. He already suffered from esophageal carcinoma and expandable metallic stent had been inserted because of esophageal stenosis. A chest x-ray film obtained on admission showed infiltrative shadows in the right lower lung filled. The diagnosis of lung abscess was made on the basis of aspirate findings. Despite closed drainage, antibiotic treatment, and fasting therapy, progressive pulmonary infiltrates developed. Esophagography and esophagoscopy revealed that an esophageal fistula due to an advanced esophageal carcinoma had caused the lung abscess. An additional covered self-expandable metallic stent (EMS) was placed on the surface of the esophageal carcinoma, close to the esophageal fistula. This promptly resolved the lung abscess. Our conclusion was that the covered-EMS can be effective for the palliation of esophagorespiratory fistulas.

Aged↗
PubMed1979

Staphylococcal lung abscess and acute glomerulonephritis.

A patient with a staphylococcal lung abscess developed acute glomerulonephritis with clinical and pathological features typical of postinfectious glomerulonephritis. There was no evidence of streptococcal infection and the nephritis resolved following treatment of the abscess.

Acute Disease↗
PubMed1989

[The successful surgery of lung abscess formed from pulmonary aspergilloma in a patient with recurrence of acute promyelocytic leukemia during remission induction therapy].

This is a case report of a successful case of surgical treatment of a lung abscess formed from pulmonary aspergilloma in a patient with a recurrence of acute promyelocytic leukemia during remission induction therapy. A 39 year-old woman was admitted to our hospital for remission induction therapy of a recurrence of acute promyelocytic leukemia. We were successful in bringing her to a state of complete remission by a therapy of a intermediate-dose of Ara-C. Pulmonary aspergilloma was formed in the right lung during therapy. We performed transbronchial infusions to Amphotericin B which dissipated the fungus ball. However, a lung abscess was formed. We needed radical therapy, and there were no complications in the following surgical treatment. Recently, along with the tendency for the use of stronger chemotherapy treatment regimes for acute leukemia, there has been an increase of the number of mycosis cases such as the pulmonary aspergilloma case reported here. Accordingly, surgical treatment is becoming more and more a matter of necessity in the clinical course of leukemia patients.

Adult↗
PubMed1991

[Comparative analysis of functional activity of bronchoalveolar lavage fluid and peripheral blood cells in patients with acute lung abscesses].

Upon comparative evaluation of functional activity of bronchoalveolar lavage (BAL) cells and those of peripheral blood in patients with acute lung abscesses it was found that BAL cells reflect more pronounced changes in functional activity of immunocompetent cells. Investigation of immune status in acute lung abscesses demonstrated the significance of a clinical pattern of the disease and severity of purulent destruction. The relationship may be also inverse, i.e. the specific response of the immune system to antigenic loading ++pre-determines relevant form of the disease. The addition of pleural ++pyo-inflammatory side effects is probably due to phagocytic insufficiency. Functional derangements of phagocytic system are similar to those in gangrene though less distinct.

Acute Disease↗
PubMed1991

Presentation of echinococcus infection as lung abscess.

A 35-year-old man presented with clinical and radiological features of lung abscess. Despite broad spectrum antibiotics for 5 weeks he remained systemically unwell. Underlying Echinococcus infection was suspected when repeat radiology of his chest showed a water lily sign, and this diagnosis was confirmed at thoracotomy. Hydatid disease may present as lung abscess and cause delay in diagnosis and appropriate therapy.

Adult↗
PubMed1976

Anaerobic (putrid) lung abscess in adolescence.

Two adolescents with acute anaerobic (putrid) lung abscess were seen during an influenza epidemic. One patient, who had a history of seizures and a dental infection, had a classic predisposition to this disease. In the second patient, the abscess was apparently acquired as a complication of influenza. In both cases, the preliminary diagnosis was staphylococcal pneumonia with pneumatocele. It is suggested that failure to consider an anaerobic cause in pulmonary infections, inappropriate specimens, transport and culture of anaerobic material, and the sensitivity of oral cavity-derived anaerobes to penicillin, serve to mask the true frequency of anaerobic lung infections in childhood and adolescence.

Adolescent↗
PubMed1983

Lung abscess revisited. A survey of 184 cases.

One hundred eighty-four patients with lung abscess, admitted to the Hospital of the University of Mississippi between 1960 and 1982, were studied with respect to sex (149 men and 35 women), age (mainly fourth to sixth decades), location of abscess(es) (RLL, RUL, and LLL mainly), predisposing factors (aspiration in sensorium disorders, obstruction, gingivo-dental suppuration, immunoincompetence) and nonoperative (89%) and operative (11%) therapy, usually lobectomy. Data from the different decades were compared, but there were few major differences. Mortality rate was 22% in the 1960s, 25% in the 1970s, and 28% in 1980-1982. Major management problems involved massive pulmonary hemorrhage, impaired immune defenses, old-age debility, bronchopleural fistula with empyema, or very large cavity. Anaerobic bacteria predominate and penicillin is the treatment of choice. Incidence of operation is declining, but cases are more often complicated. Prognosis is good in the uncomplicated case.

Adult↗
PubMed1981

Lung abscess complicating transbronchial biopsy of a mass lesion.

We report a rare complication of transbronchial lung biopsy. A lung abscess developed after transbronchial biopsy of a peripheral mass lesion. Persistent fever, leukocytosis, and roentgenographic evidence of increase in size of the biopsied mass are useful clues for the diagnosis of pneumonia surrounding a tumor.

Adult↗