[A new insect repellent--hexamethylenebutansulfamide].
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Animals↗
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Synthesis of insect-repellent amino analogs of 2-ethyl-1,3-hexanediol (Rutgers 612).
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Alcohols↗
Laboratory evaluation of diethyl phenyl acetamide & other insect repellents against rat flea, Xenopsylla cheopis (Rothschild).
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Acetamides↗
[Study of remote results of the use of insect repellents. IV. Study of the embryotoxic properties of N-benzoylpiperidine and carboxide].
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Animals↗
Allergic contact dermatitis due to an insect repellent: double sensitization to picaridin and methyl glucose dioleate.
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Adult↗
Reye-like syndrome associated with use of insect repellent in a presumed heterozygote for ornithine carbamoyl transferase deficiency.
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Autopsy↗
Gas chromatographic identification of urinary metabolites of insect repellent N,N-diethylphenylacetamide on inhalation exposure in rats.
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Acetamides↗
A study of insect repellents. 1. Effect on the flight and approach by Aedes aegypti.
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Aedes↗
Distribution and excretion of a new insect repellent, 14C-DEM, in the mouse after intravenous, cutaneous, and oral administration.
The distribution of 14C after administration of 14C-DEM was qualitatively similar irrespective of the administration route (intravenous, cutaneous or oral). The major accumulation sites were lacrimal and nasal glands, parotis, liver, and kidney. The main excretion was through the urine and only minor quantities through the faeces and the expired gases. It could be confirmed that the new repellent had a low skin uptake.
Acetamides↗
Structures of three oxygenated 24-methyl-steroids (nic-3, -7, and -11) from the insect repellant plant Nicandra physaloides (Solanaceae): x-ray analysis of Nic-3 acetate and nic-11 ethyl ether.
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Epoxy Compounds↗
Topical use of DEET insect repellent as a cause of severe encephalopathy in a healthy adult male.
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Administration, Topical↗
Distribution and fate of the insect repellent 14-C-N, N-diethyly-m-toluamide in the animal body. I. Distribution and excretion after injection into mice.
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Amides↗
Blood biochemical changes induced by insect repellent N,N-diethylphenylacetamide in rats.
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Acetamides↗
[Resistance of insect repellents to washing off with water after their application to cloth and skin (laboratory tests)].
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Aedes↗
Laboratory testing of the insect repellents IR3535 and DEET against Phlebotomus mascittii and P. duboscqi (Diptera: Psychodidae).
The efficacy of the repellent IR3535 was tested and compared with DEET using two laboratory colonies of phlebotomine sand flies, Phlebotomus mascittii and Phlebotomus duboscqi. P. duboscqi, originating from Senegal, is a proven vector of Leishmania major. P. mascittii (Corsican origin) has never been demonstrated to be a vector of leishmaniasis, but it was reported in 2004 as an anthropophilic species in Germany associated with autochthonous visceral leishmaniasis in people and animals. IR3535 and DEET were tested at an effective concentration of 10% in ethanol on two (one male, one female) human volunteers. The mean protection time against P. duboscqi was 5.9h for both repellents, against P. mascittii 10.4 and 8.8 h for IR3535 and DEET, respectively.
Animals↗
Insect repellency of N,N-diethyl-m-toluamidine--a nitrogen isostere of Deet.
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Aedes↗
Toxicologic studies of an insect repellent N, N-diethylphenylacetamide.
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Acetamides↗
Stereochemical effects in an insect repellent.
Racemic 1-[3-cyclohexen-1-ylcarbonyl]-2-methylpiperidine repels blood-feeding arthropods such as mosquitoes, chiggers, and ticks. The compound contains two asymmetric carbon atoms and the racemate consists of four stereoisomers. Quantitative mosquito bioassays using Aedes aegypti (L.) showed that (1S,2'S) and (1R,2'S) configurations were 2.8-3.1 and 1.6-1.8 times more effective, respectively, than the other two stereoisomers in reducing mosquito bites. (1S,2'S) was 2.5 more repellent than the racemate. Biological data show that an interaction of the (2'S)-2-methylpiperidine configuration with a repellent receptor system in A. aegypti is apparently important to repellent activity. Nuclear magnetic resonance spectra and molecular mechanics calculations for the stereoisomers provided insight into the conformation of the (2'S)-group. Results indicate that enhanced repellent effects can be realized through formulation of the most active stereoisomers of the compound.
Aedes↗