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Study of HLA antigens of the Martinican population.

This is the first time a study has been undertaken on the HLA profile of the Martinican population, a population which is essentially the product of intermixture between African-Negroes and French Caucasians. Two hundred and thirty-eight nonrelated subjects were typed for the A and B loci, 158 subjects for C locus and 128 for DR locus. After analysis of our parameters (antigen and gene frequencies, linkage disequilibria, etc.) and their comparison to those found in the Black and Caucasian control populations, we came to the conclusion that our racially-mixed population is closer to the African-Negro population than to the French Caucasian. A study of the average gene flow enabled us to evaluate the Caucasian contribution as being about 30%. This figure is subject to change inasmuch as racial intermixture continues. Socio-cultural variables are assumed to play a minimal role, given the high rate of illegitimacy.

Africa↗

Non-accidental injury: a two-year study in central Liverpool.

In the two years following the implementation in Liverpool of a case conference system for dealing with non-accidental injury to children, 76 children were discussed at 73 such conferences. Factors in both the children and their families were identified as predisposing to non-accidental injury, notably male sex, illegitimacy, low birthweight, previous injuries in the children, the mothers having become pregnant at an early age, and the families having environmental stress factors. The evolving rôle of the case conference system in providing support for affected families is discussed.

Age Factors↗

Factors associated with spontaneous pre-term birth.

Factors associated with spontaneous pre-term birth in 283 singleton pregnancies were compared with those present in a total population of 16 994 women at risk studied in the First British Perinatal Mortality Survey. It was shown that the risk of spontaneous pre-term birth was related to low maternal age, low maternal weight, maternal smoking, low social class, illegitimacy, threatened abortion, and a previous history of antepartum haemorrhage, perinatal loss, or low birth weight livebirths.

Birth Weight↗

Factors associated with low birth weight of infants delivered at term.

The singleton births in the 1958 British Perinatal Mortality Survey (Butler and Bonhan, 1963; Butler and Alberman, 1969) were used to study the aetiology of low birth weight of infants delivered at term. After exclusion of macerated stillbirths and infants with lethal congenital defects, 468 infants of 259 days or more gestation and a birth weight which was less than 2500 g were identified. The mothers and their pregnancies were compared with those of the population of 16 994 singleton births. Delivery at term of a low birth weight infant was significantly associated with maternal prepregnant weight, maternal height, maternal smoking, primiparity, maternal employment, low social class, a previous infant of low birth weight, threatened abortion and severe toxaemia. No significant associations were found with illegitimacy, area of residence, previous spontaneous abortion, essential hypertension, mild toxaemia, chronic or acute infections or other conditions. There were significant negative associations with a history of previous large infants and with maternal blood group AB.

Adult↗

National differences in extraversion and neuroticism.

A method is proposed for measuring national differences in extraversion and neuroticism from demographic and epidemiological data. The method is to use national prevalence rates of a number of variables and treat them as indices of the levels of extraversion and neuroticism in national populations. The variables taken are the national rates of divorce, illegitimacy, accidents, crime, murder, suicide, alcoholism, chronic psychosis and coronary heart disease; and the per capita consumption of calories, cigarettes and caffeine. Data for these indices are presented for the advanced western nations. The relationship of these variables to extraversion and neuroticism among individuals is used to set up a model for their relationship among nations. The variables were factored by principal components analysis and this yielded two major factors identified as extraversion and neuroticism. The factor scores of each nation on the two factors were then computed. These indicate that the most extraverted nation is the United States and the most introverted is Japan. The most neurotic nation is Austria and the least neurotic is Ireland.

Austria↗

Asian mothers' risk factors for perinatal death--the same or different? A 10 year review of Leicestershire perinatal deaths.

A case-control study of all perinatal deaths in Leicestershire was established in 1976. By 1985 some 1342 singleton perinatal deaths had occurred. Perinatal mortality among patients of Asian origin was consistently higher than that among European women. Many of the sociomedical risk factors for perinatal death known at booking were common to both population groups. In this population of Asian women, however, low social class was not associated with perinatal risk and illegitimacy hardly ever occurred. In contrast, previous infertility among the Asian women was associated with risk of perinatal death, while no such association was found with European women. In 19% of perinatal deaths care was either inadequately provided or taken up. The case-control design in these circumstances provides a practicable way to evaluate causal factors and at the same time to provide information of value to educators and health service planners.

Adolescent↗

Predicting psychiatric admission rates.

OBJECTIVE: To determine the numbers of actual and expected psychiatric admissions for the residents of the district health authorities of England and to develop a model to indicate which social, health status, and service provision factors best explain the variation of the actual from the expected psychiatric admissions; to use this model to predict psychiatric admission for district health authorities as an aid to resource allocation. DESIGN: The actual psychiatric admission for district health authority residents were extracted from data of the 1986 Mental Health Enquiry. Expected admissions were calculated using the age, sex, and marital status structure of each district health authority and the national psychiatric admission rates related to age, sex, and marital status. Standardised psychiatric admission ratios were calculated as the ratios of the numbers of actual to expected psychiatric admissions. A wide range of social, health status, and service provision data were used as the explanatory variables in regression analyses to determine which combination of factors best explained the variation between districts of standardised psychiatric admission ratios. SETTING: The 168,652 psychiatric admissions recorded for the 1986 Mental Health Enquiry, after exclusion of mental handicap and psychogeriatric admissions. RESULTS: The actual number of psychiatric admissions varied from 79% above to 54% below the expected number of admissions from age, sex, and marital status for the districts of England. The most powerful variables to explain this variation were the rate of notification of drug misusers, standardised mortality ratios, and levels of illegitimacy in each district. A complex model was developed which could be used to predict district psychiatric admissions as an aid to resource allocation. A simpler model was also developed (which was less powerful than the more complex model) based on the underprivileged area score. One advantage of this model was that it could be used at the level of electoral wards as well as district health authorities.

Adolescent↗

A comparative review of Asian and British-born maternity patients in Bradford, 1974-8.

The perinatal mortality rate for Asian babies born in Bradford during the five years 1974-8 was persistently higher than for babies born to United Kingdom mothers. A comparative review of 18 924 British indigenous and 6443 Asian immigrant maternity patients delivered in Bradford from 1974-8 demonstrated several differences between the two ethnic groups. Factors operating in favour of Asian women were fewer teenage mothers, lower rates of illegitimacy, and fewer smokers. On the other hand, a greater number of factors presented increased risks to Asian patients-more women aged over 35, lower social class, higher parity, shorter pregnancy intervals, previous perinatal deaths, shorter duration of antenatal care, anaemia, shorter gestations, more babies born without professional help, and more low-birthweight babies. Local health education programmes are now concentrating on encouraging expectant mothers to attend early and regularly for antenatal care, to breast-feed their babies, and to increase the interval between pregnancies to at least one year.

Adolescent↗

Medical authority and nursing integrity.

This paper explores the respective legitimacy or illegitimacy of medical authority over nursing work. The analysis makes use of Joseph Raz's ideas concerning the nature of authority. Various scenarios are considered which lend themselves to differing interpretations, and the conclusion reached is that acting in accordance with legitimate medical authority enhances rather than compromises the nurse's professional integrity. Difficulties, however, may lie in disentangling legitimate from illegitimate attempts to control nursing work.

Attitude of Health Personnel↗

Correlation between molecular and conventional genealogies in Aicuña: a rural population from Northwestern Argentina.

Aicuña is a village in the northwest of Argentina, located about 300 km south of La Rioja city, in the province of La Rioja. The population of Aicuña derives from a founder couple established in the uninhabited Aicuña valley in the early years of the 17th century. Due to land ownership litigation, the descendants maintained a well-documented genealogy that extends for 12 generations, comprising more than 8,000 individuals. From the historical pedigree of Aicuña, we selected 14 males with direct patrilineal descent from the 2 most ancient male founders, and 23 donors (9 females and 14 males) with direct matrilineal descent from the most ancient female founder. All 3 founders lived in the 17th century. We collected DNA from buccal swabs and characterized the mitochondrial DNA (mtDNA) and Y haplotypes using 14 Y-specific markers, 11 mtDNA polymorphic markers and sequencing of the mt hypervariable regions 1 and 2. We found four different Y haplotypes: Y1 and Y2 haplotypes of European origin corresponding to the founder ancestors Francisco Páez de Espinoza and Apolinario Ormeño, which were shared by 6 and 3 donors, respectively. Three males selected as Ormeño patrilineal descendants showed a different Y haplotype (Y3), probably originated by erroneous paternity registration due to illegitimacy. The remaining case (haplotype Y4), also assumed to belong to the Ormeño lineage, was probably also due to an erroneously registered paternity. Twenty-two donors showed an association of mtDNA markers corresponding to the Amerindian haplotype A2. The founder of this matrilineage could be traced back for more than 14 generations. The haplotype B of one remaining female did not correspond with the historical pedigree and could be due to an error in the genealogy registration. Our results showed an 85% agreement between conventional and molecular genealogies, with mtDNA markers being Amerindian, and Y markers being European. The methodology used in this report is a tool which could potentially be employed as a precedent for land ownership by Aicuña villagers and Amerindian populations.

Argentina↗

A boy with 46, X, del, Y, due to a de nove mutation.

A newborn male referred for genetic investigation because of a large sized head and dysplastic ears, but with apparently normal male genitalia was found to have a deletion of all of the brightly fluorescent part of the long are of chromosome Y and absence of the Y fluorescent body on buccal smear. His father and his two brothers had normal Y chromosomes. Social and family history as well as marker investigation make illegitimacy most unlikely and leaves an occurrence of a new chromosomal mutation in the father the most probably interpretation. Follow-up of the infant to the age of 9 months revealed a large baby with normal development.

Body Height↗

Fatherless children and Accouchement sous X, from marriage to demarriage: a paradigmatic approach.

The author proposes a paradigmatic approach to the construction of fatherless, abandoned, and/or motherless children as social issues needing some policy responses: within the different historical Western configurations of the repertoire of potential responses, major organizing paradigms draw the line between those responses that are rejected as belonging to the supreme evil sphere and others that can be considered as lesser evils. Within the framework of a paradigm, dilemmas exist and debates go on as to which lesser evils should be preferred and how the policies should be implemented. Policies deriving from different paradigms give rise to intractable controversies since the disagreements concern not only the means but also the ends. Four paradigms can be extracted from the historical data with regard to illegitimacy and single motherhood: Christian angelism, Malthusian angelism, healthy citizenship, and proper citizenship.

Child↗

Disappointment and desolation: women, doctors and interpretations of puerperal insanity in the nineteenth century.

Taking case notes as the key source, this paper focuses on the variety of interpretations put forward by doctors to explain the incidence of puerperal insanity in the nineteenth century. It is argued that these went far beyond biological explanations linking female vulnerability to the particular crisis of reproduction. Rather, nineteenth-century physicians were looking at other factors to explain the onset of insanity related to childbirth; stress and environmental factors linked to poverty, family circumstances, poor nutrition, illegitimacy, fear and anxiety, and the strains of becoming a mother. The main focus is on female asylum patients, but all mothers were seen as being susceptible to puerperal insanity.

Birth Certificates↗

Suicide in Cork and Ireland.

The official suicide rate in Ireland increased markedly between 1970 and 1985. This is genuine increase in suicide and not an apparent one due to previous deficiencies in recording practices. Possible reasons for this change include an increase in 'anomie' shown by a rise in the rates of crime, illegitimacy and admissions to hospital for alcoholism, a decline in social cohesion revealed by a fall in the marriage rate and a rise in the number of separated couples, and an increase in unemployment.

Adolescent↗

The effects of reasons given for ineligibility on perceived gender discrimination and feelings of injustice.

We examine whether the reason given for a negative outcome influences the likelihood of making gender discrimination attributions. Men and women were given one of four reasons for their ineligibility to attend an event: an explicit gender reason, a reason based on an attribute correlated with gender, that same gender-related reason with explanatory information attached, or they were given no reason. Providing participants with a reason based on a gender-related attribute deflected them from making attributions to gender discrimination, indicating that discrimination attributions can easily be averted. Adding explanatory information to the gender-related reason decreased feelings of injustice, illegitimacy and anger while increasing acceptance of the outcome.

Adult↗

Putting into words, putting to rest and putting aside the ancestors. How an analysand who was heir to the Armenian genocide of 1915 worked through mourning.

The author discusses the intergenerational psychic transmission of collective trauma on the basis of her personal experience as a descendant of victims of the Armenian genocide of 1915. She shows how the processes of transmission are encumbered within a diaspora community such as hers by the incorporation of objects in the throes of mourning, the invalidation of prohibitions by murder-become-law, and lack of differentiation between the sexes. A parallel is drawn between the characteristic secrecy of the genocidal project on the part of the perpetrators and the sense of illegitimacy of the victims' descendants, exacerbated in the case of the Armenian catastrophe by the refusal of the state that inherited the genocide to confess to it and consequently its erasure from Western consciousness. The author describes how she was enabled to emerge from confinement in the trauma by her French schooling and her analysis, and subsequently became able to work through mourning and writing, by divulging the secret and in particular the publication of her father's deportation diary. The written text is seen as a shroud in which the dead can finally be interred. Presenting an episode from her schooldays, she demonstrates the importance of her immersion in French culture in allowing her to achieve the necessary linguistic and psychic distance from her heritage.

Armenia↗

Catholicism and indices of social pathology in the states.

In 50 states, percentages of Catholic residents correlated negatively with suicide and divorce rates and positively with abortion rates. The percentages of Catholic residents did not correlate with homicide and illegitimacy rates.

Abortion, Induced↗

The relation between states' adoption of English as their official language to demographic and social pathology variables.

Comparisons indicated that the 20 states which adopted English as their official language since 1984 had lower percentages of high school graduates and higher rates of motor vehicle fatalities among their residents than did those states that did not enact such laws. The two types of states did not differ in homicide, suicide, divorce, illegitimacy, or rape rates based on 1990 census data. Also, they did not differ in terms of percentages of residents who were foreign-born, college graduates, imprisoned, unemployed, or who spoke a language other than English in the home.

Cross-Sectional Studies↗