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At least 163 records · Page 9Linked to original sources
PubMed1983

Growth hormone responses to apomorphine HCl in schizophrenic patients on drug holidays and at relapse.

In nine schizophrenic patients on drug holiday, growth hormone (GH) response to apomorphine HCl 0.75 mg (APO) was compared with normal control data. Patients were tested at two month intervals for up to 14 months. Seven patients relapsed, and of these, five had exaggerated GH responses to APO at that time. Of these five, three had exaggerated GH responses to APO prior to clinical deterioration. Further work is required to determine whether this test can be a useful predictor of relapse.

Adult↗
PubMed1998

[Effect of walking during all weekdays, holidays, and at work on mental and physical health in workers].

In order to clarify the effects of walking under various psychosocial and occupational conditions on psychophysiological health, we examined the relationship between the number of steps walked in several situations, such as on all weekdays, at work, and over the weekend, and the results of medical checkups, psychological tests, Breslow's 7 health practices, and other attitudes toward walking as well as health by using a pedometer in a certain manufacturing company. Most of the workers estimated their usual number of steps walked as being less than actual levels on both weekdays and holidays. Generally, the increased number of steps walked was significantly correlated with increased HDL-cholesterol levels, and decreased Triglyceride levels. Contrary to such physical effects, there were more variations with respect to the relationship between walking and psychological health. Moreover, the development of a walking habit at work resulted in some factors becoming worse, such as relaxation, trait anxiety, and serum AST levels when compared to those on all weekdays and over the weekend. In conclusion, it is necessary to consider several situations in which workers usually walk and we must also practice counseling and education for health promotion, to promote walking for health care in the workplace.

Adult↗
PubMed2004

Waterborne outbreak among Spanish tourists in a holiday resort in the Dominican Republic, August 2002.

On 3 September 2002, the Spanish national centre of epidemiology (Centro Nacional de Epidemiologia--CNE) was alerted to a high number of gastroenteritis cases in Spanish tourists who had travelled to a hotel in Punta Cana on different days during august 2002. Entamoeba hystolitica cysts have been visualised by microscopy in the stools of several patients that sought medical attention in the Dominican Republic. The CNE informed the health authorities in the Dominican Republic and conducted in conjunction an epidemiological investigation. A descriptive study of the 76 initial cases estimated a mean illness duration of 5.1+2.9 days and a exposure period of 3.6+2.2 days. Following a retrospective cohort study, the attack rate was found to be 32.4%. Consequently, 216 (95% CI=114.75-317.25) spanish tourists had probably developed the illness. Stool samples were collected in Spain from untreated patients who still felt unwell. None of the samples were positive for E.hystolitica. On 10 September, a hygiene inspection was undertaken at the hotel. Samples of the ice and meals served at the buffet that day, yielded coliform bacteria. Consumption of water from the resort water system was the only risk factor associated with the symptoms (RR= 3.55; 95% CI =1.13-10.99). To avoid similar outbreaks occurring again at the hotel, it is essential to regularly monitor the water quality and to improve food handling hygiene standards. Basic food hygiene training for food handlers should be mandatory. An international guideline for the management foodborne and waterborne outbreaks among tourists in holiday resorts should be drawn up, involving all competent authorities of both destination and tourist origin countries.

Adult↗
PubMed2005

Paroxysmal atrial fibrillation after recreational marijuana smoking: another "holiday heart"?

Paroxysmal atrial fibrillation (AF) is a common arrhythmia that may occur after various triggers. With the exception of the well recognized "holiday heart" associated with acute alcohol consumption, the cause of AF is rarely identified in young adults. We report a case of paroxysmal AF after marijuana smoking in a 22 year old female with no other identifiable triggers and normal echocardiography. Marijuana smoking should be included in the list of possible triggers in young adults presenting with paroxysmal AF, once cardiac disease and other common causes of AF have been excluded.

Adult↗
PubMed2006

Acute renal failure after a holiday in the tropics.

A 20-year-old, previously healthy woman, presented with high fever, headache and myalgia 3 days after her return from a holiday in Southeast Asia. Laboratory data on admission demonstrated a pronounced increase in plasma creatinine, marked thrombocytopenia and moderately elevated liver aminotransferases. After having ruled out malaria, dengue fever was primarily suspected and supportive intravenous fluid therapy was initiated. Still, 1 day after admission, platelet counts dropped even further and she became anuric although she did not appear hypovolemic. On day 2 after admission, urine production commenced spontaneously and the patient slowly recovered. All laboratory test results had returned to normal approximately 2 months later. Serological analysis for dengue fever was negative. It turned out that the patient had been trekking in the jungle while in Thailand and we, therefore, analyzed serology for Leptospira spirochetes which was clearly positive. The patient was diagnosed with leptospirosis which is a serious condition associated with a high mortality when complicated by acute renal failure. Differential diagnoses in patients with acute renal failure and tropical infections are reviewed. The importance of early recognition of leptospirosis, and prompt treatment with antibiotics in suspected cases, is emphasized.

Acute Kidney Injury↗
PubMed1989

Japanese encephalitis after a two-week holiday in Bali.

Japanese encephalitis is described in a 10-year-old girl after a short holiday in Bali. Four days after returning to Australia the patient presented with a high fever, stupor and rapidly-developing focal neurological signs. Recovery occurred gradually over a period of three months and she has returned to school. Japanese encephalitis viral infection was confirmed by a marked rise in specific haemagglutination-inhibition antibodies and the presence of immunoglobulin M antibodies to the flavivirus group. It is important to be aware of the possibility of arboviral infection in patients with encephalitis. In view of the recent outbreaks of Japanese encephalitis in Asia, travellers to the region should be warned to protect themselves from mosquito-bites.

Acute Disease↗
PubMed1983

The "holiday heart": electrophysiologic studies of alcohol effects in alcoholics.

Although the "holiday heart syndrome," highlighted by rhythm disturbances after acute alcohol ingestion, is well known, the potential arrhythmogenic effects of alcohol have not been studied. Fourteen patients (two with congestive cardiomyopathy) with a history of rhythm disturbances and alcohol consumption were studied electrophysiologically. One patient had nonsustained ventricular tachycardia, one had nonsustained atrial fibrillation, one had paired ventricular responses, and the remainder had no response to the extrastimulus technique. After 90 mL of 80-proof whiskey, 10 of the 14 patients developed sustained or nonsustained atrial or ventricular tachyarrhythmias. Significant prolongation of His-ventricular conduction was seen after alcohol intake; this was noteworthy as one of the patients had previously shown Mobitz II atrioventricular block after acute alcohol consumption. Alcohol in modest doses has the potential to produce rhythm disturbances in patients with a history of chronic alcohol consumption and heart disease.

Adult↗
PubMed1984

Considerations in the implementation of drug holiday programs in long-term care facilities.

Drug holiday programs have been implemented in many long-term care facilities in North America to reduce drug use, decrease nursing time in drug administration, and assess the need for drugs in elderly patients. Before the program begins, adequate preparation of staff and discussions among patients and families are encouraged. The pharmacist's role is to coordinate inservice programs for nursing and medical staff, develop policies and procedures, dispense drugs as prescribed and assist in program evaluation.

Aged↗
PubMed2004

[Before going on a diving holiday--consider this].

A prerequisite for all those who go in for the sport of scuba diving is mental and physical fitness. This must be checked within the framework of an examination for diving fitness before first taking up the sport, and should be rechecked every one to three years. For fitness for diving, not only lung function, ECG and tubal function need to be normal--the psychological profile of the holiday maker also plays an important role under water. For he or she must be able rapidly and reliably to recognize a dangerous situation and to react to it appropriately. Thorough training and the compliance with the rules of diving offer protection from many of the risks of this underwater sport--for example, problems with the ears or sinuses can be avoided. The most common cause of fatal diving accidents is a barotrauma of the lung with rupture of the alveoli on ascending.

Aerospace Medicine↗
PubMed1989

[Changes in arterial pressure and adrenergic activity during a holiday at a mountain at low altitude].

To answer the question often asked by hypertensive patients whether it is advisable for them to spend a holiday in the mountains for fear of a rise in blood pressure, 12 untreated mild hypertensive and 12 normotensive subjects underwent 24-hour non-invasive blood pressure monitoring, plasma catecholamines assay (HPLC) and plasma renin activity determination at home (sea level) and in a mountain resort (1210 m). The 2 evaluations (at home and in the mountains) were performed in a cross-over fashion. The ICR Spacelabs Pressuromaster and the Del Mar Avionics Pressurometer IV were used: blood pressure was measured every 8 minutes during daytime and every 15 minutes during sleep. Blood pressure was also recorded during a 1.5 to 3 hour excursion by cable-car to a height of 3006 m. Average 24-hour blood pressure at sea level was 134/86.7 mmHg in the hypertensive subjects and 115.8/73.6 mmHg in the normotensive ones. At 1210 m, it rose to 140.6/90.2 mmHg (n.s.) and to 120.8/74.9 mmHg (n.s.) respectively. Twenty-four-hour profiles showed that the blood pressure difference was present only during waking hours, while during sleep blood pressure levels were similar at sea level and in the mountains.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1981

[Dracunculus medinensis infestation following holidays in West Africa. Epidemiological implications (author's transl)].

All 50 patients with dracunculiasis admitted to a Paris hospital during a 3-year period were West African immigrant workers, 70% of whom came from a very limited geographical area. Only 6 of the workers were "first arrival"; the others had contracted filariasis during holidays in their home country. The mean duration of stay in hospital was 40 days. In 40 of the patients who had spent 6 months or less in their home country, the exact dates of first arrival in France, departure to, and return from, Africa and emergence of adult worms were available, so that the duration of the Dracunculus medinensis cycle (mean: 12 +/- 1,7 months) and the period of local transmission could be determined. These epidemiological data account for the seasonal character of infestation and for the occurrence of dracunculiasis in France. They also exclude a diagnosis of filariasis based on more or less suggestive symptoms when the delays after possible infestation are either too long or too short.

Adult↗
PubMed1984

The "holiday heart" syndrome.

The potential arrhythmogenic effects of alcohol have recently been studied electrophysiologically. These experiments have confirmed clinical observations that alcohol in modest doses has the potential of producing atrial or ventricular arrhythmias. Although many of the patients have underlying heart disease, there are reports of patients with no evident heart disease where acute alcohol injestion has caused arrhythmias. This sequence of events, i.e., cause and effect, has been referred to as the "holiday heart" syndrome.

Alcohol Drinking↗
PubMed1983

Changes in cardiovascular risk factors in diabetic children during a camping holiday.

Diabetic children in a holiday camp were divided into two groups according to physical activity. In the active group a significant elevation of HDL-cholesterol and a highly significant decrease in total/HDL-cholesterol ratio were observed. In the inactive group similar but non-significant changes occurred. No appreciable changes were observed in the serum albumin level but the fasting FFA level decreased in both groups, more markedly in the active group. Therefore, the FFA/albumin quotient and also body fat percent decreased considerably in the active group while in the inactive group there were no significant changes.

Adolescent↗
PubMed1994

Advising your clients on a healthy holiday.

Immunisations often need to be started two or three months before departure, so advise clients to consult the practice in good time. A pre-travel health interview can be an excellent focus for health education. Parents of young children going abroad may benefit from advice on infant feeding avoiding sunburn and being up to date with immunisations. Advice on prevention and treatment of gastrointestinal infections is useful, especially for parents of young children. Giving the correct advice for malaria is particularly important. For example, many patients who formerly lived in malarious areas wrongly believe they are immune. These days more holiday makers are asking about HIV and sexual health, giving the nurse a good opportunity for health education about condoms, safer sexual practices and avoiding infection through contaminated needles and blood products.

Adolescent↗
PubMed1995

Apomorphine SC treatment in parkinsonian patients with long-term L-dopa syndrome during L-dopa drug holiday.

The Long-Term Dopa Syndrome (LTDS) is one of the main problems in the management of advanced parkinsonian patients. A transient L-Dopa withdrawal (Drug Holiday, DH) can be useful to improve the drug response after DH, even if this approach presents risks due to patient akinesia. We tried to verify if Apomorphine sc administration during DH (DH with Apomorphine, DHA) can: a) reduce the risks connected with DH: b) maintain the benefits of DH: c) standardize the duration of DH. Twenty-five parkinsonian patients with LTDS were treated with Apomorphine sc during DH (14 days). No patient had any severe side effects. The follow-up at 180 days, conducted using the Unified Parkinson's Disease Rating Scale, demonstrated a significant improvement in the clinical conditions of about 70% of the patients, allowing a 27.1% reduction in daily L-dopa dosage. DHA can represent a valid therapeutical approach for parkinsonian patients with LTDS.

Adult↗