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At least 163 records · Page 9Linked to original sources
PubMed2006

[Epidemiology of childhood tuberculosis in Libreville, Gabon from 1997 to 2001].

The purpose of this retrospective study was to determine the epidemiological features of tuberculosis patients under the age of 15 years treated at the Tuberculosis Control Center in Libreville, Gabon from 1997 to 2001 as a basis for improving management. Study criteria included age, sex, BCG vaccination status, social level, type of tuberculosis, HIV status and outcome of treatment. Statistical analysis was performed using EPI INFO software. The childhood tuberculosis rate was 9% with a sex ratio of 1.02 and the most common age group was 0 to 4 years. Three fourths of children were from poor zones and 90% had received BCG vaccination. The incidence of tuberculosis did not increase from year to year. The location of tuberculosis was pulmonary in 77% of cases (n=433) and extrapulmonary in 23% (n=129). No case involving meningitis or miliary disease was observed. Sputum bacilloscopy was positive in 21% of cases involving pulmonary tuberculosis and HIV serology was positive in 4.4% of children tested. The success rate was 54%. Tuberculosis-related mortality was 0.7% but 37% of children were lost from follow-up. Efforts to control tuberculoses by screening children exposed to bacilliferous conditions and vaccinating newborns must be continued. Treatment for tuberculosis must be given free of charge and under medical supervision as recommended by the World Health Organization.

Adolescent↗
PubMed1991

Prevalence and type of infertility in Gabon.

The prevalence and type of infertility based on the WHO criteria were determined in a rural and semi-rural population in south-eastern Gabon. The prevalence rate of infertility in the rural population was 5.7% for primary infertility and 20.0% for secondary infertility. In the semi-rural area, 3.0% suffered from primary infertility and 22.4% from secondary infertility. Pregnancy wastage and home delivery were risk factors for secondary infertility. An evaluation of the WHO criteria for fertility surveys was made.

Abortion, Spontaneous↗
PubMedDate not supplied

[Diagnostic problems with cerebral vascular accidents in Gabon].

This retrospective study covers a period of eleven years (1977-1988). It concerns 365 patients who developed a cerebrovascular accident or stroke and originated from different provinces of Gabon. The authors report their experiences in order to emphasize the diagnostic problems and the need of computerized tomography.

Adolescent↗
PubMed1991

[Role of cryptosporidiosis in infants in Gabon. Results of two prospective studies].

Two epidemiological surveys of cryptosporidiosis in urban and suburban areas of Libreville, Gabon, Equatorial Africa, were conducted in children. On 450 fecal samples on the first study, Cryptosporidium sp. has been seen about 3.11%. For the second survey, on 296 children, aged between 0 and 2 years, with acute diarrhoea, the rate of infestation was 24%. The maxima was observed for infants aged between 6-18 months, in case of malnutrition and during wet seasons.

Acute Disease↗
PubMed1991

[Spinal and spinal cord injuries. Therapeutic approach in Gabon].

The authors present their experience with 81 cases (66.4%) of acute cervical spine injuries (C.S.I.) and 41 cases (33.6%) of acute thoracolumbar spine injuries (T.L.S.I.) treated by a multidisciplinary approach, at Jeanne Ebori Hospital (Libreville, Gabon) between the years 1981 and 1987. Traffic accidents were the leading cause of injury. The largest group consisted of patients in their third decade. The anatomic localizations were: upper cervical spine: 22 cases (27%); lower cervical spine: 56 (69%); upper thoracic spine: 11 (26.8%); lower thoracic spine or thoracolumbar area: 19 (46.3%); lumbar spine: 7 (17%). There were osteoligamental lesions in 3 cases (3.7%) of C.S.I. and 4 (9.7%) of T.L.S.I. Clinically, 44 patients (54.3%) with C.S.I. and 37 (90.2%) with T.L.S.I. had neurological deficits. Surgical indications depended upon the osseous as well as neurologic lesions. There were five important steps in the treatment of spinal injuries associated with neurological deficit: (1) immobilization, (2) medical stabilization, (3) spinal alignment (skeletal traction), (4) operative decompression if there was proven cord compression, and (5) spinal stabilization. Twenty patients (24.6%) with cervical injuries were treated conservatively (traction, collar, kinesitherapy); 53 (65.4%) underwent a surgical intervention (anterior approach - 21, posterior fusion - 30, combined approach - 2); and in 8 patients (9.8%) refraining from surgery seemed the best alternative. After lengthy multidisciplinary discussion, the authors elected not to operate on tetraplegic patients with respiratory problems that necessitated assisted ventilation, because of its fatal outcome. Of injuries to the thoracolumbar spine, 13 (31.7%) were treated conservatively (bedrest, orthopedic treatment). Twenty-eight patients (68.2%) with unstable thoracic and lumbar fractures associated with neurologic deficit required acute surgical intervention (stabilization with or without decompression of the neural elements). Laminectomy alone was performed in 5 cases, laminectomy with graft in 2, stabilization by Roy-Camille plates in 16 and by Harrington rods in 5. Most upper thoracic spine fractures were treated conservatively. Surgical intervention was increasingly possible with the availability of more material and qualified staff. There were 17 patients (21%) who died from C.S.I. (15 were tetraplegic), and 6 (14.6%) from T.L.S.I. In general, osteoligamental consolidation was satisfactory. Neurological recovery was observed only in patients with partial deficits. Most cases posed socioeconomic problems.

Adult↗
PubMed1991

[Chemoprophylaxis of Plasmodium falciparum malaria by a combination of 100 mg of chloroquine and 200 mg of proguanil per day in a zone III of chloroquine resistance (Gabon). Study of 431 French soldiers].

Incidence of P. falciparum malaria in french non-immune soldiers serving in Gabon for four months has increased from 21% in 1987 to 37% in 1988. Since 1989, in a first step, the personal protection measures were reinforced. Thereafter, the usual chemoprophylaxis (chloroquine 100 mg daily) was replaced by a daily association of chloroquine 100 mg and proguanil 200 mg. A 85% decrease of malaria incidence was observed in 431 soldiers. The effects of the personal protection strengthening and of the new chemoprophylaxis can be evaluated to be respectively responsible for 50% and 71% decrease. Among the secondary effects, gastric pain was the most frequent, but it was never a cause of chemoprophylaxis stopping. The mouth ulcer frequency was far lower than that elsewhere reported. No significant biological abnormalities could be related to the chloroquine-proguanil association.

Animals↗
PubMedDate not supplied

[Epidemiologic aspects of malaria in Gabon].

The authors report the results of 3 sample surveys carried out in Libreville, Ngounié and Haut-Ogooué Provinces to evaluate the main malarial indexes among 0 to 15 years old children in Gabon. These investigations would suggest that malaria is mesoendemic in the three areas. The systematic presumptive antimarial treatment of fever attacks is widely used in Libreville but not so frequent in rural areas.

Adolescent↗
PubMed1989

[Malaria in Gabon. Bioclinical survey of non immune Europeans during short stay and prophylactic attitude].

A group of 300 young European adults visiting Gabon for relatively short periods was surveyed monthly for malaria from a parasitological, clinical, immunological, hematological point of view. The regular increase of fevers due to malaria from 1984 to 1988 and the multiplication of cases of amino-4-quinoline resistance in the plasmodial parasites call for new prophylactic considerations for this group residing in this heavily malaria infested area.

Adult↗
PubMed1989

[Development of chloroquine resistance in Plasmodium falciparum in Gabon between 1984 and 1987-88 (in vivo evaluation in a school environment)].

Unknown in 1980, suspected in 1983 and scarcely present in 1984-85, Plasmodium falciparum resistance to chloroquine as studied in vivo in schoolchildren in Gabon, has strongly developed in 4 years time. In 1987-88, administration of 25 mg/kg of chloroquine leaves one strain out of four with a parasitic load greater than 10/1.000 red blood cells examined by thick drop technique. The present, unfortunately provisional attitude tends to maintain chloroquine at efficient doses for as long as the resistant strains are ethically and practically controllable. The dispersion without strict control of new and for the time being very efficient drugs might rapidly give rise to a polychemoresistance which would leave us without defence.

Animals↗
PubMed1989

[Uterine rupture. Apropos of 31 cases seen at the Hospital Center of Libreville (Gabon)].

The authors report 31 cases of rupture of the uterus at the Hospital of Libreville-Gabon. The frequency is 1.4/1,000 deliveries. The usual etiological factors are found: malformations of the uterus, obstetrical maneuvers, mechanical dystocias, use of oxytocics, scars of caesarean section. The clinical characteristics are those previously described. There were two maternal deaths and 17 fetal deaths. These figures emphasize the progress accomplished and to come.

Adult↗
PubMed1989

Hepatitis B and delta infection in Gabon: a seriological survey in a representative sample of the province of Haut-Ogooue.

Hepatitis B virus markers and antibodies to delta agent were studied in adult people (15-54 years) in the province of Haut-Ogooue (Gabon), randomly selected by cluster sampling technique. Of the 384 people, 37 (9.6%) were positive for HBsAg, of which 23 (62.2%) were positive for HBeAg; 246 (65.3%) had anti-HBs and 53 (13.8%) had anti-HBc as the only marker. Chronic carriage of HBV defined as presence of HBsAg or exclusive anti-HBc was observed in 90 people (32%). At least one of the HBV markers was found in 89% of the people. Women were more frequently positive than men. No difference in relation to age was observed. Anti-delta was found in 12 (3.5%) of the 341 people with HBV markers and 7/12 of these could be considered as chronic HBV carriers.

Adolescent↗
PubMed1989

Seroprevalence of treponemal infection in rural and semi-rural communities in south-eastern Gabon.

A sero-epidemiological study on the prevalence of treponemal infection was performed in a representative sample of adult women in rural and semi-rural communities in south-eastern Gabon. The overall prevalence of treponemal infection was 10.1% and 9.2% in the group of pregnant women. Age-adjusted prevalence rates were significantly lower in the rural than in semi-rural area, 7.7% and 12.2% respectively (p less than 0.05). This was due to the significantly lower syphilis prevalence in the age group 15-29 years in the rural area. There was no statistically difference in age-adjusted prevalence rates in women with different fertility status or pregnancy outcome.

Adolescent↗
PubMed1988

[Seroprevalence of syphilis in urban and semi-rural populations of Gabon].

The seroprevalence of syphilis was studied in an urban and a semi-rural community in Gabon by a cluster sampling technique. The crude prevalence rate of treponemal infection in the semi-rural population was estimated to be 13.3 +/- 5.0% and in the urban population 19.4 +/- 4.6%. The age-adjusted prevalence rate was significantly higher in the urban than in the semi-rural population. In both areas, it was significantly higher in men than in women. No significant difference was observed according to age. These high rates indicate the need for a control program for sexually transmitted diseases.

Adolescent↗
PubMed1988

[Malaria in Gabon. Transplacental passage and dynamics of development of fluorescent antimalarial antibodies with age].

In permanent malaria transmission area (Gabon), fluorescent malarial antibodies have been studied among a population of mothers new borns and children from 1 to 15 years old. A lack of transplacental transfer of antibodies among african pairs "cord-mother" is noticed and in negative correlation with total mother IgG level. The antibodies rapidly increase from 1-2 years old still 9. Chimioprophylaxis does'nt modified for a long time the development of the FAT malarial antibodies.

Adolescent↗
PubMed1987

[Drug resistance of Plasmodium falciparum malaria in Equatorial Africa. Apropos of cases observed at a military unit stationed in Gabon].

The existence of Plasmodium falciparum chloroquine-resisting clones in equatorial Africa is quite a recent event. Among a French military unit of 138 people who had lived in Gabon from April to August 1986, 24 of them have caught malaria due to Plasmodium falciparum. This allows us to perceive the impact of this event because of the perfect control of chloroquine prophylaxis and the good knowledge of all the attacks of fever which occurred in the field. Admitting 10 of those people into the department of internal medicine of the Military Hospital Desgenettes located in Lyons, we could have seen that trophozoites of Plasmodium falciparum were still persisting 2 months after their return for 8 of them in spite of carrying on chemoprophylaxis. Observing that in the field, sets the problem of the chemoprophylaxis of malaria for the troops maneuvering in chloroquine-resisting areas and warrants, if justified, a work protocol aimed at solving it.

Adult↗