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PubMed1975

[Contribution of gastroscopy with aimed biopsy to the diagnosis of early gastric cancer].

Gastroscopy was carried out in 320 patients with gastric cancer. In 35 instances, the tumour was located in the mucosa or barely extended into the submucosa. Diagnostic corroboration was obtained by means of biopsies conducted during the examination. Gastric fibroscopy can now offer early diagnosis of carcinoma of the stomach. A barium meal often fails to reveal these lesions, especially in the initial stages, nor can it indicate whether an ulcer is benign or a tumour. The fact that biopsy can be performed at the same time is of fundamental importance in determing whether medical or surgical management should be chosen.

Adult↗

PubMed2001

[Holter ECG monitoring during gastroscopy in patients with chronic atrial fibrillation].

The authors present their results obtained with Holter ECG monitoring during gastroscopy in a group of patients with chronic atrial fibrillation. In one third of the group, endoscopic procedure induced complex cardiac arrhythmias and also significant myocardial ischaemia. These findings can have serious hemodynamic consequences. Therefore previous evaluation of cardiac findings and extemporaneous for urgent therapeutical intervention are necessary. To these patients, especially to those with cardiac arrhythmias--including atrial fibrillation--it is necessary to devote intensified attention and precaution with interdisciplinary co-operation.

Aged↗

PubMed2002

[Virtual gastroscopy. Preliminary experience].

OBJECTIVE: To define the role of virtual gastroscopy (VG) in the detection of elevated lesions comparing its results with conventional endoscopy (CE) as the gold standard method. MATERIALS AND METHODS: Between December 2000 and July 2001, 19 patients were evaluated. The age ranged between 41 and 72 (mean 58.8 years old). VG and CE were performed in all the patients during the same week. VG were carried out with a multislice CT scanner (Mx 8000, Marconi Medical Systems). The technical parameters used were 3 mm with slices and 1.5 mm reconstruction intervals. The acquisition time was 22 seconds. Images were sent to a workstation (MxView, Marconi Medical Systems) where they were reprocessed in three different ways: 1) Bidimensionally 2) Tridimensionally 3) Virtual Endoscopy Findings of VG were compared with CE. RESULTS: VG detected 39 lesions, whereas CE detected 40 lesions. There were 39 true-positive findings, 2 true-negative findings, 0 false-positive findings and 1 false-negative findings. The Sensitivity (Se) was 97.5%; Specificity (Sp) was 100%, positive predictive value 100% and Negative predictive value 66%. CONCLUSIONS: VG is a new non-invasive method with high Se and Sp in the detection of elevated lesions. The actual role of VG consist in identification of gastric lesions and possibility to diagnose gastric disease.

Adult↗

PubMed1992

[Spontaneous perforation of ulcers after gastroscopy].

Six cases of spontaneous perforation of penetrating gastric and duodenal ulcers following insufflation of air during gastroscopy are reported. Despite the favorable situation (empty stomach, rapid diagnosis), the prognosis of this complication is relatively poor, since the patients involved are often elderly, have multimorbidity and represent a high surgical risk.

Abdomen, Acute↗

PubMed1991

[Value of gastroscopy in postoperative patients with gastric cancer].

From September 1980 to May 1987, fiberoptic gastroscopy was performed in 3538 patients. Of them, 356 (10%) had received operation for gastric cancer. A second primary cancer was found in 31 cases, recurrent gastric cancer in 18 and adenoma in 87. Among the 138 asymptomatic operated patients, a second primary cancer developed in 8, and 6 of them were in the early stage. In the 218 symptomatic operated patients, a second primary cancer developed in 23, and 10 of them were in the early stage. The results suggest that gastroscopic examinations at regular intervals are mandatory for asymptomatic postoperative patients.

Adenoma↗

PubMed1990

[Detection of Campylobacter pylori in gastric mucosa--relation to gastroscopy findings and degree of gastritis].

In 862 unselected gastroscopies we could confirm the high percentage of campylobacter pylori infection in the antral gastric mucosa strongly associated with chronic superficial gastritis and active inflammatory signs. Significant correlation with age concerned the normal findings only. In patients with duodenal ulcers we found in 91% gastritis and in 88% campylobacter pylori in antral mucosa. A small group with duodenal ulcers was campylobacter pylori-negative as well as without gastritis signs. Comparing the antrum and corpus gastric mucosa (250 pat.) the antral mucosa was representative for the whole stomach in view of gastritis and campylobacter pylori test, sufficiently for practical use. Between the test methods (culture, urease, microscopy) we favoured the microscopic test.

Adult↗

PubMed1990

[Esophagoscopy and gastroscopy in dogs and cats. Technics and indications].

A report is presented of esophagoscopy and gastroscopy in cats and dogs using flexible endoscopes. Following consideration of the basic equipment, an account is given of patient preparation and anesthesia, topography, investigation technique and normal findings. Diagnostic potential, indications and risks involved are discussed.

Animals↗

PubMed1988

Campylobacter pylori in Swedish patients referred for gastroscopy.

Campylobacter pylori was isolated more often from patient with peptic ulcers and in an age-related manner in a material of 395 consecutive patients referred for gastroscopy. Direct microscopy was done with Gram and Acridine Orange stain and found too insensitive for practical use. All patients were investigated serologically with an enzyme immunoassay which showed excellent correlation with positive cultures for C. pylori. The findings were discussed, and the enzyme immunoassay, with a negative predictive value of 0.99, was found to be a valuable tool for primary screening of patients suspected of being carriers of C. pylori.

Adolescent↗

PubMed1989

[Screening for upper G-I tract cancer by gastroscopy in a 2,000 suspected population].

Mass screening for upper G-I tract cancer was performed by Qin's occult blood bead detector from Nov. 1986 to Apr. 1987 in Yangzhong county, Jiansu province. Of the examined subjects, 2,000 were positive for occult blood. There were 887 males and 1,113 females. The ages ranged from 23 to 75 years, 58.2% were over 40 years. Gastroscopic examinations were performed for all the positive subjects. Sixty-four patients with G-I tract cancers were discovered by gastroscopy with detection rate of 3.2%. Of these 64 patients, 19 had cancer of esophagus, 27 cancer of gastric cardia and 19 gastric cancer in which one patient had double primary cancers with 65 foci. In this series, there were 65.6% early cancers. It may be concluded that the occult blood test in cancer screening had definite value in early detection of the upper G-I tract cancer. The authors suggest that annual test with this bead detector be done for the adult male.

Adult↗

PubMed1989

Campylobacter pylori in patients undergoing gastroscopy at Goroka Base Hospital.

Biopsy specimens were taken from intact areas of antral mucosa in 53 consecutive highlanders presenting for gastroscopy. Spiral or curved bacilli were demonstrated in 31 patients (58%). Campylobacter pylori was cultured from 17 patients (32%). The bacteria were present in 16 (76%) of the 21 patients with gastric ulcer. Histological studies carried out in 25 patients showed gastritis in 21 (84%) and the bacteria were present in all 8 cases of active chronic gastritis and in 5 of 13 cases (38%) of chronic gastritis. These results suggest that infection may play an important role in the aetiology of gastritis and gastric ulcer in Papua New Guinea.

Adult↗

PubMed1979

[Testing antacid with intragastric Ph measurements and gastroscopy].

In connection with the testing of an antacid in form of a suspension, pH-measurement and gastroscopy are carried out in the same 11 patients. Essential criteria of the efficacy of an antacid are its buffering capacity and its retention in the stomach as a mechanical protective for the gastric mucosa. The Talcid suspension tested in this way showed a good period of stay in the stomach, often exceeding the period of acid-binding capacity. Compared with bicarbonate, its buffering period is about twice as long above pH 4.5 and about 2 1/2 times as long at lower pH's.

Antacids↗

PubMed1988

[Routine gastroscopy before cholecystectomy].

We are of the opinion that the investigation of the upper gastrointestinal tract must precede an elective cholecystectomy. In a prospective study the value of preoperative oesophagogastroduodenoscopy preceding elective cholecystectomy is considered. 589 gastroscopies were performed in our endoscopy unit on 960 patients coming to elective gallbladder surgery. Only in 56% of patients we detected no abnormalities. Our plan of therapy was changed in 113 patients (11.7%). 11 patients were discharged after conservative medical therapy (1.1%), in 31 cases simultaneous procedures were performed (3.2%). After additional medical treatment 71 patients came to elective cholecystectomy (7.4%).

Cholecystectomy↗

PubMed1987

[Clinical study and gastroscopy of biliary gastritis following gastric resection and Roux-en-Y anastomosis].

Between 1981 and 1985, seven patients (mean age 44 years) underwent surgery for benign gastroduodenal ulcer in the Department of Surgery. Cantonal Hospital, Fribourg, Switzerland. Surgical indications were a double subcardial and prepyloric ulcer recurring after medical treatment, a duodenal and jejunal anastomotic ulcer after gastroenterostomy, two duodenal ulcers which recurred after vagotomy, and three perforated ulcers (subcardial, prepyloric, duodenal). All patients underwent two-thirds gastrectomy with a Roux-en-Y loop. Clinical investigations and gastroscopy were performed 1-5 years postoperatively. Clinical results were excellent in 5 cases (Visick 1), good in one (Visick 2), and moderate in one (Visick 3). Symptoms and signs associated with biliary gastritis were found as follows: vomiting 1 patient; epigastric pain 1 patient; weight loss 1 patient; anemia 1 patient. No bile staining was seen in any patient. Gastric biopsy demonstrated a normal mucosa in 2 patients and gastritis in 5 patients. Roux-en-Y gastrectomy gives satisfactory results in certain benign gastroduodenal ulcer situations. Perianastomotic and gastric stump gastritis may exist without biliary reflux.

Adult↗

PubMed1979

Premedication for gastroscopy. A comparative study of diazepam, dixyrazine, and placebo.

In a study of 52 consecutive out-patients the effects of diazepam and dixyrazine were compared with each other and with placebo as premedication for elective gastroscopy. All patients also received topical lidocaine and intravenous administration of propantheline bromide immediately before the examination. No difference was found between diazepam and dixyrazine, but they were both significantly superior to placebo in relieving anxiety, retching, and eructations.

Adult↗

PubMed1985

[Gastroscopy in the rat].

A method is described for gastroscopic examination of the rat using a flexible bronchoscope. Endoscopy is performed under ether anesthesia and endotracheal intubation. Gastroscopies of 400 animals demonstrated, that this method is simple, highly sensitive and specific, and carries a low risk. It seems to be well suited for use in experimental gastroenterology.

Animals↗

PubMed1979

[The value of fiber gastroscopy and targeted gastrobiopsy in the diagnosis of stomach ulcers and tumors].

In 2,000 patients the fiber-gastroscopic and bioptic findings were tested with the help of control examinations, results of operations and course observations. Here the fibergastroscopic diagnosis tumour was confirmed in 89.4%. 13 times a wrong diagnosis of tumour was made. Here different substrates were in question (ventricular ulcers, polypous hyperblastic mucous membrane and others). 11 carcinomas were gastroscopically not recognized as tumour. In 25 cases (20%) of the histological investigation of bioptically taken tissue did not result in a confirmation of the fiber-gastroscopic diagnosis of tumour. But 19 times of them the histology was falsely negative. The supplementation of the gastroscopy by biopsy resulted in a right diagnosis in 93.6%. By control examinations a further increase of the accuracy to 96.8% could be reached.

Biopsy↗

PubMedDate not supplied

[Use of metoclopramide in the preparation of patients over 75 for gastroscopy].

The Primperan which has strong antiemetic properties, is suggested to be utilised in premedication before gastroscopy in patients over 75 years old, on account of its lower respiratory depression activity than diazepam, currently used in such occasion. Thirty minutes before starting endoscopy, 20 mg of Primperan (2 ampules) are administered intravenously to the patients. In 15 patients, the results were excellent characterized by a lack of nausea and anxiety, and a very good tolerance.

Age Factors↗

PubMed1981

[Hepatitis B antigen in patients undergoing gastroscopy (author's transl)].

497 patients undergoing gastroscopy were tested for RIA for HBs antigen, HBs antibody and HBc antibody. In 21.9% of these patients (women 19.6%, men 23.3%) one of these tests was positive. The high frequency of positive HBc antibody is remarkable. 7% of our patients (women 7.8%, men 6.3%) were HBs antigen positive and, therefore, a source of infection for doctors and nurses of an endoscopic unit. The results are comparable with studies from other units reported in the literature.

Adult↗