Favism in an English-born child.
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HbA1 was determined in 15 G-6-PD-deficient subjects during a hemolytic crisis with hemoglobinuria due to ingestion of fresh fava beans. The same G-6-PD-deficient subjects were studied again 4 months after the crisis, when they were asymptomatic. 15 normal healthy children served as controls. A statistically significant decrease in HbA1 was observed in the favic subjects during hemolytic crises compared with their values 4 months later and those of the control group.
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Serum GOT, GPT, gamma-GT and GLDH were determined in 15 G-6-PD-deficient subjects during a hemolytic crisis and hemoglobinuria due to ingestion of fresh fava beans. The same G-6-PD-deficient subjects were studied again 2 months after the crisis, when they were asymptomatic. 15 normal healthy children served as controls. A statistically significant increase, above normal, in serum GOT, GLDH and gamma-GT was observed in the favic subjects during the crisis. All the values reverted to normal in the asymptomatic period.
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