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At least 163 records · Page 9Linked to original sources
PubMed1995

[Transcranial Doppler ultrasound: effects of intravenous anesthetics in neurosurgical patients].

AIM: Although adverse effects on cerebral blood flow have been reported, intravenous anaesthetic and sedative agents are often used in neurosurgical patients. Monitoring of these effects by transcranial Doppler sonography remains a questionable procedure as long as the cross-sectional area of the insonated basal cerebral arteries is unknown. This study should evaluate the effects of thiopental, propofol, midazolam and alfentanil on flow velocities and "vessel cross-sectional area" (proportional to the reflected Doppler signal power) measured by transcranial Doppler sonography. METHOD: 19 patients with severe cerebral lesions (Glasgow Coma Scale < 6) were investigated. They were hyperventilated and sedated with fentanyl and flunitrazepam. The Doppler probe was fixed to the temporal bone and focussed to the middle cerebral artery of the more severely lesioned side. Baseline values of flow velocities and vascular cross-sectional area were measured. If routine nursing procedures required a deeper degree of sedation, either thiopental 2.5 mg/kg, propofol 1 mg/kg, midazolam 0.075 mg/kg or alfentanil 0.025 mg/kg were injected intravenously over 30 s. Further measurements were made 60, 120 and 300 s after start of the injection. Mean +/- SD were calculated, statistical evaluation was performed by analysis of variance and paired t-tests using the Bonferroni correction (p < 0.05). RESULTS: The injected agents induced significant decreases of the mean value of flow velocities; the "vessel cross-sectional area" remained unaltered. In some patients paradoxical increases of v were observed. CONCLUSION: The results indicate that intravenous anaesthetic agents are not likely to influence the cross-sectional area of the major basal cerebral arteries. Therefore TCD seems to be a valid tool to monitor the effects of these agents on the cerebral circulation of neurosurgical patients. This is probably of prognostic and therapeutic value.

Adolescent↗
PubMed1999

[Physicists in medicine: Johann Christian Doppler].

It is impossible, nowadays, to imagine modern medical diagnostic without devices that work on the basis of "Dopplers Effect". Within medicine (in medical diagnostic as well as in medical therapy" "Dopplers Effect" is mainly used indirectly, in other words, using the devices based on "Dopplers Effect", due the the gathering of some useful results, but their physics background or direct usage and understanding of this scientific theory are usually left outside. The physical nature of "Dopplers Effect", biographical facts on J.C. Doppler and main ways of "Dopplers Effect" usage are mentioned in the following thesis.

Austria↗
PubMed2003

The influence of flight speed on the ranging performance of bats using frequency modulated echolocation pulses.

Many species of bat use ultrasonic frequency modulated (FM) pulses to measure the distance to objects by timing the emission and reception of each pulse. Echolocation is mainly used in flight. Since the flight speed of bats often exceeds 1% of the speed of sound, Doppler effects will lead to compression of the time between emission and reception as well as an elevation of the echo frequencies, resulting in a distortion of the perceived range. This paper describes the consequences of these Doppler effects on the ranging performance of bats using different pulse designs. The consequences of Doppler effects on ranging performance described in this paper assume bats to have a very accurate ranging resolution, which is feasible with a filterbank receiver. By modeling two receiver types, it was first established that the effects of Doppler compression are virtually independent of the receiver type. Then, used a cross-correlation model was used to investigate the effect of flight speed on Doppler tolerance and range-Doppler coupling separately. This paper further shows how pulse duration, bandwidth, function type, and harmonics influence Doppler tolerance and range-Doppler coupling. The influence of each signal parameter is illustrated using calls of several bat species. It is argued that range-Doppler coupling is a significant source of error in bat echolocation, and various strategies bats could employ to deal with this problem, including the use of range rate information are discussed.

Acceleration↗
PubMed2004

The proposal of noninvasive quantitative diagnostic method of the atherosclerosis and the clarification of organ correlation of atherosclerosis and oxygen metabolism.

The proposal of noninvasive diagnostic method of mechanical degradation of vascular wall is clinically useful and it will be correlated with noninvasive diagnostic method of atherosclerosis. Supersonic Doppler effect sensor has been used to measure blood flow velocity as a noninvasive measuring method. However, it is remain problem whether the output from the Doppler effect sensor really detects the pure blood flow velocity. Theoretically, when the Doppler effect sensor is set perpendicular to the blood flow direction, that is, perpendicular to the blood vessel, the output will correspond to the expansion velocity of blood vessel wall, because it detect the frequency of Doppler shifted supersonic scattered from vascular wall. Previously, on the basis of this concept, using Doppler effect sensor, we showed this method can really detect the deformation velocity of blood vessel wall and it correlates the degradation of elastic property of blood vessel. Furthermore, using this proposed measuring method, atherosclerosis is found to progress correspondingly with the visco-elastic degradation of vascular wall. In this paper, on the basis of our proposed method, the quantitative noninvasive estimation method of the degradation of vascular wall and the progressive degree of atherosclerosis by unique parameter has been proposed. Using this method, the degradation of vascular wall is correlated to the oxygen metabolic function of blood vessel corresponding to the function of oxygen transportation and progression of atherosclerosis. Furthermore, the organ correlation on the atherosclerosis between lower limb and carotid is investigated by this proposed method.

Algorithms↗
PubMed2003

Effects of echo intensity on Doppler-shift compensation behavior in horseshoe bats.

Echolocating horseshoe bats respond to flight-speed induced shifts in echo frequency by adjusting the frequency of subsequent calls. Under natural conditions, Doppler effects may force the frequency of a returning echo several kilohertz above the original emission frequency. By lowering subsequent call frequencies, the bat can return echo frequencies to within a narrow spectral bandwidth to which its highly specialized auditory system is most sensitive. While Doppler-shift compensation (DSC) behavior specifically refers to frequency compensation, other parameters of the returning echo, such as delay, duration, and interaural time and intensity differences have been shown to influence DSC performance. Understanding the nature of these influences has already led to a better appreciation of the neurophysiology of DSC. Here we provide a quantitative analysis of the effects of a prominent feature of the returning echo, its intensity, on DSC performance in horseshoe bats. Although DSC performance generally tolerates echo attenuation up to approximately 40 dB relative to the outgoing emission intensity, a systematic decline in DSC performance can be observed over this range. Generally, the effects of echo attenuation are characterized by a reduction in 1) the overall amount of compensation relative to the size of the shift in echo frequency and 2) the rate at which the bat responds to perceived echo shifts. These effects appear to be the consequence of a systematic shift in the range of echo frequencies capable of inducing DSC behavior. In particular, the reference frequency (the minimum shift in echo frequency that will elicit DSC behavior) appears to be highly sensitive to echo intensity. Every 10-dB reduction in echo intensity shifts the reference upward nearly 250 Hz. Our results indicate that, even at the highest intensity levels, relatively minor changes in echo intensity critically influence frequency compensation during normal DSC. We conclude with a discussion of how these results might impact echolocation behavior of horseshoe bats under natural and experimental conditions.

Adaptation, Physiological↗
PubMed2006

Doppler broadening effect on low-energy photon dose calculations using MCNP5 and PENELOPE.

Recent releases of the MCNP5 and PENELOPE Monte Carlo codes include the transport algorithm and momentum profiles that are necessary for accounting for Doppler broadening in Compton scattering processes. Such improvements might be particularly important in low-energy photon dose calculations. MCPLIB04 and PENDBASE (PENELOPE photon dataset) are based on the EPDL97 library with Compton momentum profiles, while MCPLIB03 and MCPLIB02 are based on the 1970's old library, with MCPLIB03 including the Compton momentum profiles. To isolate the dosimetric effects of Doppler broadening by the transport algorithm and Compton momentum profiles, we varied the choice of the above photon databases, in the same simulation geometry, using either version of MCNP5 or MCNP4 (no Doppler algorithm). We computed dose rate constants and dose distributions for r = 0.2-10 cm from a point source in a 50-cm-diameter sphere of water. Nine discrete energies for primary photon sources were chosen in the range of 10-150 keV. The results from both versions of MCNP with MCPLIB04 agreed with those of PENELOPE within statistical uncertainties (+/-1%) over the entire ranges of energies and radial distances investigated. MCNP5 with either MCPLIB03 or MCPLIB02 yielded almost identical data within statistical uncertainties (+/-1%) over the entire ranges of energies and radial distances investigated. This implies that in spite of the spectral broadening of scattered photons due to the orbital electron motion, the dosimetric effect of Doppler broadening for Compton interactions in water appears to be insignificant in the energy range investigated. The spectral dose analysis with and without the Doppler broadening supported this conclusion.

Algorithms↗
PubMed1984

[Monitoring fetal movements using the Doppler-Fizeau effect with a new apparatus: the Tococinon].

We introduce the Tococinon, which is an apparatus using the Doppler-Fizeau effect. Its purpose is to record fetal movements. The method carries good correlation with ultrasonographic observations of fetal movements. It is more accurate than the patient's own impressions, and can be used from the end of the first trimester until term. The Tococinon makes it possible for the mother to watch her own baby's behaviour and to screen for abnormalities in it. Its development makes it possible for us to foresee other studies on different types of movement and to attempt to correlate these with some pathological states.

Adolescent↗
PubMed1997

[Transcranial doppler sonography. Effect of sevoflurane in comparison to isoflurane].

METHODS: Using transcranial Doppler sonography (TCD), we studied the effects of sevoflurane compared to equipotent doses of isoflurane on blood-flow velocity in the middle cerebral artery (MCA) before, during, and after general anaesthesia. In random order, 30 patients received sevoflurane (n = 15) or isoflurane (n = 15) given in stepwise-increasing doses of 0.5, 1.0, and 1.5 MAC in oxygen/air (FiO2 = 0.5). Oxygen/air was then replaced by oxygen/nitrous oxide 33%/65% with decreasing doses (1.5, 1.0, 0.5 MAC) of sevoflurane or isoflurane. During each step, ventilation was controlled to provide first normocapnia (end-tidal pCO2 = 38 mmHg) and then hypocapnia (end-tidal pCO2 = 27 mmHg). MCA blood-flow velocity and pulsatility, arterial blood pressure, heart rate, and body temperature were recorded simultaneously at the end of each period. For statistical analysis, within-group comparison was made by one-way ANOVA. Differences between groups were determined by two-way analysis of variance. Age, weight, and height of the patients were compared using Student's t-test; P < 0.05 was considered significant. RESULTS: Groups were comparable regarding age, weight, and height. TCD parameters were not significantly changed by increasing doses of sevoflurane or isoflurane given in oxygen/air when compared to the awake data. However, increasing MCA blood-flow velocity was found with decreasing doses of sevoflurane or isoflurane given in oxygen/nitrous oxide (P < 0.05 for 0.5 MAC, normoventilation) without intergroup, differences. In both groups, hyperventilation always decreased MCA blood-flow velocity. CONCLUSIONS: We conclude from our TCD data that equipotent doses of sevoflurane and isoflurane comparably affect cerebral perfusion, especially when nitrous oxide is given simultaneously.

Adolescent↗
PubMed1985

Determination of the second order doppler shift of iron in myoglobin by Mössbauer spectroscopy.

We have performed Mössbauer absorption experiments on a sample of deoxygenated myoglobin crystals from 5 K to 280 K. With two series of measurements, one with the source and sample at the same temperature and the other with the source always at 298 K, we are able to extract information from the second-order Doppler effect in the sample. Simple models consistent with a description of myoglobin with low lying electronic states which are thermally populated above 40 K indicate that the Debye temperature of myoglobin is 220 K, in agreement with measurements using the Lamb-Mössbauer factor. The second-order Doppler effect is proportional to the square of the velocity of the motion. We are unable to see any indication of protein specific motion from the second-order Doppler effect, thereby indicating that protein specific motions are relatively slow.

Animals↗