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PubMed1997

A critique of fixed and progressive ratio schedules used to examine the neural substrates of drug reinforcement.

This paper is a critique of fixed and progressive ratio schedules used to examine the neural substrates of cocaine reinforcement. The discussion focuses on problems encountered while examining the effects of neurotoxic lesions and pharmacological pretreatments on cocaine reinforcement. We review the theoretical and interpretational problems associated with the use of the fixed ratio (FR) schedules that have been used in the majority of studies, and we conclude that rate of drug intake cannot directly address the issue of increased or decreased reinforcer efficacy. The progressive ratio (PR) schedule offers some advantages over FR schedules, although it is now clear that the same implementation cannot be applied across all drug classes. It is likely that the motivation to self-administer psychostimulant vs. opiate drugs is qualitatively different. We conclude that there is no single schedule that can quantify all aspects of drug reinforcement and that behavioral paradigms will need to be adapted according to the particular question under study.

Animals↗
PubMed2001

What is a memory system? Horel's critique revisited.

J.A. Horel's critique of what he termed "the hippocampal memory hypothesis" turns out, 23 years later, to have been remarkably discerning and prophetic. There is now an overwhelming weight of evidence to confirm his four key proposals: that selective destruction of the hippocampus or fornix does not produce dense global amnesia; that the effects of hippocampal or fornix lesions are not primarily a memory impairment, but an impairment in processing spatial information; that damage to the anterior temporal stem is part of the explanation of dense temporal lobe amnesia; and that the interaction of temporal cortex with prefrontal cortex is essential in memory. This review summarizes the modern evidence that reinforces each of these four proposals. A final section argues that, not only in the case of the hippocampus but also in the case of other temporal and frontal cortical areas that are involved in normal memory, the concept of a "memory system" is harmful.

Amnesia↗
PubMed1997

The misconstruction of critical medical anthropology: a response to a cultural constructivist critique.

Since its emergence over a decade ago as a distinct theoretical framework, critical medical anthropology (CMA) has engaged in debate and dialogue with various other perspectives within medical anthropology, particularly clinical anthropology, medical ecology, and, to a lesser degree, postmodernism. While at least two genres of CMA have emerged, both of which are involved in a dialogue with each other, proponents of other perspectives often misread or "misconstruct" the agenda of CMA as both a theoretical framework and a strategy for health activism. This essay in particular critiques this process among proponents of the interpretative or cultural constructivist perspective. On a positive note, however, I urge critical medical anthropologists and cultural constructivists within medical anthropology to enter into a dialogue with each other because their two perspectives, despite the presence of obvious epistemological differences, share commonalities.

Anthropology↗
PubMed1998

Wealth, equity and health care: a critique of a "population health" perspective on the determinants of health. Critical Social Science Group.

In this paper we examine the recent ascendancy of a "population health" perspective on the "determinants of health" in health policy circles as conceptualized by health economists and social epidemiologists such as Evans and Stoddart [Evans and Stoddart (1990) Producing health, consuming health care. Social Science & Medicine 31(12), 1347 1363]. Their view, that the financing of health care systems may actually be deleterious for the health status of populations by drawing attention away from the (economic) determinants of health, has arguably become the "core" of the discourse of "population health". While applauding the efforts of these and other members of the Canadian Institute for Advanced Research for "pushing the envelope", we nevertheless have misgivings about their conceptualization of both the "problem" and its "solutions", as well as about the implications of their perspective for policy. From our critique, we build an alternative point of view based on a political economy perspective. We point out that Evans and Stoddart's evidence is open to alternative interpretations--and, in fact, that their conclusions regarding the importance of wealth creation do not directly reflect the evidence presented, and are indicative of an oversimplified link between wealth and health. Their view also lacks an explicit substantive theory of society and of social change, and provides convenient cover for those who wish to dismantle the welfare state in the name of deficit reduction. Our alternative to the "provider dominance" theory of Evans and Stoddart and colleagues stresses that the factors or forces producing health status, which Evans and Stoddart describe, are contained within a larger whole (advanced industrial capitalism) which gives the parts their character and shapes their interrelationships. We contend that this alternative view better explains both how we arrived at a situation in which health care systems are as costly or extensive as they are, and suggests different policy avenues to those enunciated by Evans, Stoddart and their confrères.

Canada↗
PubMed1999

A critique of seven assumptions behind psychological trauma programmes in war-affected areas.

Programmes costing millions of dollars to address 'posttraumatic stress' in war zones have been increasingly prominent in humanitarian aid operations, backed by UNICEF, WHO, European Community Humanitarian Office and many nongovernmental organisations. The assumptions underpinning this work, which this paper critiques with particular reference to Bosnia and Rwanda, reflect a globalisation of Western cultural trends towards the medicalisation of distress and the rise of psychological therapies. This paper argues that for the vast majority of survivors posttraumatic stress is a pseudocondition, a reframing of the understandable suffering of war as a technical problem to which short-term technical solutions like counselling are applicable. These concepts aggrandise the Western agencies and their 'experts' who from afar define the condition and bring the cure. There is no evidence that war-affected populations are seeking these imported approaches, which appear to ignore their own traditions, meaning systems, and active priorities. One basic question in humanitarian operations is: whose knowledge is privileged and who has the power to define the problem? What is fundamental is the role of a social world, invariably targeted in today's 'total' war and yet still embodying the collective capacity of survivor populations to mourn, endure and rebuild.

Adolescent↗
PubMed1998

The use of intravenous opioids to provide analgesia in critically ill, premature neonates: a research critique.

The intravenous (i.v.) administration of opioids to neonates is a common method of providing analgesia in the intensive care setting. This paper reviews and critiques the studies that have investigated this intervention. The studies are grouped into four major areas: pharmacokinetic studies; i.v. opioids for anesthesia; i.v. opioids for sedation or analgesia in mechanically ventilated neonates; and cardiorespiratory effects of i.v. opioids. An attempt is made to synthesize current knowledge about the analgesic effects and side effects associated with the use of i.v. opioids in neonates. The intent is to stimulate additional research on the management of neonatal pain using opioid analgesics.

Analgesics, Opioid↗
PubMedDate not supplied

The Asgaard project: a task-specific framework for the application and critiquing of time-oriented clinical guidelines.

Clinical guidelines can be viewed as generic skeletal-plan schemata that represent clinical procedural knowledge and that are instantiated and refined dynamically by care providers over significant time periods. In the Asgaard project, we are investigating a set of tasks that support the application of clinical guidelines by a care provider other than the guideline's designer. We are focusing on the application of the guideline, recognition of care providers' intentions from their actions, and critique of care providers' actions given the guideline and the patient's medical record. We are developing methods that perform these tasks in multiple clinical domains, given an instance of a properly represented clinical guideline and an electronic medical patient record. In this paper, we point out the precise domain-specific knowledge required by each method, such as the explicit intentions of the guideline designer (represented as temporal patterns to be achieved or avoided). We present a machine-readable language, called Asbru, to represent and to annotate guidelines based on the task-specific ontology. We also introduce an automated tool for the acquisition of clinical guidelines based on the same ontology, developed using the PROTEGE-II framework.

Artificial Intelligence↗
PubMed2001

A critique of the neuroecology of learning and memory.

Recent years have seen the emergence of neuroecology, the study of the neural mechanisms of behaviour guided by functional and evolutionary principles. This research has been of enormous value for our understanding of the evolution of brain- and species-specific behaviour. However, we question the validity of the neuroecological approach when applied to the analysis of learning and memory, given its arbitrary assumption that different 'problems' engage different memory mechanisms. Differences in memory-based performance in 'natural' tasks do not prove differences in memory capacity; similarly, differences in the use of memory in the natural environment do not provide a sound basis for expecting differences in anatomical structures that subserve learning and memory. This critique is illustrated with examples taken from the study of the neurobiology of food storing and song learning in birds.

Journal Article↗
PubMedDate not supplied

The National Weight Control Registry: a critique.

This article is a critique of the claim that the National Weight Control Registry provides data showing that a significant number of adults in the United States have achieved permanent weight loss. We believe that promoting calorie-restricted dieting for the purpose of weight loss is misleading and futile. We advocate the adoption of a health-at-every-size (HAES) approach to weight management, focusing on the achievement and maintenance of lifestyle changes that improve metabolic indicators of health.

Diet, Reducing↗
PubMed1997

Fear and envy: sexual difference and the economies of feminist critique in psychoanalytic discourse.

This essay examines Freud's construction of a mythical moment during early childhood, in which differences between male and female sexual identities are said to originate. It focuses on the way in which Freud divides fear and envy between the sexes, allocating the emotion of (castration) fear to men, and that of (penis) envy to women. On the one hand, the problems of this construction are pointed out, but on the other hand, it is shown that even a much-maligned myth may still provide food for thought. Then, four critiques of Freud which have been articulated by prominent feminist psychoanalysts -- Karen Horney, Nancy Chodorow, Luce Irigaray, and Jessica Benjamin -- are presented, as well as the alternative visions of sexual identities which these thinkers have developed. The basic metaphors or economies guiding these visions of sexual difference are appraised in terms of their breadth and depth, with particular reference to their ability to acknowledge and integrate the presence of fear and envy as passions which are evoked but also repressed in the face of sexual difference. ...

Feminism↗
PubMed1995

Medical discourse in religious controversy: the case of the critique of "enthusiasm" on the eve of the Enlightenment.

Medicine is not only a cultural system of its own. It also performs specific roles in the broader culture of society at large. This article examines the role of medical arguments in the critique of "enthusiasm" on the eve of the Enlightenment. The enthusiasts, who claimed to prophesy and to have direct divine inspiration, were increasingly seen in the seventeenth century as melancholics. With the decline of humoral medicine, however, the account of melancholic disturbances--including enthusiasm--that was offered tended to be chemical, mechanistic, and clearly corpuscular. Protestant ministers, in adopting such an account of enthusiasm, also adopted a strict distinction between the realm of the mind (to which true prophecy belonged) and that of the body (in which they located the phenomena of enthusiasm). Such a distinction served in turn to demarcate more specifically the limits between the clerical and medical professions. Yet in relegating the treatment of enthusiasts to the physicians, rather than seeing the enthusiasts as heretics, the ministers stood in danger of relying too much on a secular profession and secular arguments, thus paving the way to a more general secularization of the ideological basis of the social order.

Europe↗
PubMed2005

Acetic acid vapor: 2. A statistical mechanical critique of vapor density experiments.

A statistical mechanical model is used to critique vapor density experiments on acetic acid. The model suggests that the differences in the standard enthalpy of dissociation of acetic acid dimer reported in the literature lie mainly in the interpretation of the data and not in the data itself. If a uniform and plausible interpretative framework is adopted, the discrepancies largely disappear.

Journal Article↗
PubMed2001

Ethnographic critique and technoscientific narratives: the old mole, ethical plateaux, and the governance of emergent biosocial polities.

A reading of the puzzle novel Vienna Blood, by Adrian Mathews, is juxtaposed to three ethnographic sketches of contemporary ethical plateaus or domains of ethical challenge--the challenges of informed public consent to new technologies, the seductions to do whatever is medically possible (sometimes at the expense of quality of life or the good death'). and the power of money in driving the biotechnological industries. Vienna Blood deals with precautionary germplasm modification and chemical camouflage justified as protection against ethnically-targeted biological warfare, and touches on a series of technologies such as new reproductive technologies, genetic engineering, and cryptographic attacks and defenses, as well as the ability to evade regulatory controls. Such technoscientifically informed novels are useful as cautionary tales, in exploring the complexity and interaction among new technologies, and the phantasmagoria that help drive new technologies. They are not so good at thinking through institutional development: a challenge for ethnography and new social theory. Ethnography, like novels, can function as checks on the mechanisms of abstraction and universalization that frequently bedevil the non-anthropological, non-cross-culturally or cross-temporally comparative, social sciences. Questions are raised about new or emergent biosocialities, forms of governance, and forms of cultural critique.

Advertising↗
PubMed2002

Duty or dream? Edwin G. Conklin's critique of eugenics and support for American individualism.

This paper assesses ideas about moral and reproductive duty in American eugenics during the early twentieth century. While extreme eugenicists, including Charles Davenport and Paul Popenoe, argued that social leaders and biologists must work to prevent individuals who were "unfit" from reproducing, moderates, especially Edwin G. Conklin, presented a different view. Although he was sympathetic to eugenic goals and participated in eugenic organizations throughout his life, Conklin realized that eugenic ideas rarely could meet strict hereditary measures. Relying on his experience as an embryologist, Conklin instead attempted to balance more extreme eugenic claims - that emphasized the absolute limits posed by heredity - with his own view of "the possibilities of development." Through his critique he argued that most human beings never even begin to approach their hereditary potential; he moderated his own eugenic rhetoric so that it preserved individual opportunity and responsibility, or what has often been labeled the American Dream.

Eugenics↗
PubMed1998

Rejoinder to Mordock's critique of the Fort Bragg Evaluation Project: the sample is generalizable and the outcomes are clear.

The Fort Bragg Evaluation Project (FBEP) showed that children in a well implemented and expensive continuum of care had no better clinical outcomes than those experiencing more traditional and fragmented services. In an article published in this journal that was critical of the evaluation, Mordock argued that the FBEP results be viewed with skepticism because of what he perceived to be methodological, design, measurement, and analytic failures of this study. We think it is important to respond to Mordock's critique since it contributes to the great reluctance to seriously consider the study's findings and their implications.

Adolescent↗
PubMed2004

Ethnic differences using behavior rating scales to assess the mental health of children: a conceptual and psychometric critique.

This article reviews the literature on using behavior-rating scales to assess the mental health of children from different ethnic groups in the United States. Particular emphasis is placed on children referred to child welfare and juvenile justice systems. Differences between categorical and dimensional classification, as well as broadband versus narrowband classification approaches are discussed. Sources of potential bias and the best available methods used to assess ethnic group differences in ratings scales are presented. Finally, the extent to which behavior rating scales have been examined for measurement equivalence is critiqued and directions for future research are forward.

Child↗
PubMed2004

A review and critique of the Sexual Experiences Questionnaire (SEQ).

This paper reviews and critiques the Sexual Experiences Questionnaire (SEQ), "... a self-report inventory representing the first attempt to assess the prevalence of sexual harassment in a manner that met traditional psychometric standards" (Fitzgerald, Gelfand, & Drasgow, 1995, p. 427). Widely used by its developers and others as a measure of sexual harassment, the SEQ is not a finished product, has a number of problems, and has weak psychometric properties. Because of inconsistencies (e.g., in time frame, number of items, wording of items), the SEQ lacks the advantages of standardized measures, such as the ability to assess changes over time. It defines sexual harassment very broadly, having the effect of distorting findings about sexual harassment. Most importantly, it is not clear what or whose definition of sexual harassment the SEQ assesses.

Female↗
PubMed1983

A critique of Plomin and Foch's "A Twin Study of Objectively Assessed Personality in Childhood".

Plomin and Foch's (1980) study of objectively assessed personality in childhood is critiqued on five points: (a) conceptual validity of the measures, (b) stability of the measures for the population age range, (c) comparability of populations, (d) accuracy of literature review, and (e) appropriate interpretation of broad heritability data. The Plomin and Foch study contains major errors; it is theoretically and methodologically flawed. Their report is especially significant because it is representative of problems critical to the study of the genetic correlates of personality.

Child↗