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PubMed2005

Radiographic human identification using bones of the hand: a validation study.

The 1993 Supreme Court case Daubert v. Merrell-Dow Pharmaceuticals, Inc. underscores the importance of validating forensic science techniques. This research examines the validity of using posterior-anterior radiographs of the hand to make positive identifications of unknown human remains. Furthermore, this study was constructed to satisfy the requirements of Daubert's guidelines of scientific validity by establishing a standard methodology for hand radiograph analysis, testing the technique, and noting rates of error. This validation study required twelve participant examiners from the forensic science community, working independently, to attempt to match 10 simulated postmortem radiographs of skeletonized hands to 40 simulated antemortem radiographs of fleshed cadaver hands. The overall accuracy rate of the twelve examiners was 95%, while their collective sensitivity and specificity were 95% and 92%, respectively. However, the accuracy of each examiner was related to the amount of radiological training and experience of the observer. Six Ph.D. forensic anthropologists and four experienced forensic anthropology graduate students correctly identified all the matches. Participant examiners noted bone morphology, trabecular patterns of the proximal and middle phalanges, and distinctive radiopaque and radiolucent features as the anatomical features that aided the identification process. The hand can be an important skeletal element for radiographic positive identification because it contains 27 individual bones for comparative analysis.

Aged↗
PubMed1972

National library of medicine regional medical library program.

The National Library of Medicine is charged with the development and management of a National Biomedical Communications Network. The Regional Medical Library Program is a forerunner of such a network; the product and institutions involved will be critical elements in its evolution. The immediate objective of the RMLP, the facilitation of biomedical information transfer, presents a logistical problem requiring substantial commitment from the health sciences community and extensive cooperation among libraries in each region.

Journal Article↗
PubMed2006

[Awards to Hajime Hoshi dedicated from Germany].

In the Hajime Hoshi Memorial Exhibit Hall of Hoshi University, many awards dedicated to H. Hoshi from Germany are displayed. Hoshi made a donation amounting to about 20 millions dollars to the distressed chemistry science community of Germany just after the 1st World War. The Hoshi fund gave the scientific society hope to recover, and deeply impressed and delighted the German people. The awards to Hoshi dedicated from Germany strongly reflect the hot spirit of Japan-Germany cultural exchange. The present study investigates the details of the awards.

Awards and Prizes↗
PubMed1992

Debates, divisions, and decisions: recombinant DNA advisory committee (RAC) authorization of the first human gene transfer experiments.

Possibly the most far-reaching, controversial research currently being conducted in the international biological science community involves human gene therapy experimentation. In this paper, I report the dynamics of the political process which ultimately found the Recombinant DNA Advisory Committee (RAC) of the National Institutes of Health approving for the first time protocols of this genre. A full appreciation of the policy-making dialogue shows that significant participants perceived the process from very different vantage points regarding the way in which the American political system works and the way in which it ought to work. I argue that, if we are to understand how the RAC should proceed in orchestrating a human gene therapy policy agenda, then we must flesh out and critically analyze these competing vantage points. To that end, I postulate seven possible "action models" for characterizing how protocol assessments of the type at issue might be developed given the nature of our politics, reaching the conclusion that one of these models holds out the most promise for synthesizing efficaciously the key factors involved. In conclusion, I discuss how the RAC might profitably employ this preferred strategy in these and other cases.

Advisory Committees↗
PubMed1990

Nonfracture-associated fatal fat embolism in a case of child abuse.

Fatal fat embolism is usually thought of as a sequel to long-bone fracture, although cases secondary to soft tissue injury and atraumatic conditions have been infrequently reported. In this case of a two-year-old child-abuse victim who sustained multiple blunt traumatic injuries without skeletal fractures, pulmonary and systemic (brain and kidney) fat emboli were identified. At autopsy, all thoracic and abdominal viscera were intact; cranial contents exhibited only diffuse symmetrical petechial hemorrhages of the white matter. Because of the severe and widespread nature of soft tissue hemorrhage, and the absence of a grossly discernible cause of death, fat embolism was suspected. Using a combination of frozen section with oil red O staining and formalin-fixed osmium stained tissues, the immediate cause of death was determined to be diffuse fat embolism. Review of the literature reveals a pathophysiologic basis for fat embolism in the absence of fracture, both as a consequence of an acute increase in local pressure at the site of trauma and an alteration of the emulsification of blood lipids during shock. In light of these findings, we present this case to remind the forensic science community to consider fat embolism as the cause of death in cases of blunt-force injury without fracture.

Cause of Death↗
PubMed1987

Searching for patterns in the MeSH vocabulary.

NLM revises its MeSH vocabulary annually to reflect changes in biomedical literature and the health sciences community. This study tested two hypotheses about NLM's MeSH vocabulary. The first is that new terms are added to MeSH when their broader terms have an increased number of postings. One examination compared the number of postings for the broader terms of new and existing terms in the current MEDLINE file; the other compared them over time. No significant statistical difference was found in either case. A second hypothesis--that there is a relationship between the patterns of MEDLINE indexing and searching and the organization of the MeSH tree structure--was tested by comparing the distribution of searched terms in the MeSH trees with the distribution of all terms. It was found that certain trees are searched more often than could be predicted by the overall term distribution, while others are searched less frequently than expected. In summary, (1) new terms cannot be predicted by the increase in postings of existing terms, and (2) searchers' and indexers' use of the terms' tree structure does not correlate with the terms' distribution in the MeSH trees.

Abstracting and Indexing↗
PubMed1987

Automated gunshot residue particle search and characterization.

The main disadvantage to gunshot residue (GSR) particle analysis utilizing scanning electron microscope/energy dispersive X-ray (SEM/EDX) instrumentation has been the excessive operator time required for search and identification. This study uses an automated particle search and characterization program for unattended GSR search and identification. This system allows for automatic matrix search, particle sizing, chemical typing, and spectral aquisition with subsequent storage of data to disk for later operator review and verification. This work describes various aspects of the program, determines appropriate parameters adequate for both unique and characteristic GSR particle identification, and evaluates the reliability of data obtained. Samples are collected via the tape lift method from test-firings of .38, .32, .25, and .22 caliber handguns at time after firing intervals of 0 to 6 h. Unique GSR particles are consistently and correctly identified by this method on tape lift samples taken up to 4 h after firing. False positive results of unique GSR particles are not encountered on control handblank samples. This technique appears to provide the forensic science community with an operator-free method of reliable GSR particle search and an improved analyst-time-per-case ratio.

Electron Probe Microanalysis↗
PubMed1994

Schistosomiasis research and the European Community.

Schistosomiasis research within the framework of the Commission of the European Communities 'Science and Technology for Development' (CEC/STD) Programme is targeted at three specific problems: diagnosis of infection and disease; the dynamics of transmission, immunity, and morbidity; and the need for improved tools and strategies for control. Several important advances have been made over the past decade. Improved methods of diagnosis by detection of circulating antigens are in an advanced stage of development and have already undergone field trials in several epidemiological settings. Treatment and reinfection studies combined with immunological observations have allowed the elucidation of possible mechanisms leading to acquired resistance, and have shown that repeated chemotherapy with praziquantel can substantially reduce morbidity. Other projects have studied the epidemiological and ecological determinants of transmission, infection and disease in various endemic situations and also in newly established, epidemic foci where remarkable observations on chemotherapeutic responses were made. Important advances have been made towards the development of a vaccine. The glutathione-S-transferases of the major species of schistosomes have been cloned, sequenced and expressed, and their biological function studied. In a variety of vaccine formulations and animal systems GST has been able to confer protection against infection and to reduce worm fecundity. GST and a series of other crude and defined antigens have been evaluated with varying results in Schistosoma japonicum and S. bovis in cattle. Much work has yet been done, however. Recommendations as to possible future directions for research are provided.

Clinical Trials as Topic↗
PubMed1997

Aging of bitemarks: a literature review.

The aging of bitemarks through the subjective interpretation of visual signs has created an area of controversy in the forensic science community. The healing dynamics of these bite wounds has been insufficiently studied and is poorly understood. A review of the literature related to bitemark aging was undertaken in an effort to summarize the currently published information on this misunderstood subject.

Adult↗
PubMed2000

Community-based curriculum in psychiatric nursing science.

As community-based health care delivery is now a prominent feature of the health care system in South Africa, nursing curricula are being challenged to prepare student nurses for community-based nursing roles and responsibilities. The purpose of this study was to describe guidelines for a community-based curriculum in psychiatric nursing science for a nursing college in KwaZulu-Natal. A qualitative, quantitative, exploratory, descriptive and contextual design was employed. To reach the purpose of the study, a situational analysis was done in three phases to identify the principles for a community-based curriculum for psychiatric nursing science. PHASE I: A document analysis of relevant government policies and legislation. PHASE II: Statistics from psychiatric hospitals and community psychiatric clinics. PHASE III: Focus group interviews with nurse educators and literature control and conceptual framework. The principles obtained from the three phases were used to formulate the guidelines for a community-based curriculum in psychiatric nursing science. (PHASE IV): Eight guidelines with practical implications are described for the implementation of a Community-based curriculum in Psychiatric Nursing Science.

Attitude of Health Personnel↗
PubMed2006

Developing a virtual community for health sciences library book selection: Doody's Core Titles.

PURPOSE: The purpose of this article is to describe Doody's Core Titles in the Health Sciences as a new selection guide and a virtual community based on an effective use of online systems and to describe its potential impact on library collection development. SETTING/PARTICIPANTS/RESOURCES: The setting is the availability of health sciences selection guides. Participants include Doody Enterprise staff, Doody's Library Board of Advisors, content specialists, and library selectors. Resources include the online system used to create Doody's Core Titles along with references to complementary databases. BRIEF DESCRIPTION: Doody's Core Titles is described and discussed in relation to the literature of selection guides, especially in comparison to the Brandon/Hill selected lists that were published from 1965 to 2003. Doody's Core Titles seeks to fill the vacuum created when the Brandon/Hill lists ceased publication. Doody's Core Titles is a unique selection guide based on its method of creating an online community of experts to identify and score a core list of titles in 119 health sciences specialties and disciplines. RESULTS/OUTCOME: The result is a new selection guide, now available annually, that will aid health sciences librarians in identifying core titles for local collections. EVALUATION METHOD: Doody's Core Titles organizes the evaluation of core titles that are identified and recommended by content specialists associated with Doody's Book Review Service and library selectors. A scoring mechanism is used to create the selection of core titles, similar to the star rating system employed in other Doody Enterprise products and services.

Book Selection↗
PubMed2001

Commitment of the National Institute of Environmental Health Sciences to community-based participatory research for rural health.

The National Institute of Environmental Health Sciences (NIEHS) is the leading biomedical research institution in the United States whose mission is to support research that seeks to understand how environmental exposures affect human health. NIEHS possesses a longstanding interest in the health effects of agrochemical and other environmental exposures in rural America, including pesticides, to farmers and their families and to migrant farmworkers and their families. In recent years, NIEHS has begun augmenting traditional basic science investigations with innovative programs that translate findings from the laboratory to affected populations. It is through community-based participatory research that NIEHS strives to advance the public health field by fostering the development of culturally relevant interventions that will reduce exposures to environmental contaminants and the risk of environmentally induced disease. In this article, we describe the translational research program at NIEHS as it relates to the NIEHS mission and highlight activities pertinent to the health of rural communities, especially underserved populations. We provide an overview of NIEHS-supported projects addressing health concerns of Native American and rural African-American communities in addition to farmworkers. We conclude with a discussion of future plans for community-based participatory research at NIEHS.

Agriculture↗
PubMed2001

[Community health policy as a research area in public health and social sciences].

The community plays a central role in new public health concepts. However, local health policy has not achieved a central role in cities and counties. Therefore it seems to be both reasonable and necessary for social sciences to analyse the health options in local politics and to identify aspects for improvement. The implementation of health priorities and their realisation at the local level, the latter with regard to supporting (positive) and hampering (negative) factors, and the development of strategies to implement health programmes are suggested as main research topics. Starting from the assumption that complex organisational processes in communities need organisational support, the role of the public health service as coordinating and initialising factor for the alteration of community health programmes should be investigated more thoroughly. The public health service as a part of the administration in municipalities is also involved in the endeavour to modernize administration. A main area for research will be how far the knowledge about participation of citizens and new management theories support health as a task of local politics.

Community Health Planning↗
PubMedDate not supplied

Promoting science-based prevention in communities.

In the past decade, prevention science has emerged as a discipline built on the integration of life course development research, community epidemiology, and preventive intervention trials [Am. Psychol. 48 (1993) 1013; Am. J. Community Psychol. 27 (1999) 463; Kellam, S. G., & Rebok, G. W. (1992). Building developmental and etiological theory through epidemiologically based preventive intervention trials. In J. McCord & R. E. Tremblay (Eds.), Preventing antisocial behavior: interventions from birth through adolescence (pp. 162-195). New York: Guilford Press.]. Prevention science is based on the premise that empirically verifiable precursors (risk and protective factors) predict the likelihood of undesired health outcomes including substance abuse and dependence. Prevention science postulates that negative health outcomes like alcohol abuse and dependence can be prevented by reducing or eliminating risk factors and enhancing protective factors in individuals and their environments during the course of development. A growing number of interventions have been found to be effective in preventing adolescent tobacco, alcohol, and other drug abuse, delinquency, violence, and related health risk behaviors by reducing risk and enhancing protection. During the same decade, comprehensive community-based interventions to prevent adolescent health and behavior problems have been widely implemented in the U.S. with federal and foundation support. Despite the advances in the science base for effective preventive interventions and the investments in community-wide preventive interventions, many communities continue to invest in prevention strategies with limited evidence of effectiveness [Am. J. Public Health 84 (1994) 1394; J. Res. Crime Delinq. 39 (2002) 3; J. Community Psychol. 28 (2000) 237; J. Community Psychol. 28 (2000) 237; J. Consult. Clin. Psychol. 67 (1999) 590; Eval. Program Plann. 20 (1997) 367.]. Translating prevention science into community prevention systems has emerged as a priority for prevention research [J. Community Psychol. 28 (2000) 363; J. Appl. Behav. Anal. 28 (1995) 479.]. The Communities That Care (CTC) prevention operating system is a field-tested strategy for activating communities to use prevention science to plan and implement community prevention systems. CTC provides tools that assist communities to use local data on risk and protective factors to identify elevated risks and depressed protective factors in geographic areas where levels of risk are high and levels of protection are low and then to implement tested, effective preventive interventions that reduce the identified risks and enhance protection in these [Developmental Research and Programs. (1997). Communities That Care: a comprehensive prevention program. Seattle, WA: Author; Developmental Research and Programs. (2000a). Communities That Care: a comprehensive prevention program. Seattle: Author; Hawkins, J. D., Catalano, R. F., et al. (1992). Communities That Care: action for drug abuse prevention (1st ed.). A joint publication of the Jossey-Bass social and behavioral science series and the Jossey-Bass education series. San Francisco: Jossey-Bass]. The CTC system is widely implemented, and process evaluations of CTC suggest that it can assist communities to develop more effective prevention systems. This paper describes the background and use of the CTC operating system and results of evaluations of implementation of the system.

Adolescent↗
PubMed2004

Connecting community action and science to combat desertification: evaluation of a process.

Combating desertification requires the involvement of many people ranging from communities who experience the effects on a daily basis and scientists attempting to understand the biophysical and socio-economic causes and consequences of desertification, to developers and policy makers on all levels. In many instances, however, the understanding, approaches and actions of these different groups contradict rather than support one another. Over the period 2000 to 2002, a conference process undertaken in southern Africa brought together communities, scientists, and development workers to test the concept that they could connect and work together to combat desertification, given an appropriate framework. The conference was a success, and communities, scientists and developers did exchange experience, knowledge and information. Many lessons were learned, although some pitfalls were experienced. Time, funding, enhanced communication, and good will are the primary ingredients for ensuring that different sectors complement one another in their efforts to combat desertification.

Community Participation↗