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PubMedDate not supplied

Injection drug use and HIV/AIDS transmission in China.

After nearly three decades of being virtually drug free, use of heroin and other illicit drugs has re-emerged in China as a major public health problem. One result is that drug abuse, particularly heroin injection, has come to play a predominant role in fueling China's AIDS epidemic. The first outbreak of HIV among China's IDUs was reported in the border area of Yunnan province between China and Myanmar where drug trafficking is heavy. Since then drug-related HIV has spread to all 31 provinces, autonomous regions and municipalities. This paper provides an overview to HIV/AIDS transmission through injection drug use in China. It begins with a brief history of the illicit drug trade in China, followed by a discussion of the emergence of drug related AIDS, and a profile of drug users and their sexual partners who have contracted the virus or who are vulnerable to infection. It ends by summarizing three national strategies being used by China to address both drug use and AIDS as major health threats.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

Care of HIV-infected patients in China.

Compared with high infection areas of the world, the total HIV infection rate in China is relatively low. Nonetheless, because of China's vast territory and large population, the potential infection risk must be taken seriously. In the next few years, needle sharing among injection drug users will remain the most common route of transmission for the HIV/AIDS epidemic in China. Unprotected sex is gradually becoming a major route of transmission. China began to implement HAART in 1999 according to international standards. Prior to 2003, there were only about 150 HIV/AIDS patients were treated with HAART in some clinical trials and about 100 HIV/AIDS patients were treated by private sources. Results of those treatments are the scientific basis for development of the therapeutic strategies in China. In March of 2003, the Chinese government initiated China CARES program. In November of 2003, the Chinese Ministry of Health announced a national policy of free ARV treatment to all HIV+ Chinese citizens who were in poverty and required ARV therapy. There are total of 19,456 HIV/AIDS patients received free ARV drugs to date in 159 regions and 441 towns. Current challenges are how to follow-up and evaluate those patients in the clinical settings. The longer the therapy is postponed, the more side effects and the higher probability of drug resistance are going to occur. It remains unclear, therefore, when HAART regimen should be started in the HIV/AIDS population in China.

Acquired Immunodeficiency Syndrome↗
PubMed1999

Case study of the effects of atmospheric aerosols and regional haze on agriculture: an opportunity to enhance crop yields in China through emission controls?

The effect of atmospheric aerosols and regional haze from air pollution on the yields of rice and winter wheat grown in China is assessed. The assessment is based on estimates of aerosol optical depths over China, the effect of these optical depths on the solar irradiance reaching the earth's surface, and the response of rice and winter wheat grown in Nanjing to the change in solar irradiance. Two sets of aerosol optical depths are presented: one based on a coupled, regional climate/air quality model simulation and the other inferred from solar radiation measurements made over a 12-year period at meteorological stations in China. The model-estimated optical depths are significantly smaller than those derived from observations, perhaps because of errors in one or both sets of optical depths or because the data from the meteorological stations has been affected by local pollution. Radiative transfer calculations using the smaller, model-estimated aerosol optical depths indicate that the so-called "direct effect" of regional haze results in an approximately 5-30% reduction in the solar irradiance reaching some of China's most productive agricultural regions. Crop-response model simulations suggest an approximately 1:1 relationship between a percentage increase (decrease) in total surface solar irradiance and a percentage increase (decrease) in the yields of rice and wheat. Collectively, these calculations suggest that regional haze in China is currently depressing optimal yields of approximately 70% of the crops grown in China by at least 5-30%. Reducing the severity of regional haze in China through air pollution control could potentially result in a significant increase in crop yields and help the nation meet its growing food demands in the coming decades.

Agriculture↗
PubMed2001

Remedial strategies for municipal solid waste management in China.

The purpose of this investigation is to evaluate the current status and to identify the problems of municipal solid waste (MSW) management in China to determine appropriate remedial strategies. This is the second of two papers proposed on this topic. Major problems or difficulties identified in MSW management in China include MSW land, air, and water pollution, commingled collection, poor administration, shortage of funds, lack of facilities, and problems of training and public awareness. In order to solve these problems and to improve MSW management in China, remedial strategies in three areas are recommended: institutional reform, technology development, and legislation and administrative improvement. The primary principle involved in institutional reform is unifying legislative responsibilities into one body and developing a market mechanism for handling MSW. Composting, landfills, and incineration should be equally developed in accordance with China's needs. The feasibility of developing technology to handle MSW in China is discussed. Also recommended is the establishment of sound regulatory systems, including a service fee system, a source separation system, and a training program. China is presently undergoing economic and institutional reform at the national and local levels. Results of this study will provide useful information on MSW management in China.

China↗
PubMed1992

Medical education and medical education research and development activities in modern China.

The development of medical education in China occurred quite differently to medical education in the rest of the world. A review of the literature has been presented regarding the historical development and the evolution of medical education research and development (MERAD) units in modern China. The history of medical education in modern China has been divided into three periods: (1) the 17 years before the 'Cultural Revolution' (1949-1966); (2) the period of the 'Cultural Revolution' (1966-1976); (3) the post 'Cultural Revolution' period (1976 onwards). Although a number of MERAD activities had existed on China's medical campuses since 1949, there was no formal organizational structure for MERAD before 1978. The change of the political situation in 1978 led China to seek modernization, with education as its basis. In the process of health care system modernization, medical education was given priority, and the Western model of establishing MERAD units as a means of improving the training of health professionals was introduced. The evolution of medical education research and development in modern China appears to be following the Western pattern due to the multitude of Western consultants and fellowships in Western countries provided to Chinese medical education leaders. A group of people from medicine is gathering in the MERAD field and MERAD units are beginning to take shape in modern China.

China↗
PubMed1994

Helicobacter pylori epidemiology in relation to peptic ulcer and gastric cancer in south and north China.

Peptic ulcer disease is twice as common in people living in South China when compared with those in North China. However, the gastric cancer rate in North China is three times that of South China. The overall Helicobacter pylori prevalence rate is similar in North and South China populations and it is higher than Caucasians living in Western societies. However, there is a significantly higher prevalence of H. pylori seropositivity among those who live in the high gastric cancer areas of China. On the other hand, there is no significant difference in the H. pylori positive rate in the peptic ulcer disease patients between the two regions of China. Other permissive/associated co-factors in the development of peptic ulcer disease or gastric cancer remain unknown at this stage.

China↗
PubMedDate not supplied

Nursing in the People's Republic of China.

In June, 1994 Dr. Grayce Roessler led a group of nurses to China to attend and present at international nursing conferences in Beijing and Shanghai. Dr. Roessler, an internationally known transcultural nursing leader, has traveled extensively in China (some 36 trips over 20 years). Her first trip to China, focused on nursing, took place in the fall of 1981 as a member of the American Nurses Association (ANA). The ANA group was invited to China by the Chinese government and the Chinese Nurses Association (CNA). Subsequent to that visit, she became involved in working with the Chinese Ministry of Health, the Chinese Nurses Association, and several of the CNAs in various cities throughout China. In an effort to assist in the preparation of Chinese nurses as teachers and administrators in the evolving health care system, Dr. Roessler facilitated a one year (1985-86) study program in the United States (Golden West College, Huntington Beach, California) for a group of 20 Chinese nurses. It was the first time in history that a number of Chinese nurses had studied at one institution with American nurses in the United States. Dr. Roessler has since coordinated several international conferences in China and arranged for American nurse experts in various fields to present at these meetings. In addition, she has traveled independently as a teacher and consultant and has taken numerous nursing study tour groups to many countries as part of continuing educational experiences. In this issue of the Journal of Transcultural Nursing, Dr. Roessler presents her reflections on nursing in China from a historical and transcultural nursing leader's perspective.

China↗
PubMed1998

Health effects of indoor fluoride pollution from coal burning in China.

The combustion of high fluoride-content coal as an energy resource for heating, cooking, and food drying is a major exhaust emission source of suspended particulate matter and fluoride. High concentrations of these pollutants have been observed in indoor air of coal-burning families in some rural areas in China. Because airborne fluoride has serious toxicological properties, fluoride pollution in indoor air and the prevalence of fluorosis have been analyzed in a fluorosis area and a healthy nonfluorosis area in China and in a rural area in Japan. For human health, fluoride in indoor air has not only been directly inhaled by residents but also has been absorbed in stored food such as corn, chilies, and potatoes. In the fluorosis area in China, concentrations of urinary fluoride in the residents have been much higher than in the nonfluorosis area in China and in the rural area in Japan. In the fluorosis area, almost all elementary and junior high school students 10-15 years of age had dental fluorosis. Osteosclerosis in the skeletal fluorosis patients was very serious. Urinary deoxypyridinoline in rural residents in China was much higher than in rural residents in Japan. Data suggest that bone resorption was extremely stimulated in the residents in China and that fluoride may stimulate both bone resorption and bone formation. Because indoor fluoride from combustion of coal is easily absorbed in stored food and because food consumption is a main source of fluoride exposure, it is necessary to reduce airborne fluoride and food contamination to prevent serious fluorosis in China.

Adolescent↗
PubMed2006

An overview of veterinary medical education in China: current status, deficiencies, and strategy for improvement.

Especially in developing countries, the profession of veterinary medicine is closely tied with agriculture and government economic development, the national structure of education, and national public health. Currently, the Chinese veterinary medical educational system and accreditation standards are distinctly different from those of some more developed countries, such as the United States, Japan, or the countries of the European Union. Chinese veterinary education is still closely based on traditional Chinese education approaches and standards, which has led to some deficiencies in the Chinese system. With the development of a stronger economy in China and the growing trend toward globalization, and particularly since China joined the World Trade Organization (WTO), some important questions about China's system of veterinary education are being raised: How can veterinary science develop more rapidly in China? How can it meet the needs of the growing Chinese society? How can China bring its veterinary medical practice more in line with that of other, more advanced countries? This article describes some of the realities of veterinary medical education in China, discusses several existing problems, and puts forward some ideas for possible reforms. It is hoped that by this means those outside China may gain insight into our veterinary education program and that this, in turn, will lead to helpful input from international educators and other professionals to help improve our programs.

China↗
PubMed2000

A nine-year prospective study on the incidence of childhood type 1 diabetes mellitus in China.

To investigate the epidemiological characteristics of childhood type 1 diabetes mellitus in China, newly diagnosed cases of type 1 diabetes with an onset age under 15 years were retrospectively registered by 23 local centers in China following a standardized protocol on the basis of the nationwide registry established by the WHO DiaMond Project China Participating Center, Chinese Academy of Preventive Medicine (CAPM). A population of about 24 million children were covered in the defined areas. A two-sample capture-recapture method was used to estimate case ascertainment. Between 1988 and 1996, 903 diabetic cases were registered in 9 ethnic groups. The overall ascertainment corrected incidence rate (IR) was 0.59 per 100,000 person-year. The IR was 0.52/100,000 (95% CI: 0.50-0.54) for males and 0.66/100,000 (95% CI: 0.64-0.68) for females. The standardized ascertainment corrected IR by the national age-specific population in 1990 was 0.57 per 100,000 person-year. The incidence among various ethnic groups ranged from 0.25/100,000 to 3. 06/100,000. The IRs increased with northern latitude, and the IR of Han population was significantly higher in North China compared with South China (0.67 versus 0.53 per 100,000 respectively, P < 0.01). A correlation model of incidence and calendar time showed that the IR increased significantly between 1988 and 1996 (r = 0.86, P = 0.0027). The relative risk (RR) of type 1 diabetes mellitus for different age-groups estimated by a Poisson regression model showed that taking RR as 1.00 for age-group from 0 to 4 years, the RR for age-group from 5 to 9 year and from 10 to 14 year was 2.30 and 3.60 respectively. The standardized ascertainment corrected IR of childhood type 1 diabetes mellitus in China in much lower than in other countries. The geographic and ethnic variability of the incidence suggests that both genetic and environmental factors play a role in the development of childhood diabetes in China.

Adolescent↗
PubMed2001

[HLA-DRB1 gene polymorphism of Naxi ethnic group of Yunnan Province, China and its ethnological evolution analysis].

The HLA-DRB1 gene polymorphism of Naxi ethnic group of Yunnan Province, China was investigated for the first time using high resolution PCR-SBT method, which is based on sequences of HLA-DRB1 Intron 1 and Intron 2 with our improvement. From 60 individuals of Naxi 37 DRB1 alleles were detected. The distribution of allele frequencies is evenly spread for most of alleles detected in Naxi. However, the gene frequency for HLA-DRB1 * 12021 is 17.50%. The other common alleles (> 5%) were HLA-DRB1 * 1404(7.50%), 1504(5.83%), 04051(5.83%), 08032(5.83%), 09012(5%), 03011(5%), and they covered 35% of the total alleles detected from Naxi, and 52.49% after adding the frequency of HLA-DRB1 * 12021. HLA-DRB1 * 0305, 0438, 1123, 1132, 1310, 0812 were detected in Chinese for the first time, and were very rare in other ethnic groups worldwide. Using the HLA-DRB1 gene frequencies of various ethnic groups, we constructed the phylogenetic tree by Fitch-Margoliash and Least-Squares Distance Methods and Cavalli-Sforza's chord measure of genetic distance. In our dendrogram, the South China populations were clustered together, and Siberian, Japanese and Minority of North China were clustered together, in which two big clusters we thought represented the ancient Southern and Northern Mongolian. Our results showed Naxi was clustered with Lahu and Yao ethnic groups, which were in the cluster of South China population. Obviously Naxi belongs to the South China ethnic groups and can't trace its origin from northern ethnic groups with the HLA-DRB1 genetic data. But based on Naxi's historical folklore, it was down to Southern China from Northwest China. The preliminary analysis about its origin conundrum was discussed in this paper based on our genetic data in relationship with its history and ethnology studies.

China↗
PubMed2002

[Vegetation uptake of nitrogen and base cation in China and its role in soil acidification].

Vegetation uptake of nitrogen and base cation, as well as acid deposition, is an important source of soil acidity. Based on the net primary productivity and elemental composition, the uptake rate of nitrogen and base cation was estimated for each vegetation type in China. Result showed that the uptake rate of nitrogen was commonly low in southeast China and high in northwest China, and decreased gradually from southeast to northwest in northwest China. In addition, the uptake rate of base cation was very high (> 2.0 keq.(hm2.a)-1) for subtropical/tropical broadleaf evergreen forest, temperate limestone broadleaf deciduous forest, temperate deciduous shrub, and subtropical/tropical savanna in the northeast of Huabei Plain, the south of Yunan province, and the west of Hainan Island respectively, and low (< 0.5 keq.(hm2.a)-1) for subtropical evergreen coniferous forest in east China and deserts and steppes in arid region of west China. Although vegetation uptake caused no increase of soil acidity in almost all areas in China, the acidity input caused by vegetation uptake was quite high (> 0.5 keq.(hm2.a)-1) and even higher than the current acid deposition in some areas, where soil acidification might happen because the total acidity input exceeded the alkalinity produced by soil weathering.

Acids↗
PubMed2003

[An analysis about genetic basis of cotton cultivars in China since 1949 with molecular markers].

The diversity of 166 cotton cultivars(cult.) including 159 upland(G. hirsutum L) and 7 island(G. barbadense L) ones planted mainly in China since 1949 was explored by RAPD, genetic distance(GD) and cluster analysis. The correlation coefficients between Nei's GD of RAPDs and two groups of phenotype data's Euclidean distances (UD) were 0.6445(n = 1770) and 0.7078 (n = 7140), which indicated that RAPD could be used to explore genetic diversity among cotton cultivars in China. The genetic basis of cotton cultivars in China was studied by comparison among different cotton species, different cultivar types, different history periods, different growing regions and different sources. The results showed as follows:within cotton cultivars planted in China, the genetic basis of island cotton cultivars was narrower than that in upland ones; the genetic basis of cultivars released in China since 1949 was narrower than that of introduced ones from outside of China; the genetic basis of hybrids was narrower than that of conventional cultivars(Conv. Cult.); the genetic basis of upland cultivars after 1980 was narrower than that in 1970's; the genetic basis of cultivars in Changjiang cotton region was narrower than that of Huanghuai cotton region, northwestward cotton region was the narrowest. From which some strategies for breeding, especially for the methods of widening the genetic basis of China cotton cultivars, could be understood and withdrawn.

China↗
PubMed2003

[Changes of mortality rate for cervical cancer during 1970's and 1990's periods in China].

OBJECTIVE: To describe the distribution changes of the mortality rate for cervical cancer in China between the 1970's and 1990's and provide the scientific evidence for the prevention and control strategies for cervical cancer campaign in China between next century. METHODS: Data from two National Surveys for the Causes of Death in 1970's and 1990's in China. The crude and adjusted mortality rates for the cervical cancer and the distributions based on age and area were calculated and described. The comparison of the differences of changes between two mortality rates periods and together with its trends were shown based on the age-standardized. RESULTS: During two decades, the mortality rate for cervical cancer was 10.7 per 100,000 in 1970's which declined to 3.89 per 100,000 in 1990's, and from the 3rd ranking among all female malignant tumors to the 6th in 1990's (decreased about 63.64%). But the declination was not evenly. There have still been some high-risk areas, most located in rural countries in the mid-west of China, with rates remain unchanged and even at the highest level in the world, such as Wudu in Gansu and Yangcheng in Shanxi. A big difference was showed between rural country and city, but in both of them, the mortality rates in 1990's were significantly much lower than in 1970's (P = 0.001) at each five-year age group. And in the city, there was a much sharper increased trend in young women in 1990's. CONCLUSIONS: The mortality rate for cervical cancer campaign in China has been substantially declined during past twenty years, but it's still a major health problem for women, especially in rural China. The focus of the prevention and control for the cervical cancer in the next century should put on rural areas, especially in mid-west of China and young women in the city.

Adult↗
PubMed2003

[What the Prorocentrum species should be?--a review on identification of a Prorocentrum species from the East China Sea].

In the past decade, the Prorocentrum bloom was the most frequently occurred bloom in the East China Sea. It occurred every one year or two years, and covered huge areas. There were arguments on the identification of Prorocentrum bloom causative species. Some scientists thought the species being P. dentatum Stein, but the others thought that it was a new species, P. donghaiense Lu. For achieving the proper classification of the species, an "International Workshop on HAB Causative Species--Taxonomic View on a species of Prorocentrum in the East China Sea" was held in Shenzhen, China in November, 2002. By reviewing as much as available references, and by comparing the Prorocentrum specimen from the East China Sea with those from Japan, Korea and USA, scientists participated in this Workshop agreed that: 1) the specimens from Japanese and Korean waters, and from CCMP, USA were the same species; 2) the features of anterior projection and cell surface marking were similar to those of originally described P. dentatum Stein; 3) the major difference is the cell size. The specimens from the East China Sea were mostly less than 20 microns long, whereas the size of the original described P. deatatum was larger than 50 microns; 4) the minor difference is the shape of the cell end. The original described P. deatatum was with a pointed end, whereas the cells from the East China Sea were mostly with a rounded end. There was no final agreement for the species identification at the Workshop. By summing all views of scientists from the Workshop, the authors suggested that the bloom causative species of Prorocentrum in the East China Sea, as well as so-called species of P. dentatum from other East Asian waters, should be the same species. They are all P. donghaiense Lu.

China↗
PubMed2003

Epidemiology of alveolar echinococcosis with particular reference to China and Europe.

Human alveolar echinococcosis (AE), caused by the metacestode of the fox tapeworm Echinococcus multilocularis, is the most pathogenic zoonosis in temperate and arctic regions of the northern hemisphere. Prospective collection of human cases in some areas and mass screenings using ultrasound imaging and confirmation with serological techniques have markedly improved our knowledge of the epidemiology of the disease in humans during the past two decades. Transmission occurs when eggs of the tapeworm, excreted by the final hosts (usually foxes but also dogs, wolves and cats), are ingested accidentally by humans or during normal feeding by a variety of rodents and small lagomorphs. However, the species of host animals differ according to regional changes in mammalian fauna. This review mostly focuses on epidemiology of alveolar echinococcosis in those parts of the world where new and more accurate epidemiological data are now available, i.e. China and Europe, as well as on new epidemiological trends that can be suspected from recent case reports and/or from recent changes in animal epidemiology of E. multilocularis infection. The People's Republic of China (PRC) is a newly recognized focus on AE in Asia. Human AE cases were firstly recognized in Xinjiang Uygur Autonomous Region and Qinghai Provinces at the end of 1950s and infected animals were first reported from Ningxia in central China and northeast of Inner Mongolia in the 1980s. E. multilocularis (and human cases of AE) appears to occur in three areas: (1) Northeastern China (northeast focus): including Inner Mongolia Autonomous region and Heliongjiang Province (2) Central China (central focus): including Gansu Province, Ningxia Hui Autonomous Region, Sichuan Province, Qinghai Province and Tibet Autonomous Region and (3) Northwestern China: including Xinjiang Uygur Autonomous Region, bordered with Mongolia, Russia, Kazakhstan and Kyrgyzstan. The highest prevalence of the disease, up to 15 per cent of the population in some villages, is reached in China. In Europe, data from the European Echinococcosis Registry (EurEchinoReg: 1982-2000) show 53 autochthonous cases of AE in Austria, 3 in Belgium, 235 in France, 126 in Germany, 1 in Greece, and 112 in Switzerland, and 15 'imported' cases, especially from central Asia; 14 cases were collected in Poland, a country not previously considered endemic for AE. Improved diagnostic technology, as well as a real increase in the infection rate and an extension to new areas, can explain that more than 500 cases have been reported for these 2 decades while less than 900 cases were published for the previous 7 decades. New epidemiological trends are related to an unprecedented increase in the fox population in Europe, to the unexpected development of urban foxes in Japan and in Europe, and to changes in the environmental situation in many countries worldwide due to climatic or anthropic factors which might influence the host-predator relationship in the animal reservoir and/or the behavioural characteristics of the populations in the endemic areas.

Adolescent↗
PubMed2005

Combating HIV/AIDS in Mainland China: an epidemiological review of prevention and control measures.

Two decades have already passed since the first HIV/AIDS case was described in 1981. Cumulatively, over 20 million people have unfortunately lost their lives, and more than 40 million people are now living with HIV, and most of them are from developing countries. China, as the biggest developing country, has an impact on the epidemic of HIV/AIDS. From the first case of AIDS diagnosed in Mainland China in 1985, the epidemic has spread at an alarming rate. The feature of HIV/AIDS spread in Mainland China concerns its geographical characteristics that can be described as occurring in three phases. According to data from World Health Organization (WHO), it was estimated that about 840,000 people are living with HIV/AIDS in China, and 80,000 of them have already developed AIDS. WHO warned that, if there were no effective preventive measures adopted, that the number of HIV/AIDS infected cases would reach 10 million in China by 2010. In this study, we described the current situation of the epidemic of HIV/AIDS, as well as an historic review. The development of policy-making and the control measures are also highlighted. The experience from China described in this study would hopefully be for more public awareness of this crisis that is threatening all the citizenry of China.

Acquired Immunodeficiency Syndrome↗
PubMed2006

[Surveillance on contamination of total aflatoxins in corn, peanut, rice, walnut and pine nut in several areas in China].

OBJECTIVE: To realize the contamination of total aflatoxins in corn, peanut, rice, walnut and pine nut in China, and provide the base data for establishing a China tolerance limit standard and an international control practice for total aflatoxins. METHODS: The samples of corn, peanut, rice, walnut and pine nut from Chongqing, Fujian, Guangdong, Guangxi, Hubei, Jiangsu, Shanghai and Zhejiang provinces and municipalities were collected randomly from markets, with the totally 284 samples. The samples were grounded and added to acetonitrile/water mixture. After filtering, the extract was transferred into a purifying column and pressed slowly. Then the purified liquid was derivatized with trifluoroacetic acid (TFA) and detected by using a high performance liquid chromatography (HPLC). RESULTS: There was 70.27% corn having been detected out an average level of aflatoxins of 36.51 microg/kg and the highest level was 1098.36 microg/kg. At the same time, there was 14.86% corn exceeding the China national tolerance limit. In peanut, the aflatoxins detected rate was 24.24%. The average level was 80.27 microg/kg and the highest level was 437.09 microg/kg. While there was 3.03% peanut exceeding the China national and Codex tolerance limits. All of the rice, walnut and pine nut samples met the China tolerance limit for aflatoxins. CONCLUSION: Corn and peanut might be the severely contaminated foods with aflatoxins in China. The aflatoxin B(1) in foods might be can not delegate the contamination of aflatoxins completely. Surveillance of total aflatoxins in foods suggested an actual need of establishing the China national and international standards for total aflatoxins.

Aflatoxins↗