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At least 163 records · Page 9Linked to original sources

Metastatic basal cell carcinoma of the axilla: report of a case and reconstruction with an island lateral pectoral flap.

A case of metastatic basal cell carcinoma arising from the skin of the axilla is reported. Multiple surgical procedures performed previously for recurrences of basal cell carcinoma limited the availability of conventional local flaps in the reconstruction of the axillary defect after excision of the recurrent tumor and axillary nodal dissection. The use of an island flap based on the lateral pectoral vessels and lateral cutaneous branches of the intercostal vessels is described.

Axilla↗

Ten years of experience in managing patients with burn contractures of axilla, elbow, wrist, and knee joints.

An analysis of 625 patients who had sustained burns across the axillae, elbows, wrists, or knee joints indicates that the use of splints and pressure across these joints will not only greatly decrease the incidence of contractures but will also reduce the frequency and need for release operations. However, these appliances must be used for at least 6 months (longer, if possible), if substantial benefits are to be obtained.

Axilla↗

Verrucous carcinoma of the axilla: case report and review.

BACKGROUND: Verrucous carcinoma, a variant of squamous cell carcinoma, is distinct from squamous cell carcinoma in morphology and behavior. It preferentially occurs on the oropharyngeal mucosa, the urogenital mucosa, and the soles. In contrast to its malignant clinical picture, the tumor grows locally invasive but is histologically benign and metastasizes rarely. METHODS: We report the uncommon occurrence of a large verrucous carcinoma on apparently uninvolved skin in the right axilla in a 47-year-old male. RESULTS: Histologic examination reveals a cauliflower-like tumor consisting of deep invaginated epidermal proliferation with rabbit burrow-like, keratin-filled sinus formations; the basement membrane, however, remains intact. Immunohistology showed positivity for pancytokeratin (KL-1) and cytokeratin (CK) 18 and negativity for CK7, and assessment of the proliferative activity of the tumor cells revealed low percentage of Ki-67 expression. Furthermore, there were only scattered cells expressing p53 or bcl-2. Polymerase chain reaction excluded the presence of human papillomavirus. After complete excision, no signs of recurrence occurred over a follow-up period of three years. CONCLUSION: Verrucous carcinoma should be distinguished from typical squamous cell carcinoma. The clinicopathological features, differential diagnosis, and therapy are discussed here together with the molecular biologic aspects of the tumor.

Axilla↗

Mondor's disease of the axilla: a rare complication of sentinel node biopsy.

Three cases of Mondor's disease of the axilla following sentinel lymph node biopsy (SLNB) are described. In all cases we used the combination of blue dye and radiocolloid, and complete axillary dissection was not performed. The numbers of lymph nodes removed in each case were five, four, and two, respectively. All the events of Mondor's disease resolved spontaneously or following a short therapy of anti-inflammatory agents.

Anti-Inflammatory Agents↗

Diffuse neonatal hemangiomatosis with a giant cutaneous hemangioma on the axilla.

A case of diffuse neonatal hemangiomatosis is described. At birth, a giant tumor, 10 cm in diameter and 6 cm in height, was present on the left axilla and associated with thrombocytopenia. Numerous cherry-red papules were present on the skin and buccal mucosa. On the second day of life, the giant tumor was excised. Histological examination of the tissue revealed masses of endothelial cells embedded in fibrous tissues. Plain and enhanced computed tomography of the brain revealed a hemorrhage and two hemangiomas. The associations of intravascular papillary endothelial hyperplasia were discussed.

Axilla↗

Clinical observations on the development and eventual character of hair in the axillae of human beings.

The authors examined clinically growth and patterns of axillary hair of Japanese males and females of various ages with a specific interest in the differences between vellus and coarse hairs. One notable finding was that in the axillae of children, vellus hairs are equidistant and solitary, whereas the coarse hairs that replace them emerge during puberty as solitary hairs and in bundles or groups. A statistical summary and speculation as to why growth of vellus hair and growth of coarse hair differ are the substance of this report.

Adolescent↗

Genital Paget's disease with clear cells in the epidermis of the axilla.

We report an 84-year-old man with extramammary Paget's disease (EMPD) involving the genital region. Microscopic examination revealed very few clear cells appearing pagetoid in the lower portion of prickle cell layer of the right axilla epidermis, with no clinically detectable eruption. Their histochemical, immunohistochemical and lectin-binding reactions were almost identical to those in the genital lesion. However, although the axillary lesion was diagnosed as subclinical Paget's condition, the clinical course showed no aggressive or destructive nature. Our case suggests that not all subclinical Paget's conditions become malignant, and that in some cases the clear cells may be precursors of Paget's cells developing multifocally.

Aged↗

Gender difference of in vivo skin surface pH in the axilla and the effect of a standardized washing procedure with tap water.

The purpose of our study was to evaluate the axillary skin surface pH and explore potential gender-related differences together with the influence of a washing procedure in healthy subjects. After a run-in period, the skin surface pH was measured in vivo in 10 men and 10 women under standardized conditions in three distinct locations of each axilla (at baseline and up to 6 h after washing). Potential interfering influences were thoroughly excluded. Our study revealed a statistically significant difference in axillary skin surface pH between men and women with more acidic values in females (p < or = 0.001). The baseline axillary pH before washing was 6.58 +/- 0.63 (right) and 6.67 +/- 0.65 (left) in men compared to 5.8 +/- 0.53 (right) and 5.94 +/- 0.62 (left) in women. The difference between the right and left arm-pit was not statistically significant (p > 0.05) in any group. After standardized washing procedures with pure tap water, the mean axillary pH decreased significantly in women at all measurement times [lowest value 60 min after washing: 5.51 +/- 0.7 (right) and 5.64 +/- 0.7 (left)], while it slightly increased in men [highest value 240 min after washing: 6.7 +/- 0.59 (right) and 6.78 +/- 0.69 (left)]. In summary, there is a gender difference in axillary skin surface pH. Washing with water further increased the difference between male and female pH values.

Adult↗

Giant chondroid syringoma of the axilla.

BACKGROUND: Chondroid syringomas are benign uncommon tumours of controversial histogenesis that most often affect the head and neck region and usually measure > 3 cm in greatest dimension. OBJECTIVE: To describe the clinical features, histology, and differential diagnosis of an unsually large axillary chondroid syringoma. METHODS: A 64-year-old man presented with a painless, subcutaneous tumour measuring 8 3 7 3 6.5 cm on his right axilla, which had been growing slowly for several years. The tumour was completely excised under local anesthesia. No recurrence of the tumour has been observed 12 months after surgery. RESULTS: Histological examination showed cords, nests, and tubuloglandular structures composed of well-differentiated tumour cells embedded in a hyalinized stroma with abundant chondroid matrix, and the diagnosis of chondroid syringoma was established. No features suggesting malignancy were observed. CONCLUSION: As this case shows, chondroid syringoma may reach a large size, and it should be included in the differential diagnosis of slowly growing solid nodules in the skin or subcutis.

Adenoma, Pleomorphic↗

Pilomatrix carcinoma of the axilla: CT and MRI features.

Pilomatrix carcinoma, a rare malignant soft tissue tumour, is the malignant variant of pilomatricoma. We report a case of pilomatrix carcinoma of the axilla. CT demonstrated a well-circumscribed, sand-like calcified mass. MRI showed diffusely inhomogeneous, mixed signal intensities with inhomogeneous enhancements. The MRI findings were different from those previously reported for pilomatricoma.

Axilla↗

Reconstruction in the axilla with a pedicled pectoralis minor muscle flap.

Covering large defects in the axillary fossa can be challenging because of its complex shape. A variety of local skin, fasciocutaneous and musculocutaneous flaps have been described, with a number of inherent advantages and disadvantages. The use of the pectoralis minor muscle as a pedicled transposition flap has been described for immediate reconstruction of the breast, anterior shoulder reconstruction and the treatment of bronchopleural fistula. We now describe the use of a pedicled pectoralis minor muscle flap for soft tissue coverage of the axillary contents after wide excision of the axilla. This has not been previously described.

Axilla↗

Reciprocal changes in nasal resistance to airflow caused by pressure applied to the axilla.

The resistance to airflow of each nasal passage was measured using active, posterior, rhinomanometry. Application of pressure to the axilla for 15 min by means of a wooden crutch caused a reciprocal change in nasal resistance with an ipsilateral increase and a contralateral decrease in resistance. The results are discussed in terms of reflex changes in sympathetic tone to the nasal venous erectile tissue.

Adolescent↗

The effect of pressure and warmth applied to the axilla on unilateral nasal airway resistance and facial skin temperature.

The effect of pressure, warmth, and control stimuli applied to the axilla and lateral chest wall on unilateral nasal airway resistance and facial skin temperature was investigated in 60 healthy adults. Nasal resistance was measured by posterior rhinomanometry and skin temperature with an infrared thermometer. A significant increase in unilateral nasal resistance ipsilateral to the applied stimulus was seen with both pressure and warmth (p = 0.006, p = 0.02). A decrease in unilateral nasal resistance contralateral to the stimulus was seen in both these groups, but this was not significant (p = 0.45, p = 0.81). The control stimulus showed a non-significant increase in unilateral nasal resistance ipsilateral to the applied stimulus (p = 0.55), and a significant rise in unilateral nasal resistance on the contralateral side (p = 0.008). There were no significant differences between the ipsilateral and contralateral facial skin temperatures before or after the application of a unilateral pressure, warm or control stimulus. A significant bilateral increase in facial temperature was observed during the course of the experiment in all three groups. The mechanisms of induced changes in unilateral nasal resistance are discussed. The results increase our knowledge of the corporo-nasal reflex and demonstrate that the reciprocal changes in sympathetic tone to the nasal capacitance blood vessels are independent from any parallel reflex changes in sympathetic tone to cutaneous blood vessels.

Adolescent↗

Myofibroblastoma of the axilla.

A mass in the axilla of a 47-year-old woman was biopsied and resected. The mass was composed of a loosely distributed population of spindle cells that were immunoreactive for smooth-muscle actin. Ultrastructurally, the cells possessed abundant endoplasmic reticulum, and some contained peripheral smooth muscle myofilaments, establishing that they were myofibroblasts. Mitotic activity was sparse, there was no cytologic atypia, and by flow cytometry the tumor was diploid with a low S phase. A diagnosis of myofibroblastoma was favored, although the possibility of a low-grade sarcoma could not be excluded. There has not been any indication of recurrence over a 4-month period of follow-up.

Axilla↗

Abrasio axillae in hyperhidrosis.

Forty-one patients with hyperhidrosis axillae were operated on. The subcutaneous curettage in 20 patients was compared with radical excision in 21 patients. Comparison of the results of both operations disclosed no difference in the elimination of the sweat secretion, but the method of curretage is superior, because it can be repeated if necessary and leaves practically no scars.

Axilla↗

Surgical treatment of hyperhidrosis axillae.

58 patients have been operated on for axillary hyperhidrosis by excision of the skin and subcutaneous tissue. The hyperhidrotic area was determined by application of a crêpe paper in the axilla. Either 60% or 90% of the hyperhidrotic area was excised, using a bat-like pattern. Only after excision of 90% of the hyperhidrotic area acceptable results were achieved. In a series of 22 patients with 90% excision bilaterally 18 had excellent results, three were good, and one was poor. The entire series was without complication. The advantage of this technique is its simplicity, freedom from complication, performance on an out-patient basis, and short convalescent time.

Adolescent↗