Alchemy--lessons from the history.
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Sccoiridoid biophenols, contained in olive drupes, are enzymatically activated to provide a complex mechanism for the biological defence against pathogen attack. Their identification, quantitation and metabolic behaviour are investigated, by HPLC and NMR experiments, for the improvement of olivegrowing and of the production of oil and table olives.
In rodents, bone marrow contains stem cells that have the potentiality to differentiate into mesodermal and non-mesodermal cells, both in vitro and in vivo. These cells can populate a wide panel of organs such as the liver, the brain, the lungs, the heart.... They appropriately differentiate according to the environment in which they migrate and are known to assume specific functions. Even in adult animals, these cells can migrate and differentiate. Such a potentiality suggests exciting therapeutic outcomes. Brain lesions could benefit of such techniques. These experimental protocols should be precisely controlled before their use in medicine in order to solve problems that still remain such as the permeability of the hemato-encephalic barrier, the integration of differentiated grafted cells into local functional neural networks.
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