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[Variation of the leukocyte number and formula in pregnancy in relation to the ABO blood group and Rh (D) factor].

A statistical research has been carried on 334 pregnant women considering the variation of leucocyte number and leucocyte formula beginning from the 2nd month on. The resulting variations either of the leucocyte number or their formula structure might favour etiological researches for a better understanding of the deep changes caused by pregnancy. These variations refer also to blood group (ABO) and Rh (D) factor.

ABO Blood-Group System↗

Factor-analytic study of the Anorectic Behavior Observation Scale in Japan: comparisons with the original Belgian study.

The Anorectic Behavior Observation Scale (ABOS) is a questionnaire developed to obtain information from relatives about behaviors and attitudes of patients with eating disorders. The original report of the ABOS revealed three factors. This is the first study to confirm the factor structure by use of confirmatory analyses. Relatives of 102 patients with eating disorders completed the ABOS, and exploratory factor analyses were performed. Confirmatory factor analyses were performed for this Japanese sample, and the fitness of the factor structure was compared between that in the original report proposed by Vandereycken and that used in the present study. A three-factor structure was revealed by the data of Japanese patients, including factor I (eating behavior meeting the criteria of anorexia; concern with weight, foods, and denial), factor II (bulimia; including bingeing, disposing, furtive eating and purging, and talk about thinness and dieting), and factor III (hyperactivity, eating slowly, and chopping food into very small pieces). Confirmatory analyses supported the improvement of fitness in this modified three-factor structure in comparison with the original three-factor model. This Japanese ABOS study revealed three dimensions, which differed from the original subscales in Belgium. Cross-cultural differences were observed, though the ABOS may be useful in Japan as an instrument for assessing eating disorders.

Adolescent↗

A linkage study of manic-depressive disorder with HLA antigens, blood groups, serum proteins and red cell enzymes.

Families with a two-generational history of affective disorder and well and ill sibs were selected from a population of bipolar manic-depressive patients and typed for HLA antigens, blood groups, serum proteins and red cell enzymes. Segregation of specific HLA alleles was not associated with affective illness across family pedigrees. Further, no significant associations were found between affective disorder and ABO, Rh, MNSs blood groups or Hp, EsD, C3, Gc or PGM. Using the lod score method of Morton (1955) for determining linkage, these data indicated that close linkage is unlikely for affective disorder and HLA alleles, haptoglobin, Rh factor, or ABO blood groups.

Adolescent↗

Epidemiology of gonorrhea among men in the Israel Defense Forces.

During a 4-year period, gonorrhea was diagnosed in 1,119 male members of the Israel Defense Forces who were 18 to 21 years of age. Asian and North African ethnic origin, fewer years of schooling, and low socioeconomic status were found to be important risk factors. The ABO blood groups were not found to be associated with the occurrence of disease.

Adolescent↗

ABO blood group determines plasma von Willebrand factor levels: a biologic function after all?

For many years, an association between ABO histo-blood group and risk of thrombosis has been recognized. Blood group non-O (A, B, and AB) individuals have consistently been found to demonstrate increased incidence of both arterial and venous thrombotic disease, compared to group O individuals. This increased risk is attributable to the fact that ABO blood group influences plasma levels of a coagulation glycoprotein named von Willebrand factor (VWF). VWF levels are 25 percent higher in non-O compared to group O individuals. The mechanism by which ABO group determines plasma VWF levels has not been determined. ABO(H) carbohydrate antigenic determinants, however, are expressed on the N-linked glycan chains of circulating plasma VWF. This review will focus on the carbohydrate structures of VWF and recent studies suggesting that subtle variations in these structures (particularly differences in ABO blood group antigen expression) may have clinically significant effects on VWF proteolysis and clearance.

ABO Blood-Group System↗

[ABO and Rh blood group factors in thyroid gland diseases].

The blood groups of 1012 patients were investigated that underwent operations in connection with the following thyroid diseases: Basedow's disease, basedowified goiter, toxic adenoma with thyroid carcinoma. Significant discrepancies were established not to exist as compared with the distribution of the blood groups among the Bulgarian population. The percentage of the patients with blood group A is only higher in carcinoma of the thyroid gland -- 50.2 per cent and in blood group O -- lower 27.8 per cent. The comparison with a control group of 307 patients with gastric carcinoma revealed that the percentage of blood group A is considerably higher -- 54.1 per cent among them.

ABO Blood-Group System↗