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[Treatment of rhegmatogenous retinal detachment complicated by vitreous hemorrhage].

8 cases of rhegmatogenous retinal detachment associated with vitreous hemorrhage were treated by first removing the blood through vitrectomy followed by routine retina reattachment procedures, such as searching for retinal breaks with indirect ophthalmoscopy and scleral buckling or encircling. Among 6 cases followed up, only 1 cases relapsed due to PVR traction. The points of note during operation were mentioned and the relationship between retinal breaks with vitreous hemorrhage and posterior vitreous detachment discussed.

Adult↗

[Vitrectomy plus air tamponade for treatment of retinal detachment with proliferative vitreoretinopathy].

Closed vitrectomy, membrane peeling, intraocular air tamponade and scleral encircling were performed for 35 consecutive cases of retinal detachment with proliferative vitreoretinopathy (PVR), comprising 2 cases of grade C2, 4 cases of grade C3, 6 cases of grade D1, 17 cases of grade D2, and 6 cases of grade D3. 21 eyes (60%) attained anatomic retinal reattachment with improved visual acuity in 20 eyes. The authors believed that vitrectomy combined with membrane peeling was a logical approach to the treatment of retinal detachment with PVR. The surgical success was related to the extent of membrane peeling, and intraocular air tamponade was a simple and effective adjunctive measure.

Adolescent↗

Gas tamponade as a single technique in the treatment of retinal detachment: is vitrectomy needed? A comparative study of 120 cases.

Internal gas tamponade is employed with no episcleral buckle and can be combined with or without a vitrectomy for the surgical treatment of some forms of retinal detachment. These techniques are for forms of retinal detachment with no proliferative vitreoretinopathy that are being operated upon for the first time and have one or several breaks located on the superior half of the retina. We compare these two techniques, their anatomical results, and their complications.

Cataract↗

Comparison of pneumatic retinopexy and scleral buckling in the management of primary rhegmatogenous retinal detachment. Southern Wisconsin Pneumatic Retinopexy Study Group.

PURPOSE: To compare pneumatic retinopexy and scleral buckling for repair of primary rhegmatogenous retinal detachment with respect to visual outcome, single-procedure reattachment rate, and development of proliferative vitreoretinopathy. METHODS: A consecutive series of eyes initially treated with pneumatic retinopexy (n = 56) between March 1986 and February 1996 were compared with a selected group of eyes treated with scleral buckling (n = 86) with similar location and distribution of retinal breaks and absence of proliferative vitreoretinopathy. A regression model was developed to adjust for underlying differences between treatment groups, resulting in a cohort of 50 eyes in each group for final comparison. A minimum follow-up of 6 months was obtained. RESULTS: Single-procedure reattachment rate was significantly higher for scleral buckle eyes (42 of 50 eyes, 84%) than for pneumatic retinopexy eyes (31 of 50 eyes, 62%; P < or = .01). Correspondingly, reoperation rate was significantly higher for pneumatic retinopexy eyes (19 of 50 eyes, 38%) than for scleral buckle eyes (7 of 50 eyes, 14%; P < or = .01). Multiple regression analysis evaluating perioperative factors demonstrated that the use of pneumatic retinopexy was the sole factor predictive of retinal detachment after a single procedure (relative odds = 2.20, P = .02). Final reattachment rate, after reoperations, was 98% (49 of 50 eyes) in each group. Except for nonphakic eyes, final visual outcome and rate of postoperative proliferative vitreoretinopathy development did not differ significantly between the two procedures. CONCLUSIONS: In phakic eyes, pneumatic retinopexy was associated with a significantly higher reoperation rate than scleral buckling, but resulted in equivalent final visual outcome and reattachment rate after reoperations. If used, it must be incorporated into a strategy in which patient and physician are prepared for a greater chance of reoperation compared to initial management with scleral buckling.

Cryosurgery↗

Randomized clinical trial of cryotherapy versus laser photocoagulation for retinopexy in conventional retinal detachment surgery.

PURPOSE: To investigate whether the method of retinopexy influences the visual recovery rate and the breakdown of the blood-ocular barrier after conventional retinal detachment surgery. METHODS: Forty-eight patients (48 eyes) with primary rhegmatogenous retinal detachment entered into the study. All eyes were phakic, had an attached macula, and were scheduled for conventional scleral buckling surgery. Patients were randomly assigned to have either laser or cryotherapy for retinopexy. All visual acuity and flare measurements were performed by a masked observer. The interventional procedure was cryopexy at the time of scleral buckling surgery or postoperative (4 weeks) laser photocoagulation. Visual acuity testing with ETDRS chart and aqueous flare measurement with laser flare photometry were performed by a masked observer at standard intervals: preoperatively and 1 day, 7 days, 4 weeks, and 10 weeks postoperatively. Analysis of covariance by multiple linear regression was used for statistical evaluation. RESULTS: Postoperative flare values from patients receiving cryotherapy were significantly higher at each measurement point in time (P < or =.001). The visual recovery was slower in the patients receiving cryotherapy (1 week, P =.003; 4 weeks, P =.03; 10 weeks, P =.081). CONCLUSION: Laser flare photometry proved sufficiently sensitive to quantify an increase in aqueous flare after limited external retinal cryotherapy. Postoperative flare, as a measure of blood-ocular barrier breakdown, was significantly higher and visual recovery slower in the cryotherapy group. Visual acuity after 10 weeks was not significantly different between both groups.

Blood-Retinal Barrier↗

[The value of an outpatient clinic for patients with retinal detachment].

The article reports on an outpatient department for retinal detachment patients established since 1972 in the First Eye Clinic in Vienna. Of the 225 patients treated up to 1978, 19 had a relapse, 9 patients were subjected to prophylactic retinopexy in the tear area which had not coagulated sufficiently, whereas in 15 cases latent tears were found in healed eyes and in 17 cases in the second eye. In two patients, beginning detachment in the second eye was detected at an early stage, whereas in two cases detachment occurred despite continual control. The article underlines the usefulness of this outpatient section for clinical and research work.

Aftercare↗

Sudden vision loss following retinal detachment surgery.

A 22-year-old man with Eales' disease with secondary rhegmatogenous retinal detachment with a break five disc diameters from the disc underwent radial scleral buckling using a silicone sponge episcleral explant with local cryopexy. Five hours after surgery the patient had no light perception. There was no intraoperative or postoperative rise of intraocular pressure or central retinal artery ischemia. Immediate removal of the explant brought a return of light perception and postoperative visual acuity improvement. The episcleral explant may have caused the direct optic nerve trauma that resulted in loss of vision.

Adult↗

[Long-lasting expansive gases in the treatment of rhegmatogenous retinal detachment associated with vitreoretinal proliferation].

Thirty two eyes of 32 patients affected with rhegmatogenous retinal detachment (R.D.) associated with proliferative vitreoretinopathy (P.V.R.) were operated on with combined external and endovitreal microsurgery. Internal tamponade was carried out with SF6 in 16 eyes and C3F8 in 16 eyes. All patients were followed for at least six months after the last surgical procedure. Permanent retinal reattachment was achieved in 56% of the eyes operated on with SF6 and 60% of the eyes operated on with C3F8. Surgical success was achieved with only one operation in those eyes operated on with C3F8. In contrast, 88% of the eyes successfully operated on with SF6, had more than one operation. The overall surgical results, whatever the gas used for internal tamponade, are as follows: surgical success was achieved in 83% of P.V.R. cases grade C1 and C2 (5 cases out of 6), 73% of P.V.R. cases grade C3 and D1 (11 cases out 15), and 20% of P.V.R. cases grade D2 and D3 (2 cases out of 10).

Adolescent↗

[Retinal detachment in patients with pseudophakia].

49 eyes with pseudophakic retinal detachments are operated with 44 good anatomic results (90% success). These detachments are characterised by the high frequency of anterior proliferative vitreoretinopathy.

Adult↗

Massive orbital cyst of the lateral rectus muscle after retinal detachment surgery.

A 73-year-old white man presented with painless proptosis of the right eye 18 years after retinal detachment surgery on the same eye. Computed tomography (CT) showed a mass in the area of the lateral rectus muscle and magnetic resonance imaging (MRI) defined the multiloculated cystic mass to be located within the lateral rectus muscle. At the time of surgery, a large, thin-walled cystic lesion was found within the lateral rectus muscle. Histopathologically, the cystic mass was of nonkeratinizing stratified squamous conjunctival epithelium. Massive orbital cysts after retinal detachment surgery are rare. The authors review the literature and comment on the differential diagnosis and presumed pathogenesis of this lesion.

Aged↗

Treatment of combined traction-rhegmatogenous retinal detachment in the morning glory syndrome.

A 14-year-old boy had a near total retinal detachment associated with the morning glory optic disc anomaly. A tiny slit-like retinal break with adjacent vitreous traction was found within the coloboma, providing communication between the vitreous cavity and the subretinal space. Vitrectomy, fluid-gas exchange, and postoperative confluent Krypton laser photocoagulation around the optic disc resulted in a successful reattachment of the retina. The retina has remained attached for 14 months.

Adolescent↗

Retinal detachment with intraocular lenses.

Of 740 patients undergoing intracapsular cataract extraction with intraocular lens implantation by the same surgeon, 18 (2.43) experienced retinal detachment. Analysis of the data of these 18 patients reveals:--the series covered 6.25 years (75 months).--there were 13 males and 5 females (72% males).--their average age at the time of cataract surgery was 63.--the median duration between cataract surgery and retinal detachment was 11 months. The shortest interval was 5 weeks, the longest was 39 months.--a predisposing fall was documented in 17%.--33% suffered vitreous loss at the time of cataract extraction.--of the 18 patients, 15 (83%) underwent retinopexy; of the remaining 3, one eye (6%) was not repairable and 2 patients (11%) refused detachment surgery.--only 6 (33%) of the 18 achieved useful post-detachment vision.

Aged↗

Long-standing retinal detachments--the role of internal tamponade.

Internal tamponade with gases or silicone-oil is useful in the management of long-standing retinal detachments complicated by retinal folds, posterior breaks or PVR and to close breaks after vitrectomy. Such complications and the needs for vitrectomy are particularly common in cases of persistent or recurrent long-standing detachment after unsuccessful retinal reattachment surgery.

Air↗

Time course of growth factor staining in a rabbit model of traumatic tractional retinal detachment.

BACKGROUND: This study examined the relationship between growth factor expression and cellular proliferation during the evolution of traumatic tractional retinal detachment (TRD) in a rabbit model. METHODS: TRD was induced in 15 pigmented rabbits by treating the inferior retina with cryopexy and making a scleral incision superiorly. Sections from varied time points were stained in the same assay with mouse monoclonal antibodies (MAb) specific for basic fibroblastic growth factor (bFGF) and platelet-derived growth factor (PDGF-BB/AB). RESULTS: Initially, the eyes exhibited intense vitritis; discrete membranes were present at 7 days and progressed to tractional retinal detachment at 17 and 28 days, after which there was no clinical change. At 6 and 24 h, bFGF, PDGF, and proliferating cell nuclear antigen (PCNA) were not detectable in membranes or wound sites (except for PDGF-positive inflammatory cells). On days 7, 17, 28, and 52, bFGF and PDGF were readily detectable in most membranes. Cellular proliferation as detected by PCNA staining was also present on days 7, 17, and 28, but was absent by day 52 despite growth factor staining. At all times, PCNA staining, which was most intense at the wound site, showed only limited correlation with staining for either growth factor for individual cells. Müller cells stained positively for PDGF-BB/AB in 13 of the 15 TRD eyes, but in none of the normal eyes. CONCLUSIONS: Since cellular proliferation correlated incompletely with the staining for bFGF and PDGF, these growth factors may not account exclusively for cellular proliferation within the membrane. Their distribution, however, including PDGF staining of Müller cells and bFGF staining at the vitreous-membrane interface, suggests that they may have roles in the pathogenesis of TRD.

Animals↗

[General anesthesia in surgery for retinal detachment (author's transl)].

A report on operations for retinal detachment performed under general anesthetic during the last five years. These were restricted to selected patients. If requirements regarding operating rooms and personnel can be satisfied, general anesthesia should be the general rule in retina surgery, neuroleptanalgesia being the ideal type of anesthesia.

Anesthesia, General↗

[Treatment of retinal detachment with a macular hole using the Convers-Machemer method].

Fourteen patients with retinal detachment and macular hole were treated by pars plana vitrectomy and air-gas injection, according to the method of Gonvers and Machemer. Neither scleral buckling procedures at the posterior pole nor coagulation of the macular hole were performed. Ten patients had not previously undergone detachment surgery, and the retinas were reattached in all of them at the follow-up examination 3 months later. In 2 patients the retina subsequently redetached, 7 and 14 months after surgery. Four patients had undergone detachment surgery previously; only in one of them was the retina still reattached after 3 months. The best postoperative visual acuity was 0.2, in 3 patients.

Adult↗

Perfluorocarbon liquid in the management of retinal detachment with proliferative vitreoretinopathy.

PURPOSE: To describe the techniques and results of perfluoro-N-octane used during vitrectomy for managing retinal detachment with severe proliferative vitreoretinopathy (PVR). METHODS: The authors retrospectively studied 223 consecutive patients who underwent vitreoretinal surgery for severe PVR (93% D1-D3). Patients underwent an average of 1.72 prior vitreoretinal surgeries. Perfluoro-N-octane was used intraoperatively to flatten the retina, avoiding posterior drainage retinotomy, to identify areas of residual retinal traction and periretinal membranes, to stabilize the peripheral retina during dissection of anterior PVR, and to help determine the extent and location of relaxing retinotomies. Extended-term gas tamponade was used in 91% of eyes. All patients were followed for a minimum of 6 months. RESULTS: Seventy-eight percent of the retinas were reattached posterior to the scleral buckle after a single vitreoretinal surgery and 96% were reattached after multiple surgeries. An average of 1.24 vitrectomy surgeries were required. The final visual acuity was 20/400 or better in 74% of eyes and 20/80 or better in 30% (P = 0.004). Preoperative hypotony (intraocular pressure < or = 5 mmHg) and multiple prior vitreoretinal surgeries were associated with a poor final visual acuity (P = 0.01 and 0.02, respectively). Preoperative hypotony (intraocular pressure < or = 5 mmHg) was associated with a greater frequency of relaxing retinotomies (P = 0.02). Retained perfluoro-N-octane was observed postoperatively in the vitreous cavity in 1.3% and subretinal perfluoro-N-octane in 0.9%. CONCLUSION: Experience with perfluoro-N-octane has demonstrated its usefulness both diagnostically and therapeutically as an intraoperative tool and improved the anatomic and visual outcome for retinal detachment complicated by severe PVR.

Adolescent↗