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At least 1,603 records · Page 89Linked to original sources
PubMed1993

[Unusual site of heterotopic ossification in the area of a laparotomy scar].

We report on a patient with spinal cord injury and an unusual localization of heterotopic ossification (HO) in the area of a laparotomy scar, with a large quantity of foreign bodies from residual suture material. This makes it obvious that extraskeletal cells can differentiate for osteogenesis. However, neither the mechanism of the induction process of HO nor the stimulating agents are precisely known. It must be stressed, however, that the occurrence of HO can be influenced by foreign bodies in the presence of favourable microenvironmental conditions.

Abdominal Injuries↗
PubMed1994

Heterotopic ossification after primary cemented and noncemented total hip arthroplasty in patients with osteoarthritis and rheumatoid arthritis.

OBJECTIVE: To compare the frequency and severity of heterotopic ossification (HO) in patients with osteoarthritis or rheumatoid arthritis who undergo cemented or noncemented total hip arthroplasty. DESIGN: A prospective case study. SETTING: A university referral centre. PATIENTS: One hundred and sixty one patients underwent 184 total hip arthroplasties. The 184 hips were categorized as follows: cemented total hip arthroplasty--60 osteoarthritis hips, 26 hips affected by rheumatoid arthritis; noncemented total hip arthroplasty--67 osteoarthritic hips, 31 hips affected by rheumatoid arthritis. INTERVENTIONS: Total hip arthroplasty. A standard approach was used to implant either a cemented or noncemented prosthesis. Radiographs were obtained of each hip preoperatively, immediately postoperatively and 6 weeks, 3 months, 6 months and 1 year postoperatively. MAIN OUTCOME MEASURES: Radiographs were graded in blind fashion for HO, according to the criteria of Brooker. Modified Harris hip scores were calculated at 1 and 2 years postoperatively. RESULTS: HO (incidence of Brooker grades 2, 3 and 4) was greater after cemented (22%) than noncemented (9%) total hip arthroplasty in osteoarthritic hips (p < 0.05), but there was no significant difference between the two types of prosthesis in hips affected by rheumatoid arthritis. When both types of prosthesis were considered together there was no significant difference in the incidence of HO between osteoarthritic hips (15%) and hips affected by rheumatoid arthritis (12%). With respect to Harris hip score, the presence of grade 4 HO was associated with a significantly (p < 0.05) lower score (50.6) than grade 3 (89.4) and grade 2 (91) HO. CONCLUSIONS: Cemented total hip arthroplasty increases the frequency of HO only in osteoarthritic hips. Compared with Brooker's grades 2 and 3 HO, grade 4 HO significantly lowers the Harris hip score after total hip arthroplasty.

Adult↗
PubMed1975

[Pneumopathia osteoplastica (pulmonary ossification) (author's transl)].

The Pneumopathia osteoplastica is a rare disease manifesting in two different forms of appearance. The tuberous (nodular) ossification affects mainly younger persons and is resulting in the great majority from chronic congestion of the lung due to mitral stenosis. Compared to it the idiopathic racemose (ramified) form affects older males. The paper is based on 9 cases of the two morphologic variants. The clinical aspects, etiologym morphology, and differential diagnosis of them are discussed with regard to newer publications.

Adult↗
PubMed1993

Postsurgical radiation therapy for prophylaxis of heterotopic ossification.

Radiation therapy has been shown to be the most effective prophylactic measure against heterotopic ossification (HO) in surgically repaired hip fractures. Current research is seeking the minimum effective dose of radiation. The authors present four case reports and a review of the literature on HO.

Adult↗
PubMed1976

The role of scintigraphy in the diagnosis of late complications of total prosthesis of the hip. (Infection, loosening, ossification).

Late bony infection is the most important post operative complication of total prosthesis. It is an insidiuos and often silent process, and early diagnosis is the most effective weapon for controlling it. Scintigraphy with osteotropic isotopes is a valuable diagnostic aid. It can give information even before the appearance of any radiographic changes, and can establish which component is affected in a total prosthetic replacement. It is also of help in the differential diagnosis between infection and loosening. Finally, it is a useful criterion in evaluating the progression of ectopic ossification.

Bacterial Infections↗
PubMed1993

Ossification of human thyroid cartilage. Scanning electron microscopic study.

The architecture of the cartilage already developed within ossified areas have shown apparent differences not only depending on their location within cartilage territory but also due to their chemical composition. The cartilage areas exhibiting a markedly advanced ossification process have shown rather high concentration level of Ca, P and Si.

Adult↗
PubMed1993

Heterotopic ossification in colorectal adenocarcinoma [corrected].

Heterotopic ossification in Adenocarcinomas of the colon is uncommon. The clinical presentation of these patients is similar to those without osseous metaplasia. Its importance lies in the fact that it may be misdiagnosed for a carcinosarcoma. Which has a poorer prognosis. These two cases are reported because of its rarity.

Adenocarcinoma↗
PubMed1993

Cervical myelopathy secondary to ossification of the posterior longitudinal ligament in a Caucasian patient.

Cervical myelopathy consequent on ossification of posterior longitudinal ligament (OPLL) is very rare in Caucasians. A 65-year-old Anglo-Saxon woman developed progressive gait disturbance, paresthesia in both legs and urinary urge incontinence. Radiological examination showed OPLL from fifth to seventh cervical vertebral level; the dense OPLL was graphically displayed by three-dimensional computerized tomography. Medial corpectomy, C5 to C7, and removal of OPLL, with subsequent fusion C4 to T1 using a free fibula graft resulted in clinical improvement. Three dimensional computerized tomographic imaging is a valuable diagnostic procedure in OPLL.

Aged↗
PubMed1993

Early removal of periarticular ossifications in patients with head injury.

Heterotopic ossifications are a well known but serious complication in patients suffering severe head injury. Their prevalence varies between 10% and 20%. The current concept of surgery recommends removal after "maturation" of the new developed bone because of a suspected higher rate of recurrence. The observations of early operations in 6 patients and 9 joints led us to the conclusion that the disadvantages of long lasting joint stiffness and the according complications outweigh the danger of recurrence. In our patients recurrence was observed in one subject and even there recurrence was most probably the result of wound infection and concomitant osteomyelitis.

Adolescent↗
PubMedDate not supplied

Heterotopic ossification.

Heterotopic ossification is well recognized following trauma to the head and spinal cord, total hip arthroplasty and internal fixation of acetabular fractures. Fortunately, effective prophylactic measures exist to minimize this occasionally devastating complication. This article reviews the pathophysiological events involved in heterotopic bone formation and outlines its clinical presentation and management.

Alkaline Phosphatase↗
PubMedDate not supplied

Observations on symptomatic medial malleolar ossification centers.

We report 11 cases of symptomatic medial malleolar ossification centers (MMOC). Symptoms in six of the 10 patients responded to diminished athletic activity. Four patients required short-leg walking casts, and two of these patients required repeat casting for symptom recurrence. Two groups of bilateral, three-view ankle roentgenograms of asymptomatic patients were reviewed to determine the incidence of MMOC. Group 1 (age 6 years 1 month to 12 years 11 months) had a 20% incidence, and group 2 (age 13 years 1 month to 17 years 11 months) had a 4% incidence. Symptoms may occur at these roentgenographic variants, and diminished activity, either volition or enforced by walking casts, produced resolution of symptoms in all patients.

Adolescent↗
PubMed1993

Dysphagia complications in ankylosing spinal hyperostosis and ossification of the posterior longitudinal ligament. Roentgenographic findings of the developmental process of cervical osteophytes causing dysphagia.

This is the first report of the process of formulation of a cervical osteophyte causing dysphagia. The patient had ankylosing spinal hyperostosis and OPLL and was followed radiographically for a long time before the onset of dysphagia. The radiological observation suggested that dysphagia was produced when the immobile part of the esophagus was compressed by the anterior projecting cervical osteophyte. The immobility of the esophagus is an important factor in determining whether dysphagia occurs. Another possible contributing factor to dysphagia in this patient was the ossification of the cervical anterior and posterior longitudinal ligaments. The OPLL affected intervertebral segmental motion and induced the formation of anterior projecting cervical osteophytes.

Adult↗
PubMedDate not supplied

Histochemical and immunohistochemical study on the skin of patients with ossification of the posterior longitudinal ligament in the cervical spine.

We present an immunohistochemical study on extracellular matrix (ECM), decorin, in the epidermis and dermis of patients with ossification of the posterior longitudinal ligament (OPLL) to clarify the abnormality in the extracellular matrix of the skin of OPLL. Localization of decorin and TGF-beta in the skin was studied. All patients with OPLL showed a diffuse strong staining of decorin in the entire epidermal layer. The epidermis was also positive for TGF-beta antibody staining. Patients with cervical spondylotic myelopathy showed weak or no staining of decorin. Abnormality in the regulating system of TGF-beta may be involved in the precipitation of extracellular matrix.

Aged↗
PubMed1995

[Cervical spinal cord compression caused by ossification of the posterior vertebral ligament. Apropos of a case].

Progressive cervical myelopathy due to an ossification of the posterior longitudinal ligament (OPLL) appeared in a sicilian women. Diagnosis was made by lateral conventional tomograms and CT Scan with mielography. Corporectomy of the 5th vertebra and ablation of the ligament dramatically improved the clinical symptoms. If OPLL seems a common cause of cervical myelopathy in Japan, it is very rate in Caucasian people. Instead of the origin of the patients, progressive tetraparesis of the 60 years old people is the usual presentation of this affection. The cause of OPLL remains unknown: genetic factors, vitamin A, association with diffuse idiopathic skeletal hyperostosis, calcium metabolism abnormalities are discussed. As far as surgical treatment is concerned, choice between anterior and posterior decompression is clarified on the basis of the type and the extension of OPLL.

Adult↗
PubMed1995

Periarticular heterotopic ossification: a complication of arthroscopic anterior cruciate ligament reconstruction using a two-incision technique.

Extra-articular heterotopic bone formation was recognized as a postoperative complication of arthroscopic anterior cruciate ligament reconstructions in four knees around the femoral drill hole. Although laxity of the reconstructed anterior cruciate ligament was not observed in these patients, local pain, swelling, and deformity at the site of heterotopic ossification required surgical intervention. The ectopic bone can be successfully excised with restoration of function. The incidence rate of this complication is less than 1%.

Anterior Cruciate Ligament↗