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At least 1,603 records · Page 89Linked to original sources
PubMed1985

Serologic studies of erythema chronicum migrans Afzelius and acrodermatitis chronica atrophicans with indirect immunofluorescence and enzyme-linked immunosorbent assays.

To determine whether antibodies to Borrelia spirochetes were present, sera from 88 patients with uncomplicated erythema chronicum migrans Afzelius (ECMA), from 9 patients with ECMA-related extracutaneous complications and from 26 patients with acrodermatitis chronica atrophicans (ACA) were submitted to an enzyme-linked immunosorbent assay (ELISA) and an indirect immunofluorescence (IF) assay. The assays were calculated to be 95% specific. There was good correlation between the IF test with a polyvalent conjugate and IgG ELISA. Of patients with uncomplicated ECMA, 18% were seropositive by IgG ELISA and 11% by IgM ELISA, and 15% showed elevated IF titers. Elevated serum antibody levels of IgG as measured by ELISA and elevated IF titers were found in all patients with extracutaneous complications and in the patients with ACA. Declining IgG titers were observed at follow-up 6-12 months after therapy, but the majority of the patients with ACA were still seropositive.

Acrodermatitis↗
PubMed1986

Erythema elevatum diutinum and pre-AIDS.

Erythema elevatum diutinum (EED) is a chronic disease with symmetrical persistent erythematous nodules and plaques primarily in an acral distribution. EED is often associated with infections, especially of streptococcals. An immunological reaction has been proposed as pathogenetic mechanism. We describe a patient, who developed EED secondary to a LAV/HTLV III positive lymphadenopathy syndrome. Immunological investigation of a skin lesion and a lymph node biopsy is described.

Adult↗
PubMed1989

[Erythema ab igne].

Erythema ab igne (EAI) has not been common since coal stoves have no longer been in general use for heating. Nevertheless, each winter several patients with macular-reticular skin lesions considered to be EAI are seen in our clinic. Correct diagnosis depends on awareness of the condition. 3 women, aged 17, 34 and 50, respectively, in whom EAI was induced by prolonged sitting close to an electrical heating device are presented. When this was discontinued the skin lesions disappeared. In the majority of reported cases of EAI the course was benign, similar to that in our patients in whom there were no additional related lesions. However, isolated cases of squamous cell carcinoma developing in patients with EAI have been described. In other cases the local heating which caused the EAI was applied for relief of pain and the appearance of EAI was the first clue to an underlying internal disease.

Adolescent↗
PubMed1989

[Erythema chronicum migrans and Lyme's disease].

A 66 year old woman with a history suggesting a tick bite on the right arm developed a slowly expanding erythematosus lesion. Similar lesions appeared on the trunk and extremities in the following months. A skin biopsy showing spiral shaped agents and the clinical findings were compatible with erythema chronicum migrans. A course of penicillin resulted in complete resolution of the lesions. After a 2 year follow up period she remains free of rheumatic, neurologic or cardiac lesions of Lyme's disease.

Aged↗
PubMedDate not supplied

Acral erythema during bone marrow transplantation: a case study.

Six of 13 patients receiving high-dose cytosine arabinoside as preparation for bone marrow transplant experienced painful redness and blistering of the hands and feet. Literature reports described this syndrome in patients receiving high-dose chemotherapy but at lower rates of occurrence than in this series of patients. Nursing problems encountered in patients experiencing acral erythema included: pain, compromised self-care, decreased activity, and infection potential. Nursing measures for dealing with these problems are described.

Bone Marrow Transplantation↗
PubMed1989

[Meningoencephalomyelitis caused by Borrelia burgdorferi: a case without epidemiologic history or chronic migratory erythema].

A patient is reported with meningoencephalomyelitis with polyradiculitis caused by Borrelia burgdorferi infection. Neurological features developed without previously known tick bite nor the characteristic skin lesion, chronic migratory erythema (CME). The vector of the disease (the tick Ixodes ricinus) exists in Spain, but only one case of meningopolyradiculitis with CME has been reported in Asturias. Our case stresses that B. burgdorferi infection should be suspected in cases of meningoencephalomyelitis or meningopolyradiculitis even without previous skin or joint lesion.

Adult↗
PubMedDate not supplied

Erythema multiforme, potential complicating factor in dental therapy.

Erythema Multiforme, (E.M.) is an interesting dermatologic disease which has oral manifestations. It presents a diagnostic dilemma because the oral cavity has the ability to produce varied manifestations. The range of possible etiologies fo oral disease is immense. Therefore, the dentist must have a differential diagnosis for all oral lesions. The following case report represents a differential diagnosis problem which hampered routine dental therapy. The oral soft tissue lesions needed to be managed before the endodontic therapy could be completed.

Adult↗
PubMed1989

[Borrelia burgdorferi, clinical aspects, cultivation and identification of the pathogen in erythema migrans in Berlin].

Among other manifestations, the following diseases caused by Borrelia burgdorferi in Europe are transmitted by ticks of the species ixodes ricinus: erythema migrans (EM), lymphadenosis benigna cutis (LBC), lymphocytic meningo-radiculitis (Bannwarth's syndrome), and acrodermatitis chronica atrophicans (ACA). We report on a female patient, who developed EM 10 days after a-tick bite in Berlin. Borrelia burgdorferi could be cultivated from a skin biopsy specimen taken from the periphery of the EM. The isolates were identified as Borrelia burgdorferi by indirect immunofluorescence using the monoclonal antibodies H 9724 and H 5332.

Animals↗
PubMed1989

[Two cases of squamous cell carcinoma arising from erythema ab igne].

This report describes two female patients, 69 and 79 years old, with squamous cell carcinoma (SCC) developing from erythema ab igne (EAI) due to thermal irradiation from a sunken hearth (irori in Japanese) or an underfloor brazier covered with a quilt (kotatsu in Japanese). EAI on the knees and lower thighs showed reticular pigmentation at its periphery and poikiloderma in the center with many keratotic nodules. In both cases, the SCCs were located almost symmetrically on an anterior site 1/3 of the way down both lower thighs. They were surrounded by many keratotic nodules. Histologically, these nodules showed an atypia of the epidermal cells, indicating carcinoma in situ resembling actinic keratosis ro Bowen's disease. It was also strongly suggested that the SCCs in these patients had developed from the keratotic nodules. EAI appeared to have played a pathogenetic role in the cutaneous carcinoma.

Aged↗
PubMed1989

[Erythema nodosum: epidemiology, etiology, pathogenesis, clinical picture and therapy].

Erythema Nodosum (EN) is a painful nodular syndrome, most likely of immunologic origin, which involves dermis and subcutaneous tissue. Pathologic process is that of vasculitis of the small veins with inflammation of the septa of the fat lobules (septal panniculitis). It is generally agreed that EN represents a hypersensitive reaction to a variety of antigenic stimuli and thus may be observed in the course of several diseases (infections, immunopathies, malignancies) as well as during drug therapy (with halides, sulfonamides, oral contraceptives). In approximately 50 per cent of the cases an underlying etiology is not apparent (idiopathic form). The clinical picture is always that of a nonspecific systemic illness with low-grade fever (in 60%), malaise (in 67%), arthralgias (in 64%) and arthritis (in 31%), while when there is an associated illness, this may dominate the presentation. Laboratory tests show no specific abnormalities except for those related to an underlying disease. Treatment of idiopathic form includes nonsteroidal antiinflammatory agents which usually ease the discomfort. Steroids, although highly effective, are not recommended because of the benign nature of EN and the danger of disseminating an underlying disease.

Erythema Nodosum↗
PubMed1989

Erythema chronicum migrans as the presenting manifestation of juvenile chronic myelocytic leukemia.

We describe the case of a 3-year-old boy who presented with typical clinical features of Lyme disease, including erythema chronicum migrans and arthritis. Over subsequent months, however, the clinical picture evolved into juvenile chronic myelocytic leukemia. To our knowledge, the combination of Lyme disease and juvenile chronic myelocytic leukemia has not been described. Dermatologic and other relevant clinical findings are presented, and the cause and effect relationship between these two rare entities is discussed.

Child, Preschool↗
PubMed1989

Reaction to UV-induced erythema in young patients with basal cell carcinoma.

The effects of an irradiation 6 times the minimal erythemal dose of UVB were studied using a visual scale from 1 to 4+ in 12 patients aged under 45 years with a past medical history of basal cell carcinoma, and in 12 sex-, age- and skin-type-matched controls. Erythema was significantly more intense at days 15 (p less than 0.01) and 22 (p less than 0.001) in patients than in controls. Pigmentation was significantly weaker at day 22 than in controls (p less than 0.005).

Adult↗
PubMed1989

Erythema multiforme following cardizem therapy: report of a case.

A 63-year-old male developed severe, painful ulcerations shortly after beginning therapy for angina with diltiazem (Cardizem). Erythema multiforme is a common adverse reaction to medications. The case report, as well as the role of the dentist in diagnosis and management of these clinical presentations, is discussed.

Diltiazem↗
PubMed1989

A transient rise in agalactosyl IgG correlating with free interleukin 2 receptors, during episodes of erythema nodosum leprosum.

The proportion of oligosaccharide chains on the Fc fragment of IgG which terminate with N-acetylglucosamine and not galactose (%GO) has previously been shown to be raised in rheumatoid arthritis (RA), Crohn's disease (CD) and tuberculosis (Tb), but to be normal in sarcoidosis (SA), and in both lepromatous and tuberculoid leprosy. However we have now studied %GO in sequential serum samples collected from lepromatous leprosy patients undergoing episodes of erythema nodosum leprosum (ENL). During ENL %GO is transiently raised, and this rise parallels an increase in circulating interleukin 2 receptors (IL-2R). These findings confirm that changes in T cell function occur during ENL. Moreover it appears that %GO rises when there is, simultaneously, T-cell-mediated tissue damage and an acute phase response (RA, CD, Tb, ENL), but not when there is an acute phase response without major T cell involvement, or chronic T cell activity alone (SA, and tuberculoid leprosy). We suggest therefore that %GO is an indicator of a type of T cell activity with broad immunopathological implications.

Acetylglucosamine↗