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At least 1,585 records · Page 88Linked to original sources
PubMed1993

Natural history and visual outcome in patients with APMPPE.

We undertook a retrospective study of the files of 21 patients (42 affected eyes) with acute posterior multifocal placoid pigment epitheliopathy to obtain details on the natural history of the disease and on the functional and visual outcome (mean follow up: 17 months). The final visual acuities were 8/10 or better in 34 eyes (81.0%), 7/10 to 2/10 in 6 eyes (14.2%) and 1/10 in two eyes (4.8%). Although the final visual acuity was good in most eyes, 24 eyes (57.2%) were still symptomatic due to scotomas (33.3%), metamorphosia (21.4%), decreased vision (16.6%), floaters (4.8%) and chronic redness (2.4%). Recurrences did not occur in this group of patients. Electrophysiological and color vision tests were performed in the initial phase of the disease, but we found no correlation between the test results and the final visual acuity.

Adolescent↗
PubMed1993

Systematic literature review for clinical practice guideline development.

The purpose of this paper was to evaluate the quality and scope of the published literature on functional impairment due to cataract in adults as reviewed for the Agency for Health Care Policy and Research Clinical Practice Guideline. We examined the method of literature retrieved and analysis performed in the course of development of literature-based recommendations for the guideline panel. To collect data, we reviewed the process of literature acquisition and identification and the quality assessments made by reviewers of 14 individual topics composed of 77 issues related to the guideline. We collated this information to provide an assessment of the quality and scope of the relevant literature. Less than 4% (310) of the approximately 8,000 articles initially identified as potentially relevant to the guideline were ultimately used. The majority covered three topics (surgery and complication, 100; Nd:YAG capsulotomy, 77; and potential vision testing, 40). Three other topics--indications for surgery, preoperative medical evaluation, and rehabilitation--were devoid of articles meeting inclusion criteria. For 43 issues, there was no identifiable relevant literature. With few exceptions, the quality of the literature was rated fair to poor owing to major flaws in experimental design. Case series (256 reports) of one type or another accounted for the majority of the included literature. There were 17 random controlled trials. This review revealed a sparse and generally low-quality literature relevant to the management of functional impairment due to cataract, despite a relatively large data base in reputable peer-reviewed journals.

Adult↗
PubMed1993

Hexadecylphosphocholine may produce reversible functional defects of the retinal pigment epithelium.

Hexadecylphosphocholine is a synthetic phospholipid derivative that has antitumor activity due to its interference with membrane functions. Animal experiments have shown photoreceptor and retinal pigment epithelium (RPE) degeneration after its systemic application. In a phase II trial of hexadecylphosphocholine therapy in 23 patients with advanced metastatic colorectal or lung cancer, visual acuity and color vision testing, slit-lamp examination, tonometry, fundoscopy (including photodocumentation), visual field testing, electrooculography (EOG), and electroretinography (ERG) were performed. A baseline examination was carried out prior to therapy. Patients were reexamined after 2 months and after 5 months. In all, 71% of the patients had a reduced light peak in the EOG during therapy. After the end of therapy the light peak improved again and became normal in most patients. The statistical analysis showed that the light-peak values during therapy were significantly lower than the baseline and posttreatment values. This indicates that hexadecylphosphocholine might be capable of producing a partly reversible functional defect of the RPE. Apart from this finding, no other functional or morphological ocular side effect was detected. The functional changes observed in our patients as well as the morphological changes found in animal experiments are similar to those reported for known diseases of the RPE-photoreceptor complex. Therefore, hexadecylphosphocholine-induced retinopathy might become useful as an animal model for such diseases.

Adenocarcinoma↗
PubMed1993

Assessing visual function in the older driver.

It is likely that some older adults will have to be restricted from driving because of serious and irreversible deterioration in skills crucial to driving, due to vision impairment, visual attention deficits, and decreased cognitive status; however many older adults with driving difficulties can improve their driving skills or reduce their crash risk through education or training programs. Research to evaluate interventions such as those previously mentioned has high priority, given society's need to maintain the mobility and personal independence of older adults without sacrificing safety concerns.

Accidents, Traffic↗
PubMed1995

Studies on development of visual acuity in infants measured by the Teller Acuity Cards.

In order to confirm the reproducibility of visual acuity measurements in infants and to elucidate the cause of the plateau and decrease in the developmental curve between the ages of 9 and 15 months, we have retrospectively studied visual acuity measured by the Teller Acuity Cards (TAC) in infants aged 2 to 28 months. The visual acuity measured by TAC was higher than that obtained by the conventional preferential looking (PL) method in infants until the age of 14 months. No statistically significant difference was observed between the first eye and the second (fellow) eye measurements. Although monocular visual acuity decreased in infants aged from 9 to 12 months, binocular visual acuity showed an increase in the same age group. The first binocular measurement was better than the last binocular measurement on the same day. Although the first binocular measurement showed an increase in infants aged from 9 to 15 months, the second binocular measurement decreased in the same age group. Our results suggest that all these phenomena mentioned above are likely to be due to the psychological or behavioral rejection to the examinations.

Child Development↗
PubMed1995

The Waterloo Vision and Mobility Study: postural control strategies in subjects with ARM.

Binocular vision function and standing balance control was assessed in 16 subjects with age-related maculopathy (ARM) (mean age 73.9 +/- 7.4 years) and 19 controls (mean age 69.1 +/- 5.5 years). Balance control was assessed using the center of pressure signal from force plate data. It was quantified using the root mean square (RMS) error of the amplitude, sampled over a 1 min period. This was evaluated during normal standing, and while the input from the kinesthetic and/or visual systems were disrupted. The two subject groups showed significantly different RMS values across conditions (P < 0.005). The differences in RMS between ARM and control groups were only significant when the input to the kinesthetic sensory system was disrupted. Our results suggest that in the normal standing condition, the kinesthetic and vestibular systems compensated for the lack of useful information from the visual system in ARM subjects. When kinesthetic system input was disrupted, balance control of the ARM group was significantly poorer than the control. There was a weak correlation between postural control and contrast sensitivity. Various strategies for preventing falls in elderly patients with low vision are suggested.

Aged↗
PubMed1996

Psychophysics of reading. XV: Font effects in normal and low vision.

PURPOSE: Little is known about the effect of font on low-vision reading. In this study, the authors measured the influence of font in reading with normal and low vision. METHODS: Reading acuity, maximum reading speed, and critical print size (the smallest print that can be read with maximum speed) were measured in 50 normal subjects and 42 subjects with low vision. Data were collected using versions of the MNREAD Acuity Chart printed with the Times (proportionally spaced) and Courier (fixed-width) fonts. RESULTS: Reading acuity scores obtained with Courier were better than those obtained with Times for both normal (mean difference, 0.05 logMAR, P < 0.001) and subjects with low vision (0.09 logMAR, P < 0.001). Similarly, critical print sizes measured with Courier were smaller than those measured with Times (mean difference, 0.06 logMAR for normal subjects and subjects with low vision, P < 0.002). Maximum reading speeds for normal subjects were 5% faster with Times than with Courier (P < 0.001), but for subjects with low vision, maximum reading speeds were 10% slower with Times than with Courier (P < 0.05). For print smaller than the critical print size, the reading speeds of normal subjects and subjects with low vision were substantially slower (by as much as 50%) for Times than for Courier. CONCLUSIONS: There are small, but significant, advantages of Courier over Times in reading acuity, critical print size, and reading speed for subjects with low vision. For normal subjects, the differences are slighter, with an advantage in reading speed for Times. However, for print sizes close to the acuity limit, choice of font could make a significant difference in both normal and low-vision reading performance.

Adult↗
PubMed1996

[State of binocular vision and comparative assessment of methods of its study in motor vehicle drivers].

Ophthalmologic study covered 100 truck drivers (categories C and E according to International Classification) aged 21 to 50 and with length of service from 2 to 25 years. Comparative evaluation of various methods studying deep and stereoscopic vision proved that professional drivers have high values of deep and stereoscopic vision. Those values appeared to correlate strongly and positively (r = 0.57). Making a decision on adequacy to driving the stated vehicles, experts should prefer simple and informative method studying stereoscopic vision through lens stereoscope with "three circles" table.

Adult↗
PubMed1996

[Delayed visual maturation--a differential diagnostic challenge. A follow-up study of 13 children with delayed visual development with or without other developmental disorders].

Early visual impairment represents several diagnostic possibilities from specific delayed visual maturation (type 1) with an excellent prognosis to more complex conditions with other ocular or neurological signs (type 2-4). Visual attention and interaction has been an interesting field of study in the interaction between biologically pre-programmed neonatal competencies and social facilitation. From these studies we can probably learn more about ((cloudy)) diagnoses such as cortical visual impairment, attention deficit hyperactivity disorder and autism. Investigations and follow-up of 13 infants who did not show any visual interest at 6 - 12 weeks old are presented, along with proposals for the clinical management of these problems.

Developmental Disabilities↗
PubMed1997

Association between visual reaction time and batting, fielding, and earned run averages among players of the Southern Baseball League.

BACKGROUND: This study was performed to investigate the relationship between vision reaction time (VRT) and batting, fielding, and pitching skill in baseball. METHODS: A vision screening of 213 professional baseball players in the Southern Baseball League was performed, and the visual reaction times of these players were determined. Official Southern Baseball League statistics were consulted to obtain the players' batting average, fielding average, and earned run average. RESULTS: The mean visual reaction time for all players was 239 msec. There was no significant association between mean VRT and age or race. The mean VRT for dominant eyes was not significantly different from the mean VRT for nondominant eyes. For the 92 players who batted at least 100 times, an association was found between mean VRT and batting average (p = 0.017). For the 168 fielders in the league playing at least 20 games, no statistically significant association was found between mean VRT and fielding average. Similarly, no association was found between mean VRT and earned run average for the B8 pitchers who had participated in more than 20 games. CONCLUSIONS: An association was found between visual reaction time and batting skill in baseball. No association was found between visual reaction time and fielding or pitching skill.

Baseball↗
PubMed1977

Binocular interactions in the human visual evoked potential after short-term occlusion and anisometropia.

The human visual evoked potential was recorded during 9 hr. of monocular occlusion or deprivation of fine detail by anisometropia. Some decrement in the response from the occluded eye was evident, but the major result was a sustained increase in the response from the nonoccluded eye. The anisometropic condition produced no decrement for stimulation of the deprived eye, but again there was an increase in the response from the nondeprived eye. Under some conditions the changes became apparent after only 6 hr. of deprivation. The data may be interpreted in terms of binocular competition or reciprocal inhibition at the level of the visual cortex or lateral geniculate nucleus.

Evoked Potentials↗