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At least 1,585 records · Page 88Linked to original sources
PubMed1991

[BRACS--a method for cephalometric diagnosis and orthodontic treatment planning. Biometric radiographic analysis of the craniofacial skeleton].

The BRACS (the biometric radiographic analysis of the craniofacial skeleton) is a mathematically originated method for diagnosing malocclusion and planning orthodontic treatment. In the conventional cephalometrics, the measurements are to be made in an unstable reference frame without any definable direction or coordinate system. When using the BRACS, the natural reference structures can be replaced by an artificial stable reference system. The procedure is introduced in this paper.

Cephalometry↗
PubMed1997

[Correlations between cribra orbitalia, archeometric findings on the skeleton and habitat conditions].

The interpretation of cribra orbitalia as an isolated skeletal lesion is mainly based on malnutrition, in particular in terms of iron deficiency or vitamin C deficiency. A chronic iron deficiency anemia should result in both a reduced iron content of the skeleton and an underhydroxylation of the amino acid proline with the consequence of a less stable collagen matrix of the bone. The latter holds also for a vitamin C deficiency. Trace element and amino acid analyses were independently applied to subsamples of two early medieval human skeletal series to test whether a relation between cribra orbitalia and skeletal iron content and amino acid hydroxylation was detectable. For one of these series (Nusplingen, district Balingen, Schwäbische A1b), habitat specific properties have already been assumed to be responsible for an insufficient iron supply of the inhabitants. Both archaeometric approaches led to a verification of the malnutrition hypothesis, but for advanced states of the skeletal lesion only. Less affected individuals did not reveal any of the expected relationships. Possible adaptive subsistence strategies are discussed which might compensate for such unfavourable living conditions.

Amino Acids↗
PubMed1976

A descriptive study of the rate of elongation and differentiation of the skeleton of the developing chick wing.

Differentiation of the wing skeleton is clearly visible in whole mounts from stage 24. It proceeds in proximo-distal and postero-anterior sequence. It is possible to map the part of the limb giving rise to each skeletal element as it appears and subsequently. This enables one to estimate: (a) a rate of elongation curve for each segment level, (b) the intrinsic rate of change of elongation of the cartilage, (c) a definitive extrapolation back to classical presumptive fate maps, (d) the normal range of variation in the proportion of the limb occupied by the three main segmental levels (stylopod, autopod, zeugopod).

Animals↗
PubMedDate not supplied

Bone formation with discs or particles of natural coral skeleton plus polyglactin 910 mesh: histologic evaluation in rat calvaria.

Several procedures have been used to regenerate localized bone defects around dental implants or to increase bone volume at an implant site, including bone grafting, placement of barrier membranes, and use of bone graft substitutes. This study sought to determine whether the bone graft substitute natural coral skeleton (NCS), with or without a protective polymer mesh, enhances bone formation in rat critical size craniotomy defects. The control group (1) had unfilled defects, while the defects in the four experimental groups (six rats each) were treated with: (2) an NCS disc of the size of the defect; (3) NCS granules; (4) NCS granules covered by a polyglactin 910 mesh; and (5) polyglactin 910 mesh alone. Undecalcified histologic sections were assessed by histomorphometric measurements 28 days later. The three NCS groups showed improved bone formation, which was statistically significant in groups (2) (NCS disc) and (4) (NCS granules covered by polyglactin 910 mesh). Group 4 had more bone formation than all the other groups. Polyglactin 910 mesh alone (group 5) produced no greater bone formation than the unfilled control. It is concluded that the bone formation obtained with NCS granules is enhanced when the particles are retained at the site of the defect with a protective mesh.

Animals↗
PubMed1976

[Cartilaginous tumors of the skeleton].

Chondrogenic tumors of the skeleton are divided into 6 separate groups: 1. chondroblastomas 2. chondromyxoidfibromas, 3. osteochondromas (cartilaginous exostoses), 4. enchondromas, 5. periostal chondromas, and 6. chondrosarcomas. The presentation of the different types of tumors demonstrates the pathogenesis, pathology, clinical findings, treatment, and prognosis. States of tumors before and after operative treatment are illustrated.

Aged↗
PubMed1998

Ectopic hematopoietic bone marrow in the appendicular skeleton after trauma.

METHODS: Combined bone scanning and immunoscintigraphy (IS) with 99mTc-monoclonal antigranulocyte antibodies were performed in two patients with suspected reactivation of chronic osteomyelitis of the lower extremity. Because bone scanning and IS were strongly positive, both patients underwent surgical intervention. RESULTS: Macroscopic findings did not show purulent infection and microbiologic results remained negative, but histology revealed unexpected ectopic bone marrow, explaining the strong uptake on IS. One patient exhibited active hematopoietic bone marrow at the former fracture site of the tibial bone. The second patient presented with interspersed bone marrow in the cortical bone of the femoral diaphysis after several intramedullary surgical procedures. CONCLUSION: Unexpected ectopic hematopoietic marrow may occur in the appendicular skeleton after trauma and repeated surgical interventions. The bone marrow shows a physiologic uptake with IS and may be misinterpreted as granulocyte accumulation due to infection. This may lead to false-positive diagnosis in cases of suspected osteomyelitis.

Adult↗
PubMedDate not supplied

[The ultrastructural changes in the collagenous-elastic skeleton of the wall of the cerebral vessels in spasm in the acute period of a subarachnoid hemorrhage].

Electron microscopic study of arteries in spasm and ischemia of the brain revealed substantial ultrastructural changes in the vascular wall. The changes are characterized by varying thickness, edema, dissociation of fibrillar and amorphous components of internal elastic membrane of the arterial wall, by lesion in the network of collagen fibers on its inner surface, by the presence of defibrotic and uncoiled collagenous fibers of the adventitia. The changes are followed by the impairment of the arterial skeleton and hence they lead to their altered elastic properties.

Acute Disease↗
PubMed1999

The role of the intergeniculate leaflet in entrainment of circadian rhythms to a skeleton photoperiod.

Mammalian circadian rhythms are synchronized to environmental light/dark (LD) cycles via daily phase resetting of the circadian clock in the suprachiasmatic nucleus (SCN). Photic information is transmitted to the SCN directly from the retina via the retinohypothalamic tract (RHT) and indirectly from the retinorecipient intergeniculate leaflet (IGL) via the geniculohypothalamic tract (GHT). The RHT is thought to be both necessary and sufficient for photic entrainment to standard laboratory light/dark cycles. An obligatory role for the IGL-GHT in photic entrainment has not been demonstrated. Here we show that the IGL is necessary for entrainment of circadian rhythms to a skeleton photoperiod (SPP), an ecologically relevant lighting schedule congruous with light sampling behavior in nocturnal rodents. Rats with bilateral electrolytic IGL lesions entrained normally to lighting cycles consisting of 12 hr of light followed by 12 hr of darkness, but exhibited free-running rhythms when housed under an SPP consisting of two 1 hr light pulses given at times corresponding to dusk and dawn. Despite IGL lesions and other damage to the visual system, the SCN displayed normal sensitivity to the entraining light, as assessed by light-induced Fos immunoreactivity. In addition, all IGL-lesioned, free-running rats showed masking of the body temperature rhythm during the SPP light pulses. These results show that the integrity of the IGL is necessary for entrainment of circadian rhythms to a lighting schedule like that experienced by nocturnal rodents in the natural environment.

Animals↗