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1,566 records · Page 87Linked to original sources
PubMed1976

[Significance of antibody titers in recurrent urinary tract infection in children (author's transl)].

2254 antibody titers have been measured by the indirect hemagglutination method in 84 children with recurrent urinary tract infection using single organisms as homologous or several strains from one species (E. coli, Proteus, Klebsiella, Pseudomonas) as polyvalent antigens. Increase of homologous antibody titers within 3 weeks following a significant bacteriuria (65% of all cases) has been found to be a more reliable parameter for diagnosis of infection than leukocyturia or clinical symptoms. Determination of antibody titers is a special diagnostic clue for differentiation of contamination of midstream urine and bacteriuria with less than 10(5) organisms/ml. Cross reactivity between a polyvalent E. coli antigen and homologous E. coli antigens was found in 85% of cases. High or low antibody titer levels do not allow to differentiate between upper or lower urinary tract infection nor are antibody titer levels indicative for kidney involvement and prognosis of the disease.

Antibodies, Bacterial↗
PubMed1993

[Clinical long-term studies of the treatment of chronic complicated urinary tract infections. Utility and recurrence after 14-day treatment by cefditoren pivoxil].

In this study, cefditoren pivoxil (ME 1207, CDTR-PI), a new oral cephem antibiotic, was given to 72 patients with non-catheterized complicated urinary tract infections (UTI) to evaluate clinical efficacy and safety, and also to investigate the rate of recurrence after completion of treatment. Daily dose of CDTR-PI was 100 mg t.i.d., and CDTR-PI was administered for 14 days. According to the criteria proposed by the Japanese UTI Committee, clinical efficacy of CDTR-PI was evaluated at day 7 and day 14. The rate of recurrence was assessed by bacterial count in urine as the marker. The following results were obtained. 1. Overall clinical efficacy rates were 68.4% on day 7 and 81.6% on day 14. The efficacy rate at day 14 was higher than the rate at day 7. 2. Bacteriologically, eradication rates were 75.5% at day 7 and 79.6% at day 14. 3. As to side effects, abdominal discomfort was observed in 1 case and its incidence was 1.6%. Incidence of abnormalities of laboratory findings was 10.4%, and these abnormalities were slight and transient. 4. Thirty-one patients were assessable to the recurrence of infections, 60% of them were judged as "cured" at 1-2 weeks and 3-7 weeks after completion of treatment. In this study, "relapsed", reappearance of causative organisms, was observed much more frequently than "reinfection". These results suggest that sufficient clinical efficacy and safety of CDTR-PI in non-catheterized complicated UTI were effected by 14 days treatment.

Administration, Oral↗
PubMed1977

Pelviureteric obstruction in childhood.

Pelviureteric junction obstruction is a common cause of intra-abdominal mass in childhood. The diagnosis is usually apparent when the characteristic signs of obstruction are seen at intravenous urography. A voiding cystourethrogram should be performed to exclude vesicoureteral reflux as the underlying condition. Obstruction may be further assessed by a diuretic load or by pressure-flow studies.

Adolescent↗
PubMed1977

Keys to the diagnosis of occult urologic disease in children.

All physicians who care for children should be aware of the many indications for further urologic examination. A straightforward algorithmic approach to urologic diagnosis is not possible. The physician must individualize and carefully weight the indications for the often-times expensive and uncomfortable tests that are required for urologic diagnosis. The reward is ample when a significant correctable lesion is recognized early enough for salvage on the basis of seemingly unrelated signs or symptoms.

Age Factors↗