Comment on the paper: enhanced deposition of radon daughter nuclei in the vicinity of power frequency electromagnetic fields.
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BACKGROUND: This study was conducted to investigate the effects of continuous microwaves (2.45 GHz) of different field intensity on acetylcholinesterase activity and protein conformation in muscle fractions from frog skeletal muscles. MATERIALS/METHODS: [corrected] Acetylcholinesterase activity in samples from muscle homogenate fractions exposed for 30 min to microwaves of low (10 mW/cm2) or high (20 mW/cm2) intensity at almost constant temperature (1.8 degrees - 2.0 degrees C) was measured by spectrophotometry for three consecutive days after irradiation and compared with the activity in a sham-exposed fraction. Infrared spectroscopy (between 1400 cm(-1)-1800 cm(-1) was performed on the lyophilised fractions using Bruker IFS 113 v. RESULTS: A significant decrease in enzyme activity on the day of exposure (by 8.4% and 13.6% at high and low field intensity, respectively) was observed. Forty-eight hours later the decrease in enzyme activity in samples exposed to both high- and low-intensity microwaves was less than that in sham-exposed samples. Infrared spectroscopy data showed the Amide I band to be negligibly affected and the absorption maximum in the Amide II band to be significantly shifted from 1540 cm-' (shamexposed) to 1559 cm(1) (exposed) after irradiation. CONCLUSIONS: Exposure to microwaves results in non-thermal, intensity-dependent, prolonged modification of acetylcholinesterase activity in frog skeletal muscles traced up to 48 hrs after exposure. Infrared spectroscopy data argue for induced conformational changes in the secondary structure of muscle proteins: increased content of beta-structures, random coils, and amorphous structures, which were more expressed at low field intensity.
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With advances in computer performance, the use of high-resolution voxel models of the entire human body has become more frequent in numerical dosimetries of electromagnetic waves. Using magnetic resonance imaging, we have developed realistic high-resolution whole-body voxel models for Japanese adult males and females of average height and weight. The developed models consist of cubic voxels of 2 mm on each side; the models are segmented into 51 anatomic regions. The adult female model is the first of its kind in the world and both are the first Asian voxel models (representing average Japanese) that enable numerical evaluation of electromagnetic dosimetry at high frequencies of up to 3 GHz. In this paper, we will also describe the basic SAR characteristics of the developed models for the VHF/UHF bands, calculated using the finite-difference time-domain method.
A variety and rate of non-cancer diseases occurred in humans as a result of chronic exposure to ionizing radiation or to electromagnetic radiation (EMR) of high and superhigh frequency have been compared. The intensity of EMR was slightly higher than a sanitary standard for population. A risk of health impairments in workers having occupational exposure to EMR was assessed on the basis of Selie's concept of development of non-specific reaction of the body to chronic stress factors (general adaptation syndrome), models of changes in the body compensatory reserves and calculations of radiation risk after severe and chronic exposure to ionizing radiation.