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Management of retinal detachment associated with choroidal coloboma using perfluoroperhydrophenanthrene (Vitreon).

Vitreous surgery using an internal tamponading agent and chorioretinal adhesion is commonly used to repair retinal detachment associated with choroidal coloboma. The detachment may, however, recur if fluid continues to leak through a retinal defect in the area of the coloboma, despite internal tamponade. We present a case in which a recurrent retinal detachment associated with coloboma following vitreous surgery with SF6 was successfully repaired in outpatient surgery using perfluoroperhydrophenanthrene (Vitreon) and endolaser photocoagulation.

Aged↗

Laser and proton radiation to reduce uveal melanoma-associated exudative retinal detachments.

PURPOSE: To assess whether laser-induced hyperthermia with proton irradiation of choroidal melanoma may decrease exudative retinal detachments more rapidly. DESIGN: Case control study. METHODS: Patients treated with laser-induced hyperthermia and proton radiation; results were compared with similar patients treated with only protons. RESULTS: All 11 patients treated with combined laser and proton therapy had resorption of subretinal fluid with a mean duration of retinal detachment of 193 days compared with 263 days in the group treated with only proton therapy (P <.04). At 1 year, visual acuity was similar. CONCLUSIONS: Combined laser radiation more rapidly dissipates exudative detachments than radiation alone.

Case-Control Studies↗

[Evaluation of surgical methods in the treatment of retinal detachment during the years 1979-1987].

The authors present the results of treatment by conventional methods of patients with retinal detachment in the period of 9 years. Reattachment of the retina was achieved in 78.3% of cases. The use of indirect funduscopy with a binocular ophthalmoscope for an intraoperative localization of the retinal holes as well as for their control and the intensity of cryopexy became a factor which increases the efficacy of the surgical treatment of retinal detachment.

Adult↗

Retinal detachment following cataract extraction by phacoemulsification.

A review of 1,107 cases of cataract extraction by phacoemulsification is presented. The incidence of retinal detachment in this group was found to be 1,7%. This incidence of retinal detachment following phacoemulsification appears to be favorable compared to that following conventional cataract extraction. It is hoped that this report will encourage others to study this important subject.

Cataract Extraction↗

[Retinal detachment in preeclampsia and HELLP Syndrome].

CASE REPORT: We report the case of a 33-year-old pregnant female with severe preeclampsia who developed serous retinal detachments and HELLP syndrome. DISCUSSION: Following delivery by Caesarian section, there was spontaneous resolution of the serous retinal detachments, with residual pigmentary changes of the retinal pigment epithelium. The patient recovered normal vision (Arch Soc Esp Oftalmol 2003; 78: 335-338).

Adult↗

An alternative method of gas-fluid exchange through the limbus in giant tears and other complicated retinal detachments.

An alternative method of gas-fluid exchange through the limbus in patients with giant tears and complicated retinal detachments is presented. The indications for the combined surgery of scleral buckle, vitrectomy, and gas-fluid exchange are suggested. The results of this type of surgery in 5 patients with giatn retinal tears, and in 12 patients with complicated retinal detachments, are reported. Most failures were caused by massive periretinal proliferation.

Air↗

Clinical trail of intravitreal C F in retinal detachment surgery.

A mixture of 40% octafluorocyclobutane (C4F8) and 60% air was used clinically in eight patients with long-standing retinal detachment. In seven cases the retina reattached after intravitreal injection of C4F8 and intrascleral diathermization of the retinal tear. The one failure was due to massive vitreous retraction and preretinal proliferation prior to the surgery. Except for a slight postoperative iritis when 4 cc of gas lasted for 12 to 30 days after intravitreal injection. On the basis of this and our previous studies, we recommend the use of C4F8 in retinal detachment surgery.

Adult↗

Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment (SPR Study): design issues and implications. SPR Study report no. 1.

BACKGROUND: In patients with more complex rhegmatogenous retinal detachments (RRD) not complicated by proliferative vitreoretinopathy (PVR), the most appropriate operating method is controversial, and different surgeons use different techniques. The Scleral Buckling Versus Primary Vitrectomy in Rhegmatogenous Retinal Detachments Study (SPR Study) is designed to compare primary vitrectomy and scleral buckling techniques in these patients. METHODS: The SPR Study is a multicentre, randomised, controlled clinical trial stratified by lens status. Patients with RRD which is not complicated by PVR grade B or C and which cannot be treated with a single meridional sponge are randomised to either scleral buckling or pars plana vitrectomy as first surgical intervention. Four hundred consecutive patients are to be recruited per subtrial (phakic and aphakic/pseudophakic patients), and followed up for 1 year. The primary endpoint (functional outcome) is the change in visual acuity. Secondary endpoints (anatomical outcome) include postoperative PVR, retinal reattachment and the number of reoperations necessary to achieve retinal reattachment. Twenty-seven institutions (49 surgeons) in six European countries have been recruited for participation in the study. CONCLUSION: The SPR Study is the first randomised prospective clinical trial to compare scleral buckling and primary vitrectomy in patients with RRD. The results of this study should enable vitreoretinal surgeons to improve the surgical therapy of patients with the more complicated manifestations of RRD.

Humans↗

[Intraoperative diagnosis of retinal ruptures in rhegmatogenous retinal detachment in avitreous eyes by using a coloring agent].

Sixteen patients were operated for regmatogene retinal detachment developed at different time periods after a previously made vitrectomy; no retinal ruptures were found in preoperative examinations. The method of colouring with subretinal fluid, 0.1% fluorescence solution, was intraoperatively used for the detection of such ruptures. The coloured fluid escaped from the subretinal cavity through a retinal rapture into the vitreal cavity, which ensured an easy visualization of ruptures. Retinal ruptures could be detected in all 16 (100%) patients. They were located in 8 (50%) cases in the zone of previously made sclerotomy and were regarded as an outcome of the local proliferative vitreoretinopathy on the remains of the basic vitreous elements.

Female↗

[Treatment of retinal detachment with a giant tear--personal observations concerning use of perfluorocarbon liquid].

The authors present results of the treatment of retinal detachment with giant tear in 12 eyes in 11 patients. The encirclement of the eyeball, vitrectomy and endo-tamponade with gas in 3 cases and silicone oil in 9 were applied. In 4 cases, perfluorocarbon liquid was used to unroll the retina. After 6-15 months follow-up retina was completely attached in 8 eyes (66%); in 3 eyes (25%) residual detachment was observed in the inferior part of the fundus and in 1 eye retina remained detached. In 8 eyes, visual acuity was above 5/50, in 3 above 1/50. The type of endo-tamponade and the role of perfluorocarbon liquid in this kind of retinal detachment are discussed.

Adult↗

Intraocular silicone oil for retinal detachment in AIDS: CT and MR appearances.

AIM: To describe the CT and MR features of intraocular silicone oil which is used to treat complex retinal detachments in patients with acquired immune deficiency syndrome (AIDS). PATIENTS AND METHODS: Seven male patients with AIDS were treated by pars plana vitrectomy and intraocular silicone oil injection for complex retinal detachments due to biopsy proven cytomegalovirus retinitis. Two patients had bilateral therapy. RESULTS: Silicone oil was hyperdense to muscle on CT with attenuation values of 106-139 HU (mean 115, SD 4.5). On MR, when compared with normal vitreous, intraocular silicone oil appeared hyperintense on T1-, proton density, and T2-weighted spin-echo sequences. A chemical shift artifact was seen on all MR images, being most marked on the T2-weighted images. CONCLUSION: The high attenuation value of silicone oil on CT and its hyperintensity on T1 weighted MR images my cause diagnostic confusion with haemorrhage. These entities can be distinguished at CT by directly measuring the attenuation number (silicone oil > 100 HU; blood < 90 HU), and at MR by the presence of a chemical shift artifact.

Acquired Immunodeficiency Syndrome↗

Low dose ocular irradiation for diffuse choroidal hemangiomas associated with bullous nonrhegmatogenous retinal detachment.

The authors describe five eyes in four patients with diffuse choroidal hemangiomas associated with progressive serous nonrhegmatogenous retinal detachment that were treated with low dose external beam ocular irradiation (1,250 to 2,000 cGy in multiple fractions). The subretinal fluid reabsorbed completely within 3 to 12 months of treatment in every case and there has been no reaccumulation in any case to date (median follow-up 14 months). Two of the patients have developed a focal posterior subcapsular radiation cataract in the treated eye (at 19 months and 66 months, respectively, after irradiation), but none of the patients has thus far developed radiation retinopathy. The authors discuss the potential benefits and risks of this form of treatment for choroidal hemangiomas with bullous retinal detachment.

Adult↗

Retinal detachment following YAG laser capsulotomy.

A retrospective study of 12 patients with rhegmatogenous retinal detachment following YAG posterior capsulotomy is reported. Eleven out of these 12 were at increased risk of detachment. Three had lattice degeneration, three had previous detachment and five had axial myopia. Only 50% of the holes were typical "aphakic" post-oral breaks.

Adult↗

Incidence of cystoid macular edema after retinal detachment surgery and the use of topical indomethacin.

We conducted a prospective, double-masked, controlled study to determine the effects of indomethacin in preventing the development of cystoid macular edema after retinal detachment surgery. In addition to routine medication, topical indomethacin was applied to 63 eyes (52 with intact lenses and 11 aphakic) and a placebo was applied to 61 eyes (51 with intact lenses and ten aphakic) that underwent retinal detachment surgery. Indomethacin drops or placebo were instilled once an hour for five hours preoperatively and three times daily for four weeks postoperatively. Fluorescein angiography, done before surgery and four to six weeks after surgery to detect cystoid macular edema, showed that cystoid macular edema developed in 11 of 63 eyes (13%) in the indomethacin-treated group and in 20 of 61 eyes (33%) in the placebo group (P less than .01). Five of 28 eyes (18%) with cystoid macular edema in both groups and 38 of 96 eyes (40%) without cystoid macular edema in both groups had visual acuities of 20/40 or better (P less than .05).

Administration, Topical↗

Management of complex retinal detachments by vitrectomy and fluid/silicone exchange.

The combined procedure of pars plana vitrectomy and liquid silicone exchange has been developed for the management of complex retinal detachment. Complete re-attachment was achieved in 88 per cent of eyes with giant retinal breaks and visual improvement occurred in 71 per cent. Macular re-attachment was obtained in 68 per cent of eyes with massive periretinal proliferation (MPP) and visual improvement occurred in 53 per cent. In contrast, in thirteen cases of severe diabetic traction detachment, only four remained attached with visual improvement in one. In seven eyes with severe perforating trauma and retinal detachment, retinal re-attachment was achieved in four and visual improvement in three. We conclude that this technique is indicated in giant retinal breaks, is encouraging in MPP, has a very limited role in the management of diabetic traction detachment, and requires further evaluation in the management of traumatic detachment.

Diabetic Retinopathy↗

Limited retinal detachment. A retrospective analysis of treatment with transconjunctival retinocryopexy.

Two hundred forty-one eyes with a "limited retinal detachment" were treated between 1967 and 1983 by transconjunctival retinocryopexy without scleral buckling. Follow-up ranged from 6 months to 10 years (mean, of 34 months). Anatomic reattachment was accomplished with retinocryopexy alone in 95% (228 eyes) of cases. Thirteen eyes (5%) were anatomic failures, but 12 of these were subsequently reattached with additional surgery. Risk factors for anatomic failure included multiple breaks, vitreous hemorrhage, and breaks with a rolled posterior edge. Visual results indicated that 229 eyes (95%) had stable or improved vision, while 12 eyes (5%) lost two or more Snellen lines. Causes for visual deterioration included premacular fibroplasia, proliferative vitreoretinopathy, and preexisting ocular pathology. Single breaks occurred in 172 eyes (71.4%), and multiple breaks in 69 eyes (28.6%). Associated clinical findings included high myopia (17%), surgical aphakia (12%), and retinal detachment in the fellow eye (27%).

Conjunctiva↗

How effective is macula-off retinal detachment surgery. Might good outcome be predicted?

PURPOSE: To determine factors associated with anatomical and functional outcomes of macula-off retinal detachment surgery in a modern vitreoretinal unit. METHODS: A retrospective casenote review of 185 patients presenting with macula-off retinal detachment was performed. Demographic and ocular characteristics were determined. Logistic regression analysis was used to determine (1) the effect of these factors on visual outcome and (2) their effect on primary and final anatomical success. RESULTS: Primary and ultimate anatomical success were achieved in 76 and 84% of cases. Patients with oil in at final follow-up were considered to be anatomical failures. Statistically significant factors predicting primary anatomical success using a multiple variable model were preoperative logMAR visual acuity, preoperative PVR and number of breaks. Preop logMAR visual acuity and duration of macular detachment were the statistically significant factors predicting ultimate success. In all, 44% of patients regained 6/12 Snellen or better with a median improvement of 0.78 logMAR. For prediction of visual outcome (in patients with no ocular comorbidity) only preoperative logMAR visual acuity achieved statistical significance (P=0.001) at the P=0.05 level. CONCLUSION: In all, 76% of macula-off detachments may be repaired with one operation and 44% of patients regain at least 6/12 Snellen. The median logMAR acuity increment of 0.78 far exceeds that seen in cataract surgery. Preoperative visual acuity is the most important factor predicting primary and final anatomical success as well as visual outcome. Preoperative PVR, number of breaks and duration of detachment also affect outcomes.

Adolescent↗