Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Reproductive disorders”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,549 records · Page 86Linked to original sources
PubMed1979

Hyperprolactinemia and polycystic ovarian syndrome.

Prolactin and pituitary gonadotropin levels were studied in eight patients with polycystic ovarian syndrome. All women were of reproductive age and had had menstrual disorders since menarche. Three patients had hyperprolactinemia with or without galactorrhea and tomograms of the sella turcica revealed pituitary microadenomas. The remaining five patients with normal baseline prolactin levels had a prolactin stimulation test which used 25 mg of thorazine per os, and a prolactin suppression test using l-dopa 500 mg per os. Analysis of the results of these tests and a comparison with tests performed in five normal individuals used as controls showed significantly different responses in the two groups of women. The preliminary information obtained indicates that an abnormal prolactin secretion status may exist in the polycystic ovarian syndrome.

Adolescent↗
PubMed1984

Adaptive and nonadaptive consequences of chemical inhibition of intercellular communication.

Intercellular communication is a fundamental process in multicellular organisms developed to orchestrate homeostatic control of mitotic and differentiation processes in pre- and postmitotic cells. Endogenous and exogenous chemicals can, via a series of mechanisms, interfere with intercellular communication between and within various tissues. The responses to the inhibition of non-gap-junctional and gap-junctional communication can be either adaptive or nonadaptive depending on the mitigating circumstances. The inhibition of gap-junctional communication appears to be one of the sequelae of a membrane-triggered response to many natural and man-made pharmacological chemicals. The biological consequences of inhibited intercellular communication might include teratogenesis (embryo or fetal toxicity), tumor promotion, reproductive toxicology, and neuroendocrine-related disorders.

Adaptation, Physiological↗
PubMedDate not supplied

[Effects of prenatal alcohol consumption upon fecundity, natality, growth, vaginal opening and sexual cycle in the rat (author's transl)].

The purpose of this study was to investigate the action of prenatal alcohol consumption upon offspring and sexual maturity parameters on a rat strain which, for several years, drank only a brandy/water solution. With regard to fecundity and number of pups our results show no variation, while weight, vaginal opening, and sexual cycle are severely affected by alcohol intake. Possible alterations upon offspring due to chronic prenatal alcohol intake are examined.

Animals↗
PubMed1994

Leiomyomatosis peritonealis disseminata. A report of two cases.

Leiomyomatosis peritonealis disseminata (LPD), also known as diffuse peritoneal leiomyomatosis, is characterized by the presence of multiple, small nodules scattered over the abdominopelvic viscera and peritoneum. These nodules are composed of benign smooth muscle cells. As shown in this report of two cases, the disorder occurs mostly in women of reproductive age and rarely in postmenopausal ones. LPD is a benign condition for which conservative management is indicated.

Adult↗
PubMed1994

The legal implications of abuse of the unborn foetus.

This article looks at the use of psychoactive drugs by pregnant women and the effects of these on the foetus. Firstly it discusses the historical awareness of alcohol related birth defects, and then the symptoms of foetal alcohol syndrome. There is also the condition known as foetal alcohol effects--a milder version of foetal alcohol syndrome--exhibited by children of alcohol abusing mothers. Secondly, various drugs, both legal and illegal, over the counter and prescription drugs, and their effects on the foetus are examined. Thirdly, the moral, ethical and legal problems facing the health care worker when dealing with a pregnant women who will not or cannot stop using a potentially harmful chemical, are probed in terms of the South African Child Care Act 74 of 1983. Finally a plea is made for more research in this area, and also that coercive treatment and commital procedures should only be applied when all other methods for treatment have failed.

Alcoholism↗
PubMed1993

Maternal-fetal health: ethical issues.

Modern medical technology has given us the ability to directly observe the fetus and its state of health. This ability has allowed the fetus to be newly individuated and has supported what often are called conflicts between the fetus and the pregnant woman. This article examines the nature of some of these conflicts and offers support for ethical theories and principles that assume that the pregnant woman is the appropriate decision maker for treatment involving her body and that if she is given support and comprehensible information, her decisions will be in the best interests of her family.

AIDS Serodiagnosis↗
PubMed1996

Toxicology testing in neonates. Is it ethical, and what does it mean?

A positive toxicology screen in a newborn may provide some explanation for signs and symptoms affecting the newborn's problems in the NICU. But, simply stated, it does not prove cause; it does not prove child neglect; it does not prove inadequate parenting capabilities. The evidence of maternal illicit substance use may provide us with information that a variety of risk factors associated with drug use may be interacting that could interfere with the infant's long-term well-being. The objective of screening must be focused on medical and health care issues, not on political or legal issues, and never intended for punitive actions toward the mother. Resources should be available to provide the mother with educational information, treatment programs, psychosocial counseling, and household support systems to assist her in her role as principal caregiver to her infant. Follow-up care for the baby should be provided by physicians and clinics familiar with high-risk infants and include ongoing neurodevelopmental surveillance in specialized programs if available.

Disclosure↗
PubMed1996

Women and migration: a public health issue.

The need to migrate is usually a function of the complex interaction of economic, social, familial and political factors. Among the most important, however, are the denial of access to education, employment, goods and services and the lack of respect for basic human rights. Because in many societies women are marginalized from these rights, migration to more economically and educationally open societies can often help improve their personal situation and their professional opportunities. On the other hand, because the status of women is usually linked to their role and status within the family and is defined in relationship to their male partners, migration can place women in situations where they experience stress and anxiety due to the loss of their traditional social entourage and environment. Their social integration in new settings may be equally limited by their initial lack of education and occupational experience. The higher vulnerability of women to sexual abuse and violence also places them at risk of STDs, including HIV, and a range of post-traumatic stress disorders associated with sexual violence. Their reproductive health needs often go unnoticed and unprotected even in well organized refugee and migrant situations, and the insensitivity of health staff to the needs of women is often more pronounced in refugee and migrant contexts than it is in general. Health monitoring of women in all migration-related situations has to be given greater priority. Similarly, much more attention at a health policy level is called for if the rights of women refugees and migrants are to be protected, and their contribution to health and social development is to be acknowledged and promoted.

Acculturation↗
PubMed1997

State and trait serotonergic abnormalities in women with dysphoric premenstrual syndromes.

Three to eight percent of women of reproductive age suffer from dysphoric premenstrual disorder (PMS). Although the exact pathophysiology of this disorder is not known, serotonergic dysregulation appears to be involved. In this article, we review and summarize the current data on changes in serotonergic parameters in women with dysphoric PMS and emphasize the distinction between state-related abnormalities which are present only during the symptomatic late-luteal phase and trait abnormalities which are present even during non-symptomatic phases of the menstrual cycle. The notion of diversified serotonergic systems that are selectively affected by fluctuations in gonadal hormones is discussed in the context of PMS as well as other dysphorias.

Female↗
PubMedDate not supplied

Punishing mothers.

Explore the source record for details and available documents.

Ethics, Medical↗
PubMed1998

The genetics of fibrodysplasia ossificans progressiva.

Fibrodysplasia ossificans progressiva is an autosomal dominant disorder. Most cases are due to new gene mutations because people with fibrodysplasia ossificans progressiva have markedly reduced reproductive fitness. The gene or genes responsible for this disorder are unknown.

Child↗