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PubMed1993

Scanning slit mammography.

The importance of scatter in mammography and the performance of conventional mammographic grids are reviewed. Without scatter control image contrast is significantly degraded. Conventional mammography grids improve the situation; however, their performance is limited. As a result for 5 to 8 cm thick breasts, a more ideal method of scatter control could result in a 25 to 45% improvement in contrast over that possible with conventional grids. One such approach is scanning slit mammography. The principles of this approach are presented along with the design and geometrical specifications of a prototype multiple scanning slit unit. The unit has a measured primary transmission of 91% and scatter transmission of 3%. Similarly measured performance values for a commonly used grid are 62% and 19%, respectively. Compared are images of a 6 cm breast phantom obtained with the scanning slit unit and a conventional grid. The scanning slit unit achieved noticeably greater image contrast with 30% less radiation. Also discussed are the limitations and engineering challenges of the technology.

Image Processing, Computer-Assisted↗
PubMedDate not supplied

Mammography and Pap smear screening of Yaqui Indian women.

The Pascua-Yaqui Tribe of Arizona receives its health care services at a local neighborhood health center in Tucson and a satellite clinic located on the reservation. Using a computerized data base from the health center, the authors determined the use rates by Pascua-Yaqui women ages 35-65 of the Papanicolaou smear and mammography screening. Among active users of the health center, 31-36 percent had received a Papanicolaou smear, according to the yearly data bases examined from 1986 to 1990, while 65 percent of the women had received at least one smear test over the entire 5-year period. Regarding mammography screening, 41-43 percent of the women ages 50-65 had received a mammogram in the years studied, and 51-58 percent of the women ages 40-49 had been screened. In all, 67 percent had received at least one mammogram during the 1988-90 period when the center offered mammography. This population of 35-65-year-old American Indian women, for whom financial access is not a barrier, were receiving Papanicolaou smears and mammograms at rates comparable with other segments of the U.S. population but at lower rates than those recommended by the American Cancer Society and National Cancer Institute. The challenge for the health center is to reach those women who are eligible for services but do not use them and to address the nonfinancial barriers to care such as language, transportation, and gender-specific issues.

Adult↗
PubMed1993

Mammography in women > or = 50 years of age. Predisposing and enabling characteristics.

The purpose of this study was to identify the relationship of selected predisposing and enabling characteristics of women > or = 50 years of age to mammography utilization. Andersen and Aday's theoretical model for health services utilization guided data collection. Data were collected from a convenience sample of 161 women members of four urban churches, using a mailed survey. Results showed that 81% reported at least one mammogram and 24% had followed mammography guidelines for the preceding 3 years. Results of logistic regression analyses with variables having a bivariate significance of p < or = 0.01 showed that higher income was associated with both ever having a mammogram and adherence. Willingness to pay > $50 out of pocket for a mammogram was significant for 3 year adherence. Additionally, the sociodemographic variables of age and religion were associated with adherence, whereas a college education was highly significant (odds ratio = 13.78) for ever having a mammogram. Having a regular place for health care and having yearly Papanicolaou tests were associated with ever having a mammogram, but not adherence. Finally, intending to get a mammogram was associated with ever having a mammogram. In this study, belief and knowledge variables showed no association with utilization, and social influence had bivariate significance only for ever having a mammogram. This study suggests the importance of addressing economic and health-care delivery system factors to promote increased mammography utilization, particularly for older women.

Aged↗
PubMed1993

Recruiting older women for screening mammography.

We compared health behavior and attitudes of older and younger women toward breast cancer screening by using data from the 1987 Texas Breast Screening Project, a community-based, low-cost screening program sponsored by the American Cancer Society, Texas Division. Because age is an important risk factor for breast cancer, the women were categorized into three age groups: 55 to 64 years old, 65 to 74 years old, and 75 years and older. Approximately 67% of the women 75 years and older, 64% of women in the 65 to 74 age group, and 59% of the younger (55 to 64) women had never had mammography. Moreover, only 14% of the women in both the 65 to 74 and 75+ age groups and 19% of the younger women reported having two or more mammographic examinations. Fewer older women (65 to 74 and 75+ age groups) reported having recent clinical breast examination. There were no differences among the age groups in the factors that attracted the women to participate in this screening program; in the three age groups, the most influential factors to participate were media publicity and lower mammography costs. Women in all age groups reported a lack of physician referral and cost as reasons for not previously participating in mammography screening. This study shows that older women are underscreened. Educational programs about the benefits of early detection should target older women because they are at increased risk for breast cancer.

Age Factors↗
PubMed1993

[The technique and results of mammography].

In the field of mammography, technical progress has been achieved and successfully implemented in routine practice in the last few years. The diagnostic value of mammography has been re-assessed in numerous studies. Breast conserving therapy of breast carcinoma has posed new pre- and postoperative diagnostic tasks. The introduction of mammography into a future national breast cancer detection program will present a challenge for many mammographers in several aspects. Radio-epidemiological doubts about introduction of mammographic screening are in-substantial.

Breast Diseases↗
PubMed1993

[Localization of non-palpable lesions by mammography for preoperative marking and tissue removal].

Mammography screening can increase survival by 15-50%. Minute nonpalpable breast carcinomas can be detected and surgically removed using precise localization techniques. Various techniques are shown, including localization by means of grid mammography and conventional localization with several needles. Stereotactic localization is recommended if the focus cannot be detected by sonography--a procedure now almost always possible if mammography units have the necessary additional equipment. In future it will often become necessary, following a good response to pre-operative chemotherapy, for the tumor, which as a result has become nonpalpable, to be marked prior to surgery (e.g. remaining microcalcifications). This is essential if a representative area of tissue is to be made available for histological examination.

Breast Neoplasms↗
PubMed1977

[Suction-radiography in mammography (author's transl)].

The value of the suction apparatus used in over 500 examinations as a simple addition to mammography has been convincing in our hands. Suction of 30 mm Hg, produced with a test-rubber bulb, achieves distension or stretching of the mamma. This leads to changes of position, shape and density of normal and pathologic structures and gives further information, compared with routine mammography. It is often possible to distinguish between spaces filled with fluid (cysts, hematomata) and solid tumours, pseudotumours and genuine growths, and between benign and malignant tumours. One essential indication is the "small" breast of various types (constitutional, post-operative and in men), because often suction will enable us to do a mammography. Suction radiographs are added in every 10th patient to previously taken compression radiographs with, of course, large and coned radiographs, which will yield a safe diagnosis in one half of the cases or confirm suspected findings.

Breast Diseases↗
PubMed1996

Benefits versus risks from mammography: a critical reassessment.

BACKGROUND: The use of mammography has increased rapidly over the last decade. The justification for mammographic examinations is the potential benefit they provide in detecting breast cancer at an early stage and reducing mortality. However, this benefit must be balanced against the associated potential risk of radiation carcinogenesis, economic costs, and a number of other factors. Most publications to date have used radiation risk factors and data from studies that were published over a decade ago, which now have been superseded by the results of more recent epidemiological studies. METHODS: This report examines the current literature regarding the benefits of cancer detection and the risk of radiation carcinogenesis, and calculates the ratio of benefit and risk for women who begin annual mammography screening at different ages. We have used current data to calculate the expected individual benefits and radiation risks associated with annual mammographic screening. RESULTS: It now appears that there is little risk of breast cancer associated with radiation exposure from annual mammography in women over the age of 35, although there is some indication that exposure of younger women may pose a risk for those women in a genetically sensitive subgroup. CONCLUSIONS: New data document that for a woman beginning annual mammographic screening at age 50 and continuing until age 75, the benefit exceeds the radiation risk by a factor of almost 100. Even for a woman who begins annual screening at age 35 and continues until age 75, the benefit of reduced mortality is projected to exceed the radiation risk by factor of more than 25.

Adult↗
PubMed1996

[MR-mammography: current status and perspectives].

Dynamic MR imaging of the breast is viewed as an examination technique which is supplementary to mammography and sonography and which can provide important additional diagnostic information. Proven indications for MR mammography include examinations of patients who have undergone lumpectomy and patients with prosthetic breast implants. The method also appears to be useful to differentiate between postoperative scarring and carcinoma as well as to exclude a multicentric breast carcinoma prior to lumpectomy. The sensitivity of MR mammography, however, is limited in cases of DCIS. Hypervascular benign lesions can be difficult to distinguish from malignant lesions.

Breast↗
PubMed1996

Combined fine-needle aspiration, physical examination and mammography in the diagnosis of palpable breast masses: their relation to outcome for women with primary breast cancer.

OBJECTIVE: To examine the combined and individual predictive values of fine-needle aspiration (FNA), physical examination (PE) of the breast and mammography (the "triple test") in diagnosing breast cancer in relation to the results of open surgical biopsy. DESIGN: A study of the records of patients who received both FNA and open surgical biopsy for the same palpable breast lump. The results of diagnostic assessment and open surgical biopsy were categorized as positive or negative. Concordance (percentage of tests found to be correct at biopsy), sensitivity, specificity (percentage of patients without breast cancer for whom the diagnostic test was negative) and positive predictive value (percentage of patients with a positive test found to have breast cancer) were determined for the triple test for each diagnostic modality. In addition, prognostic variables (tumour size, node positivity, estrogen and progesterone receptor status) and outcomes were assessed in patients with a diagnosis of breast cancer. SETTING: A university-affiliated general hospital with a special focus on women's health. PATIENTS: Of 290 patients who had both FNA and open surgical biopsy, 191 underwent all three diagnostic procedures. MAIN OUTCOME MEASURES: The diagnostic accuracy of FNA, PE and mammography to permit preoperative definitive therapy or to allow observation without mandating open surgical biopsy. RESULTS: In 81 patients all three diagnostic modalities were in agreement for a diagnosis of either benign or malignant disease; the concordance for the triple test was 98.8% specificity was 100% and sensitivity was 95.5%. Nodal status, tumour size and outcome were similar whether or not the triple test was positive, but, interestingly, when the triple-test results were positive, estrogen (p < 0.05) and progesterone (p < 0.03) receptor values were more likely to be negative. CONCLUSIONS: When all three diagnostic modalities were in agreement for a diagnosis of malignant disease, the combination of FNA, PE and mammography had excellent concordance with the results of open surgical biopsy, and in this situation definitive treatment may be carried out. If all three modalities are in agreement for a diagnosis of benign disease, a period of close observation with repetition of FNA may be safely entertained. Lack of concordance of the three diagnostic modalities mandates biopsy. Triple-test positively does not predict a worse outcome.

Adult↗
PubMed1996

Impact of a mailed intervention on annual mammography and physician breast examinations among women at high risk of breast cancer.

Only a few studies have examined repeat annual mammography rates, and most studies find that such regularity is low, ranging from < 5% in the general population to between 14 and 20% of first-degree relatives. The present study tested the effectiveness of a mailed intervention designed to improve compliance with breast cancer screening guidelines among women at elevated familial risk. The study used a pretest-posttest control group design; 369 twin sisters of breast cancer cases were assigned alternately to an intervention or a control group on the basis of sequential registration numbers. The intervention consisted of written materials, an audiotape, and mailed reminders. The posttest was mailed 2.5 years after the intervention in order to provide adequate time to assess the regularity of screening. The intervention and control groups were virtually identical with respect to demographic and baseline screening characteristics. Of those who returned the follow-up questionnaire, annual physician breast examinations were 12.8% higher and annual mammograms were 10.3% higher in the intervention group than in the control group. The probability of annual screening with physician breast examination and mammography was higher in the intervention group, and the probability of annual mammography continued to be higher for women over age 52 years after controlling for baseline screening, year of diagnosis, education, and status of the twin. This result is consistent with improvements found in other studies. Women who did not return follow-up questionnaires were more likely to have had fewer physician breast examinations and mammograms and more likely to be in the intervention group than those who stayed in the study. Additionally, those who dropped out of the intervention arm perceived themselves to be less susceptible and perceived screening to be less effective than did those who dropped out of the control arm. Although the intervention caused many women to be screened more regularly, those who had not been screened in the past and those who held opinions that were not conducive to screening were more likely to drop out. This mailed intervention for high-risk women increased their rate of screening. Characteristics of women resistant to such programs have been identified; alternative strategies need to be developed to reach this small percentage of high-risk women who ignore their elevated susceptibility.

Adult↗
PubMedDate not supplied

Compliance with the screening mammography program of British Columbia: will she return?

OBJECTIVE: To identify factors associated with compliance in the Screening Mammography Program of British Columbia (SMPBC). METHOD: Factors associated with rescreening within 18 months (annual compliers) and between 18 to 36 months later (late compliers) were identified in a cohort of SMPBC screenees using a self-administered questionnaire. RESULTS: Fewer than half of women initially screened within the SMPBC were annual compliers, nearly 40% not returning by 3 years. In women age 50+ years, annual compliers tended to have no prior mammography, no prior breast pain, a physician referral to SMPBC, and a normal initial SMPBC mammogram. Late compliers also tended to have no prior mammography, a physician referral, and a normal initial SMPBC mammogram. CONCLUSIONS: Several modifiable factors associated with compliance were identified: a physician referral to the program and possibly subsequent referral back to the program after workup for an abnormal mammogram.

Adult↗
PubMed1977

[Efficiency and practicability of the oblique mediolateral view as one-view mammography (author's transl)].

With one-view mammography the detection rate for carcinoma would seem to drop considerably, in the screening situation for early carcinoma (T0 and T1) down to 50 to 60% under unfavourable conditions. The precentage of mammographic findings not completely cleared up by one-view mammography amounts to 54% among our patients. One-view mammography therefore seems to be justified neither as screening nor as routine procedure.

Breast Neoplasms↗
PubMed1996

Should we recommend screening mammography for women aged 40 to 49?

In clinical trials, screening mammography has been shown to reduce mortality from breast cancer by about 25% to 30% among women aged 50 years and older after only 5 to 6 years from the initiation of screening. Among women 40 to 49 years old, the evidence supporting the efficacy of screening mammography is less convincing. Eight randomized controlled trials have reported no statistically significant reduction in breast cancer mortality among women age 40 to 49 years after 7 to 9 years from the initiation of screening. After 10 to 12 years from the initiation of screening, there is a trend toward a reduction in breast cancer mortality that appears to be smaller than that observed in women age 50 and older. Even if there is a small delayed reduction in breast cancer mortality among women age 40 to 49 years, the potential absolute benefit of screening women in this age group is likely to be small, given that the incidence of breast cancer is low. Since there is strong scientific evidence that mammography reduces breast cancer mortality among women age 50 and older, our national focus should be on screening these women who have the most to benefit.

Adult↗
PubMed1996

Relationships among objective and subjective risk for breast cancer and mammography stages of change.

This study examined the relationships among objective and subjective risk for breast cancer and mammography stages of change as defined by the Transtheoretical Model. Women who had higher objective risk of breast cancer, as defined by the Gail et al. algorithm (M. H. Gail et al., J. Natl. Cancer Inst., 81: 1879-1886, 1989), were more likely to perceive themselves at greater subjective risk for breast cancer. Among the components of objective risk, family history of breast cancer was the only significant predictor of subjective risk. Both objective and subjective risk individually predicted stages of change, such that higher objective and subjective risk were associated with an increased probability of being in a later stage of adopting mammography. However, when objective and subjective risk were included in a multivariate model, only subjective risk predicted stages of change. In additional multivariate analyses, subjective risk continued to predict mammography stages of change when "con" and "decisional balance" scores were included in separate models. These results suggest that future research may benefit from the explicit integration of personal risk perceptions with elements of the Transtheoretical Model to provide more powerful accounts of behavioral change processes.

Breast Neoplasms↗
PubMed1996

[Test for the assessment of the diagnostic accuracy of mammography. Results of 103 tests carried out by Italian radiologists].

This study reports the results of some voluntary Italian radiologists performing 103 proficiency tests in clinical (100 patients, 32 cancers) and screening mammography (150 patients, 17 cancers). Relative to the average accuracy of a panel of expert radiologists, 12 of 49 readers (27%) and 32 of 54 readers (56%) passed the clinical and screening mammography test, respectively. The results were significantly correlated with the readers' previous experience (years of mammographic practice [< 2, 2-4, > 4] and number of mammograms read [< 5,000, 5-10,000, > 10,000]). The rate of passed test was: < 2 years = 0%, 2-4 years = 40%, > 4 years = 66.6% (P = 0.002); < 5,000 mammograms read = 15.3%, 5-10,000 = 28.5%, > 10,000 = 69.2% (P = 0.02). The best results were achieved by the readers with a previous reading experience of at least 10,000 mammograms, a figure which might be used as the reference for a future criterion of accreditation on a national basis. Proper training before reporting mammography is fundamental to ensure a good diagnostic performance. The low number of tests performed in most Italian mammographic practice facilities makes local training highly questionable and requires quite a long time. Reference centers, adequately equipped for training, should be identified for this purpose. Proficiency tests such as those described in the present study are useful to assess individual performance and should be a part of a training program.

Breast Diseases↗
PubMed1997

Update in digital mammography.

Digital mammography is a rapidly developing technology that has great potential to improve upon and ultimately replace conventional film-screen mammography for the early detection of breast cancer. This article reviews current progress in digital mammographic systems, computer-aided diagnostic programs, and artificial neural networks. Digital mammographic systems are currently in an investigational phase only. Large-scale clinical trials are needed in all areas of digital mammography before this exciting new technology can be implemented outside of research centers.

Artificial Intelligence↗
PubMed1996

Trends in mammography and Pap smear utilization in Canada.

We have examined trends in the utilization of two preventive health procedures for women in Canada based on our analysis of the 1994 National Population Health Survey (NPHS) and comparisons with two previous large population health surveys. The NPHS provides evidence that Canadian women's use of mammography has continued to increase between 1990 and 1994, while use of Pap smears has remained steady. Increases in mammographic utilization are seen for all age groups and in all provinces of Canada. Women who are less than the recommended age of 50-69 years for screening mammography access these services in considerable numbers. Large proportions of women aged 18-24 and 65 or over have never had a Pap smear, and recency of Pap smear is associated with age. Income adequacy and educational attainment are still strong predictors of which women utilize Pap smears and mammograms. We conclude that the NPHS is sufficiently broad-based to be used in a surveillance program to track Pap smear and mammography utilization.

Adolescent↗