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Results for “LABYRINTH DISEASES”

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At least 1,549 records · Page 86Linked to original sources
PubMed1978

[Spontaneous and provoked nystagmus as a criterion of the duration of effect of hypnotics and narcotics in ambulant surgery (author's transl)].

A testing of usefulness of systematic search for spontaneous and provoked nystagmus relative to the duration of effect of several hypnotics and narcotics showed in 83% positive vestibular findings in 150 non-selected, ear sound patients. Vestibular nystagmus was still detected 2 hour p.o. in 74%, 3 hours p.o. in 30% and 4 hours p.o. in 7% of cases. 78 times (52%) a convergent or divergent posture nystagmus was recorded and 47 times (31%) a vertical nystagmus. The subjective sensations of the test persons are out of proportion to the objective findings. The localisation of the pharmacotoxic lesion is discussed.

Adult↗
PubMed1978

Vestibular-optokinetic interactions in normal subjects and in patients with peripheral vestibular dysfunction.

The vestibulo-ocular reflex (VOR) during rotation, optokinetic nystagmus (OKN), and interactions between the vestibulo-ocular and optokinetic systems were studied quantitatively in 10 normal human subjects, 15 patients with unilateral horizontal semicircular canal paralysis (UP), and 11 patients with bilateral horizontal semicircular canal paralysis (BP). The OKN gain (eye velocity/drum velocity) was not significantly different between the normal subjects and the patient groups. During tests in which rotatory and visual stimuli were presented simultaneously, the contribution to the observed eye movements by the VOR was only one-fourth to one-third of its gain during rotation in the dark in the normal subjects and UP patients. These interactive tests did not differentiate UP patients from normal subjects but did separate BP patients from normal subjects.

Adult↗
PubMed1986

[Otoneurological and biochemical research on the drivers of motor vehicles].

The aim of the study is to follow up the changes in auditory and vestibular systems, common interactions between the sensory systems and the changes in some biochemical indices after vestibular loading in drivers. Several groups of drivers of heavy freight trucks were studied, aged from 25-60 and a length of service from 5 to 30 years, according to a standard programme for otoneurological examination and application of modern otoneurological methods. The biochemical investigations were performed to 32 healthy and 19 sick drivers with vestibular disorders, prior to and post vestibular provocation. The following biochemical indices were studied: serotonin, histamine, cholinesterase activity, glucose, GOT, GPT, alkaline phosphatase, calcium, potassium, sodium, chlorides, inorganic phosphorus. The biochemical changes, associated with vestibular loading of organism were established not to be strongly manifested and coming out of the frames of the normal values, nevertheless, they are significant for a given subject and should not be neglected. The data are of importance in the vocational selection of driver-applicants, prophylaxis and treatment of those working under stress situations and extreme impacts.

Adult↗
PubMedDate not supplied

[Receptor epithelium of the vestibular apparatus and cochlea in exposure to acceleration and noise].

The method for isolating and treating the vestibular and cochlear compartments of the inner ear was developed. Also, the procedure of histological treatment of temporal bones was modified. The pathogenesis of vestibulo-cochlear disorders due to acceleration and noise was investigated using histology, electron microscopy and histochemistry methods. It was found that exposure to acceleration of 10 Gx for 5 min and single and repeated (for 7 days) exposures to high-frequency noise of 100 dB produced histological changes and functional-morphological variations in all receptors located in the vestibular and cochlear compartments of the inner ear.

Acceleration↗
PubMed1987

Induction of experimental endolymphatic hydrops by immunologic techniques.

Immunologic techniques have been used by many investigators to produce experimental endolymphatic hydrops models. These techniques, however, have achieved little success in producing models simulating the idiopathic endolymphatic hydrops of Meniere's disease, in which no inflammatory changes occur in the perilymphatic spaces. In this study, the antigen horseradish peroxidase (HRP) was injected into the endolymphatic sacs of ninety guinea pigs that had been systematically sensitized to this antigen. Endolymphatic hydrops was induced in sixty-seven of the subjects, sixty-four of which showed no inflammatory changes in the perilymphatic spaces. The endolymphatic sacs of the affected guinea pigs were packed with soft granulation tissue induced by immunologic mechanisms; it is felt that the hydrops was caused by disturbances in endolymph absorption resulting from these tissue formations. Our results suggest that the introduction of antigens into the endolymphatic sac may prove useful in producing endolymphatic hydrops with characteristics similar to those occurring in Meniere's disease.

Animals↗