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PubMed1976

[Normal excretion of corticosteroid hormones in rat urine studied by a thin-layer chromatographic method].

The author examined the parameters of normal excretion of cortico steroid hormones and their metabolites in urine of rats (11 single fractions) by the method of a thin-layer chromatography. The data could be accepted as norms of corticosteroid excretion in urine of young adult rats of the strain Wistar. Nine biological important indices e-corticosteroids in urine of normal rats were described. He discussed the physiological pecofliarities of the normal excretion of corticosteroid hormones and genetical and/or nongenutical factors, determining corticosteroid formula in urine of the rat. He indicated the significance of a thin-layer chromatography for the determination of corticosteroid excretioi-for the evaluation of the functional state of the adrenal cortex and liver under various experimental conditions.

11-Hydroxycorticosteroids↗