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[Division of the pituitary stalk (mischotomy) for malignant exophthalmos after treatment of Basedow's disease with I 131].

The authors report a case of malignant exophthalmia occuring after treatment of Grave's disease with I 131. The exophthalmia was resistant to corticosteroids, thyroxin in large doses, reserpine, and the patient was treated by mischotomy (division of the pituitary stalk with interposition of polyethylene strips). There was progressive marked regression of the exophthalmia with return to work and normal social life.

Female↗

[Personal experience in the study of thyroid autoimmunity and endocrine exophthalmos].

Most of the thyroid disorders are considered as being autoimmune diseases. It is the case for autoimmune thyroiditis where various antibodies are found. In Graves' Basedow disease, one or several immunoglobulin(s) which stimulate(s) the thyroid were found. In simple goitre, autoimmune origin is probable. We have measured the presence of anti-alpha-galactosyl antibody in various thyroid disorders. An increase titre was observed in progressive Graves' ophthalmopathy, untreated Graves' disease, progressive simple goitres and in autoimmune thyroiditis. Therefore, we think that the measure of anti-alpha-galactosyl antibodies represents reproducible parameter in order to know if the thyroid disease is or not in progression.

Autoantibodies↗