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Results for “Tuberculosis, Lymph Node”

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PubMed1987

[Detection of pulmonary tuberculosis in adolescents in institutions of the general medical network and efficacy of its treatment].

Altogether 100 adolescents with TB detected on referral to general medical institutions were followed up. 30 patients with a clear-cut TB clinicoroentgenological pictures were referred to special hospitals. The rest 70 adolescents were followed up in general outpatients departments. The chief method of prehospital diagnosis verification was inefficacy of previous antiinflammatory therapy. 51 patients were not examined for tuberculosis (tuberculin test, chest x-ray, sputum investigation for tubercle bacilli, phthisiologist's consultation, etc.). Clinical evaluation showed that 47% had had previous contacts with tuberculosis patients, 33% demonstrated hyperergic sensitivity to tuberculin, in 21% the disease coincided with intensification of tuberculin reactions, 55% isolated tubercle bacilli. Initiated antituberculosis therapy alleviated the disease course in most of the patients. However, late diagnosis resulted in the formation of noticeable residual changes in a considerable proportion of patients. The results obtained indicate the necessity of close contacts between antituberculosis service and general health service to improve the effectiveness of adolescents therapy.

Adolescent↗
PubMed1988

Are tuberculous patients at a great risk from hypercalcemia?

The risk of tuberculous patients to develop hypercalcemia was investigated in 33 patients aged 19 to 80. Twenty-two of the 33 received no vitamin D supplements. Before antituberculous chemotherapy serum calcium corrected for albumin and urinary calcium levels were normal, serum 25-hydroxyvitamin D (25(OH)D) levels were low, but serum 1,25(OH)2D levels, oral calcium load test and intestinal 47Ca absorption were normal. After 17 to 34 days of chemotherapy serum calcium corrected for albumin and 1,25(OH)2D levels were lower without change in serum D-binding protein. In 11 patients 25(OH)D, 50 micrograms/day, was given orally for two months. 25(OH)D given three days before chemotherapy in five patients induced an increase of levels of 1,25(OH)2D which was greater than in 10 control patients with similar serum levels of 25(OH)D. When chemotherapy was added to 25(OH)D, the five patients showed high normal 1,25(OH)2D levels. The last six patients received 25(OH)D together with or after starting chemotherapy. None of the 33 patients developed hypercalcemia, even when supplemented with 25(OH)D for two months. It appears that hypercalcemia is uncommon in tuberculosis.

Adult↗
PubMed1988

Tuberculosis in five basset hounds.

Five Basset Hounds (2 females and 3 males) under the age of 5 years, acquired systemic tuberculosis. We suspected tuberculosis in one dog, because it had histologic lesions similar to those in 4 dogs in which bacteria were identified as Mycobacterium avium complex. A review of canine tuberculosis revealed a similar diagnosis in a Basset Hound. The association of this infection in Basset Hounds suggests an inherited immunologic defect. Results of our survey suggest that the defect might exist in cell-mediated immunity.

Animals↗