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Within-mouth correlations and reliabilities for probing depth and attachment level.

Replicate measurements of probing depth and attachment level were made by three examiners on the six Ramfjord teeth of 34 patients. Within-mouth correlations were high for single measurements, and yet higher for means across replicate measurements. Inter- and intra-examiner variability were both found to be low relative to between-patient variability. Conclusions are that the low within-mouth correlations reported by others may be the result of poor reliability, and that it is inappropriate to take the individual site as the unit of statistical analysis in clinical studies of periodontitis.

Adult↗

A new monitor with a zinc-oxide thin film semiconductor sensor for the measurement of volatile sulfur compounds in mouth air.

Halitosis, defined as unpleasant oral odor, is a concern among the general public. Halitosis is generally diagnosed by organoleptic examination and by gas chromatographic analysis of the main source of halitosis, volatile sulfur compounds, such as hydrogen sulfide, methyl mercaptan, and dimethyl sulfide. Gas chromatography requires a large-scale system and a long running time. We investigated the use of a zinc-oxide thin film semiconductor sensor for measuring trace volatile sulfur compounds in mouth air. Mouth air samples collected in teflon bags from 21 volunteers were analyzed by 3 methods: the monitor analysis, gas chromatography, and organoleptic examination by 3 judges. The readings of the monitor were correlated with the values of the total volatile sulfur compounds measured by gas chromatography (r = 0.75, P < 0.01) and also with the organoleptic scores given by the judges (r = 0.76, P < 0.01). The organoleptic scores were correlated with the gas chromatographic values (r = 0.71, P < 0.01). These results suggest that this new monitor with a zinc-oxide thin film semiconductor sensor may be used for the diagnosis of halitosis. Its small size and simplicity of handling may enable its use for routine chair-side study and field surveys of halitosis.

Breath Tests↗

Osteoma of the condyle as the cause of limited-mouth opening: a case report.

Osteoma is a benign tumour consisting of mature bone tissue. It is an uncommon lesion that occurs mainly in the bones of the craniofacial complex. Only a few cases involving the condylar process have been reported. An osteoma of the left condyle causing limited mouth-opening in a 32-year-old Malaysian Chinese female is reported here to alert the practitioner to consider this lesion as a diagnostic possibility in instances of trismus or limited-mouth opening.

Adult↗

The effect of oxidizing water on metallic restorations in the mouth: in vitro reduction behavior of oxidizing water.

Mouth-rinsing with oxydized water which contains electrolytically generated chlorine is known to hinder dental plaque formation and growth, but it also accelerates the deterioration of metallic restorations in the mouth. The present work consists of an in vitro study to elucidate the electrochemical reactions involved in the reduction of oxydized water on dental alloys through a systematic investigation of the potentiostatic polarization behavior of dental alloy electrodes. The five dental alloys selected for investigation were gold alloy, gold alloy containing platinum, silver-palladium-gold alloy, conventional amalgam and high copper amalgam. The corrosion potentials of all dental alloy electrodes were shown to be more noble in oxydized water than in 0.1N sodium chloride solution. The potential differences between the corrosion potentials were relatively small in the case of amalgam electrodes. The polarization curves for all of the dental alloy electrodes in oxydized water revealed reduction currents of chlorine, hypochlorous acid, dissolved oxygen and oxonium ion. The reduction of chlorine and hypochlorous acid started at a more noble potential than that of dissolved oxygen. The dental alloys studied, except the amalgams, did not dissolve excessively at the corrosion potentials in oxydized water.

Chlorine↗

Metal release from cobalt-chromium partial dentures in the mouth.

The amounts of cobalt and chromium released to the saliva in individuals wearing cobalt-chromium partial dentures have been measured. Saliva was collected during a 5-min period, both with and without dentures in the mouth, and the two samples compared. More than 80% of the 30 cases showed increased amounts of metals with the denture in the mouth. Newer and larger dentures liberated more than did older and smaller ones. The median increase in chromium was approximately twice that of cobalt.

Chromium↗

Omeprazole and dry mouth.

BACKGROUND: Omeprazole causes irreversible inhibition of the hydrogen/potassium adenosine triphosphatase enzyme, leading to a marked reduction in both acid secretion and volume of gastric juice. Reported side-effects include nausea, vomiting, diarrhoea, constipation, and headache. We report the development of dry mouth during omeprazole therapy. METHODS: We have identified six patients taking omeprazole for more than 6 weeks who complained of a dry mouth. Salivary production was measured as whole salivary flow produced over a 10-min period spat into a collecting vessel and as 5% citric acid-stimulated parotid salivary flow collected with a Lashley cup device placed over the parotid duct. Flow rates were evaluated both during and after cessation of treatment. Saliva produced was then cultured for microbes. RESULTS: Four of the six had subnormal parotid or whole salivary flow rates on treatment that recovered after stopping treatment. The increase after treatment was marked in four. Significant amounts of Candida albicans grew from the saliva of the three patients with the lowest salivary flows; one saliva also grew Staphylococcus aureus. CONCLUSION: Salivary flow is reduced in some patients treated with omeprazole, returning to normal after cessation of treatment. This reduction may predispose to opportunistic infection, particularly in the edentulous.

Aged↗

Salivary gland scintigraphy in subjects with and without symptoms of dry mouth and/or eyes, and in patients with primary Sjögren's syndrome.

The major salivary glands were examined with 99m-Tc-pertechnetate scintigraphy in randomly selected subjects with (n = 30) and without (n = 12) symptoms of dry mouth and/or eyes, and in patients with primary Sjögren's syndrome (1 degree SS, n = 17). The scans were quantitatively evaluated and compared to other objective tests used to diagnose 1 degree SS. As compared with those for asymptomatic subjects, most values for the scintigraphic variables were non-significantly lower for symptomatic subjects and the time-activity curves were slightly flatter for all major salivary glands. In patients with 1 degree SS most values for the scintigraphic variables were significantly lowered and the submandibular glands were the glands most affected, as reflected in a flat time-activity curve, while the parotid glands were mainly affected during stimulated secretion. The scintigraphic variables correlated with the self-rated dryness of mouth in symptomatic subjects and with the abnormality of sialometry results in patients with 1 degree SS. We conclude that salivary gland scintigraphy is a sensitive and valid method to measure salivary gland function and abnormalities.

Aged↗

The influence of concurrent load on mouthed and vocalized modality effects.

A visual search task was coupled with the serial recall of words to assess the extent to which modality effects mediated by vocalizing and silent mouthing reflect an automatically activated preattentive process. Overall, serial position functions systematically changed as concurrent task demands increased, but the magnitude of the modality effect associated with both mouthing and vocalizing was not altered, regardless of whether or not subjects simultaneously searched for digits. These results support the notion that modality effects index a preattentive process that can be activated automatically by either spoken input or gestural cues associated with speech.

Adult↗

[Sternocleidomastoid myocutaneous flap for reconstruction after resection of carcinoma in floor of mouth].

OBJECTIVE: To evaluate the clinic outcome and indications of sternocleidomastoid (SCM) myocutaneous flap for reconstruction after resection of carcinoma in floor of mouth. METHODS: Thirty-two patients underwent SCM myocutaneous flap for reconstruction of the floor of mouth were reviewed. According to the clinical data and the follow-up, the appearance and function were analyzed. RESULTS: Only one myocutaneous flap was partial necrosis in termination of the flap, and growth with granular. In eight cases, partial epidermal loss over the skin paddle occurred with secondary healing with mucosal epithelium. All patients had oral diet with good separation of the oral floor and the tongue, and had no difficulty in speech intelligibility. The patients' appearance, function and the overall quality of life were improved. CONCLUSION: The SCM myocutaneous flap appears to be easy to use and suitable for reconstruction of the defect after resection of oral floor carcinoma, the indications of this flap should be selected carefully.

Adult↗

What the mouth has to say about diabetes. Careful examinations can avert serious complications.

Periodontal disease is a major but preventable complication of diabetes mellitus. Patient education, good glycemic control, regular dental care, appropriate diet, and a team approach that involves physicians, dietitians, dentists, and other health professionals offer the best chance for optimum care for these patients. Other oral complications of diabetes include tooth decay, xerostomia, candidiasis, and oral peripheral neuropathy. The mouth may also reflect secondary causes of diabetes, and oral examination may provide clues to diseases that coexist with type 1 diabetes. Truly, the mouth has much to say about diabetes.

Diabetes Complications↗

Accidental coadministration of intravenous aminophylline and theophylline by mouth: a hazardous practice.

Eight patients who inadvertently received theophylline by mouth and aminophylline by the intravenous route together were reviewed by the Clinical Pharmacology Service of the Royal Adelaide Hospital because their serum theophylline levels were in excess of the stated therapeutic range. Six of these patients were severely compromised by their high theophylline level, and two of them, who had advanced obstructive lung disease and respiratory failure, died shortly after the drug levels were detected. Oversights of this nature can arise during the early stages of a patient's hospital admission and when medical staff changes occur. All patients who receive aminophylline by the intravenous route must be kept under close surveillance to ensure that theophylline formulations are not given by mouth concurrently.

Accidents↗

[A longitudinal study of hand-mouth contacts of pre-term infants].

The developmental change of spontaneous hand movements were investigated longitudinally in 5 low-risk pre-term infants. The observation period was divided into three: 33-40, 41-52 and 53-60 weeks in order of gestational age. Both hand-mouth contacts (H-M-C) and hand-face contacts (H-F-C) were frequent in the 33-40-week period, and decreased drastically in the 41-48 week period. In the 53-60-week period, the number of H-F-C remained at a low level, while H-M-C increased again to the level of the first period. Furthermore, the mouth was open as the hand came into contact with it as frequently in the 33-40-week period as in the 53-60-week period. These findings suggest that H-M-C are neurologically distinct from H-F-C, and that the H-M-C before 41 weeks and after 50 weeks share some common components of this neurological mechanism.

Child Development↗

Effect of a mouth rinse containing amyloglucosidase and glucose oxidase on recurrent aphthous ulcers in children and adolescents.

Recurrent aphthous ulcers are one of the most common painful diseases affecting the oral mucosa in children and adults. The aetiology is poorly understood and the treatment thus has for years mostly been symptomatic. However, there has been some promising methods in decreasing the frequency of aphthous ulcer episodes. One of these is the use of a dentifrice containing the combination of the enzymes amyloglucosidase and glucose oxidase (Zendium). The aim of this investigation was, in a pre-study and a double-blind, crossover study, to report if a mouth rinse containing the same enzymes was effective against aphthous ulcers. Thirty-six children and adolescents 7 to 19 years of age took part in the pre-study and thirty-three children and adolescents 7 to 19 years of age took part in the double-blind, crossover study. In both tests the mouth rinses with enzymes resulted in a significant reduction in the number of new aphthous ulcers and pain. In the double-blind, crossover test the 33 children experienced 60 episodes of new ulcers during a 6-month period, including a 3-month period with enzyme rinsings, compared to 221 episodes when rinsing with placebo solution. 55% of the children were completely free from ulcers during the enzyme solution rinsing period followed by a 3-month recovery period compared to 0% when rinsing with placebo. The study confirms earlier studies. Daily rinsing with the enzyme solution can be a recommended treatment to children and adolescents with recurrent aphthous ulcers.

Adolescent↗

Instrumental evaluation of mouth odor in a human clinical study.

Gas chromatography and a flame photometric detection system measured directly from mouth air the sulfur volatiles associated with malodor. Statistically significant reductions in the hydrogen sulfide and methyl mercaptan levels were observed with use of the test rinse vs a placebo rinse. The method appears potentially useful in objective clinical evaluation of mouth odor.

Adult↗

Treatment of orthodontic white spot lesions with a remineralizing dentifrice applied by toothbrushing or mouth trays.

This pilot study investigated the effect of a remineralizing fluoride dentifrice (Enamelon) on newly formed incipient carious lesions using two methods of application. Teenage orthodontic patients with obvious white spot lesions on their teeth were selected to begin treatment within 30 days after debanding. At baseline, the surface enamel of the test teeth was cleaned by air etching with 50 microns alumina at 150 psi. Lesion size (mm2) was measured using a calibrated periodontal probe and surface appearance was quantified as shiny (0), dull (1), or chalky (2). Twice daily for 3 months, one group with a total of 27 lesions brushed with the remineralizing dentifrice, while a second group with 41 total lesions brushed and used a mouth tray to apply the paste directly to the lesions for 5 min. In order to promote treatment compliance, test group assignment was based on subject and parental preference. After 1, 2, and 3 months, lesion size was reduced by 5% (ns), 10% (p < 0.05) and 22% (p < 0.01), respectively, for the brushing group, and 16% (p < 0.05), 37% (p < 0.01) and 30% (p < 0.01) for the combined brushing and tray group, respectively. The dull appearance of the lesions treated by brushing improved slightly over 3 months. However, the lesions receiving combined brushing and tray applications became significantly (p < 0.01) less dull by 28%, 44% and 61% after 1, 2, and 3 months, respectively, indicating the formation of a shiny, intact surface layer. In conclusion, brushing with a remineralizing dentifrice significantly reduced the size of new orthodontic white spots within 2 months, while brushing combined with topical tray applications reduced lesion size within 1 month with concomitant formation of a shiny enamel surface layer. Thus, the combined brushing and mouth tray treatment significantly accelerated the remineralization process.

Adolescent↗

The Xerostomia Inventory: a multi-item approach to measuring dry mouth.

OBJECTIVE: To develop a valid multi-item method of measuring the symptoms of xerostomia which includes the wide range of xerostomia symptoms in a single quantitative measure. DESIGN: A combination of qualitative and quantitative approaches. SETTING: A cohort study in South Australia. PARTICIPANTS: Older people aged 65 years or more who were taking part in the South Australian Dental Longitudinal Study. MEASURES: Xerostomia symptoms were evaluated using a multi-item inventory format and, for comparison purposes, a standard single dry-mouth question. Resting whole-salivary flow rate was estimated using the 'spit' method. RESULTS: Xerostomia and flow-rate data were available for 636 individuals. Factor analysis revealed the presence of a discrete xerostomia dimension, represented by 11 items whose responses were summated to give a single Xerostomia Inventory (XI) scale score. This had a very low correlation with resting flow rate but a much stronger, positive correlation with the standard dry-mouth question responses. CONCLUSIONS: The XI shows adequate content and concurrent validity, and appears to be a promising advance on previous approaches to xerostomia symptomatology although further testing is required.

Aged↗

Direct-indirect heat-cured occlusal splint fabrication for a patient with limited mouth opening.

There are several conditions that can cause limited mouth opening. Recent literature on some of the most common conditions is discussed in this article. The difficulty in making alginate impressions may prevent indirect laboratory fabrication of heat-cured occlusal splints for patients with limited mouth opening. This article presents a combined direct-indirect technique for fabricating a heat-cured laboratory-processed maxillary occlusal splint in a case where making a mandibular alginate impression would have been extremely difficult. An extra-hard baseplate wax interocclusal record was used as a template for occlusal splint fabrication. The wax record was fitted to the maxillary side, then the mandible was gently manipulated to provide light imprints of the opposing teeth. The wax record provided the therapeutic vertical dimension as well as the therapeutic interocclusal relationship for the occlusal splint. The wax record was seated and sealed to the maxillary cast and modified on the palatal and facial aspects for the appropriate splint shape. The splint was processed using clear heat-cured acrylic resin. It required minimum adjustment on delivery. This procedure spared the patient from having a lower impression, which would have been required for the traditional laboratory-made occlusal splint. Increased adjustment time and excessive exposure to unoccurred acrylic resin, which would have occurred with direct intraoral fabrication, were minimized or eliminated using this technique.

Acrylic Resins↗

A mouthful of trouble.

The prehospital providers in this case performed a thorough and detailed assessment. They searched for and found a puncture wound in the posterior buccal region, and learned the patients was also hypoglycemic, with a history of diabetes, and insulin-dependent. It was not clear how the patient arrived at a hypoglycemic state, or if he had suffered a seizure. After the family arrived at the hospital and went to the patient's home, they determined the circumstances that caused this unusual presentation: The patient was the victim of a home-invasion robbery and had been shot in the mouth with a small-caliber weapon. The home invasion had taken place approximately 12 hours prior to the victim being found. The victim had been knocked unconscious by the force of the shot, although the bullet did not break any bones. He had not eaten prior to the shooting. Upon arrival at the ED, a small exit wound was noted behind the patient's left ear--hair and dried blood had obscured it from the prehospital providers. However, the providers did alert the ED physician to the buccal puncture wound, which enabled the physician to consider the possibility that the mouth wound was the result of a gunshot. Gunshot wounds are unpredictable in their damage patterns and effects on their victims. They might lead a patient to become hemodynamically unstable, but that was not the case here. Hemodynamic stability should not preclude the consideration of traumatic insult throughout your assessment. The initial presentation of this patient may have tempted EMS to pursue the suspicions stated by the neighbor at the scene (seizure), but a detailed assessment provided the information necessary to treat the man appropriately.

Aged↗