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Diverticular disease: a retrospective study of surgical management 1970-1980.

At Concord Hospital during the period 1970-1980, there were 2,530 admissions for diverticular disease. One hundred and twenty nine patients required operative treatment, 80 patients had a 'planned' resection and of the 56 patients admitted with peritonitis, 49 came to operation. The hospital mortality following resection was 7.5% and following operation for peritonitis was 14%. The morbidity after planned resection was 36% and after operation for peritonitis was 51%. Measures adopted to improve these results are discussed.

Diverticulum, Colon↗

[Treatment of eventrations].

Under study were 113 cases of eventrations. The paper presents general principles of conservative and surgical treatment. In operations for complete and true eventrations transplants of dura mater were used in order to additionally strengthen the frontal abdominal wall and to delimit the abdominal cavity from the operation wound. Clinical tests of this method in the treatment of 31 patients have revealed its advantages (there were no recurrences of eventration and no intestinal fistulas).

Adult↗

[Reflections concerning the fixation of the small intestine or of mesentery in the adult (author's transl)].

On the basis of their own observations as well as those collected during a round table meeting of the Association Française de Chirurgie, the authors attempt to give an objective review of the value of these operations in relations to the technique used, the operative circumstances and the indications. A detailed analytical study shows that mortality and morbidity have a relatively low prevalence. Long term results are favourable in 73% of cases. The risk of recurrent obstruction is of 5 to 10%. Emphasising contraindications on a so-called "prophylactic basis" and in certain pathological states, the authors conclude that such procedures are valuable in recurrent obstructions and deperitonisations after extensive viscerolysis.

Humans↗

[Collection of digesta flowing into the large intestine after post-ileocolic valve fistulation: preliminary results].

The various techniques of ileocaecal reentrant fistulation now used to collect digesta flowing from the small into the large intestine, do not provide an accurate estimate of digestion in the small intestine. Their main disadvantages are: an erroneous description of the kinetics of food passage (collection proximal to the valve or bypass of the ileocaecal valve) and changes in the ileal microflora. A new surgical technique is described (fig. 1) for collecting the digesta as they have been propelled through the ileocaecal valve, thus maintaining the functional role of the valve. When using such a technique, the digesta collected into a rubber bag must be returned to the proximal colon by the investigator. Using this post-ileocolic valve fistulation technique, the disorders commonly reported with the other techniques are avoided, and a true picture of food passage at the ileocaecal valve is obtained.

Animals↗

[Wound-healing disorders and mortality in one- and multi-stage sigma and rectum resections].

From 1958 to 1978, the Surgical Clinic of the Tübingen University carried out 427 sigmoidal and rectal resections with a one-, two-, or three-stage proceeding. The comparison proves that, as was to be expected, the one-stage resection more often shows an anastomotic insufficiency. On the other hand, there occur less infections of the abdominal wall because of the absence of a smear-infection deriving from the temporary intestinal fistula. The primary lethality through anastomotical complications does not differ in the one-, two-, or three-stage proceeding if in the latter you effect an only mechanical cleaning of the inactive colon leg. The irrigation of the inactivated colon with an antibiotic solution before the tumor resection leads, compared to the cleaning with saline solution, to much less infections of the abdominal wall, less anastomotic insufficiencies and to the reduction of the primary lethality. This three-stage proceeding is, with a lethality of 1,5%, still the most secure action for the patient.

Anti-Bacterial Agents↗

Colonic inhibition of gastric acid secretion in the dog.

The colon has been shown to contain an abundance of endocrine cells. Their role is not yet understood. In four dogs prepared with chronic gastric fistula and colonic fistula in the cecum the effects on pentagastrin dose responses of colonic perfusion with the following substance were studied: saline, 15% liver extract pH 7.0; sodium oleate pH 9.4; and 0.08 M HCl. The responses obtained in each of the perfusion studies were compared with those obtained without colonic perfusion. Whereas saline had no effect on these responses, liver extract, sodium oleate, and HCl, each produced significant inhibition. These results suggest that the colon has the capacity for inhibiting gastric acid secretion by some mechanism which may prove to be humoral. Until now the colon has rarely been considered in any assessment of the gut functioning as an endocrine organ. Perhaps a colonic endocrine role should now be given further consideration.

Animals↗