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At least 1,513 records · Page 84Linked to original sources
PubMed1975

[Radiographic study of the hand in 50 cases of primary articular chondrocalcinosis. Comparison with a control series of 100 subjects].

The authors analysed radiograms of the hands of 50 patients suffering from primary articular chondrocalcinosis (ACC) and compared them with those of 100 control subjects of similar sex and age. There were 40 women and 10 men, with an average age of 69.6 years (plus or minus 9.82). A chalky incrustation of the semilunar pyramidal interspace was observed in 40 percent of cases. The frequency of this incrustation was next in order of importance to incrustation of the triangular ligament which occurred in 52 percent of cases. The difference from the controls was highly significant (p less than 0.001). Voluminous geodes affecting one or more of the bone of the wrist were present in 20 percent of the patients with ACC and in 5 percent of the controls. The difference was significant (p less than 0.01). Chalky deposits were found in the soft tissues immediately next to a metacarpo-phalangeal articulation in 22 percent of the ACC patients but not in any of the controls. The difference was highly significant (p less than 0.001). These chalky deposits next to metacarpo-phalangeal articulations were always associated with chalky incrustation of the radio-carpal joint. As regards the radiological lesions, considered as being typical images of arthrosis and affecting the trapezo-metacarpal, metacarpo-phalangeal, and interphalangeal articulations, the chondrocalcinosis patients appeared to be more frequently affected than the controls, but the difference was not significant. On the other hand, a type of arthropathy occurs in ACC patients which also resembles an arthrosis radiologically but which was 5 times more frequent in them than in the controls and which in this series occurred without nearby trapezo-metacarpal arthropathy only in ACC patients (16 percent as against 0 percent in the controls: p less than 0.001); this was scapho-trapezial arthropathy. The finding of this kind of radiological lesion, particularly when it is not associated with lesions in the trapezo-metacarpal articulations should indicate the possibility of a diagnosis of ACC and should lead to radiological investigation of other sites.

Adult↗
PubMedDate not supplied

[The stage of articular destruction in the rheumatoid hand].

Function incapacitation of the hand in rheumatoid arthritis was studied on 33 patients (54 hands). 35 were operated on. All cases had reached the stage of articular destructions. The authors emphasize the importance of preserved proximal inter-phalangeal joint for digito-palmar pinch. Thumb unstability was not severely disabling as long as the other digits were normal. However, when it was associated with hyperextension deformities of the other fingers, the hand became useless. Surgical indications in rheumatoid hand were detailed. The importance of restoring thumb function was pointed out.

Arthritis, Rheumatoid↗
PubMed1989

A simplified twenty-eight-joint quantitative articular index in rheumatoid arthritis.

We describe a joint index that includes only 28 joints: 10 proximal interphalangeal joints of the fingers, 10 metacarpophalangeal joints, and the wrists, elbows, shoulders, and knees. These joints are evaluated for swelling, tenderness, and limited motion, with the findings scored as abnormal or normal. The 28-joint index is considerably easier to use than traditional methods, and appears to yield as much information in terms of correlation with other measures of clinical status, including hand radiograph scores, American Rheumatism Association functional class, grip strength, walking time, and activities of daily living questionnaire scores (r = 0.25-0.53, P less than 0.001). Simplified joint counts might facilitate acquisition of quantitative articular data in research and clinical rheumatologic settings.

Arthritis, Rheumatoid↗
PubMed1983

Monophasic synovial sarcoma of spindle-cell type. Epithelial differentiation as revealed by ultrastructural features, content of prekeratin and binding of peanut agglutinin.

Monophasic synovial sarcomas of spindle-cell type and fibrosarcomas were studied by electron and immunofluorescence microscopy for their intermediate filament expression and the binding of peanut agglutinin (PNA). In monophasic synovial sarcomas of spindle-cell type (two cases), frequent cell-to-cell junctions, irregular cytoplasmic processes, and occasional cytoplasmic, tonofilament-like bundles of intermediate filaments were seen by electron microscopy. These features were absent from fibrosarcomas. Immunohistologically, the monophasic synovial sarcomas showed arrays of prekeratin-positive cells in the midst of the vimentin-positive spindle cells. By double fluorescence microscopy, the prekeratin-positive cells also bound PNA, like the epithelial-like cells of the classical biphasic synovial sarcoma. In contrast to monophasic synovial sarcomas, prekeratin-positive cells and arrays of PNA-binding cells, were not seen by immunofluorescence microscopy in fibrosarcomas (seven cases). Thus the prekeratin-content, the binding of PNA lectin, and certain ultrastructural features suggesting early epithelial differentiation, help to distinguish monophasic synovial sarcomas of spindle-cell type from other spindle cell sarcomas.

Adult↗
PubMed2000

[Arthrosis--histology and pathogenetic approaches].

Osteoarthitis is the most common joint disease affecting over 60% of the elderly population. It is characterized by the progressive erosion of articular cartilage leading to incapacity of movement. In the great majority of instances, osteoarthritis appears insidiously, without apparent initiating cause. This primary form is usually oligoarticular involving hip, knee, cervical vertebrae, interphalangeal joints of the fingers or tarsometatarsal joints of the feet. In case of an underlying systemic disease or local injury the cartilage destruction is considered as secondary osteoarthritis. The pathogenesis of primary osteoarthritis suggests an intrinsic disease of cartilage in which biochemical and metabolic alterations result in its breakdown. Within the last decades different models were established which also concentrated on other joint structures such as bone or ligaments. Changes of the subchondral bone were found to precede cartilage damage suggesting a primary alteration of the subchondral region. Other studies concentrated on the metabolic activity of chondrocytes in healthy cartilage of osteoarthritis patients. The precise event that leads to these changes is still not clear. This review concentrates on the histological features in the course of the disease and tries to provide a summary on different pathogenetic concepts.

Aged↗
PubMed2000

Snapping of the proximal interphalangeal joint due to the lateral band.

An unusual case is reported of snapping of the proximal interphalangeal joint (PIPJ) of the right little finger in a 14-year-old girl. The lateral band of the radial side slipped over the peak of the condyle of the proximal phalanx at 40 deg of flexion. The lateral band was cut and sutured to the central slip. At follow-up examination 4 months later, there had been no recurrence.

Adolescent↗
PubMed1980

A hypereosinophilic syndrome mimicking rheumatoid arthritis.

A 58 year old white man presented with an articular syndrome that appeared clinically to be rheumatoid arthritis with nodules. Lack of response to therapy, and laboratory and pathologic data failed to confirm the diagnostic impression. The patient's course over the ensuing seven years was compatible with the hypereosinophilic syndrome. The articular involvement represented soft tissue and synovial fibrinoid degeneration with eosinophilic infiltration. This is the first reported case of articular involvement in the hypereosinophilic syndrome and adds it to the list of processes that can cause hand deformity resembling rheumatoid arthritis.

Ankle Joint↗
PubMed1991

Double dislocations of digits.

We report eight patients who sustained simultaneous dislocations of two joints in a digit. The little finger was involved in five patients.

Adult↗