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PubMed2002

Evidence-based radiology: requirements for electronic access.

RATIONALE AND OBJECTIVES: The purpose of this study was to determine the electronic requirements for supporting evidence-based radiology in today's medical environment. MATERIALS AND METHODS: A software engineering technique, use case modeling, was performed for several clinical settings to determine the use of imaging and its role in evidence-based practice, with particular attention to issues relating to data access and the usage of clinical information. From this basic understanding, the analysis was extended to encompass evidence-based radiologic research and teaching. RESULTS: The analysis showed that a system supporting evidence-based radiology must (a) provide a single point of access to multiple clinical data sources so that patient data can be readily used and incorporated into comprehensive radiologic consults and (b) provide quick access to external evidence in the way of similar patient cases and published medical literature, thus supporting evidence-based practice. CONCLUSION: Information infrastructures that aim to support evidence-based radiology not only must address issues related to the integration of clinical data from heterogeneous databases, but must facilitate access and filtering of patient data in order to improve radiologic consultation.

Evidence-Based Medicine↗
PubMedDate not supplied

Treatment of vaginal infections: candidiasis, bacterial vaginosis, and trichomoniasis.

OBJECTIVE: To describe the signs and symptoms of and recommend treatments for Candida vulvovaginitis, bacterial vaginosis, and Trichomonas vaginitis. DATA SOURCES: Current clinical literature. DATA SYNTHESIS: Patients with candidal vulvovaginitis often present with itching, burning, white discharge, vulvar or vaginal erythema, painful intercourse, and stinging on urination. It is treated with oral or topical antifungal agents. Bacterial vaginosis is characterized by a musty or fishy vaginal odor and a thin, white vaginal discharge. It is treated with oral or topical metronidazole or clindamycin. Patients with trichomoniasis usually complain of profuse, yellow-green discharge and vaginal or vulvar irritation. The standard treatment is a single 2 gram dose of oral metronidazole for both the patient and sexual partners. CONCLUSION: Given the potential adverse effects of the drugs used to treat these conditions, pharmacists are in a unique position to recommend appropriate therapies and to refer patients to other health care providers as needed.

Antifungal Agents↗
PubMedDate not supplied

Smoking cessation: Part 2--Pharmacologic approaches.

OBJECTIVE: To present the concept of nicotine-replacement therapy (NRT) and the pharmacologic approaches, nonprescription and prescription, to smoking cessation. DATA SOURCES: Current clinical literature. DATA SYNTHESIS: NRT can be delivered through a number of different nicotine-containing dosage forms (e.g., gum, patch, nasal spray, oral inhaler). The Agency for Health Care Policy and Research (AHCPR) recommends using the nicotine patches for routine clinical practice and the American Psychiatric Association (APA) recommends the use of the patches and gum as initial pharmacotherapies for smoking cessation. There are no comparative studies indicating the superiority of one form or another at relieving nicotine withdrawal symptoms. Of the other pharmacologic agents used for smoking cessation, bupropion hydrochloride demonstrates the most promise. CONCLUSION: The pharmacist can assist the consumer with the selection of an OTC smoking cessation product and serve as an informational resource to consumers and physicians desiring information on prescription drug products for smoking cessation.

Bupropion↗
PubMed1989

The spectrum of psychiatric morbidity in a defined geographical area.

The concept of 'the pathway to psychiatric care' as described by Goldberg & Huxley (1980) using a scheme of five 'levels' and four 'filters', has provided a useful framework in investigating referral processes in places where health services are organized in a way similar to the British National Health Service. Previous estimates of psychiatric morbidity at each of the levels of this model have been calculated, based upon data obtained from diverse geographical areas and over different time frames. The value of these estimates for service planning is therefore limited by the heterogeneity of the data sources. This paper provides data related to all five levels based upon the same geographical area (South-Verona, Italy) and within the same time frame (one week in 1987). The importance of studying the full spectrum of psychiatric morbidity at all levels in the same area is discussed. In particular, it is shown that the assessment of morbidity in the primary medical care setting (levels 2 and 3) and data about filters 2 and 3 can provide useful information for the evaluation of specialist services (levels 4 and 5) as well as for understanding changes in the provision of specialist care.

Adult↗
PubMed1981

EPA health and environmental effects data analysis system.

This paper discusses the development of a system to organize, store, retrieve, and correlate data pertaining to chemicals and their biological and environmental effects. The particular problems of data identification, acquisition, classification, and automation are discussed in relation to existing data sources and methods of data collection and analysis. The problems of computer software development are also addressed, and a design overview of the system is presented.

Animals↗
PubMed2000

The HCV National Register: towards informing the natural history of hepatitis C infection in the UK.

The aim of this paper is to describe the development of a national hepatitis C register and the completeness of the data it contains. This is a descriptive report of the structure and function of the register, including case definitions, registration and follow-up procedures, and methods used to maximize data quality and to obtain comparative data sources. The register contains data on HCV-infected individuals who acquired their infections on a known date and by a known route; to date all are transfusion recipients identified during the UK lookback exercise, who tested positive or indeterminate for anti-HCV after receiving 'infected' blood issued before the introduction of routine testing of the blood supply for anti-HCV. By 31 December 1999, 871 (87%) of 996 eligible transfusion recipients had been registered, and 984 (99%) flagged in the NHS Central Registers. Registered patients had been infected for an average of 11.1 years (SEM 0.1); around half were being cared for by clinicians with a specialist interest in liver disease. Except for the information on tobacco use, current alcohol use, and hepatitis B status, data were more than 80% complete, and for most variables, more than 90% complete. The consistency of data abstraction was found to be 98% (SEM 0.5). In conclusion, the Register contains high quality anonymised data on one of the largest cohorts of individuals with HCV infections acquired on a known date and by a known route. It could serve as a model for other chronic disease registers; developers may find the structure, design, and methodological issues addressed useful.

Adolescent↗
PubMed2002

Health outcomes and medicaid costs for frail older individuals: a case study of a MCO versus fee-for-service care.

Older individuals receiving both Medicare and Medicaid benefits are known to have a disproportionate burden of illness and high medical care costs. Elder Health, Inc., a private, for-profit managed care organization operating in Maryland under capitation rates from both Medicare and Medicaid, has tailored a medical practice to these individuals, with the stated objective of providing integrated care. This study compared 200 Elder Health patients with a closely matched group of dually eligible older individuals receiving care in fee-for-service practices. There was a baseline in-home structured interview with the patient, followed 1 year later with a telephone interview. Other data sources were Medicaid claims data and Elder Health's utilization records. The outcomes of interest were the patients' health and functional status, their satisfaction with care, rates of use of medical services, and costs to Medicaid. Elder Health patients had similar general health status, better functional status, and greater satisfaction with access to care but less satisfaction with information giving than the fee-for-service group. They received more primary care and preventive services and had less than half the number of hospital days. Costs to Medicaid were nearly identical. Institutional and community-based long-term care costs were not included in the analysis.As pressures mount for the Health Care Financing Administration to expand its prepaid contracts with private health plans and the need for integrated programs increase, quantitative assessment of innovative delivery models such as Elder Health, Inc. will be essential to ensure that patients' and the publics' interests are well served.

Aged↗
PubMed2002

[The Child and Adolescent Health Survey as a source of data for assessment of the essential aspects of health care in childhood and adolescence].

The German National Health Survey for Children and Adolescents aims at collecting representative data on the health status of the population in the 0 to 18 years age bracket. Examination of about 18.000 participants is planned. In this cross-sectional study relevant data concerning health services will be gathered. These include parameters of health care demands, health insurance, vaccination status and drug utilisation. The data collection will start in the first quarter of 2003 and will probably be terminated in the last quarter of 2005. The study design has been tested in a pilot study for one year and was adapted to the demands of this specific health survey. The instruments used for data collection are a self-administered questionnaire as well as a standardised, computer-based medical interview.

Adolescent↗
PubMed2004

[A multidisciplinary mModule for oncological documentation within a hospital information system].

The follow-up documentation of oncological patients in Germany is inadequate in many cases: it is usually limited to a minimal dataset mandated by the epidemiological tumor registers; it is carried out in a paper-based fashion and rarely in a multi-disciplinary context. Parallel documentation efforts can result in redundant or erroneous data and excess work. The introduction of hospital information systems (HIS) allows the implementation of digital oncological documentation systems integrated in surrounding clinical workflows that can provide access to existing data sources as well as data entry and presentation across departmental boundaries. This concept enables the integration of tumor documentation, quality assurance and process optimization within HIS. Feasibility requirements include a high flexibility and adaptability of the underlying HIS to reach a seamless integration of oncological documentation forms within routine clinical workflows. This paper presents the conceptual design and implementation of a modular oncological documentation system at the Muenster University Hospital that is capable of integrating the documentation requirements of multiple departments within the hospital.

Computer Systems↗
PubMedDate not supplied

Psychological development during four years of bereavement: a longitudinal case study.

Bereavement in the lives of college students is more prevalent than many persons realize. A survey replicated 4 times on the Kansas State University campus demonstrated that, at any point in time, over 25% of the students were in the 1st year of grief following the death of a family member and nearly 30% in the 1st year of grief following the death of a friend. Grief work can hinder traditional-age college students from resolving normal developmental tasks, such as forming autonomous lives, developing a clear sense of direction, and entering into lasting, intimate relationships. This article provides longitudinal case study information about a traditional-age college student following the death of her father. The data come from multiple sources. Data from the Impact of Events Scale document changes in intrusive and avoidant thoughts and images; journal entries show changes in the student's ongoing relationship with her father, coping with his death and subsequent events colored by her bereavement, and life lessons; data from the Grant Foundation Bereavement Inventory show changes in the student's attachment, reunion fantasies, disbelief about her father's death, identification with her father, and feelings of disloyalty as time passed. Comparisons are made to responses of 80 bereaved students who participated in a separate longitudinal study.

Adolescent↗
PubMed2002

The communication of information about older people between health and social care practitioners.

AIM: to provide an evidence base for strategies, and effectiveness of the transfer of patient information between hospital and community for older people with physical illness. DESIGN: a systematic review of qualitative and quantitative literature. SEARCH STRATEGY: literature from medical, health-related and social science databases as well as work in progress from national databases, the Internet, British PhD theses and other grey literature and policy documents. SELECTION CRITERIA: literature relating to similar healthcare systems published between January 1994 and June 2000 on hospital discharge planning. Empirical studies from peer reviewed sources; theoretical papers from non-peer reviewed sources; research papers from non-peer reviewed sources and professional documents. DATA COLLECTION AND ANALYSIS: extracted data from empirical studies under the headings of location, sector, research questions and study design and duration. We made structured summaries of all other data sources and used them to supply context and background. We categorized literature and analysed it in terms of method and analysis, quality and strength of evidence and its relevance to the research questions. We synthesized the results and presented them in terms of answers to our research questions. RESULTS: a database of 373 potentially relevant studies and of these, 53 were accepted for further analysis. Thirty-one were empirical studies, most of which were qualitative or a combination of qualitative and quantitative in design. The most effective strategy for transferring information is the appointment of a 'key worker', who can provide a point of contact for workers from hospital and community. Nevertheless, problems have arisen because both settings are under pressure and pursuing different goals. Neither setting is fully aware of the needs, limitations and pressures of the other. CONCLUSION: raised awareness and the establishment of common goals are the first steps needed to bridge the divide between health and social care staff in hospital and the community.

Aged↗
PubMed2006

Measurement and reporting of burden of disease for hepatitis A: results of the EUROHEP.NET feasibility survey.

BACKGROUND: European countries use a wide variety of surveillance systems and prevention measures for viral hepatitis. Each system is adapted to the local situation and an overview was never mapped out at European level. The EUROHEP.NET Project is a European Commission-funded feasibility study for a future network on surveillance and prevention of vaccine-preventable hepatitis. We analysed the measurement and reporting of burden of disease for hepatitis A (HA) and B (HB) in the participating countries. METHODS: Twenty-eight countries were invited to participate in this study. An online survey was available from the project's website (www.eurohep.net). The questions concerned the organisation of the surveillance system, case definition, burden of disease, epidemiology, and vaccination strategies. The responses on data sources and the numeric data related to burden of disease for HA for the period 1997-2001 were analysed. RESULTS: Twenty-two countries completed the survey for hepatitis A. Data on total number of hospitalisations and deaths were available from 17 and 18 countries, respectively, although sometimes not complete. Data on hospitalisation days, number of liver transplants and proportion of these due to HAV were often not available. CONCLUSION: Surveillance systems on burden of disease for hepatitis A show a wide diversity among the participating countries. The introduction of a standardised system of data collection at the European Union level according to ICD-10 but respecting the local current practices is a primary need, especially for data that should be collected in all countries, like hospitalisation and mortality. A link to surveillance databases is also strongly recommended.

Adolescent↗
PubMed2005

Complications following bilateral prophylactic mastectomy.

BACKGROUND: Bilateral prophylactic mastectomy significantly decreases breast cancer risk, but complications of the procedure have only been described in single-site studies. We describe the frequency and type of complications in women who underwent bilateral prophylactic mastectomy in a multisite community-based cohort. METHODS: Women aged 18-80 years undergoing bilateral prophylactic mastectomy without a personal history of breast cancer at one of six health plans were eligible. We identified women from automated data sources, then reviewed hospital data, ambulatory notes, and other chart elements to confirm eligibility and obtain all charted information about complications and surgeries performed after prophylactic mastectomy, including reconstructive procedures. Reconstructions were characterized by type (implant vs. tissue graft). Complications were noted for a 1-year period after any surgical procedure. RESULTS: We identified 269 women with prophylactic mastectomy who were followed for a mean of 7.4 years. Their mean age was 44.9 years. Nearly 80% undertook reconstruction, most with prosthetic implants. One or more complications occurred in 64%. The most common complications were pain (35% of women), infection (17%), and seroma (17%). Women with no reconstruction had fewer complications (mean of .93) than women who had implant (2.0) or tissue graft (2.4) reconstruction procedures (differences from no reconstruction: 1.07 [95% confidence interval = 0.36 to 1.77] and 1.50 [95% confidence interval = 0.44 to 2.56] respectively). Delay of reconstruction after mastectomy was associated with a borderline-significant higher risk of complications (80.6%) compared to simultaneous reconstruction (64.0%, P = .055). CONCLUSION: We found that almost two-thirds of women undergoing bilateral prophylactic mastectomy had at least one complication following surgery. Further work should be done to minimize and to understand the effect of complications of bilateral prophylactic mastectomy.

Adolescent↗
PubMed2000

Posthospitalization home health care use and changes in functional status in a Medicare population.

OBJECTIVE: The objective of this work was to estimate the effect of Medicare beneficiaries' use of home health care (HHC) for 6 months after hospital discharge on the change in functional status over a 1-year period beginning before hospitalization. DATA SOURCES AND STUDY SETTING: Data came from the Medicare Current Beneficiary Survey, which is a nationally representative sample of Medicare beneficiaries, in-person interview data, and Medicare claims for 1991 through 1994 for 2,127 nondisabled, community-dwelling, elderly Medicare beneficiaries who were hospitalized within 6 months of their annual in-person interviews. STUDY DESIGN: Econometric estimation with the instrumental variable method was used to correct for observational data bias, ie, the nonrandom allocation of discharged beneficiaries to the use of posthospitalization HHC. The analysis estimates a first-stage model of HHC use from which an instrumental variable estimate is constructed to estimate the effect on change in functional status. PRINCIPAL FINDINGS: The instrumental variable estimates suggest that HHC users experienced greater improvements in functional status than nonusers as measured by the change in a continuous scale based on the number and mix of activities of daily living and instrumental activities of daily living before and after hospitalization. The estimated improvement in functional status could be as large as 13% for a 10% increase in HHC use. In contrast, estimation with the observational data on HHC use implies that HHC users had poorer health outcomes. CONCLUSIONS: Adjusting for potential observational data bias is critical to obtaining estimates of the relationship between the use of posthospitalization HHC and the change in health before and after hospitalization. After adjustment, the results suggest that efforts to constrain Medicare's spending for HHC, as required by the Balanced Budget Act of 1997, may lead to poorer health outcomes for some beneficiaries.

Activities of Daily Living↗