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[Functional constipation syndrome: experience in the use of sour milk products and biologically active food supplements in the complex treatment of patients].

Sour milk product "Bifeedock" and biologically-active food additives of "Litovite" and "Pektsecom" type are used in the overall treatment of functional constipation and accompanying colon disbacteriosis of I and II degree. They help to improve the clinical symptomatics and the functional state of the gastrointestinal tract. According to the data analysis, the elimination of the colon stasis results in the improved microbiocenosis expressed in the suppression of growth of conditionally pathogenic microflora. It also stimulates the growth of the symbiotic elements of microbiota (bifidobacteria, lactobacteria and the intestinal E. coli).

Adult↗

Management of chemotherapy-induced diarrhea and constipation.

This article reviews the incidence, etiology, pathophysiology, and assessment of diarrhea and constipation related to chemotherapy. Protocols for treatment are presented. The nurse's role in prevention, patient education, assessment, and treatment is emphasized.

Algorithms↗

[An exercise program for women suffering from constipation].

An activity programme facing the psychological and psychosomatic aspects of constipation has been developed and put into practice. The experience of exceeding the limits in respect of common orientation and the way of life they are used was an essential part of this programme as the reflection of the "female" way of behaving and moving was relevant. The evaluation showed: the self-concept "living without symptoms" and the potential effect experienced by the participants of the course were so similar, that we can expect, step by step, a lasting change concerning their well-being and way of life and thereby a reduction of symptoms due to the outlined programme.

Adult↗

[Biofeedback therapy for constipation and fecal incontinence].

Constipation and fecal incontinence are problems that are frequently encountered in daily practice. Over the last decade biofeedback therapy has emerged as a useful adjunct for the treatment of these problems. Biofeedback therapy is a learning process that is based on "operant conditioning" techniques. Biofeedback training aims to restore a degree of continence that enables patients to resume their activities to a satisfactory level with good success rates and prolonged benefits. The technique requires height levels of motivation not only in the patients but also in the instructor who is providing verbal feedback about the adequacy of a patients performance.

Biofeedback, Psychology↗

[Differentiated diet therapy in chronic intestinal diseases with predominance of the dyskinetic constipations syndrome].

On the ground of clinical observations, studies on the motor-evacuatory functions of the gastro-intestinal tract and its regulation values in dynamics a differentiated dietotherapy and a special complex of exercise therapy have been devised for patients with chronic colites and enterites marked by predominance of constipation. Among basic principles of this dietotherapy were: the content of all nutrients corresponding to physiological standards with the amount of protein increased up to 135 g, creating conditions conducive to sparing of the stomach, pancreas, liver and biligenic organs through exclusion of strong stimulators of the digestive and bile secretion glands, of substrates irritating the liver, regulation of the motor-evacuatory function of the gastro-intestinal tract by a graded increase in the amount of cellular membranes, progressively rising parallel with weakening of the symptoms pointing to irritation of the gastro-intestinal tract organs. The complex set of physical exercises included: those of general tonic and improving the prelum abdominale muscles tonicity, mechanically stimulating the motor function of the stomach and the intestines, periodically changing the intra-abdominal pressure, both upwards and downward.

Abdomen↗

Dyspepsia, irritable bowel syndrome, and constipation: review and what's new.

Functional gastrointestinal disorders are collections of symptoms attributable to the gastrointestinal tract in the absence of mucosal, structural, or biochemical disease. The two most common disorders, irritable bowel syndrome and functional dyspepsia, have common etiopathogenetic features, notably psychosocial disturbances, dysmotility, heightened sensitivity, and, possibly, an association with a postinfective state. The third condition is constipation, in which transit disorders and abnormal evacuation represent disturbances of function that are amenable to therapy. This review is an update of the control mechanisms, pathophysiology, investigation, and potential pharmacotherapies of these disorders. Serotonergic and adrenergic agents and neurotrophic factors are among the novel approaches that may have a significant impact on these disorders.

Colonic Diseases, Functional↗

[A rare cause of constipation: neurinoma of the fourth lumbar nerve. Case report and review of the literature ].

Constipation is a symptom not to be neglected, especially if the complaint is recent. We report a case where this symptom was the only clinical manifestation of a voluminous retroperitoneal tumor. The tumor was found to be a neurilemmoma of the fourth right lumbar roots, confirmed at pathological examination. Manifestations of extradural neurinomas generally result from compression of neighboring structures. The best preoperative diagnosis approach is magnetic resonance imaging but histology is required for confirmation. The close relations the tumor mass maintains with the unaffected nerve fibers makes resection difficult without postoperative functional consequences. Surgeons discuss the relevance of partial excision in order to preserve the nerve root in case of a benign slow-growing tumor. There does however appear to be a significant recovery of muscle strength even in case of total resection.

Aged↗

[Cryoamplipulse therapy in treating patients with chronic constipation].

120 patients with chronic constipation (CC) were examined using assessment of the immune status, rectoromanoscopy, esophagogastroduodenoscopy, myography, stool examination for volatile fatty acids and dysbacteriosis. The patients were divided into three groups. Group 1 (n = 58) received cryoamplipulsetherapy, group 2 (n = 29)--creotherapy, group 3 (n = 33)--amplipulsetherapy. Changes in clinical and functional indices show that the response in group 1, 2 and 3 was 88, 75 and 68%, respectively.

Adolescent↗

[Anorectal manometry. A new method for the evaluation of continence, incontinence and chronic constipation].

643 ano-rectal electromanometric investigations were carried out in 438 children with different ano-rectal diseases including myelomeningocele, Hirschsprung's disease, anal atresia and chronic constipation, as well as in healthy premature, new-born and older infants. The reliability of the recorded physiological and pathological parameters was found to be significant in 87,2%. Electromanometry is shown to be an important new method of assessing ano-rectal continence.

Constipation↗

Constipation in childhood.

Most commonly, constipation in the infant is functional, with increased tone of colonic smooth muscle. Hirschsprung's disease is the best known of the infrequent organic causes. Treatment includes reassurance of parents, use of sugars, fluids and bulk and care of fissures. Voluntary stool withholding occurs in older children, who present with a variety of symptoms. Medicines are required to restore the functional capacity of the colon after chronic distortion by stool. This must be combined with psychologic help.

Age Factors↗

A national audit of chronic constipation in the community.

This article presents the first available data on current national bowel-care standards. It involves 923 patients based at home or in residential/nursing homes. The baseline findings indicate problems of poorly controlled constipation, a high level of impaction and high use of rectal interventions. All the patients have been receiving laxatives regularly and 42 per cent were on combination laxative therapy. The audit provides evidence of complex, ineffective and/or inappropriate laxative prescribing linked to sub-optimal bowel care.

Aged↗

Measuring colonic transit time in chronic idiophatic constipation.

INTRODUCTION AND OBJECTIVES: Colonic transit time can define three types of delay: right colon (colonic inertial), left colon and recto sigmoid. The aim of this study is to compare clinic characteristics and manometric results among the different groups with segmental colonic transit disorder. PATIENTS AND METHODS: 61 subjects were included in our study (5 men and 56 women) with and average age of 47.5 years (range: 17-84 years). We carried our a study of segmental and total colonic transit time, with the use of radio-opaque markers and sequential abdominal X-rays. We considered that transit time was prolonged when it was longer than 72 hours, and segmental transit time, when right colon was longer than 22 hours, left colon 37.2 hours and recto-sigmoid 37.2 hours. We included different clinic data: age, sex, place of residence stool frequency, abdominal pain, painful evacuation, incomplete evacuation, evacuation desire, dietary fibre intake, use of laxatives. We practised anorectal manometry in 20 patients. RESULTS: The average total colonic transit time was 38.2 hours in normal transit and 103 hours with disorder. The frequency in the three colonic segments, when there was a long total colonic transit time, was: 40% in the left colon, 33% in the recto-sigmoid and 27% in the right colon. We analysed the clinical characteristics of these three groups, finding more frequency of painful evacuation and defecation desire and lower dietary fibre intake in recto sigmoid. The most important abnormality in anorectal manometry was the hiposensitivity in the anorectal area, that only appeared in subjects with long segmental transit time in the right colon (colonic inertia), statistically significant. CONCLUSIONS: The measurement of colonic transit time with radio-opaque markers is a simple technique that allows for the objective detection of the different groups of patients with chronic idiopathic constipation. The exact typification of the abnormality is important for the individualization of each treatment.

Adolescent↗

Colonic pacing in patients with constipation due to colonic inertia.

BACKGROUND: The colon exhibits electrical activity in the form of pacesetter potentials (PPs) and action potentials (APs); no activity is recorded in total colonic inertia (TCI). Electrical activity mediates colonic motility. We have elsewhere demonstrated that 4 pacemakers initiate colonic electric activity. We investigated the hypothesis that the absence of electric activity in TCI is due to non-functioning pacemakers and that their stimulation produces colonic motility and defecation. MATERIAL/METHODS: 19 patients with TCI were divided into 2 groups: a study group of 11 patients (age 42.6 +/- 6.8 years; 7 women) and a control group of 8 patients (age 41.4 +/- 6.3 years, 5 women). 7 healthy volunteers (age 40.9 +/- 6.1 years, 5 women) were also studied. Pacing electrodes were endoscopically hooked to colonic mucosa: one stimulating and 2 or 3 recording. Stimulating electrodes were applied to the 4 potential pacemaker sites located at the cecal pole, the cecocolonic junction, the mid-transverse colon, and the colosigmoid junction. Electrical activity was recorded before and during electrical stimulation. RESULTS: Colonic pacing of healthy volunteers caused a significant increase in the frequency, amplitude and conduction velocity of basal electric waves. Colonic pacing in the study group produced PPs and APs, which varied between colonic segments. No waves were recorded from the control group in which the pacemakers were not activated. CONCLUSIONS: Colonic pacing produces electrical activity in patients with TCI. This method can be applied for the treatment of constipation in these patients.

Action Potentials↗

[Management of cancer treatment-related diarrhea and constipation].

Digestive complications are frequent dose-limiting side-effect of chemotherapy. Diarrhea and constipation can affect quality of life and alter optimum treatment efficacy. The incidence and the severity of these toxicities have to be systematically evaluated in order to provide specific curative and preventive treatments. This review shows the recommended guidelines for the treatment of chemotherapy-induced diarrhea and the recent therapeutic approaches. The management of gastrointestinal graft-versus-host disease and neutropenic enterocolitis is also described. Prevention and early recognition is critical to avoid sever life-threatening complications and improve quality of life.

Antineoplastic Agents↗

The efficacy of cisapride vs. placebo and diet in patients with chronic constipation.

The effects of cisapride (10 mg three times daily) on the stool evacuation characteristics, laxative consumption (symptom diary) and motility pattern (rectoanal manometry) were assessed in patients with chronic idiopathic constipation who fulfilled Rome II criteria. After a 14-day basal period on a diet rich in fiber (phase I), patients were treated with placebo (n = 20) or cisapride (n = 19) (phase II). Anorectal manometry was performed at the end of each phase. The study was controlled, randomized and double blind. Side effects related to the use of cisapride were noted and found to be mild. Cisapride and placebo increased stool frequency from 4 (1-11) to 7 (14-12) (p < 0.001) and from 4 (2-10) to 6 (2-11) (p < 0.05) per week, respectively. Straining was decreased from 69.0% to 39.7% in the cisapride (p < 0.0001) group, and from 79% to 35% (p < 0.0001) in the placebo group. Both cisapride and placebo decreased the feeling of incomplete evacuation from 91.7% to 37.5% (p < 0.0001) and from 82.7% to 39.2% (p < 0.0001), respectively. Cisapride reduced the need of laxatives and showed a tendency to normalize stool consistency but did not influence any other symptom or bowel motility parameter.

Adult↗

[A case of obstructive ileus following the upper Gi barium swallow study with condensed barium due to severe constipation].

A 64-year-old woman visited my clinic with complaints of abdominal distension, constipation, and nausea. Since abdominal X-ray showed severe obstructive ileus following the upper GI barium swallow study, the patient was sent immediately to Saga Medical School Hospital for the emergency operation. As the result of the left hemicolectomy, two obstructive lesions were found at the sigmoid colon and the transverse colon. Nowadays, as the population of aged people increases and Japanese diet changes, colon cancers are increasing more rapidly. Since the half of colon cancers doesn't have any clinical symptoms of obstruction, the upper GI barium swallow study with condensed barium might lead a patient to some type of dangerous situation.

Adenocarcinoma↗