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The influence of emotional valence on age differences in early processing and memory.

This study examined older and younger adults' attentional biases and subsequent incidental recognition memory for distracting positive, negative, and neutral words. Younger adults were more distracted by negative stimuli than by positive or neutral stimuli, and they correctly recognized more negative than positive words. Older adults, however, attended equally to all stimuli yet showed reliable recognition only for positive words. Thus, although an attentional bias toward negative words carried over into recognition performance for younger adults, older adults' bias appeared to be limited to remembering positive information.

Adolescent↗

Preserved conceptual priming in Alzheimer's disease.

We assessed Alzheimer's disease (AD) and healthy older adult control (HC) group performance on: (1) a conceptual priming task, in which participants had to make a semantic decision as to whether a degraded picture of an object encountered previously belonged to the category of living or non-living things; and (2) a recognition memory task. The AD group showed a dissociation between impaired performance on the recognition task and preserved priming for semantic decisions to degraded pictures. We argue that it is not whether priming is conceptual or perceptual that is important for the observation of priming in AD, rather it is the nature of the response that is required (c.f., Gabrieli et al., 1999).

Aged↗

Perirhinal cortex neuronal activity related to long-term familiarity memory in the macaque.

Lesion studies suggest that the perirhinal cortex plays a role in object recognition memory. To analyse its role, the activity of single neurons in the perirhinal cortex was recorded in three rhesus monkeys (Macaca mulatta) performing a delayed matching-to-sample task with up to three intervening stimuli. A set of familiar visual stimuli was used. Some neurons had activity related to working memory, in that they responded more to the sample than to the match image within a trial, as shown previously. However, when a novel set of stimuli was introduced, the neuronal responses were on average only 47% of the magnitude of the responses to the familiar set of stimuli. Moreover, it was shown in eight different replications in three monkeys that the responses of the perirhinal cortex neurons gradually increased over hundreds of presentations of the new set of (initially novel) stimuli to become as large as with the already familiar stimuli. The mean number of 1.3-s presentations to induce this effect was 400 occurring over 7-13 days. These results show that perirhinal cortex neurons represent the very long-term familiarity of visual stimuli. A representation of the long-term familiarity of visual stimuli may be important for many aspects of social behaviour, and part of the impairment in temporal lobe amnesia may be related to the difficulty of building representations of the degree of familiarity of stimuli.

Action Potentials↗

Revelation without presentation: counterfeit study list yields robust revelation effect.

This study explores the revelation effect, a recognition memory phenomenon that occurs when test items (or related items) are specially processed before recognition judgment. These revealed items, whether targets or lures, receive a positive response bias. Although the effect occurs across various conditions, it has not been shown to occur when participants make judgments unrelated to episodic memory. We investigated whether the effect would occur when a recognition decision was nominally one of episodic memory, but when a complete episodic event had not occurred. Specifically, participants listened to noise that allegedly masked a list of words (in fact, no words existed). A revelation effect occurred with this pseudo-subliminal procedure, suggesting that the revelation effect need not rely on stimuli recalled through episodic memory but only a specific event to recall. The effect did not occur when participants simply guessed whether words were on an unheard list or made semantic judgments.

Humans↗

Recovery of memory after severe closed head injury: dissociations in recovery of memory parameters and predictors of outcome.

This study examined selective reminding and recognition memory performance of 21 severe closed-head injured patients tested within 6 months of regaining consciousness and then again after at least 1 year. Performances on selective reminding parameters were highly correlated and patients performed significantly worse at both testings than did hospitalized controls matched for age, education, and sex. Patients improved from testing 1 to testing 2 on only four of six memory variables. Average Impairment Rating at testing 1 was a marginally better predictor of memory performance at testing 2 than was length of coma. Results are discussed in terms of (a) utility of selective reminding parameters and predictors of outcome and (b) dissociations in recovery of memory parameters.

Adult↗

[The ideal self in processing trait information].

The ideal self is defined as a cognitive structure which contains representations of desired and undesired states for the self. Its structural properties and role in processing trait informations are examined by asking subjects to make "ideal self" referent ratings, and comparing their performance on various cognitive tasks. Results indicate that the ideal self leads to faster processing and better memory of relevant information as compared to neutral items. Data from the recognition memory test revealed a significant bias in the recognition of relevant but nonpresented items (Exp. 1). Relevant trait items are more easily translated into concrete behavioral descriptions (Exp. 2). Information about the actual self are abundant in the ideal self relevant domains (Exp. 3). Total results suggest that the ideal self is a rich, well-integrated cognitive structure, which serves as a frame of reference in processing information. However, memory of trait information which is negatively relevant to the ideal self is to some extent inhibited, suggesting that affect also influences the processing of trait information.

Adolescent↗

[Selective use of the Eight-Word subtest in psychogeriatrics].

Performance on the Amsterdam Dementia Screening Test (ADS) and the Expanded Mental Control Test (EMCT) was examined in a consecutive sample of 204 attendants of a psychogeriatric day care department. The ADS has six subtests: picture recognition, orientation, drawing alternating sequences, category fluency, copying geometric figures, and free recall with immediate yes-no recognition of eight words. As was determined by logistic regression analysis, attentional control (EMCT), category fluency and picture recognition scores were significant predictors of verbal free recall. Recognition memory for pictures and a short orientation questionnaire (month, year, place) predicted word recognition performance. In 97% of the subjects with poor scores on EMCT and category fluency, an equally poor free recall performance was found. In those cases the incremental diagnostic value of the free recall test is doubtful. Since word recall and word recognition were conceptually related to working memory and episodic memory respectively, the two components of the verbal learning test allow detection of differential impairments of these memory systems.

Aged↗

Short-term episodic memory for visual textures: a roving probe gathers some memory.

Cognition is shaped by the way that past experiences are represented in memory. To examine the representation of recent visual experiences, we devised a novel procedure that measures episodic recognition memory for synthetic textures. On each trial, two brief study stimuli were followed by a probe, which either replicated one of the study stimuli or differed in spatial frequency from both. The probe's spatial frequency roved from trial to trial, testing recognition with a range of differences between probe and study items. Repeated testing of recognition generated mnemometric functions, snapshots of memory strength's distribution. The distributional characteristics of the mnemometric functions rule out several hypotheses about memory representation, including the hypothesis that representations are prototypes constructed from previously seen stimuli; instead, stimuli are represented in memory as noisy exemplars.

Adult↗

On the discovery of novel wordlike units from utterances: an artificial-language study with implications for native-language acquisition.

In 4 experiments, adults were familiarized with utterances from an artificial language. Short utterances occurred both in isolation and as part of a longer utterance, either at the edge or in the middle of the longer utterance. After familiarization, participants' recognition memory for fragments of the long utterance was tested. Recognition was greatest for the remainder of the longer utterance after extraction of the short utterance, but only when the short utterance was located at the edge of the long utterance. These results support the incremental distributional regularity optimization (INCDROP) model of speech segmentation and word discovery, which asserts that people segment utterances into familiar and new wordlike units in such a way as to minimize the burden of processing new units. INCDROP suggests that segmentation and word discovery during native-language acquisition may be driven by recognition of familiar units from the start, with no need for transient bootstrapping mechanisms.

Adult↗

Mediodorsal thalamic function in scene memory in rhesus monkeys.

Three monkeys were trained preoperatively in a scene memory task which is analogous, in some ways, to human episodic memory. The same animals were also trained in object-reward association memory. Following bilateral ablations of almost the entire magnocellular division of the mediodorsal thalamic nucleus, the animals were impaired both in scene memory and in object-reward association memory. These results, combined with recent results in object recognition memory from monkeys with mediodorsal thalamic lesions, show that the impairment produced by this lesion is more general, affecting a broader range of memory tasks, than the impairment which is produced in monkeys by lesions restricted to the hippocampus-fornix-mamillary system. It is also more severe than the effect of lesions limited to the medial part of the magnocellular division of the mediodorsal thalamic nucleus. These findings extend the evidence that the magnocellular division of the mediodorsal thalamic nucleus has an important and general role in memory, and they are consistent with the proposal that lesions of the magnocellular division of that nucleus have their effect by disrupting the function of prefrontal cortex.

Animals↗

Brain responses of explicit and implicit memory: An event-related potential study.

Implicit memory is acquired by an unintentional or unconscious learning. Recognition memory involves either automatic knowing or consciously controlled remembering. We provided an event-related potential paradigm capable of differentiating memory for the explicitly learned, implicitly learned and unstudied materials. In the explicit memory, we obtained both frontal (controlled retrieval) and parietal (recollection) old/new effects. In the implicit memory, we found persistent occipitotemporal activation (visual priming) and late attenuation in the temporoparietooccipital (repetition suppression). Event-related potential provides an insight into the dissociable mechanism of memory function that supports the dual process model with an enhanced temporal resolution on the dynamic process of both explicit perceptual learning and implicit perceptual priming.

Adult↗

Memory for faces: testing method, encoding strategy, and confidence.

Signal detection theory predicts a square root 2 recognition memory performance advantage for the two-alternative forced choice (2AFC) procedure over the yes-no (YN) procedure. In auditory psychophysics this advantage has been related to greater demands on memory in the YN task. The present experiment tested this prediction by assessing face-recognition accuracy and confidence in 72 college student subjects. Testing method (2AFC or YN) and encoding instructions (standard, overall gestalt, or distinctive feature scan) were varied, the latter in an effort to vary trace strength to see whether stronger traces would yield a lesser 2AFC advantage. A 1-week retention test revealed an overall 2AFC advantage of 1.61 and superiority of gestalt and feature-scan instructions over standard ones. While confidence and accuracy were related both within and across subjects, 2AFC subjects were significantly more confident than YN ones. Intriguingly, more efficient encodings resulted in a greater, rather than a lesser 2AFC advantage.

Adult↗

Effects of size changes on memory for words and pictures.

The effects of changing the size of stimuli between learning and recognition sessions were examined for word and picture materials. Size changes did not affect correct recognition of items as new or old, for either words or pictures. However, size alteration impaired recognition memory for the size of word stimuli. With pictures, impaired size recognition was noted with changes only from large to small.

Adult↗

States of awareness across multiple memory tasks: obtaining a "pure" measure of conscious recollection.

Four experiments were conducted to examine the nature of recollective experience across different explicit memory tests. Experiments 1 and 2 showed that the proportion of retrieved items that were given Remember responses were equivalent across free recall, category cued recall, category plus letter cued recall, and recognition memory tests unlike the result reported by Tulving [Can. Psychol. 26 (1985) 1]. Experiments 3 and 4 revealed that Remember judgments are influenced by both conceptual and perceptual variables not only in the recognition task but in other explicit memory tasks as well. Taken together, the empirical evidence from this study demonstrates that explicit memory performance is accompanied by different states of awareness not only in recognition but also across other memory tasks including free recall.

Awareness↗

Human hippocampal activation in the delayed matching- and nonmatching-to-sample memory tasks: an event-related functional MRI approach.

The delayed matching-to-sample (DMS) and delayed nonmatching-to-sample (DNMS) memory tasks are standard tools used to probe visual recognition memory in human and nonhuman primates. Previous research indicates that structures within the medial temporal lobe, including the hippocampus, make up a crucial memory circuit for successful performance on these tasks. In the present investigation, event-related functional magnetic resonance imaging was used to examine activation in the hippocampus proper during these memory tasks relative to a perceptuomotor task involving the same stimuli. The results indicate that both memory tasks elicited greater activation in the right hippocampus during the encoding phase. These findings are consistent with the work from human patients and animal studies, indicating hippocampal involvement in the DMS and DNMS tasks.

Adult↗

Hippocampal contributions to episodic encoding: insights from relational and item-based learning.

The integrity of the hippocampus and surrounding medial-temporal cortices is critical for episodic memory, with the hippocampus being posited to support relational or configural associative learning. The present event-related functional magnetic resonance imaging (fMRI) study investigated the role of specific medial-temporal lobe structures in learning during relational and item-based processing, as well as the extent to which these structures are engaged during item-based maintenance of stimuli in working memory. fMRI indexed involvement of the hippocampus and underlying cortical regions during performance of two verbal encoding conditions, one that required item-based maintenance of word triplets in working memory and the other that entailed the formation of inter-item associations across the words in each triplet. Sixteen subjects were scanned using a rapid event-related fMRI design while they encountered the item-based and relational processing trials. To examine the correlation between fMRI signal in medial-temporal structures during learning and the subject's subsequent ability to remember the stimuli (a measure of effective memory formation), subjects were administered a yes-no recognition memory test following completion of the encoding scans. Results revealed that the hippocampus proper was engaged during both relational and item-based processing, with relational processing resulting in a greater hippocampal response. By contrast, entorhinal and parahippocampal gyri were differentially engaged during item-based processing, providing strong evidence for a functional neuroanatomic distinction between hippocampal and parahippocampal structures. Analysis of the neural correlates of subsequent memory revealed that activation in the bilateral hippocampus was reliably correlated with behavioral measures of effective memory formation only for those stimuli that were encoded in a relational manner. Taken together, these data provide evidence that the hippocampus, while engaged during item-based working memory maintenance, differentially subserves the relational binding of items into an integrated memory trace so that the experience can be later remembered.

Adult↗

Memory lost and regained following bilateral hippocampal damage.

We present a longitudinal neuropsychological study (31 examinations over a period of 18 months) of patient DE DF demonstrated bilateral atrophy of the hippocampal formation and globus pallidus resulting from carbon monoxide poisoning. Eighteen months after the event, the volume of the hippocampal formation was reduced by 42% on the left side and 28% on the right. The patient initially presented with a severe global amnesia. Then, he showed a gradual, yet selective recovery of episodic memory function. Verbal free recall and spatial memory performance remained reduced, whereas immediate word recall and recognition memory, as well as picture learning and memory, improved to levels at the lower range of normal performance. Interestingly, nonspatial associative learning was never much impaired and recovered completely by the end of testing. These data are taken as evidence that the human hippocampal formation does not equally support different forms of episodic memory.

Adult↗

Word frequency effects in associative and item recognition.

The word frequency effect (WFE) has been taken as evidence that recall and recognition are in some way fundamentally different. Consequently, most models assume that recall and recognition operate via very different retrieval mechanisms. Experiment 1 showed that the WFE reverses for associative recognition, which requires discrimination between intact test pairs and recombinations of study list words from different study pairs. Experiment 2, in which word triples were used, revealed an interaction between word frequency and test type: for item recognition, performance was better for low-frequency words; however, for associative recognition and free recall, performance was better for high-frequency words. In Experiment 3, item recognition was tested: although overall performance was better for low-frequency words, the recognition advantage for items in intact pairs was larger for high-frequency words, suggesting two components in recognition memory. These results imply common mechanisms in recall and recognition. Theoretical implications are discussed within the framework of the SAM model.

Adult↗