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PubMed2006

Implementing practice guidelines: a workshop on guidelines dissemination and implementation with a focus on asthma and COPD.

The present supplement summarizes the proceedings of the symposium "Implementing practice guidelines: A workshop on guidelines dissemination and implementation with a focus on asthma and COPD", which took place in Quebec City, Quebec, from April 14 to 16, 2005. This international symposium was a joint initiative of the Laval University Office of Continuing Medical Education (Bureau de la Formation Médicale Continue), the Canadian Thoracic Society and the Canadian Network for Asthma Care, and was supported by many other organizations and by industrial partners. The objectives of this meeting were to examine the optimal implementation of practice guidelines, review current initiatives for the implementation of asthma and chronic obstructive pulmonary disease (COPD) guidelines in Canada and in the rest of the world, and develop an optimal strategy for future guideline implementation. An impressive group of scientists, physicians and other health care providers, as well as policy makers and representatives of patients' associations, the pharmaceutical industry, research and health networks, and communications specialists, conveyed their perspectives on how to achieve these goals. This important event provided a unique opportunity for all participants to discuss key issues in improving the care of patients with asthma and COPD. These two diseases are responsible for an enormous human and socioeconomic burden around the world. Many reports have indicated that current evidence-based guidelines are underused by physicians and others, and that there are many barriers to an effective translation of recommendations into day-to-day care. There is therefore a need to develop more effective ways to communicate key information to both caregivers and patients, and to promote appropriate health behaviours. This symposium contributed to the initiation of what could become the "Canadian Asthma and COPD Campaign", aimed at improving care and, hence, the quality of life of those suffering from these diseases. It is hoped that this event will be followed by other meetings that focus on how to improve the transfer of key recommendations from evidence-based guidelines into current care, and how to stimulate research to accomplish this.

Asthma↗

PubMed2006

Role of scientific societies in implementation of stroke guidelines and clinical pathways promotion.

Both inpatients and outpatients affected by cerebrovascular diseases currently request various clinical expertise, mainly expressed by specialties involved in neurological and in cardiovascular topics. In many cases each specialty tends to assume a leading role in proposing guidelines minimising the aspects not commonly treated; the SPREAD experience allowed a valid cooperation and the confluence of selective opinions toward the goals of stroke care and the clinical decision supported by evidence. In the last years, some hospitals proposed a stroke clinical pathway performed on the basis of integrated actions of all specialists involved in stroke care. The organisation core is the stroke unit but a strong point is represented by the relationship with the emergency system and the post-discharge organisation. The Italian Stroke Forum is a scientific society linking several specialties, approaching different aspects of cerebrovascular disease, ranging from epidemiology to pathophysiology, diagnosis, medical and surgical treatment, and rehabilitation. For these characteristics the proposed guidelines published in SPREAD are accepted by 34 scientific societies and are largely adopted as the scientific background of the stroke clinical pathway. The Cerebrovascular Disease Association, was proposed as a Study Group of the Italian Neurological Society, has a similar organisation regarding the different neurological aspects involved in stroke care, from neuroepidemiology to neurorehabilitation. Recently, the American Board of Medical Specialties approved a Certification in Vascular Neurology as a new subspecialty requested by the American Academy of Neurology; maybe in the near future a Consensus Conference has to be organised in Italy also, with the aim of defining a common management of stroke and promoting the growth of vascular neurology disease as an independent area of medical expertise.

Cerebrovascular Disorders↗

PubMed1996

Local clinical guidelines: description and evaluation of a participative method for their development and implementation.

BACKGROUND: National guidelines are rarely followed by immediate change in clinical behaviour. We present our experience of an active educational method for local development and implementation of a guideline. OBJECTIVE: To evaluate the effectiveness of a participative method for developing local clinical guidelines. METHODS: A trial in a district of the effect of guideline development incorporating active participation of intended recipients on subsequent relevant prescribing. It was carried out in Wirral Family Health Services Authority district (the Wirral peninsula) comprising 69 general practices covering a population of 345,763. An exemplar guideline on 'hypertension in the elderly' was developed by the method described. The principal recommended drug was bendrofluazide 2.5 mg once daily. The differences in prescribed daily doses (PDD) of bendrofluazide 2.5 mg tablets per quarter per 1000 prescribing units (age-weighted population) between the intervention district and England as a whole was measured. RESULTS: Comparison of the intervention district with England data demonstrates a median difference of 122.49 PDD before and 206.34 PDD after guideline production, this change is statistically highly significant (Mann-Whitney two-tailed P < 0.0001; 95% CI = 36.51-104.77). Grouped regression analysis shows no significant difference (0.89) in slope gradients before guideline production (P = 0.35, 95% CI = -3.97-5.76), but the difference in slope gradients after (12.95) is statistically highly significant (P < 0.0001; 95% CI = 8.17-17.73). The data suggests that the change in clinical behaviour persisted for at least two years. CONCLUSION: Participation of intended recipient general practitioners and local specialists in the development of a guideline by an active educational method as described was followed by a favourable change in clinical behaviour which persisted for at least two years.

Aged↗

PubMed2005

Implementation of social services for the chronically mentally ill in a Polish mental health district: consequences for service use and costs.

BACKGROUND: In accordance with the mental health reform in Poland, from 1970 to 1980 the following mental health facilities were established within the general health system in the Warsaw District of Targowek: general hospital psychiatric ward, day hospital, outpatient clinic (OC), and community mobile team (CMT) with some procedures of assertive community treatment (ACT). In 1998 (according to the Mental Health Act of 1994), within the social welfare system, new community facilities were established in this district with psychosocial rehabilitation programs for the chronically mentally ill. These new social welfare facilities were a vocational rehabilitation center (VCR), community center of mutual help (CCOMH), and specialized social help services at client homes (SSHS). AIM OF THE STUDY: To determine the change of care delivered to chronic psychiatric patients in both the mental health and social welfare systems, and to compare the costs of care during two 2-year periods: before (Period A) and after (Period B) the 1998 implementation of the new social welfare facilities in the Warsaw District of Targowek. METHODS: The sample consisted of 73 chronic psychiatric patients, admitted since 1998 to the new social welfare facilities. The authors evaluated and calculated the costs of the patients' use of mental health facilities during the two years before their first admission to VCR, CCOMH or SSHS in 1998 (Period A: 1996-1998) and their use of mental health and social welfare facilities during the two years after their admission to VCR, CCOMH or SSHS in 1998 (Period B: 1998-2000). RESULTS: In this group of chronic patients, during Period B, the total duration of both full and partial hospitalizations decreased (-75.9% and -78.9% respectively), while the total number of outpatient mental health visits went up (+62.9%). In Period B the new social welfare facilities offered a substantial amount of day care and the global amount of supplied day care increased markedly. The total costs of the mental health system significantly decreased in Period B (-65.7%), but new costs emerged in the social welfare system. Taken together, the total costs of care provided by the two systems in Period B were higher than the costs incurred by the mental health system alone in Period A (+33.9 %), but the increase in the total amount of services delivered was also relevant (+98.3%). The "out of pocket" expenses incurred by patients increased in Period B (+13.9%). DISCUSSION: The activity of the new social welfare facilities (VRC, CCOMH, SSHS) seems to reduce both full time and partial hospitalizations. Despite the increasing costs of medication reimbursement, and the increased use of CMT and OC, the overall costs for the mental health system were substantially reduced. The decrease in day hospital use is probably due to the large amount of daily social support and home services offered in VRC, CCOMH and SSHS. The results emphasize the importance of evaluating the coordination of care for chronically mentally ill patients in the mental health and social welfare systems.

Adult↗

PubMed2003

PRIME--PRocess modelling in ImpleMEntation research: selecting a theoretical basis for interventions to change clinical practice.

BACKGROUND: Biomedical research constantly produces new findings but these are not routinely translated into health care practice. One way to address this problem is to develop effective interventions to translate research findings into practice. Currently a range of empirical interventions are available and systematic reviews of these have demonstrated that there is no single best intervention. This evidence base is difficult to use in routine settings because it cannot identify which intervention is most likely to be effective (or cost effective) in a particular situation. We need to establish a scientific rationale for interventions. As clinical practice is a form of human behaviour, theories of human behaviour that have proved useful in other similar settings may provide a basis for developing a scientific rationale for the choice of interventions to translate research findings into clinical practice. The objectives of the study are: to amplify and populate scientifically validated theories of behaviour with evidence from the experience of health professionals; to use this as a basis for developing predictive questionnaires using replicable methods; to identify which elements of the questionnaire (i.e., which theoretical constructs) predict clinical practice and distinguish between evidence compliant and non-compliant practice; and on the basis of these results, to identify variables (based on theoretical constructs) that might be prime targets for behaviour change interventions. METHODS: We will develop postal questionnaires measuring two motivational, three action and one stage theory to explore five behaviours with 800 general medical and 600 general dental practitioners. We will collect data on performance for each of the behaviours. The relationships between predictor variables (theoretical constructs) and outcome measures (data on performance) in each survey will be assessed using multiple regression analysis and structural equation modelling. In the final phase of the project, the findings from all surveys will be analysed simultaneously adopting a random effects approach to investigate whether the relationships between predictor variables and outcome measures are modified by behaviour, professional group or geographical location.

Biomedical Research↗

PubMed2004

[Implementation of a common clinical path for transurethral resection of prostate (TURP) in multiple hospitals].

PURPOSE: To investigate the length of hospitalization and medical charges when a common clinical path for TURP (transurethral resection of prostate) was implemented in multiple hospitals. PATIENTS AND METHODS: This study included 310 patients in 2001 and 298 in 2002, who were diagnosed with benign prostatic hyperplasia and who underwent TURP in seven hospitals in Japan. While the patients were treated according to the managing methods of each hospital in 2001, the patients were managed using a common clinical path in 2002, on which we conferred and established in 2001. We investigated the change of various outcome indicators before and after implementation of the common clinical path. RESULTS: The background of patients and surgical outcome in 2002 were equal to those in 2001, except in incidence of preoperative urinary tract infection, general anesthesia and blood transfusion, and number of surgeons. Implementation of a common clinical path shortened the pre- and postoperative hospital stay, duration of bed rest, administration of antibiotics and Foley catheter indwelling, and reduced the standard deviation of these indicators. The total medical charge decreased from 515,439 to 491,935 yen. However, outcomes were considerably different among the seven hospitals. Multivariate analyses identified the hospitals, cognitive impairment, preoperative indwelling catheter and preoperative variance as the factors affecting preoperative hospital stay, and the hospitals, co-existing disease, blood transfusion, postoperative urinary tract infection and postoperative variance as factors affecting postoperative stay. Based on these analyses, we determined four exclusion criteria against using a common clinical path: 1) patients requiring examination or surgery other than TURP simultaneously, 2) patients whose ADL disturbance, cognitive impairment, past history and/or coexisting disease are expected to affect postoperative convalescence, 3) patients with a preoperative indwelling catheter just before operation, and 4) patients with preoperative urinary tract infection. By excluding 122 (39.4%) and 129 (43.3%) patients fulfilling the above criteria in 2001 and 2002, respectively, there were reduction in the length of pre- and postoperative hospital stay, and the total admission fee. Furthermore, there were decrease in their standard deviations. CONCLUSIONS: A common clinical path was valid for reducing variance of the critical indicators affecting the clinical course of TURP and shortening the pre- and postoperative stay in the multiple hospitals. It is mandatory to establish the standard perioperative management for TURP from the viewpoint of urologists, under the circumstances of the impending introduction of the Diagnosis Procedure Combination (DPC).

Aged↗

PubMed1994

The psychosocial impact of implementing a mammography screening campaign in an Australian community.

We examined the psychosocial impact of implementing a generalised campaign to promote mammography screening in an Australian inner city community. Prior to the campaign, telephone interviews were conducted with 628 randomly selected women aged 45-70, 285 in central Sydney (where the screening programme operated) and 343 from the rest of Sydney. A second cross-sectional survey was conducted two years after the campaign commenced. The campaign achieved an estimated 21% attendance rate in an eligible population of 43,000 women over a period of 22 months. Overall the campaign reached a large section of the eligible community, with 70% of women being aware of the van's existence. In addition, the proportion of women who reported being exposed to 'a moderate amount' or 'quite a lot' of information about screening increased by almost 20%. However, two thirds of women still reported being exposed to 'only a little' or no information at all. Attendance was achieved largely in the absence of improvements in knowledge and attitudes. Where change did happen, it occurred in the community overall, rather than being confined to the campaign's target area. Changes were most likely due to general electronic and print media messages, which were largely positive in their tone of reporting on screening. The campaign in one area of central Sydney, Drummoyne, which was much more intense, was successful in encouraging greater awareness of the van and mammography screening, plus greater attendance than in the rest of central Sydney, but had no impact on knowledge or attitudes. There was no demonstrable impact on psychological morbidity.

Adult↗

PubMed2003

Implementing potentially better practices to improve neonatal outcomes after reducing postnatal dexamethasone use in infants born between 501 and 1250 grams.

OBJECTIVE: The purpose of this article is to describe how a neonatal intensive care unit (NICU) was able to reduce substantially the use of postnatal dexamethasone in infants born between 501 and 1250 g while at the same time implementing a group of potentially better practices (PBPs) in an attempt to decrease the incidence and severity of chronic lung disease (CLD). METHODS: This study was both a retrospective chart review and an ongoing multicenter evidence-based investigation associated with the Vermont Oxford Network Neonatal Intensive Care Quality Improvement Collaborative (NIC/Q 2000). The NICU specifically made the reduction of CLD and dexamethasone use a priority and thus formulated a list of PBPs that could improve clinical outcomes across 3 time periods: era 1, standard NICU care that antedated the quality improvement project; era 2, gradual implementation of the PBPs; and era 3, full implementation of the PBPs. All infants who had a birth weight between 501 and 1250 g and were admitted to the NICU during the 3 study eras were included (era 1, n = 134; era 2, n = 73; era 3, n = 83). As part of the NIC/Q 2000 process, the NICU implemented 3 primary PBPs to improve clinical outcomes related to pulmonary disease: 1) gentle, low tidal volume resuscitation and ventilation, permissive hypercarbia, increased use of nasal continuous positive airway pressure; 2) decreased use of postnatal dexamethasone; and 3) vitamin A administration. The total dexamethasone use, the incidence of CLD, and the mortality rate were the primary outcomes of interest. Secondary outcomes included the severity of CLD, total ventilator and nasal continuous positive airway pressure days, grades 3 and 4 intracranial hemorrhage, periventricular leukomalacia, stages 3 and 4 retinopathy of prematurity, necrotizing enterocolitis, pneumothorax, length of stay, late-onset sepsis, and pneumonia. RESULTS: The percentage of infants who received dexamethasone during their NICU admission decreased from 49% in era 1 to 22% in era 3. Of those who received dexamethasone, the median number of days of exposure dropped from 23.0 in era 1 to 6.5 in era 3. The median total NICU exposure to dexamethasone in infants who received at least 1 dose declined from 3.5 mg/kg in era 1 to 0.9 mg/kg in era 3. The overall amount of dexamethasone administered per total patient population decreased 85% from era 1 to era 3. CLD was seen in 22% of infants in era 1 and 28% in era 3, a nonsignificant increase. The severity of CLD did not significantly change across the 3 eras, neither did the mortality rate. We observed a significant reduction in the use of mechanical ventilation as well as a decline in the incidence of late-onset sepsis and pneumonia, with no other significant change in morbidities or length of stay. CONCLUSIONS: Postnatal dexamethasone use in premature infants born between 501 and 1250 g can be sharply curtailed without a significant worsening in a broad range of clinical outcomes. Although a modest, nonsignificant trend was observed toward a greater number of infants needing supplemental oxygen at 36 weeks' postmenstrual age, the severity of CLD did not increase, the mortality rate did not rise, length of stay did not increase, and other benefits such as decreased use of mechanical ventilation and fewer episodes of nosocomial infection were documented.

Anti-Inflammatory Agents↗

PubMed2001

The development of a national oral health promotion programme for pre-school children in England.

Dental caries amongst pre-school children remains a significant dental public health problem in the UK. The well-developed and extensive treatment and preventive services in the UK have failed to effectively prevent dental caries in a significant proportion of pre-school children, especially within disadvantaged communities. This paper outlines the development of an innovative national oral health promotion programme in England which has targeted the carers of pre-school children attending day care facilities. Extensive background research informed the approach of the programme and the resource requirements. Particular emphasis in the programme has been on the development of policies and guidelines in day care settings that promote oral health. Key features of the programme have been the integration of oral health and nutrition, and joint working across sectors and professional disciplines. An evaluation framework, which outlines a range of outcome measures that can be used to assess the effects and impact of the programme, is also described.

Child Day Care Centers↗

PubMedDate not supplied

Sticking together! A creative approach to documenting insulin double checks.

Patient care and family teaching are the heart of the rehabilitation staff nurse's role. Documentation of the various aspects of patient care and family teaching is a necessary but time-consuming process. In this article you will learn how the nurses of one rehabilitation center welcomed a creative time-saving method of working together to improve documentation compliance for double checking insulin administration. The development of the process, education of the staff and the outcomes are included.

Documentation↗

PubMed2006

Barriers to the provision of evidence-based psychosocial care in oncology.

Meeting the psychological, social and physical needs of people with cancer is a challenge for individual health practitioners, health administrators and health policy makers. However, there is a considerable gap between recommended best-evidence psychosocial and supportive care and actual practice. This paper provides a discussion of the reasons for this gap using the precede-proceed model as a theoretical framework. The model is a useful way of classifying potential barriers to the application of recommended best practice into three categories: predisposing factors which influence motivation to behave in a particular way, enabling factors which facilitate the enactment of the behaviour and reinforcing factors which increase the likelihood that the behaviour will be maintained over time. Ways of addressing these barriers are proposed and discussed.

Attitude of Health Personnel↗

PubMedDate not supplied

Compliance in a screening program for neuroblastoma.

BACKGROUND: The Quebec Screening Program for neuroblastoma was undertaken to determine if routine screening of infants for neuroblastoma would decrease the mortality rate from this cancer. All 476,603 children born in Quebec during a 5-year period (1989 to 1994) were offered this screening at ages 3 weeks and 6 months. Through various strategies, an attempt was made to attain the highest level of voluntary compliance possible. METHODS: Each screening consisted of the analysis of the catecholamine metabolites vanillylmandelic acid and homovanillic acid on a dry, urine-saturated filter paper mailed to a central laboratory by the parents. The strategies employed to optimize compliance consisted of increasing the awareness of the parents, health professionals, and the public about neuroblastoma and the screening program. RESULTS: The population responded well to this public health measure, with a 91% compliance rate at 3 weeks and a 74% compliance rate at 6 months. CONCLUSIONS: A well-informed population accustomed to voluntary screening for metabolic disease in infants responds well to screening for cancer.

Female↗

PubMedDate not supplied

Tobacco cessation and youth: the feasibility of brief office interventions for adolescents.

BACKGROUND: The prevalence of tobacco use among adolescents remains high and the great majority of adult smokers begin smoking prior to the age of 18. While there have been a number of primary prevention projects in communities and schools, less attention has been given to smoking cessation for adolescents. This paper reviews the literature on the theory and practice of cessation as applicable to adolescents. METHODS: The relevant literature was culled from a MEDLINE search and supplemented with secondary searches from those articles. RESULTS: There have been few studies on brief interventions for adolescent smoking cessation in health care settings. However, there are several models for smoking cessation that are either applicable to or designed for adolescents. Pharmacologic treatments are also beginning to be used. CONCLUSIONS: There is a great need for the development and evaluation of models for adolescent smoking cessation in health care settings. Recent developments, however, give cause for optimism in helping adolescent smokers in tobacco cessation.

Adolescent↗

PubMed1997

"Unbundling" of state hospital services in the community: the Philadelphia State Hospital story.

This paper describes the organizational, financial, and programmatic changes surrounding the closure of Philadelphia State Hospital, and the conceptual model employed for "unbundling" or disaggregating the state hospital's services into community programs run by private non-profit agencies. The current status of the project is discussed as well as the long-term policy and research questions that remain to be answered.

Community Mental Health Services↗

PubMed2005

Institutionalization of social and behavioral risk factor surveillance as a learning system.

OBJECTIVES: This paper extends further the systematic nature of social and behavioral risk factor surveillance by showing how it becomes a learning system. The authors argue that such a systematic approach will lead to a better informed public health practice and a better understanding of key public health concerns such as obesity. METHODS: This paper is based on methods developed over some 25 years of experience in designing and operating behavioral risk factor surveillance systems. Measurement issues still remain a key concern and special attention is paid to the role of time as a critical variable in developing a surveillance system. RESULTS: The paper lays out five critical areas for attention if a system is to be considered a learning system. Examples are given from ongoing surveillance systems that have developed a base for a learning system and notes how these are institutionalized. CONCLUSIONS: In the ideal case a learning system based on sociobehavioral surveillance is dependent on data being collected continuously with careful attention paid to the analytical challenges of such complex data. This is an ideal systematic approach that has not been realized in most surveillance systems now available.

Cross-Sectional Studies↗

PubMed2004

[Problems introducing a pediatric poisoning treatment set].

Between 1995 and 1998 the Berlin poison center conducted a case-control study supported by the Ministry of Science and Technology, the Berlin Medical Association, a health insurance company, and the Berlin Pediatric Society to test the efficacy of a pediatric poisoning treatment set. The aim of the study was to induce parents of small children to call the poison center immediately in cases of unintentional poisonings at home and to administer activated charcoal if advised to do so by the poison center specialist. This was achieved by handling over a so-called "emergency kit" to 24,000 parents during the regular pediatric office check-up when the children were 10-12 months of age. When an accident occurred, parents with an emergency kit at hand were able to give activated charcoal within 14 min compared to 51 min without this aid. Problems arose when attempts were undertaken to introduce the emergency kit into the routine counseling sessions throughout the country: restrictions imposed by the pharmaceutical law, lack of interest shown by pharmaceutical companies, and diverging responsibilities at county and federal political levels and between different health insurance companies have hitherto prevented the realization of this evidence-based method.

Administration, Oral↗

PubMed2002

Experience with the clinical development of influenza vaccines for potential pandemics.

During normal interpandemic influenza seasons, immune responses to vaccines are quite predictable and meet the licensing criteria of the European Union (EU) Committee for Proprietary Medicinal Products (CPMP). In a pandemic situation, large sections, if not all of the community will be immunologically naïve and therefore new immunisation strategies will be needed. In 1976 and 1977 H1N1 vaccines were prepared and tested clinically. To stimulate 'protective' antibody responses, two doses of vaccine were needed in people below the age of 24 years (no previous experience of H1N1 virus), whereas one conventional dose was adequate in older people. In 1997, the highly pathogenic avian influenza H5N1 virus caused widespread concern when it infected man, with lethal effects. Due to safety concerns it was necessary to adopt new strategies for vaccine development and one such strategy was to produce vaccine from an avirulent H5N3 virus, A/Duck/Singapore-Q/F119-2/97. Clinical trials of a subunit vaccine prepared from A/Duck/Sing/97 virus revealed that even two doses of twice the normal vaccine concentration (i.e. 30 micro g haemagglutinin) were poorly immunogenic, whereas an H5N3 vaccine adjuvanted with microfluidised emulsion (MF) 59 stimulated antibody levels that complied with CPMP criteria after two half strength doses (i.e. 7.5 micro g haemagglutinin).

Clinical Trials as Topic↗

PubMed1995

Human behavior, health education and schistosomiasis control: a review.

This paper examines the role of human behavior in schistosomiasis transmission and control in relation to health education. The literature is reviewed to identify relevant behaviors and to examine progress and constraints in health education, using the primary health care approach. The behavior model by Dunn and the PRECEDE health education model by Green and coworkers are adapted for health education in schistosomiasis control. Because of its focus on the role of individual and community vs outside factors, deliberate vs non-deliberate behavior and health-enhancing and health-maintaining vs health-lowering behavior, Dunn's model can evaluate social, economic, cultural and political factors in schistosomiasis transmission and control that must be considered in health education. The PRECEDE model represents a suitable diagnostic tool for health education planning, intervention and evaluation.

Health Behavior↗