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PubMedDate not supplied

Serum protein polymorphism among Tunisian Berbers: haptoglobin, transferrin and group-specific component subtypes, C3 and BF types.

The polymorphism of serum proteins (Hp, Tf, Gc, C3 and BF) was determined on 210 samples belonging to Berber groups living in three regions of Tunisian. The gene frequencies obtained among the Berbers are different from the the values observed among the other Tunisians. These frequencies differ also within the three-Berber communities. The data collected show that the actual Berber community is genetically heterogeneous. Despite the presence of some African admixture, the gene pool of the Berbers from Tunisia shows large homologies with Middle Eastern groups rather than similarities with North African populations.

Blood Proteins↗
PubMedDate not supplied

Isoelectric focusing studies of transferrin and haptoglobin subtypes in an Australian white population.

This investigation presents the results of Hp and Tf subtyping of sera from 307 Australian whites by means of isoelectric focusing. Five Hp alleles were detected, these being Hp1F = 0.168, Hp1S = 0.235, Hp2FF = 0.003, Hp2FS = 0.561 and Hp2SS = 0.033. In the Tf system six alleles were found, TfC1 = 0.761, TfC2 = 0.176, TfC3 = 0.054, TfC6 = 0.002, TfB = 0.006 and TfD = 0.002. The usefulness of IEF together with modifications was highlighted for differentiating Tf and Hp subtypes; in particular, the absence of Hp2FF and Hp2SS in some earlier studies could be related to the technique used. The implication of the simultaneous presence of B and D transferrin variants in Caucasian populations is discussed.

Alleles↗
PubMedDate not supplied

Linkage of the gene for uncoupling protein to esterase-1,2 and haptoglobin in the rat.

Genetic analysis of a (BN x ACI)ACI backcross for the biochemical markers Es-1 and Es-2 (linkage group V) and a microsatellite marker of Ucp (chromosome 19) revealed linkage between these three loci. This linkage relationship confirms that in the rat linkage group V genes are located on chromosome 19. Genetic analysis of a (BN x LEW)LEW backcross showed that Hp is linked to Ucp, thus indicating that the Hp locus is also located on chromosome 19. These results substantiate the linkage homology of RNO 19, MMU 8, and HSA 16.

Animals↗