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PubMedDate not supplied

Methamphetamine laboratory explosions: a new and emerging burn injury.

The proliferation of clandestine methamphetamine laboratories (meth labs) as a result of the growing popularity of the drug has resulted in an increasing incidence of burn injuries associated with laboratory accidents. We undertook this study to characterize these injuries. Fifteen consecutive patients were identified and case-matched by age and TBSA to 45 control subjects. Most meth lab patients were men, Caucasian, unemployed, and positive for polysubstance abuse. Resuscitation requirements were 1.8 times greater in these patients. There was a higher incidence of inhalational injury corresponding to higher intubation and tracheostomy rate and longer ventilator days among meth lab patients. The rate of nosocomial pneumonia, skin graft loss, and mortality were not different between the two groups. Meth lab injury is unique and requires more critical care resources. It also is associated with lack of insurance coverage and poor follow-up after injury. This injury has a significant impact not only on patients but also on the healthcare system.

Accidents↗
PubMed1991

[Early effects of explosion on hearing threshold and activities of Na+-K+-ATPase and succinic dehydrogenase in the stria vascularis of guinea pigs].

Slow cortex responses to several frequencies were recorded in guinea pigs before and after intense impulse noise exposure. Guinea pigs were decapitated 90 minutes after the exposure. Besides scanning electron microscopic analysis of cochleas, activities of Na(+)-K(+)-ATPase and SDH in the stria vascularis (SV) corresponding to 4 kHz were studied with histochemical methods under light microscope. Densities of histochemical reaction products and cross sections of the SV were measured with image analysis system. Activities of Na(+)-K(+)-ATPase and SDH in the SV decreased significantly in PTS group (P less than 0.01, P less than 0.05). There was no significant change in TTS group. It revealed that decrease of Na(+)-K(+)-ATPase and SDH in the SV may contribute to remarkable hearing threshold shift besides mechanical destruction by noise. Metabolic disturbance may aggravate hair cell damage. Direct damage of the SV caused by intense impulse noise may be one of the causes of PTS.

Animals↗
PubMed1991

[The potentials for hyperbaric oxygenation in the combined treatment of the victims of explosive mine wounds to the extremities].

Hyperbaric oxygenation was used in the combined post-operative treatment of 63 victims with distal segments of lower extremities torn off or damaged by mine and burst effect. The patients consecutively received medicamentous therapy, which improved tissue microcirculation (rheopolyglucinum, haemodesum), surgical intervention, course of hyperbaric oxygenation, and after it anticoagulant preparations (heparinum) were used. The article shows that the combined application of hyperbaric oxygenation and medicinal preparation, that improve microcirculation in traumatized tissues, has a pathogenetic approvement.

Adult↗