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PubMedDate not supplied

[Check-list for inspection in banks].

We suggest a checklist for inspection in banks. The checklist is composed of 14 schedules where information on bank clerks and buildings is collected. Principle risk factors are analysed (workplaces, lighting and noise, air quality, emergency management). The critical points are observed and the times of intervention are established. Then follows data processing and the reports are transmitted to the employer. The checklist, tested on 250 workplaces, allows us to identify the interventions having priority to be realized through appropriate planning. A quantitative evaluation of the risk is matched with immediate and brief operative indications. The situations to improve are: cleanliness of workplaces, thermal comfort, electricity/telephone wires. The checklist seems to be a valid instrument for the evaluation of risk factors, their management and times of intervention. Such instrument simplifies, moreover, the employer choices of intervention.

Humans↗
PubMedDate not supplied

[The OCRA method: updating of reference values and prediction models of occurrence of work-related musculo-skeletal diseases of the upper limbs (UL-WMSDs) in working populations exposed to repetitive movements and exertions of the upper limbs].

BACKGROUND: The paper considers a database of old (already published) and new data concerning 23 groups of workers (Total number of subjects examined=5373) with different levels of exposure to repetitive movements of the upper limbs: for all these groups data were available regarding exposure indexes (OCRA index and Checklist "OCRA" score) and clinically determined UL-WMSD outcomes (PA=Prevalence of workers Affected by one or more UL- WMSDs; PC=Prevalence of single diagnosed Cases of an UL- WMSDs). OBJECTIVES: Using these data, the paper aimed at presenting and discussing the results obtained in order to estimate: new critical values of OCRA index for discriminating different exposure levels (green, yellow, red areas); new prediction models of expected PA and PC in exposed populations based on exposure indexes. METHODS: New critical values of the OCRA index (and, consequently, of the checklist score) were estimated by an original approach in which data of the effect variable PA in a reference population not exposed to the specific risks were combined with the regression function between OCRA and PA, as resulting from the 23 available groups. RESULTS: The resulting critical values and the consequent classification system of the OCRA index and of the checklist score are synthetically reported in the following table: [table: see text]. The best simple regression functions between exposure indexes (OCRA; checklist) and health outcome variables (PA; PC) were then sought, in order to obtain prediction models of effects starting from exposure. The following were the main prediction models derived from the available set of data (standard error of b in brackets): [formula: see text]. Finally, a multiple regression model was computed for estimating PA (Y) based on OCRA index and gender structure of the group (SEXRATIO=n. females x 100/n. total) with its 5 degrees and 95 degrees percentiles (in brackets); the resulting model was. Y = 2.02 (1.72-2.32) x OCRA + 0.075 (0.035-0.115) x SEXRATIO. This model showed a very high association between the two independent variables and the effect variable (PA) (R2=0.96). DISCUSSION: Discussion of the results obtained considers their intrinsic limits, as they are based on prevalence studies, and also suggests due recommendations and caution in the use of the proposed classification system and prediction models when the OCRA methods are applied for the evaluation of occupational risk associated with repetitive movements of the upper limbs.

Adolescent↗
PubMedDate not supplied

Qualitative assessment of brain anomalies in adolescents with mental retardation.

BACKGROUND AND PURPOSE: The neural basis of mental retardation is poorly understood. This study aimed to characterize structural anomalies of the brain in mental retardation and the relationship between them and the degree of mental retardation. METHODS: Eighty adolescents receiving educational support and 40 controls underwent MR brain imaging and intelligence quotient (IQ) assessment. MR images were evaluated according to a checklist of qualitative brain anomalies by a neuroradiologist blind to group membership. All scans were assessed by a second neuroradiologist to measure interobserver agreement. Ten percent of the studies were randomly selected for assessment of intraobserver agreement. RESULTS: Evaluation of MR images by using the checklist generated results with a high degree of interobserver and intraobserver agreement. Intraclass correlations were 0.93 and 0.75 for interobserver agreement on the total abnormality score and the entire checklist, respectively, and 0.97 and 0.85 for intraobserver agreement on the total abnormality score and the entire checklist, respectively. IQ is negatively correlated with the total abnormality score (P < .001). Subjects with an IQ <70 have a significantly greater total score (P = .003) and a significantly greater score for 12 specific anomalies, including thinning of the corpus callosum (P = .001) and abnormalities of the lateral ventricles. CONCLUSION: Mental retardation is associated with demonstrable brain anomalies, particularly thinning of the corpus callosum and ventricular abnormalities, and with a high total abnormality score. Greater levels of brain anomalies are associated with greater levels of mental retardation as evidenced by IQ.

Adolescent↗
PubMed1990

Psychosocial characteristics of homeless children and children with homes.

A comparison was made of 86 children from 49 homeless Boston families headed by women and 134 children from 81 housed Boston families headed by women. In both groups, the mothers were poor, currently single, and had been receiving welfare payments for long periods. Data were collected from the mothers by personal interview; standardized tests were administered to mothers and children (Denver Developmental Screening Test, Simmons Behavior Checklist, Children's Depression Inventory, Children's Manifest Anxiety Scale, and Child Behavior Checklist. The data indicate that many homeless children and poor children with homes have severe and pressing problems. Among preschool children, a higher proportion of homeless children than poor children with homes had one or more developmental delays (P less than .05), although their scores on the Simmons Behavior Checklist were similar. Among school-aged children, the scores of the homeless children were worse than those of the children with homes on the Children's Depression Inventory, Children's Manifest Anxiety Scale, and the Child Behavior Checklist, but only the difference on the Anxiety Scale approached statistical significance (P = .06). Both homeless children and poor children with homes generally had worse scores than most other comparison groups of children. Unless action is taken to improve the lot of all these children, it is likely that many will continue to have significant problems that will seriously hamper their ability to function.

Affective Symptoms↗
PubMed1985

Psychologic factors in low-back-pain disability.

UNLABELLED: Biomechanical tests, physical examination, spinal radiographs, a modified Minnesota Multiphasic Personality Inventory (MMPI), and a psychologic health inventory derived from the Hopkins Symptom Checklist were applied in 321 randomly selected men, ages 18-55. Each subject was evaluated for prior and current low-back pain (LBP) complaints by use of a modification of the McGill pain questionnaire. Subjects were then categorized as having no LBP (n = 106, 33%), moderate LBP (n = 144, 44.8%), and severe LBP (n = 71, 22.1%). Subjects were further subcategorized as not disabled (defined as equal or less than seven days of work lost in the previous year) and disabled (work loss greater than seven days in the prior year). RESULTS: cumulative scores of the Hopkins Checklist showed that a mean score for no LBP equaled 2.5 +/- 2.9; moderate LBP was 4.3 +/- 3.2; and severe LBP was 4.6 +/- 3 (p = .0000). The disabled group was significantly different on both MMPI and Hopkins Checklist. The 20 disabled subjects had significant elevations of hypochondriasis (p = .0006) and hysteria (p = .005) when compared with nondisabled subjects with LBP. The mean score for disabled subjects on the Hopkins Checklist was 7.35 +/- 4.49, while the score was 4.17 +/- 3.15 (p = .0001) for the nondisabled subjects with LBP. In the general male population, patients with disabling LBP conditions form a distinctive subgroup comparable to those patients seen in selected LBP clinics.

Adult↗
PubMed1987

Update on the evaluation of instability of the lower cervical spine.

Clinical instability of the cervical spine should be diagnosed accurately in order to avoid both unnecessary treatment and the serious consequences of inadequate treatment. A systematic method for evaluation utilizing a checklist is suggested. The checklist is based on biomechanical analysis, anatomic analysis, experimental data and clinical studies. The elements of the checklist include (1) evaluation of anatomic components; (2) static radiographic measurements of sagittal plane displacements; (3) a dynamic (stretch test) evaluation of displacements; (4) evaluation of neurologic status; and (5) a consideration of future anticipated loads to the spine. Based on an analysis of these elements and an assignment of numerical values to each, the stability or instability of the spine can be determined. This systematic checklist approach is recommended as a useful method for evaluating clinical instability, given the currently available knowledge. This methodology and current knowledge about the complex problem of spinal instability have certain limitations. Progress will come with more biomechanical experimental studies and controlled prospective clinical studies.

Biomechanical Phenomena↗
PubMed1981

Detection of adverse drug reactions in a clinical trial using two types of questioning.

Two methods of assessing adverse drug effects-an open-ended question versus a checklist-were compared in a clinical study involving 515 patients being treated with bacampicillin for gonorrhea. Results indicate that adverse reactions are reported more frequently if a checklist is used. However, it was also observed that more serious side effects are usually reported in response to an open-ended question rather than a checklist. Thus it was concluded that the optimal procedure for assessing adverse reactions is to record responses to both an open-ended question and a checklist.

Ampicillin↗
PubMed1994

Educating educators in GLP documentation.

Professionals in academia usually are not trained in documenting their research activities to the extent and detail mandated under Good Laboratory Practice (GLP) regulations. To assist researchers at the University of Arizona in implementing a GLP program, the university's Quality Assurance Unit (QAU) has written procedures and checklists detailing various aspects of GLPs. Since a key to the successful implementation of GLPs is comprehensive documentation in laboratory notebooks of research activities, information and guidelines are provided in a checklist format. Training seminars are also provided to discuss the use of the checklists. Checklists in conjunction with training seminars provide an important mechanism to ensure that all appropriate information has been recorded for verifiable, reproducible, and traceable documentation of project study results.

Arizona↗
PubMed1993

Patient-reported symptoms and adequacy of dialysis as measured by creatinine clearance.

A patient-reported checklist was used to assess adequacy of dialysis as measured by 24-hour creatinine clearance in 40 patients on chronic peritoneal dialysis. The checklist consisted of 13 symptoms, each scored from 0-5 with 0 = absent and 5 = severe. The total possible score was 0-65. Patients completed the checklist at the time of 24-hour dialysate and urine collections (in those with residual function) for creatinine clearance (CrCl). Arbitrary grouping by total CrCl in liters/week/1.73 m2 placed patients in one of two groups: those with CrCl < or = 48 L/week (n = 12) and those with CrCl > 48 L/week (n = 28). Patient age, sex, diabetes mellitus, months on peritoneal dialysis, mode of peritoneal dialysis, and hematocrit were not different between the two patient groups. More patients with CrCl > 48 L/week had endogenous renal function (19/28 vs 2/12, p = 0.004). The median total scores for the two patient groups were not significantly different (17 in those with CrCl < or = 48 L/week vs 13.5 in those with CrCl > 48 L/week, p = 0.40). The correlation between total score and CrCl was negative in both patient groups and stronger in those with the lower CrCl (-0.55 vs -0.44). Nausea/vomiting, fatigue, and weakness were the best predictors of CrCl < or = 48 L/week (-0.53, -0.56, -0.49, respectively). The checklist can identify patients with low CrCl and may be useful for following patients over time and altering dialysis prescriptions.

Adult↗
PubMed1997

Parental disclosure of child psychosocial concerns: relationship to physician identification and management.

BACKGROUND: Physician identification and management of psychosocial problems in children is related to parental disclosure. The purpose of this research was to evaluate a method of prompting parental disclosure of such problems and to determine the impact of parental disclosure on family physicians' identification of and intervention for childhood psychosocial problems. METHODS: Participants were parents and physicians of 60 children between the ages of 3 and 10 years attending an ambulatory care clinic of a community-based, university-affiliated family medicine training program. Parents completed the Child Behavior Checklist and also indicated whether psychosocial problems were discussed or managed. Physicians completed a checklist about the psychosocial status of the child and potential interventions for identified problems. One half of the participating parents formed the experimental group and were also asked to note their concerns on a Psychosocial Checklist for Children and to discuss these concerns with their child's physician; the other half of parents received no such checklist and acted as the control group. All interactions between parents and physicians were videotaped. RESULTS: The number of parental psychosocial disclosures, but not the number of parents who disclosed them, was significantly higher for the experimental group. Physicians were three times as likely to identify a psychosocial problem and 10 times as likely to intervene when parents discussed psychosocial concerns. CONCLUSIONS: Parents' disclosure of psychosocial concerns to their child's physician increases the likelihood of physicians identifying and intervening for these problems. The finding that physicians intervened for psychosocial problems even when they failed to record these problems suggests that research needs to focus on measuring both intervention and identification.

Child↗
PubMed1993

Psychosocial aspects of strabismus study.

OBJECTIVE: To assess the psychosocial implications of growing up with and living with socially noticeable strabismus. DESIGN: Self-report mailed questionnaire and the Hopkins Symptom Checklist. SETTING: Patients with strabismus who were seen at the University of California, Davis, Medical Center, Department of Ophthalmology, from 1976 to 1989. PARTICIPANTS: Forty-three female and male subjects aged 15 years or older who had a history of childhood strabismus that was uncorrected or incompletely corrected past the age of 13 years. INTERVENTION: None. MAIN OUTCOME MEASURES: Participants' responses to our survey and to the Hopkins Symptom Checklist. RESULTS: Strabismus had a negative impact on many aspects of our subjects' lives. They report difficulty with self-image, securing employment, interpersonal relationships, school, work, and sports. Furthermore, difficulties encountered did not go away after childhood, rather, the problems encountered by our subjects intensified in the teenage and adult years. Subjects demonstrated generalized higher levels of distress on the Hopkins Symptom Checklist than age- and sex-matched controls (P < .01). CONCLUSIONS: Psychosocial difficulties relating to socially noticeable strabismus are not just a problem for school-children but also for teenagers and adults. Correction of strabismus in the older teenager or adult may offer them improvement in psychosocial functioning, a benefit not previously reported in the literature.

Adolescent↗
PubMed2000

Impact of tonsillectomy and adenoidectomy on child behavior.

OBJECTIVE: To measure the impact of tonsillectomy and adenoidectomy (T&A) on children's behavioral and emotional problems using a standardized assessment. DESIGN: Prospective study. SETTING: Tertiary care children's hospital. PATIENTS: Thirty-six children, aged 2 through 18 years, with symptoms of nighttime snoring, observed apneas, and daytime mouth breathing and physical examination results demonstrating 3+ or 4+ tonsils scheduled for T&A. INTERVENTION: Parents completed a standard survey of their children's symptoms of sleep apnea and a standardized measure of children's competencies and problems, the Child Behavior Checklist for ages 2 through 3 years or 4 through 18 years, before T&A and 3 months postoperatively. MAIN OUTCOME MEASURE: The Child Behavior Checklist total problem score. RESULTS: The preoperative Child Behavior Checklist total problem score was consistent with abnormal behavior for 10 children (28%). After T&A (n = 15), only 2 scores were abnormal, but the change was not statistically significant. In contrast, the mean total problem score was 7.5 points lower after surgery (95% confidence interval, 5.1-9.7), indicating a significant decrease (P<.001, matched t test). CONCLUSIONS: This pilot study demonstrates a high prevalence (28%) of abnormal behavior in children undergoing T&A for chronic upper airway obstruction. Scores on a standardized measure of behavior improve following T&A, but larger studies with increased statistical power are needed to clarify the degree of improvement and its clinical importance.

Adenoidectomy↗
PubMed2002

Persistence of posttraumatic stress in violently injured youth seen in the emergency department.

OBJECTIVE: To determine if symptoms of posttraumatic stress, initially evaluated in the emergency department (ED) setting, persist over time. DESIGN: Prospective cohort study. SETTING: Two urban, academic medical center EDs. PATIENTS: Sixty-nine injured patients, aged 12 to 24 years, were assessed for acute posttraumatic stress symptoms at the time of their enrollment in an ongoing ED-based study of intentional youth violence, and assessed for posttraumatic stress symptoms up to 5 months later. MAIN OUTCOME MEASURES: The Immediate Stress Reaction Checklist, administered during the ED visit, and the Symptom Checklist of the Child and Adolescent Trauma Survey, administered during routine telephone follow-up. RESULTS: Patients in the emergency department reported a range of acute stress symptoms on the Immediate Stress Reaction Checklist, with 25% reporting clinically significant distress. On follow-up assessment, 15% reported significant posttraumatic stress symptoms. The severity of acute stress symptoms was strongly associated with the severity of posttraumatic stress symptoms at follow-up (r = 0.55, P<.005). Age, sex, injury type, and time from injury to follow-up were not associated with the degree of acute stress or posttraumatic stress symptom severity at initial or follow-up assessment. CONCLUSION: This study provides preliminary evidence that acute stress symptoms, assessed in the ED in the immediate aftermath of a traumatic injury, are useful indicators of risk for later posttraumatic stress.

Academic Medical Centers↗
PubMed1993

Behavioral adaptation to human immunodeficiency virus-seropositive status in children and adolescents with hemophilia.

OBJECTIVE: To examine the behavioral adaptation to human immunodeficiency virus (HIV)-seropositive status, as defined by parental report, in children and adolescents with hemophilia. RESEARCH DESIGN: A clinical descriptive study of two groups of patients as part of a longitudinal design. SETTING: A university-based comprehensive hemophilia center and department of neurology acquired immunodeficiency syndrome dementia center. PATIENTS: Forty-six male children with hemophilia divided into two groups based on HIV-seropositive (n = 18) or -seronegative (n = 28) status. None of the patients were symptomatic for acquired immunodeficiency syndrome. SELECTION PROCEDURES: All pediatric patients with documented factor VII or IX deficiency aged between 4 and 19 years at study onset and their families were eligible to participate. All subjects were recruited without regard to human immunodeficiency virus status. INTERVENTIONS: None. MEASUREMENTS AND RESULTS: Profiles of behavioral adjustment were obtained from parents' reports on the Child Behavior Checklist for the HIV-seropositive and HIV-seronegative groups. The two groups did not differ on any of the major indexes of the Child Behavior Checklist, even after adjusting for maternal education and severity of hemophilia. There also was no difference between the groups when individual cases were examined for the number of child behavior checklist scales falling within a clinically significant range. CONCLUSIONS: The current findings fail to confirm any clear evidence of behavioral problems in an asymptomatic group of HIV-seropositive children and adolescents with hemophilia.

Adaptation, Psychological↗
PubMed2004

Contextual predictors of mental health service use among children open to child welfare.

BACKGROUND: Children involved with child welfare systems are at high risk for emotional and behavioral problems. Many children with identified mental health problems do not receive care, especially ethnic/minority children. OBJECTIVE: To examine how patterns of specialty mental health service use among children involved with child welfare vary as a function of the degree of coordination between local child welfare and mental health agencies. DESIGN: Specialty mental health service use for 1 year after contact with child welfare was examined in a nationally representative cohort of children aged 2 to 14 years. Predictors of service use were modeled at the child/family and agency/county levels. Child- and agency-level data were collected between October 15, 1999, and April 30, 2001. SETTING: Ninety-seven US counties. PARTICIPANTS: A total of 2823 child welfare cases (multiple informants) from the National Survey of Child and Adolescent Well-being and agency-level key informants from the participating counties. MAIN OUTCOME MEASURES: Specialty mental health service use during the year after contact with the child welfare system. RESULTS: Only 28.3% of children received specialty mental health services during the year, although 42.4% had clinical-level Child Behavior Checklist scores. Out-of-home placement, age, and race/ethnicity were strong predictors of service use rates, even after controlling for Child Behavior Checklist scores. Increased coordination between local child welfare and mental health agencies was associated with stronger relationships between Child Behavior Checklist scores and service use and decreased differences in rates of service use between white and African American children. CONCLUSIONS: Younger children and those remaining in their homes could benefit from increased specialty mental health services. They have disproportionately low rates of service use, despite high levels of need. Increases in interagency coordination may lead to more efficient allocation of service resources to children with the greatest need and to decreased racial/ethnic disparities.

Affective Symptoms↗
PubMed2001

The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials.

To comprehend the results of a randomized controlled trial (RCT), readers must understand its design, conduct, analysis, and interpretation. That goal can be achieved only through complete transparency from authors. Despite several decades of educational efforts, the reporting of RCTs needs improvement. Investigators and editors developed the original CONSORT (Consolidated Standards of Reporting Trials) statement to help authors improve reporting by using a checklist and flow diagram. The revised CONSORT statement presented in this article incorporates new evidence and addresses some criticisms of the original statement. The checklist items pertain to the content of the Title, Abstract, Introduction, Methods, Results, and Comment. The revised checklist includes 22 items selected because empirical evidence indicates that not reporting the information is associated with biased estimates of treatment effect or because the information is essential to judge the reliability or relevance of the findings. We intended the flow diagram to depict the passage of participants through an RCT. The revised flow diagram depicts information from 4 stages of a trial (enrollment, intervention allocation, follow-up, and analysis). The diagram explicitly includes the number of participants, according to each intervention group, included in the primary data analysis. Inclusion of these numbers allows the reader to judge whether the authors have performed an intention-to-treat analysis. In sum, the CONSORT statement is intended to improve the reporting of an RCT, enabling readers to understand a trial's conduct and to assess the validity of its results.

Publishing↗
PubMed2006

Reporting of noninferiority and equivalence randomized trials: an extension of the CONSORT statement.

The CONSORT (Consolidated Standards of Reporting Trials) Statement, including a checklist and a flow diagram, was developed to help authors improve their reporting of randomized controlled trials. Its primary focus was on individually randomized trials with 2 parallel groups that assess the possible superiority of one treatment compared with another but is now being extended to other trial designs. Noninferiority and equivalence trials have methodological features that differ from superiority trials and present particular difficulties in design, conduct, analysis, and interpretation. Although the rationale for such trials occurs frequently, those designed and described specifically as noninferiority or equivalence trials appear less commonly in the medical literature. The quality of reporting of those that are published is often inadequate. In this article, we present an adapted CONSORT checklist for reporting noninferiority and equivalence trials and provide illustrative examples and explanations for those items amended from the original CONSORT checklist. The intent is to improve reporting of noninferiority and equivalence trials, enabling readers to assess the validity of their results and conclusions.

Publishing↗
PubMed1996

Identification of symptomatologic patterns common to major psychoses: proposal for a phenotype definition.

Our study was designed to identify the underlying symptomatologic structure common to major psychoses as a preliminary step for a phenotype definition. We investigated 1,004 inpatients affected by mood disorders or the schizophrenia spectrum (DSM-III-R) using the OPCRIT checklist (operational criteria checklist for psychotic illness). Symptomatologic structure was extracted by factor analytic techniques and factor scores were first obtained on 500 subjects. A CFA (confirmatory factor analysis) was then conducted on the remaining 504 subjects to evaluate fitness of the model. We identified four factors: excitement, depression, disorganization, and delusion. These factors accounted for 54.6% of the total variance of the OPCRIT checklist symptomatologic subset of 38 items. CFA indices showed a good fit for the model. We identified symptomatologic structures common to major psychoses. The factors identified were confirmed in an independent sample. Two of these symptomatologic structures are partially overlapping with categorical diagnoses (excitement and depression), and two constitute independent psychopathologic traits (delusion and disorganization). The use of "factor-derived scores" in genetic research may add a dimensional definition to the diagnostic subdivision of major psychoses.

Adult↗