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[Postoperative disease: evolution of the concept].

Leriche's La Maladie post-opératoire was described in 1934 as a specific and general reaction to surgery whose systemic symptoms could'nt be understood by the clinical appraisal alone. A laboratory analysis would be necessary. According to Leriche the syndrome could be observed also on other non-surgical trauma. Leriche's concept was ignored by the anglo-saxonic literature but a new scientific approach to the same problem came from Harvard. Walter Cannon with his concept of homeostasis and Henderson, Gamble, Peters and Van Slyke with their definition of the chemical anatomy of the organic fluids and their quantitative analysis, opened the way to Francis Moore's concept of surgery and trauma as metabolic problems. This new biological basis, and the broad enlargement of its spectrum to the whole body, gave a new scope to the surgical practice. Surgery must now be considered as an integrated process, a succession of phenomena defined as pre-operative, per-operative and post-operative representing, nevertheless, a true continuity. To its understanding the post-operative phase cannot be separated from the other phases. La maladie post-opératoire cannot be defined as an unity: there are several post-operative diseases. But the surgical patient must be considered always in the totality of his elements: the somatic or anatomical, the metabolic or physiological and the psychic, forming a complete unity. A global vision versus the old local vision of surgery. This enlarged concept of surgery enables the surgeon to have an intellectual approach similar to that of the physiologist.

General Surgery↗

[A propedeutic concept: the pathologic physiognomy of organs].

After a brief philologic introduction on some correlated concepts of pathogenesis we suggest the concept of pathological physiognomy of the organs. This concept express the conditioning that the peculiar structure, topography and function of an organ exercise on the characteristic configuration (and sometimes even on the possibility) of a pathological process in it. As fondament of this concept we report several examples of pathology.

Humans↗

[The concept of "ganglionitis" in the modern science of the autonomic nervous system].

The authors review the concept of vegetative "ganglionitis" formed in the Soviet literature in the 40-60s. Consider the etiological, clinical and diagnostic aspects thereof. Provide the modern concepts of the clinical manifestations related to the lesions of the paravertebral sympathetic ganglia. Relate some hypotheses concerning the origin of painful phenomena within the framework of the syndrome of reflex sympathetic dystrophy. Indicate that verified lesions of the sympathetic ganglia are associated with well-defined clinical symptoms which absolutely differ in their appearance from the reported descriptions of "ganglionitis", which are unjustifiedly widely used in the Soviet literature over the recent decades. The conclusion is made about the necessity of reviewing the outdated concepts of the pathology of the vegetative sympathetic ganglia from the standpoint of the modern concept of peripheral vegetative insufficiency.

Autonomic Nervous System Diseases↗

[Natural conceptive probability in normal married women].

A total of 1,974 married couples were investigated for natural conception rate and the time required to become pregnant after cessation of contraceptive measure. Among them, 33 couples were infertile due to various causes and 52 couples employed contraceptive method continuously. Therefore, the time intervals of natural conception were available for analysis only in 1,889 couples. Fourteen hundred and sixty-seven women (77.6%) became pregnant within 3 months after exposure to the risk of conception, 1,683 (89.0%) within 6 months, 1,793 (94.8%) within one year and 1,855 (98.0%) within 2 years. The correlations among conceptive probability, history of using contraceptive methods, age of marriage, and menstrual status were discussed.

Adult↗

[5 concepts of disability].

Disablement is a measure indicating how the individual manages or does not manage to cope with the tasks life presents. Different concepts of disablement are applied: Tabular disablement is used to measure the physical resources needed by the individual to undertake an unspecified register of tasks. Medical disablement is a measure of the aggregate resources (physical, mental and social) needed by the individual to undertake an unspecified register of tasks. Occupational disablement is a measure of the aggregate resources needed by the individual to carry out his previous occupation. Economic disablement is a measure of the aggregate resources needed by the individual to carry out some kind of work for which he is fit. Social disablement is a measure of the aggregate resources needed by the individual to maintain contact with other people. The tabular and medical concepts of disablement are used in connection with compensation for non-pecuniary loss. Insurance companies and administrative bodies, when determining the amount of compensation for such losses, lay most of the emphasis on tabular disablement (accident insurance and industrial injury compensation). The courts, when assessing the compensation, attach the main weight to the concept of medical disablement (compensation for non-pecuniary loss). The insurance companies and the administrative bodies have a system that is quite easy to operate, whereas the courts have a system leaving considerable room for discretion. The concepts of occupational and the economic disablement are used when granting compensation for loss of income.(ABSTRACT TRUNCATED AT 250 WORDS)

Classification↗

[From joint to neuromuscular, from mechanics to electronics: the concept of neuromuscular compatibility].

The development of devices to record the functional mandibular kinetics, has permitted the physiological analysis of the masticatory cycles. Therefore, it is possible to consider a functional integration of the corrections, by addition or subtraction to the occlusal surfaces of the teeth. For this purpose, we have established the conditions of a physiological concept of occlusion taking into account the efficiency of the masticatory apparatus through a velocity analysis. This is the N.M.C. concept or concept of Neuro-Muscular Compatibility. This concept has led us to define the ISCA (Intra-Cuspid Spatial Angle), represented by the angle defined in the three spatial planes, by the trajectory of the occlusal contact point of a cusp liding over its opposite, in any excursive opportunity. We have shortly reported the studies by Levin on the SIROGNATOGRAPH and the prospects resulting from these studies. Then, we have studied in greater details the Saphon VISI TRAINER III developed by HOBO and described the various potentials of its use in the GBM Laboratory in Vienna (France), with François DURET. We have also analyzed the specific points which seem to represent the weaknesses of this device and have outlined some solutions to this problem. This approach, within a clinical context, may at term give rise to a complex analyser-expert-system intends to facilitate the establishment of a reliable diagnosis and to control the physiological integration of our procedures. The establishment, at term, of parameters and constants of this function, will guide this progression towards success.

Dental Occlusion↗

Remodeling the pyramid--a concept whose time has come.

It is clear that the traditional treatment program, as illustrated by the pyramid, does not suppress inflammation in most patients with RA to an extent sufficient to prevent joint damage. There is no basis for the concept that slow acting drugs are uniquely disease modifying. Disease modification correlates best with control of inflammation. Contrary to popular wisdom, this has been best demonstrated with prednisone. The arbitrary concept of a drug being either antiinflammatory or disease modifying serves no useful purpose and should be dropped. Many medications provide incomplete or temporary suppression of inflammation, presumably by differing mechanisms of action. Based on this rationale, a therapeutic program is proposed, employing a combination of drugs to control inflammation in the critical early stages of RA. With this step-down bridge concept, medications are sequentially withdrawn in contrast to the traditional pyramid, in which they have been sequentially added. Our early experience with patients indicates that toxicity is no greater problem with combined drugs than with the same drugs used individually. Time and comparative observations will be needed to show the optimum combination of drugs and whether the step-down bridge concept will achieve the sought-for and presently unobtained goal of early and sustained control of inflammation, improved quality of life, and prevention of bone and joint damage.

Anti-Inflammatory Agents↗

Quantifying the concepts of rate and acceleration/deceleration of aging.

In this paper, we shall attempt to quantify the rather abstractly and ambiguously used concepts of acceleration of aging and rate or velocity of aging. The use of the phrase "rate of aging", in the gerontological literature, requires that we formalize the concepts so that they may be discussed in a uniform manner. We shall perform this formalization by means of an analogy with various similar concepts from the discipline of physics. This set of analogies leads, quite naturally, to some practical ways in which we may discuss the acceleration of aging. Additionally, these analogies allow us to introduce two forms of acceleration of aging; uniform and non-uniform acceleration. By uniform acceleration, we shall see that we mean an acceleration which is independent of the age of the individual in the population. That is, every individual in the population feels the same magnitude of acceleration, no matter what his age. Non-uniform acceleration is an acceleration which is age-dependent. We shall introduce the concepts of relative acceleration and fraction relative acceleration as a means of deciding whether a population is undergoing uniform or non-uniform acceleration. Finally, these new developments will be applied to C. elegans, to rat, and to C57BL/6J mouse experimental data.

Aging↗

Nephrotic syndrome: a nursing care plan based on current pathophysiologic concepts.

The classic conception of the pathophysiology of the nephrotic syndrome (NS) is now being seriously questioned, on the basis of current research findings. New conceptions of the syndrome, with its proteinuria, hypoalbuminemia, and edema, are providing explanations for the discrepancies between the original theory and clinical data from individual patients, particularly related to edema formation. Many of the edema-preventing mechanisms are normal in patients with NS, but may fail when plasma osmotic pressure falls significantly. Plasma volumes, blood volumes, and blood pressures of patients with NS have been found to be generally normal or slightly increased, in contrast to the classic "hypovolemia" theory. Activation of the renin-angiotension-aldosterone system is variable and cannot fully explain the sodium and water retention. The decreased renal filtration rates and abnormal sodium retention/excretion rates are now best explained by an intrarenal defect, on the basis of multiple research approaches. These research conceptions of the pathophysiology of NS are significant for nurses because they can be used in patient assessment, interpretation of patient data, monitoring during treatment, collaboration about the plan of care, development of nursing care plans, and patient teaching. Several nursing diagnoses may be appropriate for patients with NS: alteration in fluid volume: excess; potential for infection; alteration in nutrition: less than body requirements, potential alteration in comfort; knowledge deficit; and potential disturbance in self-concept: body image.

Humans↗

Andrija Stampar and the concept of positive health.

The literature in the health and medical care field contains a heavy burden of obscure rhetoric and semantic slight of hand. Terms gain a usage which belies the reality to which they refer, code words come to serve as a substitute for thought, and concepts seemingly acquire a life of their own. Such is the case with the concept of positive health. For almost four decades this concept has been bandied about. Often it is raised only to be disclaimed or with the intent to depreciate its relevance. However, it is probably invoked with equal frequency as an ambiguous but reassuring kind of appeal. Discussions of the concept rarely deal with its operational implications and never seem to manifest appreciation of its origin. Attention is here directed to its original formulation and to Andrija Stampar, the person most directly responsible for this, in order to facilitate consideration of its current significance.

Health Promotion↗

On functional concepts for the explanation of visual pattern recognition.

An overview is given covering approximately 30 years of research in the field of functional concepts for the explanation of visual pattern recognition processes. Due to its important role, the Perceptron approach is briefly sketched. This concept, representing to a great extent the present opinion about pattern recognition in the field of visual sciences, is investigated with respect to its invariance properties and its structure. Fundamental facts about the nature of human perception (Gestalt-aspect) and about the processing structure of the visual system are used as qualification criteria. Alternatively, a recent concept that explains the high degree of invariance in visual perception by the evaluation of inner pattern relations is introduced and investigated with respect to its biological plausibility. It is also compared with the Perceptron concept.

Computers↗

[The origin of the eukaryotic cell. I. Historical sources and current state of the concept of symbiotic and autogenic origins of the cell].

The exogenous (symbiotic) conception of the eukaryotic origin is now widely spread. It is based on the recognition of the principle of combination (addition or enclosing) of diverse prokaryotic organisms; so the complicated unicellular eukaryotic organism (eukaryotic cell) was resulted. the principle of combination takes its historical scientific sources from the ideas of Buffon. With reference to the cell this principle was claimed for the first time. In our time the exogenous conception is characterized as a "symbiotic boom", because it is widely used in attempts to explain the origin of all the main organelles of the cell (right up to the micro-bodies). The autogenetic (endogenous) conception is based on the principle of straight phyliation, on the recognition of a successive evolutionary transformation of prokaryotic forms into eukaryotic ones. In this way all the cell organelles may have an endogenous origin. This principle springing from Lamarck has got a contemporary meaning in the doctrine of Darwin. In the next papers the author will present his own analysis and generation of the present day relevant facts to find out which of these two conceptions based on quite different scientific methodological principles may be correct.

Animals↗

[Theoretical concepts of modern pathology (a critique of their medical philosophical foundations)].

Separation of theoretical pathology into an independent branch of science seems to be justified and creation of the Centre of Theoretical pathology in the Heidelberg Academy of Sciences is due and useful. As W. Doerr truly states, the theoretical pathology seems to be over the pathological physiology and general pathology, exerts additional functions, studies questions of the methodology in pathology, defines more exactly and analyzes the notion of disease, other concepts and terms, clarifies early preclinical and clinical disease manifestations, determines sociological and psychological factors of disease. However, we are not in full agreement with our colleagues from the FRG in the definition of "disease" and in the interpretation of such categories as "spirit", "soul", "psychic". K. Rotschuh' suggestion to consider the disease in terms of "body-soul" appears to be interesting but to be productive, it must be linked with the problems of medical psychology. W. Doerr and his colleagues support the dualistic concepts of human nature which is unacceptable for us; they claim that the understanding of the theoretical pathology essence is possible only on the basis of theleology and spirit (theology). As the highest commencenment on the way of the theoretical pathology recognition W. Doerr's categorical declaration that theoretical pathology based on the "gestalttheorie" returns scientists, as he writes" to their great delight, to the possibility of studying "spiritual essence of the disease". In W. Doerr's opinion, studying the concept of theoretical pathology "from the spiritual point of view" will ensure its brilliant future. Of course, we, Soviet pathologists and philosophers, do not reject the significance of the integrity theory in the meaning of the disease psycophysiological integrity, yet we decidedly reject any idealistic concepts. W. Doeer and his colleagues are right that the theoretical pathology stimulates the search of the approaches to the solution of complex biomedical problems, favours the creation of more precise definitions and terminology. Likewise, W. Doerr is right that he sharply condemns the attempts of some pathologists to substitute qualitative differences in pathological processes by quantitative ones; this may result, in his view, in one-sided erroneous conclusions.(ABSTRACT TRUNCATED AT 400 WORDS)

Communism↗

[Development of the autonomy concept in psychoanalytic literature].

The development of an implicit concept of autonomy in Freud's work and the different explicit concepts of autonomy in neo-analysis and ego-psychology is delineated. The contradictory views of a strict psychic determinism and the utopia of freedom stand side by side in early psychoanalysis. They represent its scientific and romantic root. Neo-analysis puts a stress on the romantic tradition and elaborates a philosophical concept of autonomy, while modern ego-psychology follows rather the scientific tradition. All concepts of autonomy are based on a model of psychic health that is related to the idea of a harmonious personality, an ideal which has precursors in German classicism, the renaissance, and the antique.

Freedom↗

Popular medical concepts in Jamaica and their impact on drug use.

Universally, popular medical concepts form the basis of lay understanding of health, disease and cure. In Jamaica these concepts first developed in association with traditional herbal medicine. Now they are applied to the most common forms of primary care: over-the-counter and prescribed drugs. Research findings suggest that where there is disagreement between popular and professional medical models, as is the case in Jamaica, the effect of popular concepts is to increase self-medication and reduce adherence to prescribed medical regimens. To ameliorate this situation and the attendant potential risks for drug consumers, methods for providing needed drug information and improving physician-patient communication are suggested. These suggestions apply not only to Jamaicans living in Jamaica and the United States, but also to members of any group whose ethnomedical concepts differ from the biomedical training of physicians.

Adolescent↗

Models for leprosy. An appraisal of graphic representations of the "spectrum" concept as models and a suggestion for a catastrophe theory model for leprosy.

Graphic representations of the spectrum concept of leprosy are examined in some detail as models for this disease. This reveals that this concept is somewhat inadequate and that the spectrum metaphor may itself be inappropriate because, by its very linearity of logic, it may not be able to depict the nonlinear behavior of leprosy properly. The assumptions underlying this concept and their logical consequences, brought out by the graphic representations, include an invariable relation between CMI and BI, identity of one type of leprosy with one specific level of CMI, a fixed sequence of types, and the consequent impossibility of skipping the sequence. However, our experience with leprosy does not bear out these assumptions. Further, development and progress of leprosy from a normal (nonleprous) state cannot be represented in these models. A search for alternative conceptual models therefore appears reasonable and even necessary. The catastrophe theory (a branch of topology in mathematics) describes a number of models for explaining how continuous causes could produce sudden or discontinuous changes. Of the various catastrophe theory models available, the relatively simple "cusp" model appears capable of application to leprosy. This model, as applied here, requires two control factors (identified tentatively as the amount of dead bacilli and the amount of living bacilli or their indicators) and one pattern of behavior, identified as progress towards limited or extensive disease. This model suggests under what conditions leprosy will change from one type to another and whether that will happen gradually or suddenly. It also suggests that for certain values of control factors the disease may manifest in one of two forms of borderline leprosy, and that lesions very similar to start with can progress to quite different states under similar conditions of change. The behavior of leprosy agrees more or less with that suggested by this model. The cusp model thus seems to: a) provide an insight into the behavior of leprosy, enabling us to understand the dynamics of the disease; b) explain some of its intriguing manifestations; c) ask meaningful questions; and d) plan new therapeutic approaches. Although this is a highly speculative and probably too simple a model, this attempt shows that it is possible to view leprosy outside the framework of the concepts of spectrum scale and polar types of leprosy, the conceptual models which dominate all of our current thinking about the disease.

Humans↗

Children's concepts of health and illness--and implications for health education: an overview.

Research on children's concepts of health and illness has been dominated by two theoretical approaches. The first has been concerned with the delineation of age-related qualitative changes in children's concepts of health and illness and the interpretation of these changes within a Piagetian framework. The second approach, based on expectancy theory from social psychology, has focused on children's perceptions of vulnerability to health problems and the relationship of these to potential health behavior. Both approaches have emphasized children's concepts of illness or of health problems. Thus, there is a dearth of literature on concepts of health per se.

Attitude to Health↗

[The contribution of systems theory and "existential integrative psychotherapy" to the relationship of the concepts "endogenous", "exogenous", "psychogenic", and "sociogenic" in psychic disorders].

Proof is given that the "atomistic" concepts of sickness lead to insolvable contradictions of methodic and logic origin. In this study these contradictions are exemplified and critically analysed, and historical aspects are included. We then propose the dimensions "Interior--Exterior" and "Psychogenous--Somatogeneous" as an heuristic model, dimensions on which any sickness is to be located according to its basic causes. The General System Theory had developed a new formal concept of sickness based on a relatively complete and integral vision of the human being. Nevertheless, the constructs of the General System Theory remain incomplete as they include only objects and their relations, never individual subjects. Wyss however has established explicitely an anthropology of the subject which he connects with his communication orientated concept of sickness. This concept does not judge sickness to be contradictory to health, but both, sickness and health together, form a functional whole on a higher level of abstraction. On this level the organism and its functions, the "interior", represent an inherent component of the "exterior". "Interior" and "exterior"--differentiated in various items--attempt to establish an equilibrium that is always in danger of being desquilibrized.

Communication↗